公开(公告)号：US07192594B2

公开(公告)日：2007-03-20

申请号：US10653849

申请日：2003-09-02

Applicant: Deborah Haines ,  Gordon Allan ,  John Ellis ,  Brian Meehan ,  Edward Clark ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly ,  Li Wang ,  Lorne A. Babiuk ,  Andrew A. Potter ,  Philip Willson

Inventor： Deborah Haines ,  Gordon Allan ,  John Ellis ,  Brian Meehan ,  Edward Clark ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly ,  Li Wang ,  Lorne A. Babiuk ,  Andrew A. Potter ,  Philip Willson

IPC: A61K39/12

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/53 ,  A61K2039/552 ,  A61K2039/70 ,  C12N7/00 ,  C12N15/86 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043 ,  C12Q1/701

Abstract: The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in a vertebrate subject. Polynucleotides derived from the viral genome can be used as diagnostic primers and probes.

Abstract translation: 新型PCVII病毒基因组的克隆描述为源自PCVII基因组的蛋白质的表达。 这些蛋白质可用于预防和治疗PCVII感染的疫苗组合物中，以及用于确定脊椎动物受试者中PCVII感染存在的诊断方法。 衍生自病毒基因组的多核苷酸可用作诊断引物和探针。

公开(公告)号：US07180702B2

公开(公告)日：2007-02-20

申请号：US10795449

申请日：2004-03-09

Applicant: John Ellis ,  John A. Barkley ,  John D. Miller

Inventor： John Ellis ,  John A. Barkley ,  John D. Miller

IPC: G11B15/675

CPC classification number: G11B15/685

Abstract: A data cartridge handling apparatus comprises a ring-shaped carousel (40) rotatably mounted within a housing (22). Cartridge-accommodating cells (52) are angularly arranged about the carousel between an inner periphery (48) and an outer periphery (50) of the carousel. A transducing drive (70) is mounted within the housing and outside the outer periphery. A motor (60) rotates the carousel to facilitate selective alignment of a selected cell (52S) with the drive (70) along a radial dimension (106) of the carousel. A picker (100, 200) is mounted within the housing at a point within the inner periphery of the carousel (40). The picker (100, 200) has a picker arm (104, 204). A distal end of the picker arm has a gripper (110, 210) which selectively engages and disengages a data cartridge (72). The picker arm linearly translates in the radial dimension for the purpose of moving an engaged data cartridge from the selected cell (52S) to a loading position of the drive (70), and conversely for unloading a data cartridge from the drive and withdrawing the same into the selected cell. The gripper comprises a thumb (112, 230). One of the gripper and the thumb is pivotally connected to the picker arm to allow the thumb to selective engage and disengage a feature (160) on the data cartridge. A trip member (150, 250) is mounted in the housing between the outer periphery of the carousel and the drive for actuating pivoting of the gripper, and thereby actuating the selective disengagement of the picker thumb with the feature on the data cartridge for loading of the data cartridge into the drive.

Abstract translation: 数据盒式处理装置包括可旋转地安装在壳体（22）内的环形转盘（40）。 墨盒容纳单元（52）围绕转盘在转盘的内周（48）和外周（50）之间成角度地布置。 转换驱动器（70）安装在壳体内并在外周边外部。 马达（60）旋转圆盘传送带以便于选择的单元（52S）沿着圆盘传送带的径向尺寸（106）与驱动器（70）的选择性对准。 拾取器（100,200）安装在壳体内的转盘（40）的内周边内的点处。 拾取器（100,200）具有拾取臂（104,204）。 拾取臂的远端具有选择性地接合和脱离数据盒（72）的夹持器（110,210）。 拾取器臂在径向尺寸上线性地平移以便将所接合的数据盒从所选择的单元（52S）移动到驱动器（70）的装载位置，并且相反地用于从驱动器卸载数据盒，并且将 与所选单元格相同。 夹持器包括拇指（112,230）。 夹具和拇指中的一个枢转地连接到拾取臂，以允许拇指选择性地接合和脱离数据盒上的特征（160）。 跳闸构件（150,250）安装在旋转盘的外周边和驱动器之间的壳体中，用于致动夹持器的枢转，从而致动拾取器拇指与数据盒上的特征的选择性分离， 将数据磁带插入驱动器。

