公开(公告)号：US07724865B2

公开(公告)日：2010-05-25

申请号：US11843031

申请日：2007-08-22

申请人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

发明人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

IPC分类号： A61B6/00

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4411 ,  A61B6/469 ,  A61B6/482 ,  A61B6/505 ,  A61B6/5205 ,  A61B6/5235 ,  G01T1/249 ,  G06T5/002 ,  G06T5/50 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/20216 ,  G06T2207/30004 ,  G06T2207/30112 ,  H01L27/14676

摘要： A system and method of a diagnostic imaging system includes a high frequency electromagnetic energy source that emits a beam of high frequency electromagnetic energy toward an object to be imaged, a detector that receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source and attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to obtain CT scan data with two or more incident energy spectra, decompose the obtained CT scan data into projection CT data of two or more basis materials, reconstruct linearly weighted projections of the two or more basis materials, determine an optimized energy for the two or more basis materials within a region-of-interest (ROI), and form a monochromatic image of the projection CT data at the optimized energy using the two or more basis material projections.

摘要翻译： 诊断成像系统的系统和方法包括：高频电磁能源，其向待成像对象发射高频电磁能束;检测器，其接收高频电磁能源发射的高频电磁能量，并衰减 通过该目的，可操作地连接到检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。 计算机被编程以获得具有两个或更多个入射能谱的CT扫描数据，将获得的CT扫描数据分解成两个或更多个基础材料的投影CT数据，重建两个或多个基础材料的线性加权投影，确定优化的能量 对于感兴趣区域（ROI）中的两个或更多个基础材料，并且使用两个或更多个基础材料投影在优化的能量下形成投影CT数据的单色图像。

公开(公告)号：US20080137803A1

公开(公告)日：2008-06-12

申请号：US11608162

申请日：2006-12-07

申请人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

发明人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

IPC分类号： A61B6/00 ,  G12B13/00

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/481 ,  A61B6/482 ,  A61B6/583

摘要： A diagnostic imaging system in an example comprises a high frequency electromagnetic energy source, a detector, a data acquisition system (DAS), and a computer. The high frequency electromagnetic energy source emits a beam of high frequency electromagnetic energy toward an object to be imaged and be resolved by the system. The detector receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source. The DAS is operably connected to the detector. The computer is operably connected to the DAS and programmed to employ an inversion table or function to convert N+2 measured projections at different incident spectra into material specific integrals for N+2 materials that comprise two non K-edge basis materials and N K-edge contrast agents. N comprises an integer greater than or equal to 1.

摘要翻译： 示例中的诊断成像系统包括高频电磁能源，检测器，数据采集系统（DAS）和计算机。 高频电磁能源向待成像对象发射高频电磁能束，并由系统解决。 检测器接收高频电磁能源发出的高频电磁能。 DAS可操作地连接到检测器。 计算机可操作地连接到DAS并被编程为采用反演台或功能来将不同入射光谱下的N + 2个测量的投影转换为包含两个非K边缘基础材料的N + 2材料的材料特定积分，并且N K- 边缘造影剂。 N包括大于或等于1的整数。

公开(公告)号：US07756239B2

公开(公告)日：2010-07-13

申请号：US11608162

申请日：2006-12-07

申请人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

发明人： Xiaoye Wu ,  Robert F. Senzig ,  Deborah Joy Walter ,  James W. LeBlanc ,  John Eric Tkaczyk

IPC分类号： A61B6/00

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/481 ,  A61B6/482 ,  A61B6/583

摘要： A diagnostic imaging system in an example comprises a high frequency electromagnetic energy source, a detector, a data acquisition system (DAS), and a computer. The high frequency electromagnetic energy source emits a beam of high frequency electromagnetic energy toward an object to be imaged and be resolved by the system. The detector receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source. The DAS is operably connected to the detector. The computer is operably connected to the DAS and programmed to employ an inversion table or function to convert N+2 measured projections at different incident spectra into material specific integrals for N+2 materials that comprise two non K-edge basis materials and N K-edge contrast agents. N comprises an integer greater than or equal to 1.

