公开(公告)号：US20070114434A1

公开(公告)日：2007-05-24

申请号：US11320515

申请日：2005-12-28

Applicant: Sha Chang ,  Otto Zhou

Inventor： Sha Chang ,  Otto Zhou

IPC: G01K1/08

CPC classification number: H01J37/304 ,  G21K5/04 ,  H01J33/02 ,  H01J33/04 ,  H01J37/302 ,  H01J37/317 ,  H01J2201/30469 ,  H01J2237/0635 ,  H01J2237/2004 ,  H01J2237/2006 ,  H01J2237/316

Abstract: Multi-pixel electron microbeam irradiator systems and methods are provided with particular applicability for selectively irradiating predetermined cells or cell locations. A multi-pixel electron microbeam irradiator system can include a plurality of individually addressable electron field emitters sealed in a vacuum. The multi-pixel electron microbeam irradiator system can include an anode comprising one or more electron permeable portions corresponding to the plurality of electron field emitters. Further, the multi-pixel electron microbeam irradiator system can include a controller operable to individually control electron extraction from each of the electron field emitters for selectively irradiating predetermined locations such as cells or cell locations.

Abstract translation: 提供了多像素电子微束照射器系统和方法，其特别适用于选择性地照射预定的细胞或细胞位置。 多像素电子微束照射器系统可以包括在真空中密封的多个可单独寻址的电子场发射器。 多像素电子微束照射器系统可以包括阳极，该阳极包括对应于多个电子场发射体的一个或多个电子透过部分。 此外，多像素电子微束照射器系统可以包括控制器，其可操作以单独地控制来自每个电子场发射器的电子提取，以选择性地照射诸如单元或单元位置的预定位置。

公开(公告)号：US06853705B2

公开(公告)日：2005-02-08

申请号：US10402528

申请日：2003-03-28

Applicant: Sha Chang

Inventor： Sha Chang

IPC: A61N5/10 ,  G21K1/04

CPC classification number: G21K1/04 ,  A61N5/1036 ,  A61N5/1042 ,  G21K1/046

Abstract: In a method for sequentially generating segment fields for use in delivering intensity modulated radiotherapy an input continuous intensity map is generated. A segment field is generated directly from the input intensity map. A residual continuous intensity map is generated that is based on the respective photon fluence contributions from the input intensity map and a fractionally intensity map corresponding to the segment field. These steps are repeated for a number of iterations to generate a like number of additional segment fields and residual maps derived therefrom. In each iteration, the residual map generated in the previous iteration is used as the input intensity map.

Abstract translation: 在用于顺序产生用于递送强度调制放射治疗的分段场的方法中，生成输入连续强度图。 直接从输入强度图生成段字段。 生成残留连续强度图，其基于来自输入强度图的相应光子注量贡献和对应于分段场的分数强度图。 重复这些步骤进行多次迭代以生成相似数量的附加段字段和从其导出的残差映射。 在每次迭代中，将在前一次迭代中生成的残差图用作输入强度图。