公开(公告)号：US20110074410A1

公开(公告)日：2011-03-31

申请号：US12585871

申请日：2009-09-28

申请人： Ralf Ladebeck ,  Johannes Pauli ,  Charles C. Watson

发明人： Ralf Ladebeck ,  Johannes Pauli ,  Charles C. Watson

IPC分类号： G01V3/00

CPC分类号： G01R33/481 ,  G01R33/58 ,  G01T1/1603 ,  G01T1/1648

摘要： A method and a system are disclosed for calibrating an emission tomography subsystem in a combined MR (magnetic resonance) and emission tomography imaging system. In at least one embodiment, the method includes providing a phantom that is configured such that the phantom is visible on a MR image, providing an attenuation map of the phantom, wherein the attenuation map includes an attenuation of the phantom, obtaining the MR image of the phantom, obtaining a position of the phantom from the MR image, mapping the attenuation map with the position of the phantom, and calibrating the emission tomography subsystem using the attenuation map mapped with the position of the phantom.

摘要翻译： 公开了用于校准组合MR（磁共振）和发射断层摄影成像系统中的发射断层扫描子系统的方法和系统。 在至少一个实施例中，该方法包括提供被配置为使得该幻像在MR图像上可见的假体，提供该体模的衰减图，其中该衰减图包括该体模的衰减，获得该虚像的MR图像 幻影，从MR图像获得体模的位置，将衰减图与幻影的位置对准，并使用映射与体模位置的衰减图校准发射断层摄影子系统。

公开(公告)号：US07835781B2

公开(公告)日：2010-11-16

申请号：US11882693

申请日：2007-08-03

申请人： Ralf Ladebeck ,  Diana Martin ,  Norbert Rietsch

发明人： Ralf Ladebeck ,  Diana Martin ,  Norbert Rietsch

IPC分类号： A61B5/05 ,  A61B6/00

CPC分类号： G01R33/481 ,  A61B6/037 ,  G01T1/1603

摘要： A device is disclosed for superposed MRI and PET imaging and includes an MRI tube that has a first field of view along its longitudinal direction, and a multiplicity of PET detection units arranged opposite one another in pairs about the longitudinal direction. In at least one embodiment the many PET detection units define a second field of view along the longitudinal direction, and their arrangement density along the longitudinal direction is optimized such that the second field of view substantially corresponds to the first field of view.

摘要翻译： 公开了一种用于重叠的MRI和PET成像的装置，并且包括沿着其纵向方向具有第一视场的MRI管和多个相对于纵向方向成对布置的PET检测单元。 在至少一个实施例中，许多PET检测单元沿着纵向方向限定第二视场，并且优化其沿着纵向方向的排列密度，使得第二视场基本上对应于第一视场。

公开(公告)号：US20100278406A1

公开(公告)日：2010-11-04

申请号：US12626127

申请日：2009-11-25

申请人： Gaspar Delso ,  Ralf Ladebeck ,  Axel Martinez-Mõller ,  Sibylle Ziegler

发明人： Gaspar Delso ,  Ralf Ladebeck ,  Axel Martinez-Mõller ,  Sibylle Ziegler

IPC分类号： G06K9/00

CPC分类号： A61B6/03 ,  G01R33/481 ,  G06T11/005 ,  G06T2211/432

摘要： A method and an system are disclosed for reconstructing an emission tomography image in a combined MR (magnetic resonance) and emission tomography imaging system. In at least one embodiment, the method includes obtaining an MR image of a subject, the subject being clipped in the MR image; obtaining raw emission tomography scan data of the subject; determining a missing part of the subject clipped in the MR image; using information of the MR image and the determined missing part to obtain a final attenuation model of the subject; and reconstructing the emission tomography image using the raw data and the final attenuation model.

摘要翻译： 公开了用于在组合MR（磁共振）和发射断层摄影成像系统中重建发射断层摄影图像的方法和系统。 在至少一个实施例中，该方法包括：获得被摄体的MR图像，将被摄体剪切在MR图像中; 获得受试者的原始放射断层扫描数据; 确定在MR图像中剪切的被摄​​体的缺失部分; 使用MR图像和确定的缺失部分的信息来获得对象的最终衰减模型; 并使用原始数据和最终衰减模型重建发射断层摄影图像。

公开(公告)号：US20100134108A1

公开(公告)日：2010-06-03

申请号：US12566837

申请日：2009-09-25

申请人： Sascha Fath ,  Ralf Ladebeck

发明人： Sascha Fath ,  Ralf Ladebeck

IPC分类号： G01R33/44

CPC分类号： G01R33/385 ,  G01R33/481

摘要： In a method for designing a gradient coil composed of multiple sub-coils, parameters representing the structure of the gradient coil are varied, and the variation that produces an optimized electrical field generated by the gradient coil is determined. The final design of the gradient coil embodies those parameters that produced the optimal electrical field. In a method for manufacturing a gradient coil, the gradient coil is manufactured according to the final design. A gradient coil manufactured according to the invention has a gradient conductor configuration that optimizes the electrical field generated by the gradient coil. A magnetic resonance apparatus, and a combined positron emission tomography/magnetic resonance apparatus, embodies such a gradient coil.

