公开(公告)号：US20080285719A1

公开(公告)日：2008-11-20

申请号：US11804693

申请日：2007-05-18

Applicant: Janne Ilmari Nord ,  Sami Pekka Siljamaki ,  Katja Marika Pesola

Inventor： Janne Ilmari Nord ,  Sami Pekka Siljamaki ,  Katja Marika Pesola

IPC: G21K1/04

CPC classification number: G21K1/04 ,  A61N5/103 ,  A61N5/1036 ,  A61N5/1042 ,  G21K1/046

Abstract: Systems and methods of controlling the leaves of an aperture in radiation treatment are disclosed. In some embodiments, these systems and methods allow the delivery of different radiation fluences to different parts of a treatment volume in a single rotation of the aperture around the treatment volume. In some embodiments, different radiation fluences are achieved by radiating different parts of the treatment volume from opposing positions of the aperture around the treatment volume. In some embodiments, different radiation fluences are achieved by assigning different leaf pairs to radiate different parts of the treatment volume.

Abstract translation: 公开了控制辐射处理中孔径叶片的系统和方法。 在一些实施例中，这些系统和方法允许在围绕治疗体积的孔的单次旋转中将不同的辐射通量递送到治疗体积的不同部分。 在一些实施例中，通过将治疗体积的不同部分从围绕治疗体积的孔的相对位置辐射来实现不同的辐射能量密度。 在一些实施例中，通过分配不同的叶对以辐射处理体积的不同部分来实现不同的辐射通量。

公开(公告)号：US20080240348A1

公开(公告)日：2008-10-02

申请号：US11995303

申请日：2006-07-11

Applicant: Srijit Kamath ,  Sartaj Kumar Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

Inventor： Srijit Kamath ,  Sartaj Kumar Sahni ,  Jonathan Li ,  Jatinder Palta ,  Sanjay Ranka

IPC: A61N5/10

CPC classification number: A61N5/1042 ,  A61N5/1036 ,  G21K1/04

Abstract: A method and associated system 300 for delivering intensity-modulated radiation therapy (IMRT) uses variable feathering field splitting for intensity modulated fields of large size. Processor 112 controls a beam-shaping device 106 so that the beam-shaping device splits the radiation beam into a plurality of radiation fields delivered to the patient 102. Processor 112 in cooperation with beam-shaping device 106 implements a variable feathering method which includes the steps of providing an intensity matrix for the treatment of a patient, the intensity matrix having a plurality of rows and columns for spanning a prescribed radiation field including a prescribed field width. The prescribed width is compared to a maximum field width provided by the radiation treatment system. The intensity matrix is split into a plurality of spatially overlapping intensity submatrices when the prescribed width exceeds the maximum field width, wherein the splitting comprises variably feathering the intensity matrix. Radiotherapy is then provided to the patient 102 using a leaf sequencing method to generate the submatrices.

Abstract translation: 用于递送强度调制辐射治疗（IMRT）的方法和相关系统300使用大尺寸强度调制场的可变羽化场分割。 处理器112控制光束整形装置106，使得光束整形装置将辐射束分成传送到患者102的多个辐射场。 与光束整形装置106协作的处理器112实现可变羽化方法，其包括提供用于治疗患者的强度矩阵的步骤，所述强度矩阵具有多个行和列，用于跨越规定的辐射场，包括规定的 字段宽度。 将规定的宽度与辐射处理系统提供的最大场宽进行比较。 当规定的宽度超过最大场宽时，强度矩阵被分割成多个空间上重叠的强度子矩阵，其中分割包括可变地羽化强度矩阵。 然后使用叶片测序方法向患者102提供放射疗法以产生子矩阵。

公开(公告)号：US07295649B2

公开(公告)日：2007-11-13

申请号：US11249619

申请日：2005-10-13

Applicant: Stanley W. Johnsen

Inventor： Stanley W. Johnsen

IPC: A61N5/10

CPC classification number: A61N5/103 ,  A61N5/1036 ,  A61N5/1042

Abstract: A method of using a radiation system having a multileaf collimator (“MLC”) to adjust for unevenness in the radiation emitted by the system is disclosed. By appropriately controlling the MLC in accordance with the invention the system can be operated without a flattening filter. In addition, the invention allows the system user to vary the radiation beam energy in the course of a single treatment, without the need to use or change flattening filters. A map of the uneven radiation beam intensity in the treatment area is obtained, and the map information is combined with a treatment plan to control movement of the leaves of the MLC such that each area receives the correct radiation dose.

