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217 条记录 (耗时 0.033 秒)

    Certain aminoalkyl glucosaminide phosphate compounds and their use
    92.
    发明授权
    Certain aminoalkyl glucosaminide phosphate compounds and their use 有权
    某些氨基烷基氨基磷酸酯化合物及其用途

    公开(公告)号：US07960522B2

    公开(公告)日：2011-06-14

    申请号：US10888683

    申请日：2004-07-08

    申请人： David A. Johnson ,  David Persing

    发明人： David A. Johnson ,  David Persing

    IPC分类号： C07H17/02 ,  A01N43/04 ,  A61K31/70

    CPC分类号： C07H5/02 ,  C07H11/04 ,  C07H13/04 ,  C07H15/04

    摘要： Compounds that are adjuvants and immunoeffectors are described and claimed. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Compositions and methods for using the compounds as adjuvants and immunoeffectors are also disclosed.

    摘要翻译： 描述和要求保护作为佐剂和免疫作用剂的化合物。 该化合物增加免疫动物的抗体产生，并刺激细胞因子产生并激活巨噬细胞。 还公开了使用化合物作为佐剂和免疫作用剂的组合物和方法。

    Immunoeffector compounds
    94.
    发明授权
    Immunoeffector compounds 有权
    免疫功能化合物

    公开(公告)号：US07501399B2

    公开(公告)日：2009-03-10

    申请号：US11519275

    申请日：2006-09-11

    申请人： David A. Johnson ,  Jory Baldridge ,  C. Gregory Sowell

    发明人： David A. Johnson ,  Jory Baldridge ,  C. Gregory Sowell

    IPC分类号： A01N43/04 ,  A61K49/04

    CPC分类号： C07H15/04 ,  C07H15/26

    摘要： This invention provides compounds containing a 2-deoxy-2-amino-β-D-glucopyranose (glucosamine) glycosidically linked to an cyclic aminoalkyl (aglycon) group. The invention further provides methods for inducing an immune response using the compounds of the present invention in the presence or absence of an antigen. In addition, methods for treating disease with the compounds of the present invention with or without an antigen are also provided in this invention.

    摘要翻译： 本发明提供含有与环状氨基烷基（糖苷配基）基团糖基连接的2-脱氧-2-氨基-β-D-吡喃葡萄糖（葡糖胺）的化合物。 本发明还提供了在存在或不存在抗原的情况下使用本发明化合物诱导免疫应答的方法。 此外，本发明还提供了用或不含抗原用本发明化合物治疗疾病的方法。

    Immunoeffector compounds
    96.
    发明授权
    Immunoeffector compounds 有权
    免疫功能化合物

    公开(公告)号：US07129219B2

    公开(公告)日：2006-10-31

    申请号：US10469620

    申请日：2001-08-03

    申请人： David A. Johnson ,  C. Gregory Sowell

    发明人： David A. Johnson ,  C. Gregory Sowell

    IPC分类号： A01N43/04 ,  A61K49/04 ,  C07G11/00 ,  C07H15/00

    CPC分类号： C07H15/04 ,  C07H15/26

    摘要： This invention provides compounds containing a 2-deoxy-2-amino-β-D-glucopyranose (glucosamine) glycosidically linked to a cyclic aminoalkyl (aglycon) group. The invention further provides methods for inducing an immune response using the compounds of the present invention in the presence or absence of an antigen. In addition, methods for treating disease with the compounds of the present invention with or without an antigen are also provided in this invention.

    摘要翻译： 本发明提供含有环状氨基烷基（糖苷配基）基团糖基化连接的2-脱氧-2-氨基-β-D-吡喃葡萄糖（葡糖胺）的化合物。 本发明还提供了在存在或不存在抗原的情况下使用本发明化合物诱导免疫应答的方法。 此外，本发明还提供了用或不含抗原用本发明化合物治疗疾病的方法。

    Method of installing an edgepiece on a battery plate
    97.
    发明授权
    Method of installing an edgepiece on a battery plate 有权
    将电子白板安装在电池板上的方法

    公开(公告)号：US07077876B2

    公开(公告)日：2006-07-18

    申请号：US10723597

    申请日：2003-11-24

    申请人： David A. Johnson ,  Peter E. Johnson

    发明人： David A. Johnson ,  Peter E. Johnson

    IPC分类号： H01M6/00

    CPC分类号： B26D1/305 ,  B29C53/043 ,  B29C63/0034 ,  B29L2031/3468 ,  H01M2/145 ,  H01M2/18 ,  H01M2/26 ,  Y10T29/10 ,  Y10T29/49108 ,  Y10T29/4911 ,  Y10T29/49112 ,  Y10T29/4987 ,  Y10T29/49915 ,  Y10T29/51 ,  Y10T29/5142 ,  Y10T29/5191 ,  Y10T29/53135 ,  Y10T29/53139 ,  Y10T29/53278 ,  Y10T83/2096 ,  Y10T83/647

    摘要： A method for placing an edge piece on a battery plate includes bending a thin strip of bendable plastic material into an open top, U-shaped channel. The channel is then cut into an edge piece having a length which is substantially equal to the edge of the battery plate which is to be covered. The edge piece is supported with this open top oriented towards a battery plate that is transported toward it in a manner such that the battery plate edge will be inserted into it. Once the edge of the battery plate has been inserted into the edge piece the edge piece is released so that the battery plate can be carried out of the apparatus. An apparatus for accomplishing this includes a feed mechanism which transports the strip of bendable plastic material. A bending mechanism forms this strip into the open top, U-shaped channel. The channel is then fully inserted into an assembly station where a first sensor stops the feed mechanism and a cutter cuts the channel into the proper-sized edge piece. An in-feed conveyor transports a battery plate toward the edge piece, and a support mechanism supports the edge piece while the edge of the battery plate is inserted into it. The support mechanism then releases the edge piece so that it can travel out of the insertion station with the battery plate. A second sensor restarts the feed mechanism once the battery plate is completely out of the assembly station.

