公开(公告)号：US07282565B2

公开(公告)日：2007-10-16

申请号：US10767374

申请日：2004-01-29

申请人： Audrey Goddard ,  Austin L. Gurney ,  Daniel Tumas ,  William I. Wood

发明人： Audrey Goddard ,  Austin L. Gurney ,  Daniel Tumas ,  William I. Wood

IPC分类号： C07K14/00 ,  C12Q1/68

CPC分类号： C07K14/705 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/30

摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer, and nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing such antigens PRO301, PRO362 or PRO245.

摘要翻译： 本发明涉及治疗和诊断疾病的组合物和方法，其特征在于存在与炎性疾病和/或癌症相关的抗原，以及核苷酸序列，包括表达的序列标签（EST），寡核苷酸探针，多肽，载体和宿主细胞 表达这种抗原PRO301，PRO362或PRO245。

公开(公告)号：US07282562B2

公开(公告)日：2007-10-16

申请号：US10213145

申请日：2002-08-05

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Daniel Tumas ,  Colin K. Watanabe ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Kenneth J. Hillan ,  Daniel Tumas ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C07K1/00 ,  A61K39/00 ,  A61K47/00

CPC分类号： C07K14/4702

摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.

公开(公告)号：US07282561B2

公开(公告)日：2007-10-16

申请号：US10196754

申请日：2002-07-16

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C07K1/00 ,  C07K14/00 ,  C07K16/00 ,  C07K17/00

CPC分类号： C07K14/47 ,  A01K2217/075 ,  A01K2227/105 ,  A61K38/00 ,  C07K14/4748 ,  C07K14/705 ,  C07K14/82 ,  C07K16/28 ,  C07K2319/30 ,  C12Q1/6816 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5082 ,  G01N33/5308 ,  G01N33/574 ,  G01N33/57419 ,  G01N33/57423 ,  G01N33/57434 ,  G01N33/57484 ,  G01N33/57488 ,  G01N33/57492 ,  G01N2500/00 ,  C12Q2563/131 ,  C12Q2527/137

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07279551B2

公开(公告)日：2007-10-09

申请号：US10131813

申请日：2002-04-24

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C07K14/435 ,  C07K19/00 ,  C07H21/04

CPC分类号： C07K14/47 ,  C07K2319/30

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07276577B2

公开(公告)日：2007-10-02

申请号：US10123212

申请日：2002-04-15

申请人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Victoria Smith ,  William I. Wood

IPC分类号： C07K14/435

CPC分类号： C07K14/47

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07273726B2

公开(公告)日：2007-09-25

申请号：US10785221

申请日：2004-02-24

申请人： Sherman Fong ,  Audrey Goddard ,  Austin L. Gurney ,  William I. Wood

发明人： Sherman Fong ,  Audrey Goddard ,  Austin L. Gurney ,  William I. Wood

IPC分类号： C07H21/04 ,  C12P21/06 ,  C12N1/20 ,  C12N15/74

CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K39/395 ,  C07K14/705 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/00 ,  C07K2319/30 ,  G01N33/57484 ,  G01N33/6893 ,  G01N2800/7095

摘要： The present invention relates to compositions and methods of treating and diagnosing disorders characterized the by the presence of antigens associated with inflammatory diseases and/or cancer, and nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing such antigens PRO301, PRO362 or PRO245.

公开(公告)号：US07259238B2

公开(公告)日：2007-08-21

申请号：US10063536

申请日：2002-05-02

申请人： Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  William I. Wood

IPC分类号： C07K14/00 ,  C07K5/00 ,  C12N15/00

CPC分类号： C07K14/47 ,  A61K38/00 ,  C07K14/4748 ,  C07K14/705 ,  C07K14/82 ,  C07K16/18 ,  C07K16/30 ,  C07K16/3023 ,  C07K16/3046 ,  C07K16/3053 ,  C07K16/40 ,  C07K2319/30 ,  C12N5/06 ,  Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07250490B2

公开(公告)日：2007-07-31

申请号：US10187745

申请日：2002-07-02

申请人： Kevin P. Baker ,  Jian Chen ,  Luc Desnoyers ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  James Pan ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood ,  Zemin Zhang

发明人： Kevin P. Baker ,  Jian Chen ,  Luc Desnoyers ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  James Pan ,  Victoria Smith ,  Colin K. Watanabe ,  William I. Wood ,  Zemin Zhang

IPC分类号： C07K1/00

CPC分类号： C07K14/47 ,  A01K2217/075 ,  A01K2227/105 ,  A61K38/00 ,  A61K39/00 ,  C07K14/4748 ,  C07K14/705 ,  C07K14/82 ,  C07K16/00 ,  C07K16/18 ,  C07K16/28 ,  C07K2319/30 ,  C12N9/90 ,  C12N2799/026 ,  C12Q1/6816 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5082 ,  G01N33/5308 ,  G01N33/574 ,  G01N33/57411 ,  G01N33/57415 ,  G01N33/57419 ,  G01N33/57423 ,  G01N33/57434 ,  G01N33/57484 ,  G01N33/57488 ,  G01N33/57492 ,  G01N2500/10 ,  C12Q2563/131 ,  C12Q2527/137

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07244817B2

公开(公告)日：2007-07-17

申请号：US10063586

申请日：2002-05-03

申请人： Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  William I. Wood

发明人： Audrey Goddard ,  Paul J. Godowski ,  J. Christopher Grimaldi ,  Austin L. Gurney ,  William I. Wood

IPC分类号： C07K14/00

CPC分类号： C07K14/47 ,  C07K2319/30

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：US07244816B2

公开(公告)日：2007-07-17

申请号：US09997666

申请日：2001-11-15

申请人： David Botstein ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Margaret Ann Roy ,  Colin K. Watanabe ,  William I. Wood

发明人： David Botstein ,  Audrey Goddard ,  Paul J. Godowski ,  Austin L. Gurney ,  Margaret Ann Roy ,  Colin K. Watanabe ,  William I. Wood

IPC分类号： C07K14/00 ,  A61K39/00

CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K39/00 ,  C07K14/52 ,  C07K14/705 ,  C07K16/18 ,  C07K2319/00 ,  C12N9/00 ,  G01N33/5008 ,  G01N33/5011 ,  G01N33/502 ,  G01N33/57484 ,  G01N33/68 ,  G01N33/6842 ,  Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.