公开(公告)号：US20240156420A1

公开(公告)日：2024-05-16

申请号：US18280001

申请日：2022-03-01

申请人： THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK

发明人： Anthony R. LUBINSKY ,  Wei ZHAO ,  Xiaoyu DUAN ,  Hailiang HUANG ,  Adrian HOWANSKY ,  Jann STAVRO ,  Amirhossein GOLDAN

IPC分类号： A61B6/02 ,  A61B6/00 ,  A61B6/40 ,  A61B6/42 ,  A61B6/50

CPC分类号： A61B6/025 ,  A61B6/4042 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/482 ,  A61B6/502

摘要： Structures and methods operable to detect radiation are described. The structure includes a dual-layer detector imaging device that permits one-shot of x-rays for dual-energy imaging. In one embodiment, a front layer of the detector includes a photon counting detector and aback layer of the detector includes an an x-ray radiation source for absorbing x-ray radiation to separate radiation into low energy and high energy components for incidence upon an imaging object. In an embodiment, the imaging object includes a contrast agent material having a characteristic K-edge atomic energy band level, and the separation filter absorbing the X-ray radiation is near the K-edge atomic energy band level.

公开(公告)号：US11717240B2

公开(公告)日：2023-08-08

申请号：US17288839

申请日：2019-10-25

申请人： THE JOHNS HOPKINS UNIVERSITY

发明人： Joseph Webster Stayman ,  Steven Tilley

IPC分类号： A61B6/00 ,  A61B6/03

CPC分类号： A61B6/4042 ,  A61B6/032

摘要： The present invention is directed to spatial-spectral filtering for multi-material CT decomposition. The invention includes a specialized filter that spectrally shapes an x-ray beam into a number of beamlets with different spectra. The filter allows decomposition of an object/anatomy into different material categories (including different biological types: muscle, fat, etc. or exogenous contrast agents that have been introduced: e.g iodine, gadolinium, etc.). The x-ray beam is spectrally modulated across the face of the detector using a repeating pattern of filter materials. Such spatial-spectral filters allow for collection of many different spectral channels using “source-side” control. However, in contrast to other spectral techniques that provide mathematically complete projection data, spatial-spectral filtered data is sparse in each spectral channel—making traditional projection-domain or image-domain material decomposition difficult to apply. Therefore, the present invention uses model-based material decomposition, which combines reconstruction and multi-material decomposition, and permits arbitrary spectral, spatial, and angular sampling patterns.

公开(公告)号：US20180153486A1

公开(公告)日：2018-06-07

申请号：US15511362

申请日：2016-08-26

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Gerhard MARTENS ,  Udo VAN STEVENDAAL

IPC分类号： A61B6/00 ,  G02B5/18

CPC分类号： A61B6/4042 ,  A61B6/4035 ,  A61B6/4241 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/484 ,  G02B5/1838 ,  G21K1/10 ,  G21K2207/005

摘要： A grating based interferometric X-ray imaging apparatus having an interferometer (IF). The interferometer comprises at least one grating (G1). The grating (G1) is tiltable relative to an optical axis of the X-ray imaging apparatus. This allows changing a design energy of the X-ray imaging apparatus.

公开(公告)号：US20170146466A1

公开(公告)日：2017-05-25

申请号：US15370280

申请日：2016-12-06

申请人： The Johns Hopkins University

发明人： Daniel Stutman ,  Michael Finkenthal

IPC分类号： G01N23/04 ,  G01N23/20 ,  G21K1/06 ,  G01N23/087

CPC分类号： G01N23/04 ,  A61B6/40 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/4241 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/483 ,  A61B6/484 ,  A61B6/505 ,  A61B6/5235 ,  A61B6/583 ,  G01N23/087 ,  G01N23/20075 ,  G01N2223/206 ,  G21K1/067 ,  G21K2207/005 ,  H05G2/001

摘要： A differential phase contrast X-ray imaging system includes an X-ray illumination system, a beam splitter arranged in an optical path of the X-ray illumination system, and a detection system arranged in an optical path to detect X-rays after passing through the beam splitter.

公开(公告)号：US20170000431A1

公开(公告)日：2017-01-05

申请号：US15196658

申请日：2016-06-29

申请人： Martin Spahn

发明人： Martin Spahn

IPC分类号： A61B6/00

CPC分类号： A61B6/4241 ,  A61B6/4042 ,  A61B6/4233 ,  A61B6/461 ,  A61B6/487 ,  A61B6/5205 ,  G01T1/2928

摘要： A method and system for receiving energy selective image data relating to an examination object using a counting, digital X-ray detector, together with a counting, digital X-ray detector and an X-ray system are provided. The X-ray detector includes an X-ray converter for direct or indirect conversion of X-rays into an electrical signal, and a matrix including a plurality of counting pixel elements. For each pixel element of the plurality of counting pixel elements, at least one modifiable threshold value, above which an incoming signal is counted using a memory unit, is applicable.

