公开(公告)号：US20110150183A1

公开(公告)日：2011-06-23

申请号：US12962972

申请日：2010-12-08

申请人： Xiaoye Wu ,  David Allen Langan ,  Jiang Hsieh ,  Robert Franklin Senzig ,  Hao Lia ,  Dan Xu ,  Thomas Matthew Benson

发明人： Xiaoye Wu ,  David Allen Langan ,  Jiang Hsieh ,  Robert Franklin Senzig ,  Hao Lia ,  Dan Xu ,  Thomas Matthew Benson

IPC分类号： H05G1/64

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/405 ,  A61B6/482 ,  A61B6/505 ,  G06T11/005 ,  G06T2211/408

摘要： The present disclosure relates to the generation of dual-energy X-ray data using a data sampling rate comparable to the rate utilized for single-energy imaging. In accordance with the present technique a reduced kVp switching rate is employed compared to conventional dual-energy imaging. Full angular resolution is achieved in the generated images.

摘要翻译： 本公开涉及使用与用于单能量成像的速率相当的数据采样率来生成双能量X射线数据。 根据本技术，与传统的双能量成像相比，采用了降低的kVp开关速率。 在生成的图像中实现全角度分辨率。

公开(公告)号：US07929659B2

公开(公告)日：2011-04-19

申请号：US12179298

申请日：2008-07-24

申请人： Xiaoye Wu ,  Fang Frank Dong ,  James Walter Leblanc

发明人： Xiaoye Wu ,  Fang Frank Dong ,  James Walter Leblanc

IPC分类号： A61B6/03

CPC分类号： A61B6/032 ,  A61B6/4028 ,  A61B6/583 ,  Y10S378/901

摘要： A computed tomographic imaging system is provided for generating computed tomography images. The computed tomographic system includes a processor configured to access image data encoding X-ray projections at a detector position and a plurality of X-ray source beam focal spot positions and to align pixel values for the projections in a direction of deviation of the positions. The processor is also configured to determine a correction factor for at least one of the projections based upon the aligned pixel values and upon a sum of the projections and to correct the pixel values for the at least one of the projections based upon the correction factor.

摘要翻译： 提供计算机断层摄影系统用于生成计算机断层摄影图像。 计算机断层摄影系统包括处理器，其被配置为访问在检测器位置处编码X射线投影的图像数据和多个X射线源束焦点位置，并且在位置的偏离方向上对准投影的像素值。 处理器还被配置为基于对准的像素值和投影的总和来确定至少一个投影的校正因子，并且基于校正因子来校正至少一个投影的像素值。

公开(公告)号：US07756239B2

公开(公告)日：2010-07-13

申请号：US11608162

申请日：2006-12-07

申请人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

发明人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

IPC分类号： A61B6/00

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/481 ,  A61B6/482 ,  A61B6/583

摘要： A diagnostic imaging system in an example comprises a high frequency electromagnetic energy source, a detector, a data acquisition system (DAS), and a computer. The high frequency electromagnetic energy source emits a beam of high frequency electromagnetic energy toward an object to be imaged and be resolved by the system. The detector receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source. The DAS is operably connected to the detector. The computer is operably connected to the DAS and programmed to employ an inversion table or function to convert N+2 measured projections at different incident spectra into material specific integrals for N+2 materials that comprise two non K-edge basis materials and N K-edge contrast agents. N comprises an integer greater than or equal to 1.

摘要翻译： 示例中的诊断成像系统包括高频电磁能源，检测器，数据采集系统（DAS）和计算机。 高频电磁能源向待成像对象发射高频电磁能束，并由系统解决。 检测器接收高频电磁能源发出的高频电磁能。 DAS可操作地连接到检测器。 计算机可操作地连接到DAS并被编程为采用反演台或功能来将不同入射光谱下的N + 2个测量的投影转换为包含两个非K边缘基础材料的N + 2材料的材料特定积分，并且N K- 边缘造影剂。 N包括大于或等于1的整数。

公开(公告)号：US07697657B2

公开(公告)日：2010-04-13

申请号：US11690245

申请日：2007-03-23

申请人： Deborah Joy Walter ,  Xiaoye Wu ,  John Eric Tkaczyk ,  Yanfeng Du

发明人： Deborah Joy Walter ,  Xiaoye Wu ,  John Eric Tkaczyk ,  Yanfeng Du

IPC分类号： A61B6/00

CPC分类号： A61B6/505 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/583

摘要： A system and method of density and effective atomic number imaging include a computer programmed to acquire projection data from the detector of an unknown material at the time of projection data acquisition. The computer is also programmed to generate a density image for the unknown material based on a calibration of two or more known basis materials and to generate an effective atomic number (Z) for the unknown material based on the calibration of two or more known basis materials and based on a function arctan of a ratio of atomic numbers of the two or more known basis materials. The density and effective atomic number images are stored to a computer readable storage medium.