摘要翻译： 示例中的诊断成像系统包括高频电磁能源，检测器，数据采集系统（DAS）和计算机。 高频电磁能源向待成像对象发射高频电磁能束，并由系统解决。 检测器接收高频电磁能源发出的高频电磁能。 DAS可操作地连接到检测器。 计算机可操作地连接到DAS并被编程为采用反演台或功能来将不同入射光谱下的N + 2个测量的投影转换为包含两个非K边缘基础材料的N + 2材料的材料特定积分，并且N K- 边缘造影剂。 N包括大于或等于1的整数。

公开(公告)号：US20090052612A1

公开(公告)日：2009-02-26

申请号：US11843031

申请日：2007-08-22

申请人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

发明人： Xiaoye Wu ,  John Eric Tkaczyk ,  James W. LeBlanc

IPC分类号： A61B6/00

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4411 ,  A61B6/469 ,  A61B6/482 ,  A61B6/505 ,  A61B6/5205 ,  A61B6/5235 ,  G01T1/249 ,  G06T5/002 ,  G06T5/50 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/20216 ,  G06T2207/30004 ,  G06T2207/30112 ,  H01L27/14676

摘要： A system and method of a diagnostic imaging system includes a high frequency electromagnetic energy source that emits a beam of high frequency electromagnetic energy toward an object to be imaged, a detector that receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source and attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to obtain CT scan data with two or more incident energy spectra, decompose the obtained CT scan data into projection CT data of two or more basis materials, reconstruct linearly weighted projections of the two or more basis materials, determine an optimized energy for the two or more basis materials within a region-of-interest (ROI), and form a monochromatic image of the projection CT data at the optimized energy using the two or more basis material projections.

摘要翻译： 诊断成像系统的系统和方法包括：高频电磁能源，其向待成像对象发射高频电磁能束;检测器，其接收高频电磁能源发射的高频电磁能量，并衰减 通过该目的，可操作地连接到检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。 计算机被编程以获得具有两个或更多个入射能谱的CT扫描数据，将获得的CT扫描数据分解成两个或更多个基础材料的投影CT数据，重建两个或多个基础材料的线性加权投影，确定优化的能量 对于感兴趣区域（ROI）中的两个或更多个基础材料，并且使用两个或更多个基础材料投影在优化的能量下形成投影CT数据的单色图像。

公开(公告)号：US08160200B2

公开(公告)日：2012-04-17

申请号：US12750050

申请日：2010-03-30

申请人： John Eric Tkaczyk ,  David Allen Langan ,  Samit Kumar Basu ,  Xiaoye Wu ,  Bruno Kristiaan Bernard De Man ,  Jeffrey Seymour Gordon

发明人： John Eric Tkaczyk ,  David Allen Langan ,  Samit Kumar Basu ,  Xiaoye Wu ,  Bruno Kristiaan Bernard De Man ,  Jeffrey Seymour Gordon

IPC分类号： H05G1/26

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/405 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/488 ,  A61B6/542

摘要： A technique for acquiring desired image data in an imaging system comprising at least one radiation source and a detector is described. Initially, preliminary image data corresponding to an object may be acquired. Further, at least one parameter associated with the radiation source and corresponding to a particular view angle of the radiation source may be determined based on the preliminary image data and a priori information. Similarly, at least one parameter associated with the detector and corresponding to the particular view angle may be determined based on a priori information and the preliminary image data. Efficient operating modes of the radiation source and the detector corresponding to the particular view angle may be selected based on the determined parameters to achieve a desired system performance. Subsequently, the final image data may be acquired using the selected operating modes of the radiation source and the detector.

摘要翻译： 描述了在包括至少一个辐射源和检测器的成像系统中获取所需图像数据的技术。 首先，可以获取与对象相对应的初步图像数据。 此外，可以基于初步图像数据和先验信息来确定与辐射源相关联并且对应于辐射源的特定视角的至少一个参数。 类似地，可以基于先验信息和初步图像数据来确定与检测器相关联并且对应于特定视角的至少一个参数。 可以基于确定的参数来选择对应于特定视角的辐射源和检测器的有效操作模式以实现期望的系统性能。 随后，可以使用所选择的辐射源和检测器的操作模式来获取最终图像数据。

公开(公告)号：US07606347B2

公开(公告)日：2009-10-20

申请号：US11744292

申请日：2007-05-04

申请人： John Eric Tkaczyk ,  Jonathan D. Short ,  James Wilson Rose ,  Xiaoye Wu ,  Samit Kumar Basu

发明人： John Eric Tkaczyk ,  Jonathan D. Short ,  James Wilson Rose ,  Xiaoye Wu ,  Samit Kumar Basu

IPC分类号： A61B6/03

CPC分类号： A61B6/5205 ,  A61B6/032 ,  A61B6/4291 ,  G01T1/2018 ,  G01T1/242 ,  G01T1/243 ,  G01T1/249

摘要： A CT detector includes a first detector configured to convert radiographic energy to electrical signals representative of energy sensitive radiographic data and a second detector configured to convert radiographic energy to electrical signals representative of energy sensitive radiographic data and positioned to receive x-rays that pass through the first detector. A logic controller is electrically connected to the first detector and the second detector and is configured to receive a logic output signal from the second detector indicative of an amount of a saturation level of the first detector, compare the logic output signal to a threshold value, and output, based on the comparison, electrical signals from the first detector, the second detector, or a combination thereof to an image chain.

