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    TRANSAPICAL MINI-INTRODUCER HOMEOSTASIS VALVE AND PUNCH
    103.
    发明申请
    TRANSAPICAL MINI-INTRODUCER HOMEOSTASIS VALVE AND PUNCH 审中-公开
    透视微型引导器家用阀门和PUNCH

    公开(公告)号：US20110282287A1

    公开(公告)日：2011-11-17

    申请号：US13146789

    申请日：2010-01-29

    申请人： Aaron J. Chalekian

    发明人： Aaron J. Chalekian

    IPC分类号： A61B17/34

    CPC分类号： A61B17/3421 ,  A61B17/32053 ,  A61B17/3462 ,  A61B17/3498 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/3425 ,  A61B2017/346 ,  A61B2017/3488

    摘要： An introducer for providing access to the interior of the heart generally includes a valve, a shaft, and a piercing element. The valve has a substantially closed state in the absence of an instrument inside the valve and an open state in the presence of the instrument inside the valve. The shaft has first and second ends. The piercing element is located at the first end of the shaft. The shaft is removably positioned inside the valve in an assembled condition. The valve is dimensioned to receive the instrument therein upon removal of the shaft from the valve.

    摘要翻译： 用于提供进入心脏内部的导引器通常包括阀，轴和穿刺元件。 阀门内没有仪器时，阀门具有基本上关闭的状态，阀门内存在仪器时，阀门处于打开状态。 轴具有第一和第二端。 穿刺元件位于轴的第一端。 轴在组装状态下可拆卸地定位在阀的内部。 该阀的尺寸设计成在从阀上取下轴时接收仪器。

    COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES WITH NATIVE CALCIFIED LEAFLET RETENTION FEATURES
    105.
    发明申请
    COLLAPSIBLE/EXPANDABLE PROSTHETIC HEART VALVES WITH NATIVE CALCIFIED LEAFLET RETENTION FEATURES 有权
    具有先前计算的叶片保持特征的可拆卸/可扩展的前置心脏瓣膜

    公开(公告)号：US20100249923A1

    公开(公告)日：2010-09-30

    申请号：US12733763

    申请日：2008-09-26

    申请人： Yousef F. Alkhatib ,  Michael J. Girard

    发明人： Yousef F. Alkhatib ,  Michael J. Girard

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2230/0006 ,  A61F2230/0054 ,  A61F2230/0069 ,  A61F2230/0076

    摘要： A prosthetic heart valve is circumferentially collapsible for less invasive delivery into a patient. The valve re-expands to operating size at the implant site in the patient. A frame structure of the valve includes restraining structure that can help to push one or more of the patient's native heart valve leaflets radially outwardly so that this native leaflet tissue does not interfere with the operation or service life of the prosthetic valve.

    摘要翻译： 假体心脏瓣膜是周向可折叠的，用于较少侵入性地输送到患者体内。 瓣膜在病人的植入部位重新扩大到操作尺寸。 阀的框架结构包括限制结构，其可以帮助推动病人的天然心脏瓣膜叶片中的一个或多个径向向外，使得该天然小叶组织不会干扰人工瓣膜的操作或使用寿命。

    FIBER-REINFORCED SYNTHETIC SHEETS FOR PROSTHETIC HEART VALVE LEAFLETS
    106.
    发明申请
    FIBER-REINFORCED SYNTHETIC SHEETS FOR PROSTHETIC HEART VALVE LEAFLETS 审中-公开
    纤维增强合成片用于预防心脏瓣膜

    公开(公告)号：US20100249922A1

    公开(公告)日：2010-09-30

    申请号：US12733762

    申请日：2008-09-19

    申请人： XueMei Li ,  Yi-Ren Woo

    发明人： XueMei Li ,  Yi-Ren Woo

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412 ,  A61F2/2415 ,  A61F2250/0018

    摘要： A structure for use as a prosthetic heart valve leaflet includes a two-dimensional array that is made up of one or more fiber strands and that is covered by a web of polymer material to produce a sheet that is impervious to blood. This sheet is stretchable along two axes that lie in the plane of the sheet and that are at an angle to one another. The sheet may be more easily stretched along one of these axes than along the other axis. Along each axis the amount of force required to produce initial increments of stretch may be less than the amount of force required to produce subsequent increments of stretch (i.e., increments of stretch beyond the initial increments).

    摘要翻译： 用作假体心脏瓣膜小叶的结构包括由一根或多根纤维束组成并由聚合物材料的网覆盖以产生不透血液的片的二维阵列。 该片材沿着位于片材平面中并且彼此成角度的两个轴线是可拉伸的。 该片材可以沿着这些轴线沿着另一个轴线更容易地拉伸。 沿着每个轴，产生初始拉伸增量所需的力的量可以小于产生随后的拉伸增量所需的力的量（即，超出初始增量的拉伸增量）。

    Flow system for medical device evaluation and production
    107.
    发明授权
    Flow system for medical device evaluation and production 有权
    医疗器械评估与生产流程系统

    公开(公告)号：US07326564B2

    公开(公告)日：2008-02-05

    申请号：US09789130

    申请日：2001-02-20

    申请人： Beverley I. Lundell ,  Robert L. Meisch ,  John R. Wilson ,  Matthew W. Weston ,  M. William Mirsch, II ,  Kathy J. Grossinger, legal representative

    发明人： Doug A. Page, deceased

    IPC分类号： C12M3/00

    CPC分类号： A61F2/2472 ,  A61F2/022 ,  A61F2/2475 ,  Y10S623/912 ,  Y10S623/915

    摘要： In some embodiments, a flow system includes a medical device mount, fluid and a conduit containing the fluid and medical device mount. The conduit is mounted on an assembly that moves the conduit along with the medical device mount to induce relative motion of the fluid relative to the medical device mount. In preferred embodiments, pulsatile fluid motion is generated. In some embodiments, the fluid includes viable cells. In alternative embodiments, a flow system includes a continuous flow pump connected to a conduit loop having multiple branch conduits downstream from the pump providing alternative paths over a section of the conduit loop. Each branch conduit has a valve controlling flow through the branch. In some embodiments, at least one branch includes a medical device mount.