公开(公告)号：US20060248035A1

公开(公告)日：2006-11-02

申请号：US11116933

申请日：2005-04-27

Applicant: Sam Gendler ,  John Ellis ,  Steve Chang ,  Darren Davis

Inventor： Sam Gendler ,  John Ellis ,  Steve Chang ,  Darren Davis

IPC: G06F17/30

CPC classification number: G06F16/951

Abstract: A system and method of optimizing pay-for-placement advertising is disclosed. The disclosed method includes the selection of a metric for evaluating the performance of a pay-for-placement advertisement or “listing,” and predicting the performance of the listing relative to said metric using a particular search term at a plurality of positions on a plurality of search engines. The method further includes predicting the anticipated cost and effectiveness for each position, search engine combination, and the setting of new bids or retention of old bids for listings based on said predictions. The disclosed method includes the use of historical data regarding the effectiveness of a particular listing or search term to predict future performance at different listing positions or on different search engines or contextual advertising services. The party placing the advertising can then compare the effectiveness of a listing across different search engines or contextual advertising services in order to optimize its advertising campaigns.

Abstract translation: 披露了优化付费广告的系统和方法。 所公开的方法包括选择用于评估付费支付广告或“列出”的表现的度量，并且使用多个位置上的特定搜索项来预测相对于所述度量的列表的表现 的搜索引擎。 该方法还包括基于所述预测来预测每个职位，搜索引擎组合的预期成本和有效性，以及针对列表的新出价或保留旧出价的设置。 所公开的方法包括使用关于特定列表或搜索项的有效性的历史数据来预测在不同列表位置或不同搜索引擎或上下文广告服务的未来表现。 然后，放置广告的派对可以比较不同搜索引擎或内容相关广告服务的列表的有效性，以优化其广告活动。

公开(公告)号：US20060105654A1

公开(公告)日：2006-05-18

申请号：US10483902

申请日：2002-07-17

Applicant: John Ellis ,  Susan Bamford ,  Claire Balcomb

Inventor： John Ellis ,  Susan Bamford ,  Claire Balcomb

IPC: C08G6/02 ,  B32B27/04

CPC classification number: D06M15/53 ,  C08G65/007 ,  D06M2101/12 ,  D06M2200/11 ,  D06M2200/12 ,  D06M2200/45 ,  D06M2200/50 ,  Y10T442/25

Abstract: A polymer adapted for the Shrink resist treatment of textile materials imparting water, stain and/or oil repellency. The polymer includes a fluorinated polyether.

Abstract translation: 适合于收缩抗水性的聚合物，赋予水，染色和/或拒油性的纺织品。 聚合物包括氟化聚醚。

公开(公告)号：US20050058653A1

公开(公告)日：2005-03-17

申请号：US10780318

申请日：2004-02-17

Applicant: John Ellis ,  Gordon Allan ,  Brian Meehan ,  Edward Clark ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Charreyre ,  Gilles Chappuis ,  George Krakowka ,  Jean-Christophe Audonnet ,  Francis McNeilly

Inventor： John Ellis ,  Gordon Allan ,  Brian Meehan ,  Edward Clark ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Charreyre ,  Gilles Chappuis ,  George Krakowka ,  Jean-Christophe Audonnet ,  Francis McNeilly

IPC: A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  C07K14/01 ,  C12N7/00

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/5256 ,  A61K2039/53 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N7/00 ,  C12N2710/10343 ,  C12N2710/16743 ,  C12N2710/24043 ,  C12N2750/10022 ,  C12N2750/10034