摘要翻译： CT检测器包括：第一检测器，其被配置为将射线照相能量转换成表示能量敏感射线照相数据的电信号;以及第二检测器，被配置为将放射线照相能量转换成表示能量敏感射线照相数据的电信号，并被定位成接收穿过 第一检测器 逻辑控制器电连接到第一检测器和第二检测器，并且被配置为从第二检测器接收指示第一检测器的饱和电平的量的逻辑输出信号，将逻辑输出信号与阈值进行比较， 并且基于比较将来自第一检测器，第二检测器或其组合的电信号输出到图像链。

公开(公告)号：US20110243413A1

公开(公告)日：2011-10-06

申请号：US12750050

申请日：2010-03-30

申请人： John Eric Tkaczyk ,  David Allen Langan ,  Samit Kumar Basu ,  Xiaoye Wu ,  Bruno Kristiaan Bernard De Man ,  Jeffrey Seymour Gordon

发明人： John Eric Tkaczyk ,  David Allen Langan ,  Samit Kumar Basu ,  Xiaoye Wu ,  Bruno Kristiaan Bernard De Man ,  Jeffrey Seymour Gordon

IPC分类号： G06K9/00 ,  G01N23/04 ,  H05G1/60

CPC分类号： A61B6/4035 ,  A61B6/032 ,  A61B6/405 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/488 ,  A61B6/542

摘要： A technique for acquiring desired image data in an imaging system comprising at least one radiation source and a detector is described. Initially, preliminary image data corresponding to an object may be acquired. Further, at least one parameter associated with the radiation source and corresponding to a particular view angle of the radiation source may be determined based on the preliminary image data and a priori information. Similarly, at least one parameter associated with the detector and corresponding to the particular view angle may be determined based on a priori information and the preliminary image data. Efficient operating modes of the radiation source and the detector corresponding to the particular view angle may be selected based on the determined parameters to achieve a desired system performance. Subsequently, the final image data may be acquired using the selected operating modes of the radiation source and the detector.

摘要翻译： 描述了在包括至少一个辐射源和检测器的成像系统中获取所需图像数据的技术。 首先，可以获取与对象相对应的初步图像数据。 此外，可以基于初步图像数据和先验信息来确定与辐射源相关联并且对应于辐射源的特定视角的至少一个参数。 类似地，可以基于先验信息和初步图像数据来确定与检测器相关联并且对应于特定视角的至少一个参数。 可以基于确定的参数来选择对应于特定视角的辐射源和检测器的有效操作模式以实现期望的系统性能。 随后，可以使用所选择的辐射源和检测器的操作模式来获取最终图像数据。

公开(公告)号：US07826587B1

公开(公告)日：2010-11-02

申请号：US12558248

申请日：2009-09-11

申请人： David Allen Langan ,  John Eric Tkaczyk ,  James Walter LeBlanc ,  Colin R. Wilson ,  Xiaoye Wu ,  Dan Xu ,  Thomas Matthew Benson ,  Jed Douglas Pack

发明人： David Allen Langan ,  John Eric Tkaczyk ,  James Walter LeBlanc ,  Colin R. Wilson ,  Xiaoye Wu ,  Dan Xu ,  Thomas Matthew Benson ,  Jed Douglas Pack

IPC分类号： H05G1/60

CPC分类号： A61B6/405 ,  A61B6/032 ,  A61B6/482

摘要： A CT system includes a gantry, an x-ray source, a generator configured to energize the x-ray source to a first kVp and to a second kVp, a detector, and a controller. The controller is configured energize the x-ray source to the first kVp for a first time period, subsequently energize the x-ray source to the second kVp for a second time period, integrate data for a first integration period that includes a portion of a steady-state period of the x-ray source at the first kVp, integrate data for a second integration period that includes a portion of a steady-state period of the x-ray source at the second kVp, compare a signal-to-noise ratio (SNR) during the first integration period (SNRH) and the second integration period (SNRL), adjust an operating parameter of the CT system to optimize an SNRH with SNRL, and generate an image using the integrated data.

