公开(公告)号：US20100329523A1

公开(公告)日：2010-12-30

申请号：US12825785

申请日：2010-06-29

申请人： Martin Ostermeier ,  Marcus Pfister ,  Thomas Redel

发明人： Martin Ostermeier ,  Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00

CPC分类号： A61B6/504 ,  A61B6/463 ,  A61B6/503 ,  A61B6/5235 ,  G06T11/001

摘要： A method for computing a color-coded analysis image of an examination area of an examination object from a temporal sequence of fluoroscopic images of the examination area comprising a vascular system containing arteries and/or veins is provided. An acquisition time instant has been assigned to each of the fluoroscopic images representing a given distribution of a material embolizing some of the vascular system. The fluoroscopic image spatially corresponds to an analysis image pixel by pixel. A computer receives the fluoroscopic images with a color attribute assigned to each pixel of the analysis image at an image point and a time instant. If a pixel differs from a pixel at a preceding time instant, the color attribute assumes a color attribute of the time instant and the difference. If a pixel corresponds to a background color of the analysis image, the color attribute assumes a background color.

摘要翻译： 提供了一种用于从包括含有动脉和/或静脉的血管系统的检查区域的荧光透视图像的时间序列计算检查对象的检查区域的颜色编码分析图像的方法。 已经将采集时刻分配给表示栓塞一些血管系统的材料的给定分布的每个透视图。 透视图像在空间上对应于逐像素的分析图像。 计算机接收在图像点和时刻分配给分析图像的每个像素的颜色属性的透视图像。 如果像素与前一时刻的像素不同，则颜色属性假定时刻的颜色属性和差异。 如果像素对应于分析图像的背景颜色，则颜色属性假定为背景颜色。

公开(公告)号：US08948475B2

公开(公告)日：2015-02-03

申请号：US12825785

申请日：2010-06-29

申请人： Martin Ostermeier ,  Marcus Pfister ,  Thomas Redel

发明人： Martin Ostermeier ,  Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00 ,  A61B6/00 ,  G06T11/00

CPC分类号： A61B6/504 ,  A61B6/463 ,  A61B6/503 ,  A61B6/5235 ,  G06T11/001

摘要： A method for computing a color-coded analysis image of an examination area of an examination object from a temporal sequence of fluoroscopic images of the examination area comprising a vascular system containing arteries and/or veins is provided. An acquisition time instant has been assigned to each of the fluoroscopic images representing a given distribution of a material embolizing some of the vascular system. The fluoroscopic image spatially corresponds to an analysis image pixel by pixel. A computer receives the fluoroscopic images with a color attribute assigned to each pixel of the analysis image at an image point and a time instant. If a pixel differs from a pixel at a preceding time instant, the color attribute assumes a color attribute of the time instant and the difference. If a pixel corresponds to a background color of the analysis image, the color attribute assumes a background color.

摘要翻译： 提供了一种用于从包括含有动脉和/或静脉的血管系统的检查区域的荧光透视图像的时间序列计算检查对象的检查区域的颜色编码分析图像的方法。 已经将采集时刻分配给表示栓塞一些血管系统的材料的给定分布的每个透视图。 透视图像在空间上对应于逐像素的分析图像。 计算机接收在图像点和时刻分配给分析图像的每个像素的颜色属性的透视图像。 如果像素与前一时刻的像素不同，则颜色属性假定时刻的颜色属性和差异。 如果像素对应于分析图像的背景颜色，则颜色属性假定为背景颜色。

公开(公告)号：US20070038125A1

公开(公告)日：2007-02-15

申请号：US11473412

申请日：2006-06-23

申请人： Martin Kleen ,  Marcus Pfister ,  Thomas Redel

发明人： Martin Kleen ,  Marcus Pfister ,  Thomas Redel

IPC分类号： A61B6/00

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61K49/1818 ,  B82Y5/00 ,  G01B9/02091 ,  H01L2924/0002 ,  H01L2924/00

摘要： The present invention relates to an imaging method with an OCT catheter for visualizing molecular functional processes in vulnerable plaques of a blood vessel of the blood vessel system of a patient, with OCT images of the contrast medium-marked vulnerable plaque being generated during continuously controlled movement of the light-emitting and light-absorbing OCT catheter head along the vulnerable plaque after the intravascular injection of a contrast medium into the blood vessel system and after the intravascular insertion of an imaging OCT catheter into the blood vessel comprising the vulnerable plaque.