Abstract: Porcine circovirus-2 (PCV-2) is a recently identified agent wherein the potential spectrum of PCV-2-associated disease has been expanded by evidence of vertical and sexual transmission and associated reproductive failure in swine populations. PCV-2 was isolated from a litter of aborted piglets from a farm experiencing late term abortions and stillbirths. Severe, diffuse myocarditis was present in one piglet associated with extensive immunohistochemical staining for PCV-2 antigen. Variable amounts of PCV-2 antigen were also present in liver, lung and kidney of multiple fetuses. Inoculation of female pigs with a composition including an immunogen from PCV-2 or an epitope of interest from such an immunogen or with a vector expressing such an immunogen or epitope of interest prior to breeding, such as within the first five weeks of life, or prior to the perinatal period, or repeatedly over a lifetime, or during pregnancy, such as between the 6th and 8th and/or the 10th and 13th weeks of gestation, can lower viral titer, prevent myocarditis, abortion and intrauterine infection associated with porcine circovirus-2. In addition, innoculation of male and/or female pigs with the aforementioned compositions can be carried out to prevent transmission of PCV-2 from male to female (or vice versa) during mating. Thus, the invention involves methods and compositions for preventing myocarditis, abortion and intrauterine infection associated with porcine circovirus-2.

Abstract translation: 猪圆环病毒-2（PCV-2）是最近确定的药物，其中PCV-2相关疾病的潜在谱已经通过垂直和性传播的证据以及猪群体相关的生殖失败而扩大。 从经历了晚期堕胎和死胎的农场的排卵仔猪中分离出PCV-2。 在与PCV-2抗原的广泛免疫组织化学染色相关的一只仔猪中存在严重的弥漫性心肌炎。 不同量的PCV-2抗原也存在于多个胎儿的肝，肺和肾中。 包括来自PCV-2的免疫原的组合物或来自这种免疫原的感兴趣的表位的组合物的雌性猪或在繁殖之前（例如在生命的前五周内）表达这种免疫原或感兴趣的表位的载体，或 在围产期，或一生以上，或怀孕期间，例如6〜8和/或10〜13周的妊娠期间，可以降低病毒滴度 ，预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染。 此外，可以进行具有上述组成的雄性和/或雌性猪的接种，以防止在交配期间PCV-2从雄性到雌性（或反之亦然）的传播。 因此，本发明涉及用于预防与猪圆环病毒-2相关的心肌炎，流产和子宫内感染的方法和组合物。

公开(公告)号：US06660272B2

公开(公告)日：2003-12-09

申请号：US09884514

申请日：2001-06-19

Applicant: Gordon Allan ,  Brian Meehan ,  Edward Clark ,  John Ellis ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly

Inventor： Gordon Allan ,  Brian Meehan ,  Edward Clark ,  John Ellis ,  Deborah Haines ,  Lori Hassard ,  John Harding ,  Catherine Elisabeth Charreyre ,  Gilles Emile Chappuis ,  Francis McNeilly

IPC: A61K3912

CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  A61K39/12 ,  A61K48/00 ,  A61K2039/51 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  C12N2710/10343 ,  C12N2710/16043 ,  C12N2710/24043 ,  C12N2750/10021 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/10043 ,  C12N2750/10063 ,  C12N2750/10064

Abstract: The invention relates to new porcine circovirus strains isolated from pulmonary or ganglionic samples obtained from farms affected by the post-weaning multisystemic wasting syndrome (PMWS). It relates to purified preparations of these strains, conventional attenuated or inactivated vaccines, recombinant live vaccines, plasmid vaccines and subunit vaccines, as well as reagents and diagnostic methods. It also relates to the DNA fragments which can be used for the production of subunits in an in vitro expression vector or as sequences to be integrated into a virus or plasmid type in vivo expression vector.

公开(公告)号：US5351433A

公开(公告)日：1994-10-04

申请号：US4891

申请日：1993-01-21

Applicant: John Ellis

Inventor： John Ellis

IPC: A01K85/16 ,  A01K85/00

CPC classification number: A01K85/16

Abstract: A fishing lure has a body with a replaceable bib mounted by releasable locking means within a slot at its forward end. The bib can thereby be replaced by a bib which provides different depth characteristics for the lure.

Abstract translation: 钓鱼诱饵有一个身体，一个可更换的围兜，其可拆卸的锁定装置在其前端的狭槽内安装。 因此，围兜可以由为诱惑提供不同深度特征的围兜来替代。

公开(公告)号：US5278266A

公开(公告)日：1994-01-11

申请号：US831578

申请日：1992-02-05

Applicant: Julian H. Braybrook ,  John Ellis

Inventor： Julian H. Braybrook ,  John Ellis

IPC: C04B26/04 ,  C04B28/28 ,  C08F2/44 ,  C08F30/02 ,  C08F8/12

CPC classification number: C08F30/02 ,  C04B28/28

Abstract: Poly(vinyl phosphonic acid) is synthesized by polymerizing vinyl phosphonyl dichloride in the presence of a cross-linker such as formaldehyde or 1,3-butadiene di-epoxide, with a free-radical initiator. The product can be reacted with aluminosilicate glass to form an improved cement.

