公开(公告)号：US20160012636A1

公开(公告)日：2016-01-14

申请号：US14789413

申请日：2015-07-01

申请人： Günter Lauritsch ,  Thomas Redel ,  Christopher Rohkohl ,  Michael Scheuering

发明人： Günter Lauritsch ,  Thomas Redel ,  Christopher Rohkohl ,  Michael Scheuering

IPC分类号： G06T17/10 ,  A61B6/03 ,  A61B6/00 ,  G06T11/60

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/4441 ,  A61B6/5205 ,  A61B6/5288 ,  A61B6/5294 ,  G06T11/60 ,  G06T17/00 ,  G06T2200/04 ,  G06T2210/41

摘要： A three-dimensional model dataset of a blood vessel system of a patient including at least one the vessel system is determined from a number of projection images, which have been recorded from different recording angles, of the blood vessel system The projection images are divided up into image areas each containing at least one pixel. A feature vector is determined for each of the image areas. Classification information, which describes how the respective image area belongs or does not belong to a vessel segment of the blood vessel system defined in accordance with anatomical specification data, is defined for each of the image areas by applying a classification function to the feature vector assigned to the image area. The classification function has been trained by training data records annotated with classification information obtained from at least one person other than the patient. The blood vessel system in the projection images is segmented by grouping image areas with the same classification information. The three-dimensional model dataset is calculated as a function of the segmented projection images and the classification information.

摘要翻译： 包括至少一个血管系统的患者的血管系统的三维模型数据集是从血管系统的不同记录角度记录的多个投影图像确定的。将投影图像分割 到每个包含至少一个像素的图像区域中。 为每个图像区域确定特征向量。 通过对分配的特征矢量应用分类函数，对每个图像区域分别描述各个图像区域属于或不属于根据解剖规范数据定义的血管系统的血管段的分类信息 到图像区域。 分类功能已经通过训练用从患者以外的至少一个人获得的分类信息注释的数据记录来训练。 投影图像中的血管系统通过对具有相同分类信息的图像区域进行分组。 三维模型数据集被计算为分段投影图像和分类信息的函数。

公开(公告)号：US08948475B2

公开(公告)日：2015-02-03

申请号：US12825785

申请日：2010-06-29

申请人： Martin Ostermeier ,  Marcus Pfister ,  Thomas Redel

发明人： Martin Ostermeier ,  Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00 ,  A61B6/00 ,  G06T11/00

CPC分类号： A61B6/504 ,  A61B6/463 ,  A61B6/503 ,  A61B6/5235 ,  G06T11/001

摘要： A method for computing a color-coded analysis image of an examination area of an examination object from a temporal sequence of fluoroscopic images of the examination area comprising a vascular system containing arteries and/or veins is provided. An acquisition time instant has been assigned to each of the fluoroscopic images representing a given distribution of a material embolizing some of the vascular system. The fluoroscopic image spatially corresponds to an analysis image pixel by pixel. A computer receives the fluoroscopic images with a color attribute assigned to each pixel of the analysis image at an image point and a time instant. If a pixel differs from a pixel at a preceding time instant, the color attribute assumes a color attribute of the time instant and the difference. If a pixel corresponds to a background color of the analysis image, the color attribute assumes a background color.

摘要翻译： 提供了一种用于从包括含有动脉和/或静脉的血管系统的检查区域的荧光透视图像的时间序列计算检查对象的检查区域的颜色编码分析图像的方法。 已经将采集时刻分配给表示栓塞一些血管系统的材料的给定分布的每个透视图。 透视图像在空间上对应于逐像素的分析图像。 计算机接收在图像点和时刻分配给分析图像的每个像素的颜色属性的透视图像。 如果像素与前一时刻的像素不同，则颜色属性假定时刻的颜色属性和差异。 如果像素对应于分析图像的背景颜色，则颜色属性假定为背景颜色。

公开(公告)号：US20150018670A1

公开(公告)日：2015-01-15

申请号：US14013152

申请日：2013-08-29

申请人： Thomas Hartkens ,  Thomas Redel

发明人： Thomas Hartkens ,  Thomas Redel

IPC分类号： A61B6/12 ,  A61B6/00

CPC分类号： A61B6/12 ,  A61B6/486 ,  A61B6/488 ,  A61B6/5217 ,  A61B6/5247 ,  A61B34/20 ,  A61B34/30 ,  A61B2090/376 ,  A61B2090/3966