摘要翻译： 在用于设计由多个子线圈组成的梯度线圈的方法中，改变表示梯度线圈的结构的参数，并且确定由梯度线圈产生的优化电场的变化。 梯度线圈的最终设计体现了产生最佳电场的那些参数。 在制造梯度线圈的方法中，根据最终设计制造梯度线圈。 根据本发明制造的梯度线圈具有优化梯度线圈产生的电场的梯度导体配置。 磁共振装置和组合的正电子发射断层摄影/磁共振装置体现了这种梯度线圈。

公开(公告)号：US20100074501A1

公开(公告)日：2010-03-25

申请号：US12564685

申请日：2009-09-22

申请人： Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

发明人： Ralf Ladebeck ,  Christian J. Michel ,  Charles C. Watson

IPC分类号： G06K9/00 ,  G06F7/60

CPC分类号： G01R33/481

摘要： A method for co-registering attenuation data of MR coils in a MR/PET imaging system with PET emission data includes computing a likelihood of PET emission data on a grid in a parameter space based on an algorithm, wherein the algorithm defines L(λ, μbody, μcoils{p}) as a log-likelihood of measured PET data, where λ is an emitter distribution (image), μbody is a known linear attenuation coefficient (LAC) distribution of the body from MRI, μcoils is a linear attenuation coefficient map of MRI coils, and {p} is a set of parameters governing the position of each coil, wherein if μcoils is assumed, then λ can be reconstructed and forward projected and L can be computed. The method includes adjusting the estimated position of the MR coils to maximize the likelihood of emission data based on the computed L.

摘要翻译： 在具有PET发射数据的MR / PET成像系统中共同记录MR线圈的衰减数据的方法包括基于算法计算参数空间中的网格上的PET发射数据的可能性，其中所述算法定义L（λ， μbody，μcoils{p}）作为测量PET数据的对数似然度，其中λ是发射体分布（图像），μbody是来自MRI的身体的已知线性衰减系数（LAC）分布，μ线圈是线性衰减系数 MRI线圈图，{p}是控制每个线圈位置的一组参数，其中如果假设为μcoils，则可以重建λ并且向前投影，并且可以计算L。 该方法包括调整MR线圈的估计位置，以使基于计算出的L的发射数据的可能性最大化。

公开(公告)号：US20090278049A1

公开(公告)日：2009-11-12

申请号：US12453329

申请日：2009-05-07

申请人： Ralf Ladebeck

发明人： Ralf Ladebeck

IPC分类号： G01T1/20 ,  G01V3/00

CPC分类号： G01R33/481 ,  A61B5/055 ,  A61B6/037 ,  A61B6/4417 ,  A61B6/5258 ,  A61B6/583

摘要： A method is disclosed for producing an attenuation map for a component of an MR/PET system. In at least one embodiment, the method includes ascertaining attenuation values of the component, producing a basic map from the attenuation values, ascertaining a position of the component relative to an examination volume of the MR/PET system, and producing the attenuation map by correcting the basic map using the ascertained position. This enables the actual position of the components to be taken into account in the attenuation correction.

摘要翻译： 公开了一种用于制造MR / PET系统的部件的衰减图的方法。 在至少一个实施例中，该方法包括确定组件的衰减值，从衰减值产生基本图，确定组件相对于MR / PET系统的检查体积的位置，以及通过校正来产生衰减图 使用确定位置的基本地图。 这使得能够在衰减校正中考虑到组件的实际位置。

公开(公告)号：US20090041318A1

公开(公告)日：2009-02-12

申请号：US12219613

申请日：2008-07-24

申请人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

发明人： Thorsten Feiweier ,  Ralf Ladebeck ,  Diana Martin ,  Hartwig Newiger ,  Josef Pfeuffer ,  Michael Szimtenings ,  Harald Werthner