摘要翻译： 本发明涉及一种具有OCT导管的成像方法，用于在患者的血管系统的血管的易损斑块中可视化分子功能过程，其中在持续控制运动期间产生造影剂标记的易损斑块的OCT图像 的血管内注射造影剂进入血管系统之后和血管内插入成像OCT导管进入包含易损斑块的血管中的易发生斑块的发光和光吸收OCT导管头。

公开(公告)号：US08103067B2

公开(公告)日：2012-01-24

申请号：US11821054

申请日：2007-06-21

申请人： Jan Boese ,  Estelle Camus ,  Marcus Pfister ,  Thomas Redel

发明人： Jan Boese ,  Estelle Camus ,  Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00 ,  G06K9/34

CPC分类号： G06K9/4642 ,  G06K2209/05

摘要： There is described an analysis method for at least one image data record of an examination object, wherein each image data record features a multiplicity of image data elements. A position in a multidimensional space is assigned to each image data element. Each image data element features an image data value. The image data values of positionally corresponding image data elements of the image data records are specified by means of at least essentially positionally identical regions of the examination object. A computer automatically divides the image data records into empty regions and signal regions, applying an overall assignment rule which is based on the image data values of the image data elements of a plurality of image data records, such that each image data element of each image data record is assigned to either its empty region or its signal region. For each image data record, the computer automatically determines a closed outline which fully contains the signal region of the relevant image data record and, on the basis of the closed outline of the relevant image data record, determines an analysis region such that a further analysis of the relevant image data record can be restricted to its analysis region.

摘要翻译： 描述了用于检查对象的至少一个图像数据记录的分析方法，其中每个图像数据记录具有多个图像数据元素。 将多维空间中的位置分配给每个图像数据元素。 每个图像数据元素具有图像数据值。 图像数据记录的位置对应的图像数据元素的图像数据值通过至少基本位置上相同的检查对象的区域来指定。 计算机自动将图像数据记录分为空区域和信号区域，应用基于多个图像数据记录的图像数据元素的图像数据值的总分配规则，使得每个图像的每个图像数据元素 数据记录被分配到其空区域或其信号区域。 对于每个图像数据记录，计算机自动确定完全包含相关图像数据记录的信号区域的封闭轮廓，并且基于相关图像数据记录的闭合轮廓确定分析区域，使得进一步分析 的相关图像数据记录可以限于其分析区域。

公开(公告)号：US20100329526A1

公开(公告)日：2010-12-30

申请号：US12825369

申请日：2010-06-29

申请人： Marcus Pfister ,  Thomas Redel

发明人： Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/62

CPC分类号： A61B6/5235 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5217 ,  G06T7/254 ,  G06T2207/10121 ,  G06T2207/30101

摘要： A determination method for reinitialization of a temporal sequence of fluoroscopic images of an examination region of an examination object is provided. The examination region comprises a vascular system including arteries and/or veins. An acquisition time is assigned to each of the images representing a given distribution of a substance in the examination region at the acquisition time. A computer receives the temporal sequence of the images, determines an evaluation image corresponding spatially on a pixel-by-pixel basis to the images, and calculates a differential value between a pixel of the evaluation image at a time and a pixel at a preceding time during a time characteristic of the sequence. A reinitialization of the temporal sequence of the images is performed at a specific time and thereafter the determination method is started over and/or repeated. The specific time is determined as a function of at least one previously calculated differential value.

