公开(公告)号：US20230123024A1

公开(公告)日：2023-04-20

申请号：US17974484

申请日：2022-10-26

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/16 ,  A61M1/28 ,  A61M1/34

Abstract: Systems and methods for managing the pH of a dialysate fluid during hemodialysis therapy. The systems and methods adjust dialysate pH and buffer concentration to generate a predetermined total bicarbonate buffer concentration in a dialysate entering a dialyzer.

公开(公告)号：US11565029B2

公开(公告)日：2023-01-31

申请号：US13836079

申请日：2013-03-15

Applicant: Medtronic, Inc.

Inventor： David B. Lura ,  Thomas E. Meyer ,  Bryant J. Pudil ,  Martin T. Gerber ,  Kenneth J. Collier

IPC: A61M1/16 ,  G01N27/08 ,  A61M1/28

Abstract: A sorbent cartridge that has at least one sensor located within the sorbent cartridge.

公开(公告)号：US20210178365A1

公开(公告)日：2021-06-17

申请号：US17185604

申请日：2021-02-25

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot

IPC: B01J20/34 ,  B01J20/02 ,  A61M1/16 ,  A61L2/18

Abstract: The invention relates to systems and methods for disinfecting, recharging, and conditioning zirconium phosphate in a reusable sorbent module. The systems and methods provide for reuse of a zirconium phosphate sorbent module after dialysis.

公开(公告)号：US10722636B2

公开(公告)日：2020-07-28

申请号：US14887216

申请日：2015-10-19

Applicant: Medtronic, Inc.

Inventor： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

IPC: A61M1/34 ,  A61M1/16

Abstract: Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.

公开(公告)号：US20200038573A1

公开(公告)日：2020-02-06

申请号：US16597086

申请日：2019-10-09

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/16 ,  B01D15/18 ,  B01D15/22 ,  B01J39/12 ,  B01J20/06 ,  B01J20/08 ,  B01J20/20 ,  B01J20/02 ,  B01J20/28

Abstract: Parallel modules for in-line recharging of sorbent materials using alternate duty cycles for a sorbent cartridge. The sorbent cartridge can have two or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein can be recharged.

公开(公告)号：US10543052B2

公开(公告)日：2020-01-28

申请号：US14555393

申请日：2014-11-26

Applicant: Medtronic, Inc.

Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber

IPC: A61M1/16 ,  A61B50/10

Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.

公开(公告)号：US10478545B2

公开(公告)日：2019-11-19

申请号：US15869296

申请日：2018-01-12

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/16 ,  B01D15/18 ,  B01D15/22 ,  B01J39/12 ,  B01J20/06 ,  B01J20/08 ,  B01J20/20 ,  B01J20/02 ,  B01J20/28 ,  G01N30/60

Abstract: Parallel modules for in-line recharging of sorbent materials using alternate duty cycles for a sorbent cartridge. The sorbent cartridge can have two or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein can be recharged.

公开(公告)号：US20190091394A1

公开(公告)日：2019-03-28

申请号：US16202940

申请日：2018-11-28

Applicant: Medtronic, Inc.

Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber

IPC: A61M1/16 ,  A61M1/36 ,  A61M1/34

Abstract: A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session.

公开(公告)号：US20190001303A1

公开(公告)日：2019-01-03

申请号：US16047245

申请日：2018-07-27

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/34 ,  B01J39/09 ,  B01J20/02 ,  A61M1/16

CPC classification number: B01J20/3475 ,  A61M1/1696 ,  B01J20/0211 ,  B01J20/3483 ,  B01J39/09

Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer or module of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include a fluid source containing at least one recharging fluid, wherein the fluid source is fluidly connectable to at least one rechargeable sorbent module for use in sorbent dialysis in a fluid flow path. The methods and apparatuses include passing a single solution through the zirconium phosphate for ion exchanges, resulting in zirconium phosphate to maintain a substantially consistent pH in a dialysate used during dialysis.

公开(公告)号：US10159957B2

公开(公告)日：2018-12-25

申请号：US15364251

申请日：2016-11-29

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot

IPC: B01J20/34 ,  B01J20/02 ,  A61M1/16 ,  B01J39/09

Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate in a reusable zirconium phosphate sorbent module. The devices, systems, and methods provide for customization of the zirconium phosphate effluent pH based on the needs of the user and system. The devices systems and methods also provide for calculation of the volumes of recharge solution needed for fully recharging the zirconium phosphate modules.