摘要： An interventional medical diagnosis and/or therapy system is provided. The system provides an interventional imaging system and method which allows for an intervention, to be conducted in accordance with an intervention plan, to be supported and monitored by ongoing imaging, in particular radioscopy, with which, at the same time the effort in calibration and registration is kept low, and which functions without an additional location system. The interventional imaging system includes an imaging device to record intervention data of a body, at least two position markings, capable of being recorded with the imaging device, for the marking of an intervention instrument, a display apparatus to reproduce recorded intervention data and position markings, a navigation facility connected to the display apparatus to load pre-intervention data of the body, in which an intervention location of the body is contained, and for the mutual registration of the pre-intervention data with the intervention data.

摘要翻译： 提供介入性医学诊断和/或治疗系统。 该系统提供介入成像系统和方法，其允许根据干预计划进行干预，以通过正在进行的成像，特别是放射检查来支持和监测，同时在校准和 注册保持较低，哪些功能没有额外的位置系统。 介入成像系统包括成像装置，用于记录身体的干预数据，能够与成像装置一起记录的至少两个位置标记，用于干预仪器的标记，显示装置，以再现记录的干预数据和位置标记 连接到显示装置的导航设备，以加载身体的干预前的数据，其中包含身体的介入位置，以及干预前数据与干预数据的相互注册。

公开(公告)号：US08706196B2

公开(公告)日：2014-04-22

申请号：US13208451

申请日：2011-08-12

申请人： Thomas Redel

发明人： Thomas Redel

IPC分类号： A61B5/05 ,  A61B5/02 ,  A61B5/00 ,  G06K9/00 ,  G06K9/20

CPC分类号： A61B6/4441 ,  A61B6/4458 ,  A61B6/481 ,  A61B6/504 ,  A61B6/507

摘要： A method for simulating a blood flow in a vascular segment of a patient is proposed. A 3D image dataset of an examination region is recorded by a radiographic diagnostic device for generating a 3D vascular model. Contrast agent propagation in the examination region is captured by a dynamic 2D angiography method for generating a real 2D angiography recording. A CFD simulation of the blood flow is performed in the 3D vascular model based on a blood flow parameter for generating a virtual 2D angiography recording. A degree of correspondence between the real and the virtual 2D angiography recordings is determined from identical angulation and adjusted recording geometry of the patient and compared with predefinable tolerance values. The CFD simulation is iteratively optimized while changing the blood flow parameter as a function of the comparison. The degree of correspondence is outputted when the optimum CFD simulation is achieved.

摘要翻译： 提出了一种模拟患者血管段血流的方法。 检查区域的3D图像数据集由用于产生3D血管模型的射线照相诊断装置记录。 通过用于产生真实2D血管造影记录的动态2D血管造影方法捕获检查区域中的造影剂传播。 基于用于产生虚拟2D血管造影记录的血流参数，在3D血管模型中进行血流量的CFD模拟。 实际和虚拟2D血管造影记录之间的对应程度由患者的相同角度和调整的记录几何形状确定，并与预先确定的容差值进行比较。 CFD模拟被迭代优化，同时根据比较改变血流参数。 当达到最佳CFD模拟时，输出对应度。

公开(公告)号：US08386019B2

公开(公告)日：2013-02-26

申请号：US12070885

申请日：2008-02-21

申请人： Estelle Camus ,  Oliver Meissner ,  Martin Ostermeier ,  Thomas Redel

发明人： Estelle Camus ,  Oliver Meissner ,  Martin Ostermeier ,  Thomas Redel

IPC分类号： A61B5/05

CPC分类号： A61B34/70 ,  A61B34/30 ,  A61B2017/00699 ,  A61B2017/00703 ,  A61B2090/364 ,  A61B2090/376 ,  A61B2090/3762

摘要： The invention relates to an arrangement for assisting a percutaneous intervention, comprising an imaging system for tomographic imaging, a robot registered therewith and devices for capturing movements of the patient. A processing unit registers a 4D image dataset recorded before the intervention with a 2D or 3D image dataset of the patient which was recorded immediately before the intervention by the imaging system at a defined respiratory position. From this image data, the access path is transmitted to the robot as a function of the movements captured during recording the 4D image dataset and registration, said robot in turn, depending on the instantaneous movement data, holding the instrument on a predetermined target path and preventing the instrument from being advanced by the person if and as long as the instantaneous movement data does not match the previously recorded movement data. The arrangement reduces the risk of puncture errors.

