Medicinal compositions for treatment of atrial fibrillation
    91.
    发明授权
    Medicinal compositions for treatment of atrial fibrillation 失效
    用于治疗房颤的药物组合物

    公开(公告)号:US06506745B1

    公开(公告)日:2003-01-14

    申请号:US09869428

    申请日:2001-06-28

    IPC分类号: A61K3155

    CPC分类号: C07D417/06

    摘要: The present invention relates to a medical composition for atrial fibrillation treatment, comprising a compound represented by the following formula [I]: Formula [I] [wherein R1 represents a hydrogen atom or lower alkoxy group; R2 represents a hydrogen atom, lower alkoxy group or phenyl group (wherein the phenyl group may be substituted with 1 to 3 substituents selected from a group consisting of a hydroxides group and a lower alkoxy group), (wherein R3 represents an acyl group); X represents —CO— or —CH2—, and n represents an integer of 1 or 2.] The present invention also relates to a method of treating atrial fibrillation using said compound, and to the use of said compound for producing a medicine for atrial fibrillation treatment or salts thereof or prodrugs thereof.

    摘要翻译: 本发明涉及一种用于心房颤动治疗的医药组合物,其包含由下式[I]表示的化合物:式[I] [其中R 1表示氢原子或低级烷氧基; R2表示氢原子,低级烷氧基或苯基(其中苯基可被1〜3个选自氢氧基和低级烷氧基的取代基取代),(其中R3表示酰基)。 X表示-CO-或-CH2-,n表示1或2的整数。]本发明还涉及使用所述化合物治疗心房颤动的方法,以及所述化合物在制备用于心房的药物中的用途 原纤维化处理或其盐或其前药。

    Electrophotographic toner and method of manufacturing same
    92.
    发明授权
    Electrophotographic toner and method of manufacturing same 失效
    电子照相墨粉及其制造方法

    公开(公告)号:US5981129A

    公开(公告)日:1999-11-09

    申请号:US25113

    申请日:1998-02-17

    IPC分类号: G03G9/08 G03G9/093

    摘要: An electrophotographic toner is made up of toner particles composed of irregularly-shaped core particles made chiefly of binder resin, and surface-modifying fine particles which are first dispersed over and attached to the surface of the core particles, and then affixed or formed into a film thereon. The BET specific surface area, based on N.sub.2 adsorption, of the toner particles is less than 0.64 times the BET specific surface area of the core particles and surface-modifying fine particles combined together. Further, this value is 1.07 times the BET specific surface area of hypothetical toner particles which are perfect spheres. Consequently, the toner is not prone to problems such as filming, toner scattering, and fogging which are caused by peeling, separation, etc. of the surface-modifying fine particles, nor to poor cleaning due to spherical toner particles. Further, since the toner is manufactured with a quantitative grasp of the state of modification of the surface of the core particles by the surface-modifying fine particles, it is a toner in a stable state.

    摘要翻译: 电子照相调色剂由主要由粘合剂树脂制成的不规则形状的核心颗粒和首先分散在核颗粒表面上并附着在核颗粒表面上的表面改性微粒组成的调色剂颗粒组成,然后固定或形成为 膜上。 调色剂颗粒的基于N2吸附的BET比表面积小于核心颗粒的BET比表面积和结合在一起的表面改性微粒的0.64倍。 此外,该值是完美球体的假想调色剂颗粒的BET比表面积的1.07倍。 因此,调色剂不容易出现由表面改性微粒的剥离,分离等引起的成膜,调色剂飞散和起雾等问题,也不会由于球形调色剂颗粒而导致不良清洁。 此外,由于调色剂通过表面改性细颗粒对芯颗粒的表面的修饰状态的定量掌握来制造,所以它是调色剂处于稳定状态。

    Preferential recording system for a facsimile apparatus
    93.
    发明授权
    Preferential recording system for a facsimile apparatus 失效
    传真机的优惠录音系统

    公开(公告)号:US5608540A

    公开(公告)日:1997-03-04

    申请号:US303876

    申请日:1994-09-09

    申请人: Satoshi Ogawa

    发明人: Satoshi Ogawa

    摘要: In a preferential recording system provided in a transmission unit and a reception unit of a facsimile apparatus, the preferential recording system includes: a priority/time setting unit provided in the transmission unit for setting priority of recording desired time of recording at the reception side into the telegram message to be transmitted from the transmission unit of the transmission side to the reception unit of the reception side; a priority/time decision unit provided in the reception unit for determining the priority of the recording and/or the desired time of the recording set into the telegram message; a priority/time memory also provided in the reception unit for storing the priority of the recording and the actual time of the recording for every telegram message; and a time counting unit also provided in the reception unit for imparting present time and a setting time of recording to the priority/time decision unit.

    摘要翻译: 在提供在传真单元和传真设备的接收单元中的优选记录系统中,优先记录系统包括:优先/时间设置单元,设置在发送单元中,用于将在接收侧记录期望的记录时间的优先级设置为 要从发送侧的发送单元发送到接收侧的接收单元的电报消息; 在所述接收单元中设置的优先/时间判定单元,用于确定所述记录的优先级和/或所述记录集合到所述电报消息中的期望时间; 在接收单元中还设置有用于存储每个电报消息的记录的优先级和实际记录时间的优先/时间存储器; 以及还设置在接收单元中的时间计数单元,用于将当前时间和设置时间记录到优先/时间决定单元。

    Facsimile apparatus
    95.
    发明授权
    Facsimile apparatus 失效
    传真机

    公开(公告)号:US4646160A

    公开(公告)日:1987-02-24

    申请号:US598334

    申请日:1984-03-14

    IPC分类号: H04N1/32

    摘要: A facsimile apparatus for transmitting/receiving image data has a first memory for storing image data of one or more pages, a second memory for storing external apparatus number and time data, and an automatic send control for comparing the time data stored in the second memory with a time signal from a clock, and, upon detecting a coincidence thereof, for supplying the external apparatus number stored in the second memory to a network control to cause an automatic dialing thereof to connect a line with the external apparatus, so that image data is transmitted to or received from the external apparatus. The user of each facsimile apparatus can set or modify polling reception originating terminals, repeating destinations, polling/multi-address calling destinations or the like. The facsimile apparatus is convenient for a user who desires to perform facsimile transmission at a desired time.