摘要翻译： 提供了一种使用计数数字X射线检测器与计数，数字X射线检测器和X射线系统一起接收与检查对象有关的能量选择图像数据的方法和系统。 X射线检测器包括用于将X射线直接或间接转换成电信号的X射线转换器，以及包括多个计数像素元件的矩阵。 对于多个计数像素元件中的每个像素元件，可应用至少一个可修改的阈值，使用存储器单元计数输入信号。

公开(公告)号：US09316601B2

公开(公告)日：2016-04-19

申请号：US13981610

申请日：2012-01-25

申请人： Roland Proksa ,  Gerhard Martens

发明人： Roland Proksa ,  Gerhard Martens

IPC分类号： G01N23/04 ,  A61B6/03 ,  A61B6/06 ,  A61B6/00 ,  G06T11/00

CPC分类号： G01N23/04 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4042 ,  A61B6/4241 ,  A61B6/5205 ,  A61B6/5258 ,  G01N23/046 ,  G01N2223/419 ,  G06T11/003

摘要： The invention relates to a detection values processing apparatus. Energy-dependent detection values are provided, which are indicative of polychromatic radiation (4) after having traversed an examination zone (5). The radiation is filtered by a filter (15) which comprises K-edge filter material. A component decomposition technique is applied to the detection values for determining K-edge attenuation values being first component attenuation values, which are indicative of an attenuation caused by the K-edge filter material, and additional component attenuation values, which are indicative of an attenuation caused by additional components of the examination zone, wherein an image of the examination zone is reconstructed from the additional component attenuation values. An image can therefore be reconstructed, which is not adversely affected by the filter, because the K-edge attenuation values are not used for reconstructing the image. This can improve the quality of the reconstructed image.

摘要翻译： 本发明涉及一种检测值处理装置。 提供依赖于能量的检测值，这些检测值指示经过检查区域（5）之后的多色辐射（4）。 辐射由包括K边缘过滤材料的过滤器（15）过滤。 分量分解技术被应用于用于确定作为表示由K边缘滤波器材料引起的衰减的第一分量衰减值的K边缘衰减值的检测值以及指示衰减的附加分量衰减值 由检查区域的附加组件引起，其中从附加分量衰减值重建检查区域的图像。 因此，由于K边缘衰减值不用于重建图像，因此可以重构图像，其不受滤波器的不利影响。 这可以提高重建图像的质量。

公开(公告)号：US09048061B2

公开(公告)日：2015-06-02

申请号：US14094603

申请日：2013-12-02

申请人： Rapiscan Systems, Inc.

发明人： Edward James Morton

IPC分类号： H01J35/02 ,  H01J35/08 ,  G01N23/06 ,  G01V5/00 ,  G01N23/04

CPC分类号： G01N23/087 ,  A61B6/4042 ,  A61B6/482 ,  G01N23/04 ,  G01N23/046 ,  G01N23/06 ,  G01N2223/206 ,  G01V5/00 ,  H01J35/08 ,  H01J2235/086 ,  H01J2235/088

摘要： The present invention is directed toward an X-ray scanner that has an electron source and an anode. The anode has a target surface with a series of material areas spaced along it in a scanning direction. The material areas are formed from different materials. The electron source is arranged to direct electrons at a series of target areas of the target surface, in a predetermined order, so as to generate X-ray beams having different energy spectra.

摘要翻译： 本发明涉及具有电子源和阳极的X射线扫描器。 阳极具有目标表面，其中沿着扫描方向间隔开一系列材料区域。 材料区域由不同的材料形成。 电子源被布置成以预定顺序引导目标表面的一系列目标区域处的电子，以便产生具有不同能量谱的X射线束。

公开(公告)号：US20150110346A1

公开(公告)日：2015-04-23

申请号：US14402121

申请日：2013-05-31

申请人： KONINKLIJKE PHILIPS N.V.

发明人： Carsten Oliver Schirra ,  Ewald Roessl ,  Roland Proksa

IPC分类号： A61B19/00 ,  G06T11/00 ,  G06T7/00

CPC分类号： A61B34/10 ,  A61B6/032 ,  A61B6/4042 ,  A61B6/405 ,  A61B6/4241 ,  A61B6/481 ,  A61B6/488 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5217 ,  A61B6/5235 ,  A61B2034/107 ,  F04C2270/041 ,  G06T7/0012 ,  G06T11/005 ,  G06T2207/10081 ,  G06T2207/30101 ,  G06T2211/404

摘要： A method includes obtaining first spectral image data, which includes at least a first component corresponding to a targeted first K-edge based contrast agent administered to a subject if a target of the targeted first K-edge based contrast agent is present in the subject, decomposing the first spectral image data into at least the first component, reconstructing the first component thereby generating a first image of the targeted first K-edge contrast agent, determining if the targeted first K-edge contrast agent is present in the first image, and generating a signal indicating the targeted first K-edge contrast agent is present in the first image in response to determining the targeted first K-edge contrast agent is present in the first image.

