公开(公告)号：US10076283B2

公开(公告)日：2018-09-18

申请号：US14539437

申请日：2014-11-12

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  Christopher M. Hobot ,  Martin T. Gerber ,  VenKatesh R. Manda

IPC: A61M37/00 ,  A61B5/00 ,  A61B5/0205 ,  A61M1/34 ,  A61M1/16 ,  A61M1/28 ,  A61B5/021 ,  A61B5/024 ,  A61B5/046 ,  A61B5/053 ,  A61B5/08 ,  A61B5/1455 ,  A61B5/20 ,  G06F19/00 ,  G16H50/20 ,  G16H50/50

CPC classification number: A61B5/7246 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/02405 ,  A61B5/046 ,  A61B5/053 ,  A61B5/08 ,  A61B5/14552 ,  A61B5/201 ,  A61B5/4806 ,  A61B5/4848 ,  A61B5/4875 ,  A61B5/7264 ,  A61M1/1603 ,  A61M1/282 ,  A61M1/3403 ,  A61M2205/3523 ,  G06F19/00 ,  G06F19/3481 ,  G16H20/40 ,  G16H50/20 ,  G16H50/50

Abstract: A system and method for determining the amount of fluid to be removed from a dialysis patient is disclosed. The system utilizes sensors and a computer. The computer obtains the input parameters from the sensors, along with information added directly by the user, and performs a forward algorithm to determine a recommended change in patient fluid level. As fluid is removed, the effect of the removal on the parameters is detected by the sensors and re-transmitted back to the computer. The computer then performs a backward algorithm to refine the variables used in the forward algorithm and obtain more accurate results. The system and method provide for changing the amount of fluid removed from the patient based on the results of the algorithm and the data received from the sensors.

公开(公告)号：US20180021501A1

公开(公告)日：2018-01-25

申请号：US15723676

申请日：2017-10-03

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot ,  David B. Lura ,  Thomas E. Meyer ,  VenKatesh R. Manda

IPC: A61M1/28

Abstract: The invention relates to devices, systems, and methods for generating a peritoneal dialysate having specified concentrations of one or more solutes. The devices, systems and methods use conductivity sensors, flow meters, and composition sensors to control addition of osmotic agents and ion concentrates into a peritoneal dialysate generation flow path.

公开(公告)号：US20170281846A1

公开(公告)日：2017-10-05

申请号：US15478569

申请日：2017-04-04

Applicant: Medtronic, Inc.

Inventor： VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/28 ,  A61K31/19 ,  A61K31/715 ,  A61K33/14 ,  A61L2/10 ,  A61K31/7004

CPC classification number: A61M1/282 ,  A61K31/19 ,  A61K31/7004 ,  A61K31/715 ,  A61K33/14 ,  A61L2/10 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/1686 ,  A61M1/28 ,  A61M1/287 ,  A61M2205/3331 ,  A61M2205/3337 ,  A61M2205/3368 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/75 ,  A61M2205/7518 ,  A61M2209/084 ,  A61M2209/10 ,  C02F1/283 ,  C02F1/325 ,  C02F1/42 ,  C02F1/441 ,  C02F1/442 ,  C02F1/444 ,  C02F2303/04

Abstract: Systems and methods of generating peritoneal dialysate and using the peritoneal dialysate with an integrated cycler are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare peritoneal dialysate from source water and infuse the prepared peritoneal dialysate into a patient with an integrated cycler. Optional dialysate storage containers are provided for storage of the peritoneal dialysate prior to use.

公开(公告)号：US20150359954A1

公开(公告)日：2015-12-17

申请号：US14838112

申请日：2015-08-27

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Daniel Bloomberg ,  David B. Lura ,  VenKatesh R. Manda

IPC: A61M1/16

CPC classification number: A61M1/36 ,  A61M1/3681 ,  A61M2205/3375 ,  A61M2205/6009 ,  A61M2205/75 ,  G06K19/077

Abstract: A dialysis authentication and management system comprising at least one dialysis component having at least one authentication component affixed thereon. The dialysis component can be any one of a dialyzer, sorbent cartridge, recharger or any other dialysis component. The authentication component can be selected from the group of a radio-frequency identification marker, a bar code, a one-wire security component, and a wireless authentication component. The authentication system can ensure that all components used are in proper usable condition and/or certified. The system can also manage the recharging of rechargeable components, and optionally manage dialysis therapy.