摘要翻译： 本发明涉及一种用于辅助经皮干预的装置，包括用于层析成像的成像系统，与其注册的机器人以及用于捕获患者运动的装置。 处理单元将在介入之前记录的4D图像数据集与由被成像系统干预的紧急记录在定义的呼吸位置之间的患者的2D或3D图像数据集进行注册。 根据该图像数据，根据记录4D图像数据集并记录时记录的运动的函数，根据瞬时移动数据将仪器保持在预定的目标路径上，将访问路径传送到机器人，并且 如果和瞬时移动数据与先前记录的移动数据不匹配，则防止该仪器被人推进。 该布置降低了穿刺错误的风险。

公开(公告)号：US20120323547A1

公开(公告)日：2012-12-20

申请号：US13526719

申请日：2012-06-19

申请人： Sajjad Hussain Baloch ,  Sandra Sudarsky ,  Ying Zhu ,  Ashraf Mohamed ,  Komal Dutta ,  Durga Namburu ,  Puthenveettil Nias ,  Gary S. Martucci ,  Thomas Redel

发明人： Sajjad Hussain Baloch ,  Sandra Sudarsky ,  Ying Zhu ,  Ashraf Mohamed ,  Komal Dutta ,  Durga Namburu ,  Puthenveettil Nias ,  Gary S. Martucci ,  Thomas Redel

IPC分类号： G06G7/48

CPC分类号： G06F19/3437 ,  G06F19/00 ,  G16H50/50

摘要： A method (100) of aneurysm analysis (110) and virtual stent simulation (120) for endovascular treatment of sidewall intracranial aneurysms.

摘要翻译： 用于动脉瘤分析（110）的方法（100）和用于侧壁颅内动脉瘤的血管内治疗的虚拟支架模拟（120）。

公开(公告)号：US08229198B2

公开(公告)日：2012-07-24

申请号：US12319517

申请日：2009-01-08

申请人： Marcus Pfister ,  Thomas Redel

发明人： Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00 ,  A61K49/04

CPC分类号： A61B6/504 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/5229 ,  A61B6/5235 ,  A61B6/5241

摘要： Method for creating image recordings of blood vessel system of a patient, comprising: after administering contrast agent an image recording is created in a first image recording region of a first position of a detector, the diffusion of the contrast agent is observed to determine a current diffusion position; the position of the detector is changed to a second position as a function of the current diffusion position; an image recording of a second image recording region of the second position of the detector is created; and a part of an image recording in the first position extending in the region between the current diffusion position and the end of the first image recording region and recorded without contrast agent is used as a mask to evaluate a locationally correlated part, recorded with contrast agent, of the image recording in the second position for digital subtraction angiography.

摘要翻译： 一种用于创建患者血管系统图像记录的方法，包括：在给予造影剂之后，在检测器的第一位置的第一图像记录区域中产生图像记录，观察造影剂的扩散以确定电流 扩散位置; 检测器的位置作为当前扩散位置的函数被改变到第二位置; 创建检测器的第二位置的第二图像记录区域的图像记录; 并且使用在当前扩散位置和第一图像记录区域的末端之间的区域中延伸并且没有造影剂记录的第一位置的图像记录的一部分作为掩模来评估用造影剂记录的位置相关部分 ，用于数字减影血管造影术的第二位置的图像记录。

公开(公告)号：US20120065498A1

公开(公告)日：2012-03-15

申请号：US12881925

申请日：2010-09-14

申请人： Thomas Redel ,  Michael Maschke ,  Frederik Bender

发明人： Thomas Redel ,  Michael Maschke ,  Frederik Bender

IPC分类号： A61B5/05 ,  A61B8/00

CPC分类号： A61B8/12 ,  A61B8/0883 ,  A61B8/488

摘要： A system and method of treatment of mitral valve insufficiency using an implantable medical device is described. The system uses a C-arm X-ray device configured to produce computed-tomographic (CT)-like images, and to superimpose the CT-like images on a fluoroscopic image taken with the same X-ray device as a part of the treatment procedure. The fluoroscopic images are used to guide a catheter in the patient so as to place the medical device in a proper position. The efficacy of the procedure may be assessed using a non-invasive or minimally invasive acoustic imaging technique.