摘要翻译： 提供了一种用于重新初始化检查对象的检查区域的荧光透视图像的时间序列的确定方法。 检查区域包括包括动脉和/或静脉的血管系统。 在采集时间将采集时间分配给表示检查区域中物质的给定分布的每个图像。 计算机接收图像的时间序列，确定在图像上逐像素地对应的评估图像，并计算一次评估图像的像素与前一时刻的像素之间的差分值 在序列的时间特征。 在特定时间执行图像的时间序列的重新初始化，此后，确定方法开始和/或重复。 确定具体时间作为至少一个先前计算的微分值的函数。

公开(公告)号：US20080212857A1

公开(公告)日：2008-09-04

申请号：US11901674

申请日：2007-09-18

申请人： Marcus Pfister ,  Thomas Redel

发明人： Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00

CPC分类号： A61B5/055 ,  A61B5/02007 ,  A61B6/032 ,  A61B6/481 ,  A61B6/504 ,  A61B90/36 ,  A61B2017/00778 ,  A61B2090/364 ,  A61B2090/376 ,  G06T5/50 ,  G06T7/136 ,  G06T7/30 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/30101 ,  Y10S378/901

摘要： The invention relates to a method for post-processing a 3D image data set of a vessel structure of a human or animal body, in which a 2D DSA (Digital Subtraction Angiography) of the vessel structure is recorded and registered with the 3D image data set. The 2D DSA is compared with a corresponding projection image computed from the 3D data set and this is changed, e.g. by changing the segmentation parameters, to adapt it to the 2D DSA. This enables the outstanding local resolution of the 2D DSA to be used for improving the 3D image data set.

摘要翻译： 本发明涉及一种用于后处理人或动物体的血管结构的3D图像数据集的方法，其中记录血管结构的2D DSA（数字减影血管造影）并将其与3D图像数据集对齐 。 将2D DSA与从3D数据集计算的相应投影图像进行比较，并且将其改变，例如， 通过改变分割参数，使其适应2D DSA。 这使得2D DSA的出色局部分辨率可用于改进3D图像数据集。

公开(公告)号：US07408648B2

公开(公告)日：2008-08-05

申请号：US11429176

申请日：2006-05-05

申请人： Martin Kleen ,  Marcus Pfister ,  Thomas Redel

发明人： Martin Kleen ,  Marcus Pfister ,  Thomas Redel

IPC分类号： G01B9/02 ,  G01B11/02

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/02007

摘要： The invention relates to a method for tomographically displaying a cavity by optical coherence tomography (OCT) and to an OCT device, wherein the path length of a measuring light beam in the catheter can change as a result of a movement of the catheter and brings about a change in the display scale, wherein a possible change in the path length of the measuring light beam in the event of a movement of the catheter is electronically determined and automatically compensated.

摘要翻译： 本发明涉及一种用于通过光学相干断层摄影（OCT）和OCT装置层析显示腔的方法，其中导管中的测量光束的路径长度可以由于导管的运动而改变，并带来 显示尺度的变化，其中电子地确定导管移动时测量光束的路径长度的可能变化并自动补偿。

公开(公告)号：US20080009698A1

公开(公告)日：2008-01-10

申请号：US11805216

申请日：2007-05-22

申请人： Jan Boese ,  Estelle Camus ,  Marcus Pfister ,  Thomas Redel

发明人： Jan Boese ,  Estelle Camus ,  Marcus Pfister ,  Thomas Redel

IPC分类号： A61B5/05

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/481 ,  A61B6/507 ,  G06T5/50 ,  G06T7/0012 ,  G06T7/33 ,  G06T7/38 ,  G06T2200/04 ,  G06T2207/20016 ,  G06T2207/30048 ,  G06T2207/30101

摘要： The present invention relates to a method and to a device for visualizing objects, in particular non-rigid objects. The method and the device are particularly suitable to visualizing three-dimensional objects in the case of medical interventions.The method comprises: providing a three-dimensional image data record of the object, successively taking a series of two-dimensional image data records of the object, individually registering each individual two-dimensional image data record with the three-dimensional image data record, functionally evaluating functional parameters from the successively taken two-dimensional images, extracting two-dimensional projections from the three-dimensional image data record, and superimposing the recorded two-dimensional images with the extracted two-dimensional projections. A clean copy of the abstract that incorporates the above amendments is provided herewith on a separate page.