Abstract translation: 公开了一种使用具有多叶准直器（“MLC”）的辐射系统来调整由系统发射的辐射的不均匀性的方法。 通过根据本发明适当地控制MLC，可以在没有平坦化过滤器的情况下操作系统。 此外，本发明允许系统用户在单次处理的过程中改变辐射束能量，而不需要使用或改变平坦化滤光器。 获得处理区域中不均匀辐射束强度的图，并将地图信息与处理计划相结合，以控制MLC叶片的移动，使每个区域接收正确的辐射剂量。

公开(公告)号：US06853705B2

公开(公告)日：2005-02-08

申请号：US10402528

申请日：2003-03-28

Applicant: Sha Chang

Inventor： Sha Chang

IPC: A61N5/10 ,  G21K1/04

CPC classification number: G21K1/04 ,  A61N5/1036 ,  A61N5/1042 ,  G21K1/046

Abstract: In a method for sequentially generating segment fields for use in delivering intensity modulated radiotherapy an input continuous intensity map is generated. A segment field is generated directly from the input intensity map. A residual continuous intensity map is generated that is based on the respective photon fluence contributions from the input intensity map and a fractionally intensity map corresponding to the segment field. These steps are repeated for a number of iterations to generate a like number of additional segment fields and residual maps derived therefrom. In each iteration, the residual map generated in the previous iteration is used as the input intensity map.

Abstract translation: 在用于顺序产生用于递送强度调制放射治疗的分段场的方法中，生成输入连续强度图。 直接从输入强度图生成段字段。 生成残留连续强度图，其基于来自输入强度图的相应光子注量贡献和对应于分段场的分数强度图。 重复这些步骤进行多次迭代以生成相似数量的附加段字段和从其导出的残差映射。 在每次迭代中，将在前一次迭代中生成的残差图用作输入强度图。

公开(公告)号：US20040184578A1

公开(公告)日：2004-09-23

申请号：US10731090

申请日：2003-12-10

Inventor： Hirokazu Nakano

IPC: A61N005/10

CPC classification number: A61N5/103 ,  A61N5/1036 ,  A61N5/1042

Abstract: In an RTP machine, for a series of leaf positions which are generated by a Multileaf-Collimator-Position-Calculation-Unit, a speed limit is established by a Motion-Speed-Limit-Establishing-Unit. Further, a Motion-Display-Unit indicates the area where motion speed exceeds the established speed and/or a Leaf-Position-Correction-Unit controls the area in order to be equal to or less than the established speed limit. Furthermore, a Motion-Acceleration-Calculating-Unit calculates motion acceleration of the multileaf collimator, and the Motion-Display-Unit indicates the area where the calculated motion acceleration exceeds the established limit and/or the Leaf-Position-Correction-Unit controls the area in order to be equal to or less than the established acceleration limit. An interruption of irradiation due to a multileaf collimator positioning error is prevented while the treatment is being conducted by the multileaf collimator motion limit control in radiation therapy such as conformal therapy or others which the multileaf collimator moves in during irradiation.

Abstract translation: 在RTP机器中，对于由多叶准直器位置计算单元生成的一系列叶片位置，速度限制由运动速度限制建立单元建立。 此外，运动显示单元指示运动速度超过建立的速度的区域和/或叶位置校正单元控制该区域以便等于或小于所建立的速度限制。 此外，运动加速计算单元计算多叶准直器的运动加速度，运动显示单元指示计算的运动加速度超过建立的极限的区域和/或叶位置校正单元控制 面积等于或小于已建立的加速度极限。 在通过多叶准直器在放射线治疗中的多叶准直器运动限制控制（诸如保形治疗等）进行治疗时，防止了由于多叶准直器定位误差引起的照射中断，多叶准直器在照射期间移动。

公开(公告)号：US06240161B1

公开(公告)日：2001-05-29

申请号：US08936299

申请日：1997-09-25

Applicant: Ramon Alfredo Siochi

Inventor： Ramon Alfredo Siochi

IPC: G21K508

CPC classification number: A61N5/1042 ,  A61N5/1036

Abstract: A system and method for radiation therapy delivery. The present invention provides for optimizing radiation delivery by accounting for the physical attributes of a beam shielding device (401) when determining an optimal radiation treatment. These include, for example, constraining the optimization engine with realizable positioning of plates and/or collimator leaves. Thus, an optimal set of fields and intensity levels for those fields are chosen.