摘要翻译： CT系统包括台架，x射线源，被配置为将x射线源激发到第一kVp的发生器和到第二kVp的检测器和控制器的发生器。 控制器被配置为在第一时间段内将x射线源激励到第一kVp，随后将x射线源激励到第二kVp第二时间段，将包含第一时间段的第一积分周期的数据整合 在第一kVp处的x射线源的稳态周期，将包括X射线源的稳态周期的一部分的第二积分周期的数据集成在第二kVp处，比较信号与噪声 在第一积分周期（SNRH）和第二积分周期（SNRL）期间的比率（SNR），调整CT系统的运行参数以利用SNRL优化SNRH，并使用积分数据生成图像。

公开(公告)号：US20090129538A1

公开(公告)日：2009-05-21

申请号：US11941175

申请日：2007-11-16

申请人： John Eric Tkaczyk ,  Jonathan D. Short ,  Yanfeng Du ,  Wen Li ,  Xiaoye Wu

发明人： John Eric Tkaczyk ,  Jonathan D. Short ,  Yanfeng Du ,  Wen Li ,  Xiaoye Wu

IPC分类号： A61B6/00 ,  G01T1/20

CPC分类号： G01T1/20 ,  A61B6/032 ,  A61B6/4241 ,  A61B6/482 ,  G01T1/242 ,  G01T1/249

摘要： A diagnostic imaging system includes an x-ray source that emits a beam of x-ray energy toward an object to be imaged and an energy discriminating (ED) detector that receives the x-ray energy emitted by the x-ray energy source. The ED detector includes a first layer having a first thickness, wherein the first layer comprises a semiconductor configurable to operate in at least an integrating mode and a second layer having a second thickness greater than the first thickness, and configured to receive x-rays that pass through the first layer. The system further includes a data acquisition system (DAS) operably connected to the ED detector and a computer that is operably connected to the DAS. The computer is programmed to identify saturated data in the second layer and substitute the saturated data with non-saturated data from a corresponding pixel in the first layer.

摘要翻译： 诊断成像系统包括向待成像对象发射X射线能量束的x射线源和接收由x射线能量源发射的x射线能量的能量鉴别（ED）检测器。 ED检测器包括具有第一厚度的第一层，其中第一层包括可配置成至少以积分模式操作的半导体和具有大于第一厚度的第二厚度的第二层，并且被配置为接收x射线， 通过第一层。 该系统还包括可操作地连接到ED检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。 计算机被编程为识别第二层中的饱和数据，并用来自第一层中的对应像素的非饱和数据替换饱和数据。

公开(公告)号：US07885372B2

公开(公告)日：2011-02-08

申请号：US11952494

申请日：2007-12-07

申请人： Peter Michael Edic ,  Jonathan David Short ,  John Eric Tkaczyk ,  Xiaoye Wu

发明人： Peter Michael Edic ,  Jonathan David Short ,  John Eric Tkaczyk ,  Xiaoye Wu

IPC分类号： A61B6/03 ,  H05G1/60 ,  H05G1/64 ,  G21K3/00

CPC分类号： G01N23/046 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/4241 ,  A61B6/482 ,  G01N2223/419

摘要： An energy-sensitive computed tomography system is provided. The energy-sensitive computed tomography system includes an X-ray source configured to emit an X-ray beam resulting from electrons impinging upon a target material. The energy-sensitive computed tomography system also includes an object positioned within the X-ray beam. The energy-sensitive computed tomography system further includes a detector configured to receive a transmitted beam of the X-rays through the object. The energy-sensitive computed tomography system also includes a filter having an alternating pattern disposed between the X-ray source and the detector, the filter configured to facilitate measuring projection data that can be used to generate low-energy and high-energy spectral information.

摘要翻译： 提供了一种能量敏感的计算机断层摄影系统。 能量敏感的计算机断层摄影系统包括被配置为发射由撞击在目标材料上的电子产生的X射线束的X射线源。 能量敏感的计算机断层摄影系统还包括位于X射线束内的物体。 能量敏感的计算机断层摄影系统还包括检测器，其被配置为接收通过物体的X射线的透射束。 能量敏感的计算机断层摄影系统还包括具有设置在X射线源和检测器之间的交替图案的滤光器，滤光器被配置为便于测量可用于产生低能量和高能量光谱信息的投影数据。