摘要翻译： 密度和有效原子序数成像的系统和方法包括被编程为在投影数据采集时从未知材料的检测器获取投影数据的计算机。 计算机还被编程为基于两种或多种已知基础材料的校准产生未知材料的密度图像，并且基于两种或更多种已知基础材料的校准来产生未知材料的有效原子序数（Z） 并且基于两种或多种已知基础材料的原子序数比的函数关系。 密度和有效原子序数图像被存储到计算机可读存储介质中。

公开(公告)号：US07613274B2

公开(公告)日：2009-11-03

申请号：US11941175

申请日：2007-11-16

申请人： John Eric Tkaczyk ,  Jonathan D. Short ,  Yanfeng Du ,  Wen Li ,  Xiaoye Wu

发明人： John Eric Tkaczyk ,  Jonathan D. Short ,  Yanfeng Du ,  Wen Li ,  Xiaoye Wu

IPC分类号： G01N23/00

CPC分类号： G01T1/20 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/482 ,  G01T1/242 ,  G01T1/249

摘要： A diagnostic imaging system includes an x-ray source that emits a beam of x-ray energy toward an object to be imaged and an energy discriminating (ED) detector that receives the x-ray energy emitted by the x-ray energy source. The ED detector includes a first layer having a first thickness, wherein the first layer comprises a semiconductor configurable to operate in at least an integrating mode and a second layer having a second thickness greater than the first thickness, and configured to receive x-rays that pass through the first layer. The system further includes a data acquisition system (DAS) operably connected to the ED detector and a computer that is operably connected to the DAS. The computer is programmed to identify saturated data in the second layer and substitute the saturated data with non-saturated data from a corresponding pixel in the first layer.

摘要翻译： 诊断成像系统包括向待成像对象发射X射线能量束的x射线源和接收由x射线能量源发射的x射线能量的能量鉴别（ED）检测器。 ED检测器包括具有第一厚度的第一层，其中第一层包括可配置成至少以积分模式操作的半导体和具有大于第一厚度的第二厚度的第二层，并且被配置为接收x射线， 通过第一层。 该系统还包括可操作地连接到ED检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。 计算机被编程为识别第二层中的饱和数据，并用来自第一层中的对应像素的非饱和数据替换饱和数据。

公开(公告)号：US20090214095A1

公开(公告)日：2009-08-27

申请号：US12035072

申请日：2008-02-21

申请人： Xiaoye Wu ,  David Allen Langan ,  James Walter LeBlanc

发明人： Xiaoye Wu ,  David Allen Langan ,  James Walter LeBlanc

IPC分类号： G06K9/00

CPC分类号： G06T5/002 ,  G06T2207/10081 ,  G06T2207/30004

摘要： In dual energy CT, through basis material decomposition (BMD), a pair of density images can be reconstructed. The noises in this image pair are negatively correlated due to the BMD process. A technique is presented for obtaining the monochromatic images at desired energy levels with reduced correlation noise. The technique includes obtaining a plurality of optimum attenuation coefficients for an energy level, selecting a desired energy level, obtaining a plurality of desired attenuation coefficients for the desired energy level, computing a scaling factor for a corresponding noise component based on the optimum attenuation coefficients and the desired attenuation coefficients, and generating a monochromatic image based upon the scaling factor.

摘要翻译： 在双能量CT中，通过基础材料分解（BMD），可以重构一对密度图像。 由于BMD过程，该图像对中的噪声是负相关的。 提出了一种技术，用于以降低的相关噪声在期望的能级获得单色图像。 该技术包括获得能量水平的多个最佳衰减系数，选择期望的能级，获得期望能级的多个期望衰减系数，基于最佳衰减系数计算相应噪声分量的缩放因子，以及 期望的衰减系数，以及基于缩放因子产生单色图像。

公开(公告)号：US20090147910A1

公开(公告)日：2009-06-11

申请号：US11952494

申请日：2007-12-07

申请人： Peter Michael Edic ,  Jonathan David Short ,  John Eric Tkaczyk ,  Xiaoye Wu

发明人： Peter Michael Edic ,  Jonathan David Short ,  John Eric Tkaczyk ,  Xiaoye Wu

IPC分类号： G01N23/087

CPC分类号： G01N23/046 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/4241 ,  A61B6/482 ,  G01N2223/419

摘要： An energy-sensitive computed tomography system is provided. The energy-sensitive computed tomography system includes an X-ray source configured to emit an X-ray beam resulting from electrons impinging upon a target material. The energy-sensitive computed tomography system also includes an object positioned within the X-ray beam. The energy-sensitive computed tomography system further includes a detector configured to receive a transmitted beam of the X-rays through the object. The energy-sensitive computed tomography system also includes a filter having an alternating pattern disposed between the X-ray source and the detector, the filter configured to facilitate measuring projection data that can be used to generate low-energy and high-energy spectral information.

