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101.
公开(公告)号:US10744253B2
公开(公告)日:2020-08-18
申请号:US15666622
申请日:2017-08-02
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
Abstract: The invention relates to systems and methods for adjusting one or more dialysis parameters for delivering a peritoneal dialysis cycle to a patient based on patient or system parameters. The systems and methods include various sensors, flow paths, and processors to adjust the dialysis parameters used to deliver peritoneal dialysis therapy, for a specific peritoneal dialysis cycle. For example, a first peritoneal dialysis cycle can provide data on patient or system parameters that can be used to adjust the dialysis parameters used to deliver a subsequent peritoneal dialysis cycle. One or more peritoneal dialysis cycles are contained in a particular peritoneal dialysis therapy session. Patient parameters can include patient blood pressure; volume of fluid removed; patient goal; blood solute level; effluent solute level; effluent temperature; effluent color or clarity; patient posture; tidal volume remaining in patient; and intraperitoneal pressure.
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公开(公告)号:US20200156044A1
公开(公告)日:2020-05-21
申请号:US16747859
申请日:2020-01-21
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot , Martin T. Gerber
Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate and/or zirconium oxide in reusable sorbent modules. The devices, systems, and methods provide for precision recharging of the zirconium phosphate and/or zirconium oxide to avoid the need of excess recharge solutions. The devices systems and methods also provide for calculation of the volumes of recharge solution needed for fully recharging the zirconium phosphate and zirconium oxide modules.
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公开(公告)号:US20200086309A1
公开(公告)日:2020-03-19
申请号:US16459830
申请日:2019-07-02
Applicant: Medtronic, Inc.
Inventor: Sukalyan Dutta , Bryant J. Pudil , Krishnaraja Nellikunje , Christopher M. Hobot
Abstract: The invention relates to devices, systems, and methods for mixing one or more solutions to generate a recharge solution having specified concentrations of hydroxide and free chlorine for recharging and disinfecting zirconium oxide in reusable sorbent modules. The devices, systems, and methods can generate a recharge solution by a sorbent recharger that is introduced through the sorbent module to recharge the zirconium oxide.
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104.
公开(公告)号:US10537673B2
公开(公告)日:2020-01-21
申请号:US15666604
申请日:2017-08-02
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
Abstract: The invention relates to systems and methods for optimizing a peritoneal dialysate therapy session based on one or more patient or system parameters obtained from a previous peritoneal dialysis therapy session. The systems and methods include various sensors, flow paths, and processors to adjust a peritoneal dialysis prescription for a subsequent therapy session based on data received during or after one or more previous therapy session. For example, a first peritoneal dialysis therapy session can provide data on patient or system parameters that can adjust the dialysis parameters used to deliver a subsequent peritoneal dialysis therapy session. The method can be computer implemented. The system can also include a peritoneal dialysate generation flow path.
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公开(公告)号:US10506933B2
公开(公告)日:2019-12-17
申请号:US15837388
申请日:2017-12-11
Applicant: Medtronic, Inc.
Inventor: Orhan Soykan , VenKatesh R. Manda , Martin T. Gerber , Christopher M. Hobot , Linda L. Ruetz , Carl Schu
IPC: A61B5/0205 , A61B5/0452 , A61B5/00 , A61B5/0488 , A61B5/145 , A61B5/20 , B01D61/24 , B01D61/32 , B01D65/02 , G16H50/30 , A61M1/14 , A61B5/053 , A61M1/16 , A61M1/36
Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
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公开(公告)号:US10343145B2
公开(公告)日:2019-07-09
申请号:US16047245
申请日:2018-07-27
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
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公开(公告)号:US20190038997A1
公开(公告)日:2019-02-07
申请号:US16155035
申请日:2018-10-09
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis using urease pouches. The sorbent cartridge is configured to allow insertion of a urease pouch or injection of a urease solution into the sorbent cartridge containing a urease pouch. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
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公开(公告)号:US20180361355A1
公开(公告)日:2018-12-20
申请号:US15958396
申请日:2018-04-20
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Christopher M. Hobot
Abstract: The invention relates to systems and methods for disinfecting, recharging, and conditioning zirconium oxide in a reusable sorbent module. The systems and methods provide for reuse by recharging and conditioning a zirconium oxide sorbent module after being used in dialysis.
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109.
公开(公告)号:US10099214B2
公开(公告)日:2018-10-16
申请号:US15143494
申请日:2016-04-29
Applicant: Medtronic, Inc.
Inventor: Kanjimpuredathil Muralikrishna Menon , Sujeendran Malayath , Martin T. Gerber , Christopher M. Hobot , Kaustubh R. Patil , Ramkumar Jeyachandran , Sameer Saxena
Abstract: Control logic and processes for monitoring and controlling sorbent rechargers are presented. The control logic and processes use control systems to monitor the rechargers for performance problems and to control the recharging process. Various sensors in communication with the control systems are provided to ensure proper operation.
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公开(公告)号:US10052612B2
公开(公告)日:2018-08-21
申请号:US14722119
申请日:2015-05-26
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
CPC classification number: B01J20/3475 , A61M1/1696 , B01J20/0211 , B01J20/3483 , B01J39/09
Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.
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