摘要翻译： 本发明涉及用于可视化对象，特别是非刚性对象的方法和装置。 该方法和装置特别适用于在医疗干预的情况下可视化三维物体。 该方法包括：提供对象的三维图像数据记录，连续地采取一系列对象的二维图像数据记录，将每个单独的二维图像数据记录与三维图像数据记录对齐， 从连续拍摄的二维图像中功能评估功能参数，从三维图像数据记录中提取二维投影，并将所记录的二维图像与所提取的二维投影重叠。 包含上述修订的摘要的干净的副本将提供在单独的页面上。

公开(公告)号：US08712131B2

公开(公告)日：2014-04-29

申请号：US12825369

申请日：2010-06-29

申请人： Marcus Pfister ,  Thomas Redel

发明人： Marcus Pfister ,  Thomas Redel

IPC分类号： G06K9/00

CPC分类号： A61B6/5235 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5217 ,  G06T7/254 ,  G06T2207/10121 ,  G06T2207/30101

摘要： A determination method for reinitialization of a temporal sequence of fluoroscopic images of an examination region of an examination object is provided. The examination region comprises a vascular system including arteries and/or veins. An acquisition time is assigned to each of the images representing a given distribution of a substance in the examination region at the acquisition time. A computer receives the temporal sequence of the images, determines an evaluation image corresponding spatially on a pixel-by-pixel basis to the images, and calculates a differential value between a pixel of the evaluation image at a time and a pixel at a preceding time during a time characteristic of the sequence. A reinitialization of the temporal sequence of the images is performed at a specific time and thereafter the determination method is started over and/or repeated. The specific time is determined as a function of at least one previously calculated differential value.

摘要翻译： 提供了一种用于重新初始化检查对象的检查区域的荧光透视图像的时间序列的确定方法。 检查区域包括包括动脉和/或静脉的血管系统。 在采集时间将采集时间分配给表示检查区域中物质的给定分布的每个图像。 计算机接收图像的时间序列，确定在图像上逐像素地对应的评估图像，并计算一次评估图像的像素与前一时刻的像素之间的差分值 在序列的时间特征。 在特定时间执行图像的时间序列的重新初始化，此后，确定方法开始和/或重复。 确定具体时间作为至少一个先前计算的微分值的函数。

公开(公告)号：US20120078602A1

公开(公告)日：2012-03-29

申请号：US13246111

申请日：2011-09-27

申请人： Marcus Pfister ,  Thomas Redel

发明人： Marcus Pfister ,  Thomas Redel

IPC分类号： G06G7/60

CPC分类号： A61B6/504 ,  A61B6/4233 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/507 ,  A61B6/5235 ,  A61B2034/105 ,  G16H50/50

摘要： A method for predicting aneurysm growth based on CFD simulations derived from at least two angiography recordings is proposed. A first 3-D recording of the aneurysm is recorded at a first time and a first vascular geometry is determined for simulating a first CFD simulation. A second 3-D recording is recorded at a second time and a second vascular geometry is determined for simulating a second CFD simulation. The two 3-D recordings are registered and a local growth rate is determined from the two 3-D recordings. The local growth rate is correlated between the two vascular geometries with hemodynamically derived parameters from the first CFD simulation. A future vascular geometry and/or a future local growth rate is predicted based on the correlation parameters, the hemodynamic parameters from the second CFD simulation and the second vascular geometry.

摘要翻译： 提出了一种基于来自至少两个血管造影记录的CFD模拟预测动脉瘤生长的方法。 第一次记录动脉瘤的第一个3-D记录，并且确定用于模拟第一个CFD模拟的第一血管几何形状。 在第二时间记录第二个3-D记录，并且确定用于模拟第二个CFD模拟的第二血管几何形状。 两个3-D记录被记录，并且从两个3-D记录确定局部增长率。 本地生长速率与来自第一CFD模拟的血液动力学派生参数的两个血管几何形状相关。 基于相关参数，来自第二CFD模拟的血液动力学参数和第二血管几何，预测未来血管几何形状和/或未来局部生长速率。