Abstract translation: 一种透析认证和管理系统，包括至少一个其上贴有至少一个认证部件的透析部件。 透析组分可以是透析器，吸附剂盒，充电器或任何其它透析组分中的任何一种。 可以从射频识别标记，条形码，单线安全组件和无线认证组件的组中选择认证组件。 认证系统可以确保使用的所有组件都处于适当的可用状态和/或认证。 该系统还可以管理可再充电部件的充电，并可选择进行透析治疗。

公开(公告)号：US10967112B2

公开(公告)日：2021-04-06

申请号：US15693535

申请日：2017-09-01

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  SuPing Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  A61M1/34 ,  A61M1/36 ,  A61M1/00 ,  A61M1/14 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/026 ,  A61M1/28 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  A61B5/0537 ,  G06F19/00

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

公开(公告)号：US20210008265A1

公开(公告)日：2021-01-14

申请号：US17034250

申请日：2020-09-28

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  SuPing Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  A61M1/34 ,  A61M1/36 ,  A61M1/00 ,  A61M1/14 ,  B01D61/00 ,  B01D61/32 ,  A61B5/0295 ,  A61B5/053 ,  B01D65/02 ,  A61B5/026 ,  A61M1/28

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

公开(公告)号：US10335534B2

公开(公告)日：2019-07-02

申请号：US15333267

申请日：2016-10-25

Applicant: Medtronic, Inc.

Inventor： Amy Roettger ,  VenKatesh R. Manda ,  John Burnes ,  Rebecca Poindexter ,  Martin T. Gerber

IPC: A61M1/36 ,  G16H50/30 ,  A61M1/34 ,  A61B5/00 ,  A61B5/145 ,  G06F19/00 ,  A61M1/16

Abstract: Systems and methods are provided for determining an estimated risk of arrhythmia during or after dialysis based on changes in serum potassium concentration of a patient and an amount of fluid removed from the patient during dialysis. The systems and methods allow for a determination of a risk that arrhythmia will occur due to the changes in potassium and fluid volume of a patient during dialysis, and for optimizing a dialysis prescription in order to minimize the risk of arrhythmia.

公开(公告)号：US09968721B2

公开(公告)日：2018-05-15

申请号：US14554338

申请日：2014-11-26

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  Suping Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M37/00 ,  A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  A61B5/026 ,  A61B5/053 ,  A61M1/34 ,  B01D65/02 ,  A61M1/00 ,  A61B5/0295 ,  A61M1/14 ,  B01D61/00 ,  B01D61/32 ,  A61M1/36 ,  A61M1/28

CPC classification number: A61M1/1603 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/4875 ,  A61B5/6866 ,  A61B5/7282 ,  A61B2560/0223 ,  A61M1/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1613 ,  A61M1/28 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/342 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3672 ,  A61M2202/0498 ,  A61M2205/04 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/70 ,  A61M2230/00 ,  A61M2230/005 ,  A61M2230/06 ,  A61M2230/20 ,  A61M2230/207 ,  A61M2230/208 ,  A61M2230/65 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  B01D2321/12 ,  B01D2321/40 ,  G06F19/00

Abstract: A method includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The method may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. The system includes a blood fluid removal device and control electronics configured to set the initial fluid removal volume and rate prescription. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.

公开(公告)号：US20170281845A1

公开(公告)日：2017-10-05

申请号：US15478562

申请日：2017-04-04

Applicant: Medtronic, Inc.

Inventor： VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61K33/14 ,  A61L2/00 ,  A61K33/06 ,  A61K33/00 ,  A61K31/716 ,  A61K31/7004 ,  A61K31/19

CPC classification number: A61M1/282 ,  A61K31/19 ,  A61K31/7004 ,  A61K31/716 ,  A61K33/00 ,  A61K33/06 ,  A61K33/14 ,  A61L2/0017 ,  A61L2/0023 ,  A61L2/0047 ,  A61L2202/21 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/1686 ,  A61M1/28 ,  A61M1/287 ,  A61M2205/3337 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/75 ,  A61M2205/7518 ,  A61M2209/10 ,  C02F1/001 ,  C02F1/02 ,  C02F1/28 ,  C02F1/283 ,  C02F1/325 ,  C02F1/42 ,  C02F1/441 ,  C02F1/442 ,  C02F1/444 ,  C02F2303/04

Abstract: Systems and methods of generating peritoneal dialysate are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare a bolus of peritoneal dialysate from source water for use with an non-integrated cycler.

公开(公告)号：US20170000936A1

公开(公告)日：2017-01-05

申请号：US15263582

申请日：2016-09-13

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/16

CPC classification number: A61M1/1601 ,  A61B5/0205 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/0452 ,  A61B5/145 ,  A61B5/686 ,  A61B2505/07 ,  A61M1/14 ,  A61M2205/18 ,  A61M2205/3553 ,  A61M2205/3584 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/06 ,  A61M2230/20 ,  A61M2230/208 ,  A61M2230/30 ,  A61M2230/63 ,  G06F19/00

Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.

Abstract translation: 描述用于监测来自被检体的身体的电信号的医疗监视装置。 医疗监视装置监测源自受试者的心脏周期的电信号，并将每个心动周期与时间指数相关联。 医疗监测装置应用前向计算程序来产生指示受试者的高钾血症，低钾血症或心律失常的风险评分。 医疗监视装置可以基于从受试者获得的临床数据来调整前向计算程序。