IPC分类号： G01R33/56 ,  G01R33/54

CPC分类号： A61B6/032 ,  A61B5/11 ,  A61B5/7285 ,  A61B6/037 ,  A61B6/541 ,  A61B8/00 ,  A61B8/4416 ,  G06F19/00

摘要： A method is disclosed for recording measured data of a patient while taking account of movement operations by way of a medical device that is designed both for recording movement-related measured data, in particular measured data of high temporal resolution and/or measured data that can be interpolated with regard to movement operations, with the aid of an imaging method and/or by means of at least one sensor element, and also for recording nuclear medicine measured data, in particular of lower temporal resolution. In at least one embodiment, the method includes recording nuclear medicine measured data with the aid of the medical device; simultaneously recording movement-related measured data with the aid of the medical device; determining at least one item of movement information relating to at least one movement operation of the patient and/or in the body of the patient by evaluating at least a portion of the recorded measured data of high temporal resolution on the part of a computing device of the medical device; and adapting at least one item of attenuation correction information available for the computing device and serving for reconstructing the nuclear medicine measured data, doing so as a function of the at least one determined item of movement information.

摘要翻译： 公开了一种用于记录患者的测量数据的方法，同时考虑到通过设计用于记录运动相关测量数据的医疗设备，特别是高时间分辨率的测量数据和/或可测量数据的测量数据， 借助于成像方法和/或通过至少一个传感器元件，以及用于记录核医学测量数据，特别是用于记录较低时间分辨率的内插关于移动操作。 在至少一个实施例中，该方法包括借助医疗装置记录核医学测量数据; 借助医疗设备同时记录运动相关测量数据; 通过在计算设备的一部分上评估所记录的高时间分辨率测量数据的至少一部分来确定与患者的至少一个移动操作和/或患者身体有关的至少一个移动信息项 医疗器械; 以及修改可用于所述计算设备的至少一项衰减校正信息，并且用于重构所述核医学测量数据，作为所述至少一个确定的运动信息项的函数。

公开(公告)号：US07327138B2

公开(公告)日：2008-02-05

申请号：US11222876

申请日：2005-09-09

申请人： Robert Krieg ,  Ralf Ladebeck ,  Oliver Schreck

发明人： Robert Krieg ,  Ralf Ladebeck ,  Oliver Schreck

IPC分类号： G01V3/00

CPC分类号： A61B5/055 ,  A61B6/03 ,  A61B6/5247 ,  G06F19/00

摘要： A nuclear-medical image is generated from a nuclear-medical data set that can be acquired with a dual modality tomography apparatus, which has both a scanner for acquisition of magnetic resonance images and a scanner for acquisition of nuclear-medical data sets within a common acquisition volume. A nuclear-medical data set and an MR image are thereby acquired, and a nuclear-medical magnetic resonance atlas is provided with a reference MR data set of the region of a reference patient to be imaged and a corresponding correction data set. A transformation that maps the reference MR data set to the MR image is generated and applied to the correction data set to generate a transformed correction data set that is registered with the nuclear-medical data set. The corrected nuclear-medical image is subsequently calculated from the transformed correction data set and the nuclear-medical data set.

摘要翻译： 核医学图像由可以用双模态断层摄影装置获取的核医学数据集产生，该双模态断层摄影装置既具有用于获取磁共振图像的扫描仪和用于获取共同体内的核医学数据集的扫描仪 收购量。 由此获取核医学数据集和MR图像，并且向核医学磁共振图谱提供要成像的参考患者的区域的参考MR数据集和相应的校正数据集。 产生将参考MR数据集映射到MR图像的变换，并将其应用于校正数据集，以生成被登记在核医学数据集中的经变换的校正数据集。 随后从经变换的校正数据集和核医学数据集计算校正的核医学图像。

公开(公告)号：US20080027308A1

公开(公告)日：2008-01-31

申请号：US11808655

申请日：2007-06-12

申请人： Ralf Ladebeck

发明人： Ralf Ladebeck

IPC分类号： A61B5/055

CPC分类号： G01R33/28 ,  G01R33/481 ,  G01T1/1603

摘要： A sensor device, in particular a PET detector, for operation in the time-varying magnetic field of a magnetic resonance tomograph. In at least one embodiment, a sensor circuit is for generating a sensor signal, as well as an induction circuit in which a compensation signal is induced. These signals are combined with one another so as to compensate for noise signals in the sensor signal, which are induced in the sensor circuit by the time-varying magnetic field. The invention furthermore concerns a method of compensating for such noise signals.

摘要翻译： 用于在磁共振断层摄影机的时变磁场中操作的传感器装置，特别是PET检测器。 在至少一个实施例中，传感器电路用于产生传感器信号，以及其中引入补偿信号的感应电路。 这些信号彼此组合，以补偿传感器信号中由时变磁场感生的传感器电路中的噪声信号。 本发明还涉及一种补偿这种噪声信号的方法。