Abstract translation: 放射治疗递送的系统和方法。 本发明通过在确定最佳辐射治疗时考虑束屏蔽装置（401）的物理属性来提供优化辐射传递。 这些包括例如限制优化引擎与板和/或准直器叶的可实现的定位。 因此，选择这些领域的最佳的一组场和强度水平。

公开(公告)号：US5166531A

公开(公告)日：1992-11-24

申请号：US740164

申请日：1991-08-05

Applicant: Calvin J. Huntzinger

Inventor： Calvin J. Huntzinger

IPC: A61N5/10 ,  G21K1/04

CPC classification number: A61N5/1042 ,  A61N5/1036 ,  A61N5/1045 ,  G21K1/04 ,  G21K1/046

Abstract: A multileaf collimator for use in therapeutic radiology treatment systems for producing irregular shaped radiation fields in order to shield normal tissue or critical organs. A multileaf collimator following the present invention includes leaves designed such that the collimator exhibits penumbra which is minimized and generally uniform for positions that are equidistant from the central axis of the radiation field. The shape of each leaf end includes an asymmetric central portion and a flat portion on either side of the central portion. The central portion is designed such that geometric penumbra and transmission penumbra are equalized. The flat portions on either side of the central portion are coincident with a tangent drawn from the edge of the radiation source to a reference plane when the leaf is in the fully retracted or fully extended positions.

Abstract translation: 一种用于治疗性放射治疗系统的多叶准直器，用于产生不规则形状的辐射场，以屏蔽正常组织或关键器官。 根据本发明的多叶准直器包括被设计成使得准直器表现出最小化并且对于与辐射场的中心轴线等距的位置大致均匀的半影的叶。 每个叶片端部的形状包括不对称的中心部分和位于中心部分两侧的平坦部分。 中心部分被设计成使得几何半影和透射半暗带相等。 当叶片处于完全缩回或完全伸出的位置时，中心部分两侧的平坦部分与从辐射源的边缘到参考平面的切线重合。

公开(公告)号：US12128251B2

公开(公告)日：2024-10-29

申请号：US17663661

申请日：2022-05-16

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Jian Liu ,  Kun Yang ,  Jian Zhang ,  Yanfang Liu ,  Cheng Ni

IPC: A61N5/10 ,  G21K1/04

CPC classification number: A61N5/1045 ,  A61N5/1036 ,  A61N5/1048 ,  A61N5/1081 ,  G21K1/046

Abstract: The present disclosure generally relates to a multi-leaf collimator. The multi-leaf collimator may include a set of leaves installed in a cavity, each leaf of the set of leaves having a length along a first direction. At least a portion of the set of leaves may extend beyond the cavity along the first direction. The set of leaves may be arranged along a second direction, the second direction being different from the first direction. A length of a target leaf of the set of leaves may be less than a length of a reference leaf of the set of leaves. The target leaf may be located in an end portion of the set of leaves along the second direction. The length of the set of leaves may conform to the shape of a maximum therapeutic radiation field.

公开(公告)号：US11896846B2

公开(公告)日：2024-02-13

申请号：US18061991

申请日：2022-12-05

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Johannes Stahl ,  Jonathan Maltz

IPC: A61N5/10

CPC classification number: A61N5/1045 ,  A61N5/1036 ,  A61N5/1049 ,  A61N5/1031 ,  A61N5/1039 ,  A61N5/1077 ,  A61N2005/1032 ,  A61N2005/1035 ,  A61N2005/1041

Abstract: A method for delivering radiation treatment may include defining a preliminary trajectory including a plurality of control points. Each control point may be associated with position parameters of a gantry and a couch. The method may also include generating a treatment plan based on the preliminary trajectory by optimizing an intensity and position parameters of a collimator and MLC leaves for each control point. The method may also include decomposing the treatment plan into a delivery trajectory including the plurality of control points. Each of the plurality of control points may be further associated with the optimized intensity, the optimized position parameters of the collimator and the MLC leaves, an output rate, and a motion parameter of each of the gantry, the couch, the collimator, and the MLC leaves. The method may further include instructing a radiation delivery device to deliver the treatment plan according to the delivery trajectory.

公开(公告)号：US20240047093A1

公开(公告)日：2024-02-08

申请号：US18376531

申请日：2023-10-04

Applicant: Varian Medical Systems International AG

Inventor： Santtu T. Ollila ,  Janne Nord ,  Jarkko Peltola

IPC: G21K1/04 ,  A61N5/10

CPC classification number: G21K1/046 ,  A61N5/1031 ,  A61N5/1045 ,  A61N5/1036

Abstract: A control circuit optimizes a radiation treatment plan for a patient treatment volume using an automatically iterating optimization process that optimizes as a function, at least in part, of predetermined cost functions, wherein at least one of the cost functions favors apertures for the multi-leaf collimation system having local curvature that deviates only minimally from a reference curvature. By one approach the control circuit determines the reference curvature as a function, at least in part, of at least one of setting the reference curvature to a static minimal local curvature, a shape of a projective mapping of the treatment volume onto an isocenter plane, and/or a fluence map associated with an amount of radiation to be administered to the treatment volume from a particular direction. By one approach the control circuit dynamically determines when to employ one or more such cost functions.