    摘要翻译: PCT No.PCT / JP83 / 00281 Sec。 371日期1984年3月14日 102(e)日期1984年3月14日PCT提交1983年8月30日PCT公布。 出版物WO84 / 01074 一种用于发送/接收图像数据的传真装置具有用于存储一个或多个页面的图像数据的第一存储器,用于存储外部设备编号和时间数据的第二存储器,以及用于比较 存储在第二存储器中的时间数据具有来自时钟的时间信号,并且在检测到其一致时,将存储在第二存储器中的外部设备号码提供给网络控制器,以使其自动拨号将线路与 外部设备,使得图像数据被发送到外部设备或从外部设备接收。 每个传真装置的用户可以设置或修改轮询接收始发终端,重复目的地,轮询/多地址呼叫目的地等。 该传真装置对于希望在期望的时间执行传真传输的用户是方便的。

    Toner and developer
    98.
    发明授权
    Toner and developer 有权
    墨粉和开发商

    公开(公告)号:US09316938B2

    公开(公告)日:2016-04-19

    申请号:US14359429

    申请日:2012-10-17

    IPC分类号: G03G9/087 G03G9/08

    摘要: A toner including a non-crystalline polyester resin and a crystalline polyester resin, wherein a tetrahydrofuran soluble component of the non-crystalline polyester resin has a weight-average molecular weight of 3,000 to 8,000 measured by gel permeation chromatography, and wherein the toner has a glass transition temperature A before an extraction process of the toner with methanol and a glass transition temperature B after the extraction process of the toner with methanol, and a difference between A and B (B−A) is 2.0° C. or less.

    摘要翻译: 包含非结晶性聚酯树脂和结晶性聚酯树脂的调色剂,其中所述非结晶性聚酯树脂的四氢呋喃可溶成分的重均分子量通过凝胶渗透色谱法测定为3,000〜8,000,并且其中所述调色剂具有 在甲醇萃取过程之前用甲醇萃取过程中的玻璃化转变温度A和玻璃化转变温度B之间,A和B(B-A)之间的差异为2.0℃或更低。

    Electron beam sterilization equipment for containers that uses revolving transport device
    99.
    发明授权
    Electron beam sterilization equipment for containers that uses revolving transport device 有权
    使用旋转运输装置的容器的电子束灭菌设备

    公开(公告)号:US09161999B2

    公开(公告)日:2015-10-20

    申请号:US14351182

    申请日:2012-10-15

    摘要: Electron beam sterilization equipment includes an outer-surface sterilization zone Z2 for sterilizing the outer surface of a container B by emitting electron beams when the container B is transported along circular paths L1 and L2; and an inner-surface sterilization zone Z3 for sterilizing the inner surface of the container B. An electron beam irradiator E1 is located near the upstream side of a 1-2 joint J1-2 of the circular paths L1 and L2 disposed in the outer-surface sterilization zone Z2, and a electron beam irradiator E2 is located near the downstream side of the joint. Thus, the electron beam irradiator E1 and the electron beam irradiator E2 are brought close to each other so as to sequentially sterilize the one half outer surfaces and the other half outer surface of the container B.

    摘要翻译: 电子束消毒设备包括一个外表面灭菌区Z2,用于当容器B沿着圆周路径L1和L2传送时,通过发射电子束来对容器B的外表面进行灭菌; 以及用于对容器B的内表面进行灭菌的内表面杀菌区域Z3。电子束照射器E1位于外围设置的圆形路径L1和L2的1-2关节J1-2的上游侧附近, 表面灭菌区Z2和电子束照射器E2位于接头的下游侧附近。 因此,电子束照射器E1和电子束照射器E2彼此靠近,以便对容器B的一个半外表面和另一个半外表面进行消毒。

    Labeled protein and method for obtaining the same
    100.
    发明授权
    Labeled protein and method for obtaining the same 有权
    标记蛋白质及其获得方法

    公开(公告)号:US08993715B2

    公开(公告)日:2015-03-31

    申请号:US12830244

    申请日:2010-07-02

    IPC分类号: C07K7/00 C07K1/13 C07K16/32

    摘要: It is an object of the present invention to obtain a labeled protein, and specifically, to separate a labeled protein and the same unlabeled protein. There is provided a labeled protein including: a protein to be labeled having a target protein, at least one or more affinity interaction domains for binding to an affinity support, and at least one or more labeling sites; and a labeling reagent binding to at least one of the labeling sites; wherein the affinity of the labeled protein for the affinity support is difference from that of the protein to be labeled for the affinity support.

    摘要翻译: 本发明的目的是获得标记的蛋白质,特别是分离标记的蛋白质和相同的未标记的蛋白质。 提供了标记的蛋白质,其包括:待标记的蛋白质,其具有靶蛋白质,至少一个或多个与亲和载体结合的亲和作用结构域,以及至少一个或多个标记位点; 和与至少一个标记位点结合的标记试剂; 其中所述标记的蛋白质对所述亲和载体的亲和力与所述亲和载体的待标记蛋白质的亲和力不同。