    摘要翻译： 用于将边缘片放置在电池板上的方法包括将可弯曲塑料材料的薄条弯曲成开口的U形通道。 然后将通道切割成具有与要被覆盖的电池板的边缘基本相等的长度的边缘件。 该边缘件被支撑，该敞开的顶部朝向电池板，该电池板以使电池板边缘插入其中的方式被输送到电池板。 一旦电池板的边缘已经插入到边缘件中，则边缘件被释放，使得电池板可以从设备中进行。 用于实现这一点的装置包括输送可弯曲塑料材料条的进给机构。 弯曲机构将该条形成为开口的U形通道。 然后将通道完全插入装配站，其中第一传感器停止进给机构，并且切割器将通道切割成适当尺寸的边缘件。 进料输送机将电池板朝向边缘件输送，并且当电池板的边缘插入其中时，支撑机构支撑边缘件。 然后，支撑机构释放边缘片，使其能够与电池板一起移出插入台。 一旦电池板完全脱离装配站，第二个传感器重新启动进给机构。

    Printhead assembly with minimized interconnections to an inkjet printhead
    99.
    发明授权
    Printhead assembly with minimized interconnections to an inkjet printhead 失效

    公开(公告)号：US06607257B2

    公开(公告)日：2003-08-19

    申请号：US09960109

    申请日：2001-09-21

    申请人： Thomas P. Szumla ,  Manh Tang ,  David A. Johnson ,  David S. Madziarz

    发明人： Thomas P. Szumla ,  Manh Tang ,  David A. Johnson ,  David S. Madziarz

    IPC分类号： B41J2938

    CPC分类号： B41J2/04521 ,  B41J2/03 ,  B41J2/04541 ,  B41J2002/022 ,  B41J2002/032 ,  B41J2202/16

    摘要： An inkjet printhead assembly (50) for an inkjet printer having a printhead (10) with a plurality of nozzles (24) and data path and control electronics circuitry (56) operably coupled with the printhead (10) for providing image data that control the flow of ink through the nozzles (24). The nozzles (24) are arranged in sections with at least two heater elements, an upper heater (28a) and a lower heater (28b), predisposed about each nozzle (24), the heater elements configured to actuate a nozzle (24) for printing. The data path and control electronics circuitry (56) comprises a plurality of shift registers (100, 102) configured to drive the nozzles, causing them to deliver ink in the direction of a receiver media, such as paper. Interconnections (54) between the data path and control electronics circuitry (56) and printhead (10) include DATA, CLOCK, LATCH and ENABLE lines which are used to operate the printhead (10) and, in turn, the nozzles (24) via the shift register stages (100, 102). The number of interconnections are minimized by interleaving data to the shift registers between upper and lower heater elements of the printhead (10) or by interleaving the data on the DATA line to the shift register stages (104, 106) for the upper and lower heater elements.

    Test apparatus improved test connector
    100.
    发明授权
    Test apparatus improved test connector 有权
    测试设备改进了测试连接器

    公开(公告)号：US06570393B2

    公开(公告)日：2003-05-27

    申请号：US09156128

    申请日：1998-09-17

    申请人： David A. Johnson

    发明人： David A. Johnson

    IPC分类号： H01H3104

    CPC分类号： G01R1/0416

    摘要： An improvement to contacts for automatic test apparatus used in the testing of semiconductors. At least two contacts with first and second ends for engaging test points of a device under test (DUT) extend the first end different distances toward the DUT. The test apparatus is arranged to support and carry a DUT at a predetermined rate toward the two contacts. The contact with the greatest first end extension, which contacts the DUT first, has the second end connected to ground and the other contact has the second end connected to a test voltage. Each first and second end of said contacts have support means arranged to permit the ends to deflect a predetermined distance under a predetermined force. This permits the apparatus to engage both ends of both contacts at predetermined contact forces. A plurality of sets of contacts with a given extension and/or a plurality of different extensions for sets of contacts can also be used.

    摘要翻译： 对半导体测试中使用的自动测试仪器的触点进行了改进。 至少两个具有用于接合待测器件（DUT）的测试点的第二端和第二端的触头将第一端向DUT延伸不同的距离。 测试装置被布置成以预定的速率向DUT提供并携带DUT朝向两个触点。 与第一端接触DUT的最大的第一端延伸部的接触件具有连接到地的第二端，而另一端子的第二端连接到测试电压。 所述触头的每个第一和第二端具有布置成允许端部在预定力下偏转预定距离的支撑装置。 这允许装置以预定的接触力接合两个触点的两端。 也可以使用具有给定延伸部和/或多个不同延伸部的多组触点，用于触点组。