Abstract translation: 聚（乙烯基膦酸）通过在交联剂例如甲醛或1,3-丁二烯二环氧化物存在下与自由基引发剂聚合而合成乙烯基膦酰氯。 该产物可与铝硅酸盐玻璃反应以形成改进的水泥。

公开(公告)号：US5195752A

公开(公告)日：1993-03-23

申请号：US779904

申请日：1991-10-21

Applicant: Gary L. Reeves ,  John Ellis

Inventor： Gary L. Reeves ,  John Ellis

IPC: F41G3/26 ,  F41J5/04

CPC classification number: F41G3/26 ,  F41J5/04

Abstract: Disclosed is an impact-responsive vest having a piezoelectric layer sandwiched between other layers and connected by wire leads to a control module. The control module includes a programmable read-only memory having parameters identifying, through the amplitude of a signal impact, forces produced by paint ball impacts which are compared with impact signals from the vest. When a match is found, the compare circuit sends a signal to an audible alarm to alert the wearer that he or she has been hit by a paint ball. The control module is compact and is worn by the vest-user. Also disclosed is a remote reset module to provide a reset signal to the control module once the alarm has been activated.

Abstract translation: 公开了一种抗冲击背心，其具有夹在其它层之间的压电层，并通过导线连接到控制模块。 控制模块包括可编程只读存储器，其具有通过信号冲击的幅度来鉴定与油漆球撞击产生的力相比较的参数，其与来自背心的冲击信号相比较。 当发现匹配时，比较电路将信号发送到声音报警器，以警告佩戴者他或她被油漆球击中。 控制模块紧凑，由背心使用者佩戴。 还公开了一种远程复位模块，用于在触发报警器后向控制模块提供复位信号。

公开(公告)号：US4399911A

公开(公告)日：1983-08-23

申请号：US277345

申请日：1981-06-25

Applicant: John M. Murphy ,  Robert H. Spensley ,  John Ellis

Inventor： John M. Murphy ,  Robert H. Spensley ,  John Ellis

IPC: E21D20/02 ,  F16B13/14 ,  B65D25/08

CPC classification number: E21D20/026 ,  F16B13/143

Abstract: An anchoring cartridge suitable for use in anchoring a reinforcing or fixing element such as an anchor bolt in a borehole in a substrate contains a particulate liquid-settable solid component, such as a hydraulic cement, within a frangible liquid-impermeable casing. Through the solid component passes a discontinuous tube at least one end of which is located at one end of the cartridge so as to be in communication with the exterior. To activate the cartridge, it is placed within an activating liquid, such as water, which flows into the cartridge via the discontinuous tube and thus into contact with the solid component from within the cartridge over substantially its whole length, so that after a relatively short time, i.e. a few minutes, the activated cartridge can be positioned for use in a borehole. This discontinuous tube regulates the flow of activating liquid into the solid component and serves to ensure the formation of a self-setting grouting composition of substantially uniform strength when the cartridge is used in anchor bolting.

Abstract translation: 适于用于将诸如锚定螺栓的加强或固定元件锚定在基底中的钻孔中的锚定筒在易碎的液体不可渗透的外壳内容纳有诸如水硬性水泥的颗粒状液体可固化的固体组分。 通过固体组分通过不连续管，其中至少一端位于药筒的一端以便与外部连通。 为了激活墨盒，将其放置在诸如水的激活液体中，其通过不连续的管流入墨盒中，并且因此在其基本上整个长度上与墨盒内的固体组分接触，使得在较短的时间 时间，即几分钟，激活的墨盒可以定位在钻孔中使用。 这种不连续的管调节活化液体进入固体组分的流动，并且用于确保当将该药筒用于锚栓时形成基本上均匀强度的自固化灌浆组合物。