    摘要翻译： 在一些实施例中，流动系统包括医疗装置支架，流体和容纳流体和医疗装置支架的导管。 导管安装在组件上，该组件与医疗装置安装座一起移动管道以引起流体相对于医疗装置安装座的相对运动。 在优选实施例中，产生脉动流体运动。 在一些实施例中，流体包括活细胞。 在替代实施例中，流动系统包括连接到导管回路的连续流动泵，其具有在泵下游的多个分支管道，在管道环路的一部分上提供替代路径。 每个分支导管都有一个控制流经分支的阀门。 在一些实施例中，至少一个分支包括医疗装置支架。

    Tissue anchor apparatus
    108.
    发明申请
    Tissue anchor apparatus 有权
    组织锚装置

    公开(公告)号：US20060196137A1

    公开(公告)日：2006-09-07

    申请号：US11361197

    申请日：2006-02-23

    申请人： Michael Brenzel ,  Theodore Dale ,  David Costello ,  Paul Hindrichs

    发明人： Michael Brenzel ,  Theodore Dale ,  David Costello ,  Paul Hindrichs

    IPC分类号： F27D1/00

    CPC分类号： A61B19/54 ,  A61B17/32053 ,  A61B90/39 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00623 ,  A61B2017/00986

    摘要： A structure that can be used to provide an anchor in or adjacent to a patient's soft body tissue (rather than bone) includes an annular array of flexible members that extend between two axially spaced but aligned tubular members. The space between the tubular members can be selectively changed to affect the amount by which portions of the flexible members between the tubular member project radially outward relative to the tubular members. When the flexible members project radially out, the structure resists axial movement relative to adjacent tissue and therefore acts as an anchor. When the flexible members do not project radially out, they permit axial movement of the structure through adjacent tissue.

    摘要翻译： 可以用于在患者的软体组织（而不是骨骼）中或邻近提供锚的结构包括在两个轴向间隔开但对准的管状构件之间延伸的柔性构件的环形阵列。 可以选择性地改变管状构件之间的空间以影响管状构件之间的柔性构件的一部分相对于管状构件径向向外突出的量。 当柔性构件径向突出时，结构抵抗相对于相邻组织的轴向运动，因此用作锚固件。 当柔性构件不径向伸出时，它们允许结构体通过相邻组织的轴向运动。

    Conduit for aorta or pulmonary artery replacement
    109.
    发明授权
    Conduit for aorta or pulmonary artery replacement 有权
    导管用于主动脉或肺动脉置换

    公开(公告)号：US07018404B2

    公开(公告)日：2006-03-28

    申请号：US10056774

    申请日：2002-01-24

    申请人： William R. Holmberg ,  Mario Osvaldo Vrandecic Peredo

    发明人： William R. Holmberg ,  Mario Osvaldo Vrandecic Peredo

    IPC分类号： A61F2/06

    CPC分类号： A61F2/06 ,  A61F2/07 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/89 ,  A61F2002/075 ,  A61F2230/0013 ,  A61F2230/0023

    摘要： Prosthetic conduits include biocompatible material formed into a generally cylindrical section and an expanded section connected to the generally cylindrical section. The conduit has a lumen extending through the generally cylindrical section and the expanded section. The biocompatible material may be tissue. The biocompatible material can include one segment or a plurality of segments joined together to form the generally cylindrical section and the expanded section. The prosthetic conduit may include a reinforcement to prevent dilation or collapse of the conduit. The reinforcement can be placed at or near the junction of a generally cylindrical section and an expanded section and/or at other locations along the conduit. The prosthetic conduit may include a prosthetic heart valve. The prosthetic conduit can include tubules to facilitate attachment of coronary arteries to the prosthetic conduit The prosthetic conduit includes two sections that are joined to form the prosthetic conduit.

    摘要翻译： 假体导管包括形成为大致圆柱形部分的生物相容性材料和连接到大致圆柱形部分的扩张部分。 导管具有延伸穿过大致圆柱形部分和扩张部分的内腔。 生物相容性材料可以是组织。 生物相容性材料可以包括连接在一起以形成大致圆柱形部分和扩张部分的一个部分或多个部分。 假体导管可以包括防止导管膨胀或塌陷的加强件。 加强件可以放置在大致圆柱形部分和扩展部分的接合处处和/或沿着导管的其它位置处。 假体导管可以包括假体心脏瓣膜。 假体导管可以包括便于将冠状动脉附着到假体导管的小管。假体导管包括连接以形成假体导管的两个部分。

    Annuloplasty ring holder
    110.
    发明授权
    Annuloplasty ring holder 失效
    瓣环成形术环

    公开(公告)号：US06966924B2

    公开(公告)日：2005-11-22

    申请号：US10222157

    申请日：2002-08-16

    申请人： William R. Holmberg

    发明人： William R. Holmberg

    IPC分类号： A61F2/24 ,  A61F2/06

    CPC分类号： A61F2/2448 ,  A61F2/2466

    摘要： An annuloplasty ring holder includes a first member and a second member. The first and second members are configured to provide relative movement therebetween to engage an annuloplasty ring.

    摘要翻译： 瓣环成形术环形支架包括第一构件和第二构件。 第一和第二构件构造成在它们之间提供相对运动以接合瓣环成形术环。