摘要翻译： 一种方法包括获取第一光谱图像数据，该第一光谱图像数据包括至少一个第一组分，所述第一组分对应于被施用于对象的目标第一K边缘造影剂，如果所述目标第一K边缘基础造影剂的目标存在于所述对象中， 将第一光谱图像数据分解成至少第一分量，重构第一分量，从而生成目标第一K边缘造影剂的第一图像，确定目标第一K边缘造影剂是否存在于第一图像中，以及 响应于确定目标的第一K边缘造影剂存在于第一图像中，产生指示目标的第一K边缘造影剂的信号存在于第一图像中。

公开(公告)号：US20140086382A1

公开(公告)日：2014-03-27

申请号：US14028815

申请日：2013-09-17

申请人： Thomas FLOHR ,  Gregor JOST ,  Rrüdiger LAWACZECK ,  Hubertus PIETSCH ,  Bernhard SCHMIDT

发明人： Thomas FLOHR ,  Gregor JOST ,  Rrüdiger LAWACZECK ,  Hubertus PIETSCH ,  Bernhard SCHMIDT

IPC分类号： A61B6/03 ,  A61B6/00

CPC分类号： A61B6/502 ,  A61B6/032 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/481 ,  A61B6/482

摘要： A mammography CT system is disclosed which includes an X-ray generator; and a first radiator-detector system. A contrast medium, including an opacifying element including an absorption peak in a first energy range, is useable for tomographic imaging of a female breast of a patient. After filtering, the X-rays with a prespecified tube voltage that form at an anode, are configured to emit an X-ray spectrum having a second energy range, wherein the radiator-detector system is configured to acquire a plurality of circumferential projections around the breast. The first energy range is a part of the second energy range and the second energy range includes an upper limit of less than 70 keV and a lower limit of greater than 20 keV. A corresponding method for generating tomographic mammography CT images is also disclosed.

摘要翻译： 公开了一种包括X射线发生器的乳房摄影CT系统; 和第一散热器检测器系统。 包括在第一能量范围内包括吸收峰的遮光元件的造影剂可用于患者的女性乳房的层析成像。 在过滤之后，在阳极处形成具有预先规定的管电压的X射线被配置为发射具有第二能量范围的X射线光谱，其中散热器 - 检测器系统被配置为获取周围的多个周向突起 乳房。 第一能量范围是第二能量范围的一部分，第二能量范围包括小于70keV的上限和大于20keV的下限。 还公开了用于产生断层摄影乳房X线照相CT图像的相应方法。

公开(公告)号：US20140005533A1

公开(公告)日：2014-01-02

申请号：US13979154

申请日：2012-01-17

申请人： Michael Grasruck ,  Gregor Jost

发明人： Michael Grasruck ,  Gregor Jost

IPC分类号： A61B6/00 ,  A61B6/03

CPC分类号： A61B6/4042 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4035 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/501 ,  A61B6/504 ,  A61B6/544 ,  A61B6/583 ,  A61K49/04 ,  A61K49/0438 ,  G21K1/10

摘要： A method is disclosed for generating at least one x-ray image of a patient having incorporated contrast medium, using x-rays having an energy spectrum and an x-ray detector. The energy spectrum is modified by at least one first filter arranged in the beam path in front of the patient, the patient absorbing a dose in order to generate detector data for the x-ray image and the x-ray image having a CNR value which represents the ratio of the maximum contrast in the image to the noise. The energy spectrum and contrast medium are matched to each other, taking into account the thickness of the patient to be x-rayed, in such a way that an optimization criterion which is taken from an x-ray image that is generated or simulated by way of trials is maximized. Furthermore, an x-ray system is also disclosed.

摘要翻译： 公开了一种用于使用具有能谱和x射线检测器的X射线产生具有并入造影剂的患者的至少一个X射线图像的方法。 能量谱被布置在患者前面的束路径中的至少一个第一滤波器修改，患者吸收剂量以产生用于X射线图像的检测器数据和具有CNR值的X射线图像，其中CNR值为 表示图像中的最大对比度与噪声的比率。 能量谱和造影剂相互匹配，考虑到要被X射线照射的患者的厚度，使得从通过方式产生或模拟的x射线图像取得的优化标准 的试验得到最大化。 此外，还公开了一种x射线系统。