摘要翻译： 描述了使用可植入医疗装置治疗二尖瓣关闭不全的系统和方法。 该系统使用配置为产生计算机断层摄影（CT）的图像的C臂X射线装置，并且将CT样图像叠加在作为治疗的一部分的相同X射线装置拍摄的荧光镜图像上 程序。 透视图像用于引导患者中的导管，以将医疗装置放置在适当的位置。 可以使用非侵入性或微创声学成像技术来评估该程序的功效。

公开(公告)号：US20110224904A1

公开(公告)日：2011-09-15

申请号：US13043553

申请日：2011-03-09

申请人： Wendelin Feiten ,  Thomas Redel ,  Raoul Daniel Zöllner

发明人： Wendelin Feiten ,  Thomas Redel ,  Raoul Daniel Zöllner

IPC分类号： G06F17/00 ,  A61B6/08

CPC分类号： A61B6/102 ,  A61B6/4441

摘要： A method for monitoring a spatial environment of a mobile device is provided. During the movement of the device along a predefined path, a three-dimensional spatial region of the spatial environment is captured by a detection device. A three-dimensional environment model is created and/or updated from the captured spatial region at cyclical intervals and is specified by spatial volumes in the spatial region occupied by objects. Actions of the device for preventing a collision with the objects and a risk of collision are determined. One of the actions is then performed if the risk of collision exceeds a predefined value. The method has the advantage that actions for collision avoidance are calculated preemptively at cyclical intervals, so that one of the actions can be performed with a short latency period in an impending collision, that is if the risk of collision exceeds the predefined value.

摘要翻译： 提供了一种用于监视移动设备的空间环境的方法。 在装置沿着预定义的路径运动期间，空间环境的三维空间区域由检测装置捕获。 从捕获的空间区域以循环间隔创建和/或更新三维环境模型，并且由对象占据的空间区域中的空间体积来指定。 确定用于防止与物体碰撞的设备的动作和碰撞的风险。 如果碰撞的风险超过预定值，则执行其中一个动作。 该方法具有以下优点：以循环间隔先行计算冲突避免的动作，从而可以在即将发生的冲突中以较短的潜伏期执行其中一个动作，即碰撞风险超过预定值。

公开(公告)号：US07903856B2

公开(公告)日：2011-03-08

申请号：US11901674

申请日：2007-09-18

申请人： Marcus Pfister ,  Thomas Redel

发明人： Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00

CPC分类号： A61B5/055 ,  A61B5/02007 ,  A61B6/032 ,  A61B6/481 ,  A61B6/504 ,  A61B90/36 ,  A61B2017/00778 ,  A61B2090/364 ,  A61B2090/376 ,  G06T5/50 ,  G06T7/136 ,  G06T7/30 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/30101 ,  Y10S378/901

摘要： The invention relates to a method for post-processing a 3D image data set of a vessel structure of a human or animal body, in which a 2D DSA (Digital Subtraction Angiography) of the vessel structure is recorded and registered with the 3D image data set. The 2D DSA is compared with a corresponding projection image computed from the 3D data set and this is changed, e.g. by changing the segmentation parameters, to adapt it to the 2D DSA. This enables the outstanding local resolution of the 2D DSA to be used for improving the 3D image data set.

摘要翻译： 本发明涉及一种用于后处理人或动物体的血管结构的3D图像数据集的方法，其中记录血管结构的2D DSA（数字减影血管造影）并将其与3D图像数据集对齐 。 将2D DSA与从3D数据集计算的相应投影图像进行比较，并且将其改变，例如， 通过改变分割参数，使其适应2D DSA。 这使得2D DSA的出色局部分辨率可用于改进3D图像数据集。