摘要翻译： 提供了一种能量敏感的计算机断层摄影系统。 能量敏感的计算机断层摄影系统包括被配置为发射由撞击在目标材料上的电子产生的X射线束的X射线源。 能量敏感的计算机断层摄影系统还包括位于X射线束内的物体。 能量敏感的计算机断层摄影系统还包括检测器，其被配置为接收通过物体的X射线的透射束。 能量敏感的计算机断层摄影系统还包括具有设置在X射线源和检测器之间的交替图案的滤光器，滤光器被配置为便于测量可用于产生低能量和高能量光谱信息的投影数据。

公开(公告)号：US20090092219A1

公开(公告)日：2009-04-09

申请号：US11869097

申请日：2007-10-09

申请人： Xiaoye Wu ,  James W. LeBlanc ,  Paavana Sainath ,  Thomas John Myers ,  Charles Hugh Shaughnessy ,  Uwe Wiedmann

发明人： Xiaoye Wu ,  James W. LeBlanc ,  Paavana Sainath ,  Thomas John Myers ,  Charles Hugh Shaughnessy ,  Uwe Wiedmann

IPC分类号： H05G1/60

CPC分类号： A61B6/405 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/482

摘要： A CT system includes a rotatable gantry having an opening for receiving a subject to be scanned, a rotatable gantry having an opening for receiving a subject to be scanned, an x-ray source configured to project x-rays having multiple energies toward the subject, and a generator configured to energize the x-ray source to a first voltage and configured to energize the x-ray source to a second voltage, the first voltage distinct from the second voltage. The system further includes a controller configured to cause the generator to energize the x-ray source to the first voltage for a first duration, acquire imaging data for at least one view during at least the first duration, after the first duration, cause the generator to energize the x-ray source to the second voltage for a second duration, and acquire imaging data for two or more views during at least the second duration.

摘要翻译： CT系统包括具有用于接收待扫描的被摄体的开口的可旋转台架，具有用于接收待扫描的被摄体的开口的可旋转机架;被配置为将具有多个能量的x射线投射到被摄体的X射线源， 以及发生器，其被配置为将所述x射线源激励到第一电压并且被配置为将所述x射线源激励到第二电压，所述第一电压不同于所述第二电压。 该系统还包括控制器，该控制器被配置为使得发生器在第一持续时间内，在至少第一持续时间内，在第一持续时间之后，将x射线源激励到第一电压，从而在第一持续时间之后，获得用于至少一个视图的成像数据， 以将X射线源激励到第二电压持续第二持续时间，并且在至少第二持续时间内获取用于两个或更多个视图的成像数据。

公开(公告)号：US20090052612A1

公开(公告)日：2009-02-26

申请号：US11843031

申请日：2007-08-22

申请人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

发明人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

IPC分类号： A61B6/00

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4411 ,  A61B6/469 ,  A61B6/482 ,  A61B6/505 ,  A61B6/5205 ,  A61B6/5235 ,  G01T1/249 ,  G06T5/002 ,  G06T5/50 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/20216 ,  G06T2207/30004 ,  G06T2207/30112 ,  H01L27/14676

摘要： A system and method of a diagnostic imaging system includes a high frequency electromagnetic energy source that emits a beam of high frequency electromagnetic energy toward an object to be imaged, a detector that receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source and attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to obtain CT scan data with two or more incident energy spectra, decompose the obtained CT scan data into projection CT data of two or more basis materials, reconstruct linearly weighted projections of the two or more basis materials, determine an optimized energy for the two or more basis materials within a region-of-interest (ROI), and form a monochromatic image of the projection CT data at the optimized energy using the two or more basis material projections.

摘要翻译： 诊断成像系统的系统和方法包括：高频电磁能源，其向待成像对象发射高频电磁能束;检测器，其接收高频电磁能源发射的高频电磁能量，并衰减 通过该目的，可操作地连接到检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。 计算机被编程以获得具有两个或更多个入射能谱的CT扫描数据，将获得的CT扫描数据分解成两个或更多个基础材料的投影CT数据，重建两个或多个基础材料的线性加权投影，确定优化的能量 对于感兴趣区域（ROI）中的两个或更多个基础材料，并且使用两个或更多个基础材料投影在优化的能量下形成投影CT数据的单色图像。

公开(公告)号：US20080273666A1

公开(公告)日：2008-11-06

申请号：US11690245

申请日：2007-03-23

申请人： Deborah Joy Walter ,  Xiaoye Wu ,  John Eric Tkaczyk ,  Yanfeng Du

发明人： Deborah Joy Walter ,  Xiaoye Wu ,  John Eric Tkaczyk ,  Yanfeng Du

IPC分类号： H05G1/26

CPC分类号： A61B6/505 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/583

摘要： A system and method of density and effective atomic number imaging include a computer programmed to acquire projection data from the detector of an unknown material at the time of projection data acquisition. The computer is also programmed to generate a density image for the unknown material based on a calibration of two or more known basis materials and to generate an effective atomic number (Z) for the unknown material based on the calibration of two or more known basis materials and based on a function arctan of a ratio of atomic numbers of the two or more known basis materials. The density and effective atomic number images are stored to a computer readable storage medium.

摘要翻译： 密度和有效原子序数成像的系统和方法包括被编程为在投影数据采集时从未知材料的检测器获取投影数据的计算机。 计算机还被编程为基于两种或多种已知基础材料的校准产生未知材料的密度图像，并且基于两种或更多种已知基础材料的校准来产生未知材料的有效原子序数（Z） 并且基于两种或多种已知基础材料的原子序数比的函数关系。 密度和有效原子序数图像被存储到计算机可读存储介质中。