公开(公告)号：US11679186B2

公开(公告)日：2023-06-20

申请号：US17201569

申请日：2021-03-15

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  G01N21/78 ,  G01N21/80 ,  G01N21/77

CPC classification number: A61M1/28 ,  A61B5/14507 ,  A61B5/6866 ,  A61M1/1601 ,  A61M1/1609 ,  A61M1/287 ,  A61M2205/3306 ,  A61M2205/3324 ,  A61M2205/50 ,  A61M2205/75 ,  G01N21/78 ,  G01N21/80 ,  G01N2021/7773 ,  G01N2021/7783 ,  G01N2021/7786 ,  G01N2800/06

Abstract: The invention relates to a testing system and related methods for detecting peritonitis or infection in peritoneal dialysate removed from a patient. The testing system can include a fluid sensor apparatus in a fluid line of a peritoneal dialysis cycler through which spent peritoneal dialysate can be pumped. The fluid sensor apparatus can detect one or more markers associated with peritonitis or infection.

公开(公告)号：US20220176026A1

公开(公告)日：2022-06-09

申请号：US17541736

申请日：2021-12-03

Applicant: Medtronic, Inc. ,  Bellco S.r.l.

Inventor： Vijaya Kumar Parari ,  Christopher M. Hobot ,  Kaustubh R. Patil ,  Fabrizio Puviani ,  Daniel Hahn

IPC: A61M1/28 ,  F16L1/06

Abstract: A flexible pipe routing accessory for routing a flexible tube between a preparator and an automatic cycler of a peritoneal dialysis system, comprising: a guide pipe through which the flexible tube is to be routed; a guide wire configured to pass through the guide pipe and selectively connect to the flexible tube; and a winding mechanism configured to move the guide wire through the guide pipe.

公开(公告)号：US11219880B2

公开(公告)日：2022-01-11

申请号：US16747859

申请日：2020-01-21

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: B01J20/06 ,  B01J20/34 ,  B01J20/02 ,  A61M1/16 ,  B01J39/09

Abstract: The invention relates to devices, systems, and methods for recharging zirconium phosphate and/or zirconium oxide in reusable sorbent modules. The devices, systems, and methods provide for precision recharging of the zirconium phosphate and/or zirconium oxide to avoid the need of excess recharge solutions. The devices systems and methods also provide for calculation of the volumes of recharge solution needed for fully recharging the zirconium phosphate and zirconium oxide modules.

公开(公告)号：US20210275990A1

公开(公告)日：2021-09-09

申请号：US17330758

申请日：2021-05-26

Applicant: Medtronic, Inc

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  A61M1/16 ,  B01J20/22 ,  B01J20/06 ,  B01J20/02 ,  B01J20/20

Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.

公开(公告)号：US10994064B2

公开(公告)日：2021-05-04

申请号：US15666614

申请日：2017-08-02

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16

Abstract: The invention relates to systems and methods for sensing fluid characteristics of peritoneal dialysate infused into and removed from a patient during treatment. The systems and methods include sensors, processors, and flow paths for determining patient health based on the fluid characteristics of the peritoneal dialysate. The system can be a peritoneal dialysis cycler which can include an infusion line; an effluent line; at least one pump positioned in the infusion and/or effluent line; and at least one sensor fluidly connected to the effluent line. The sensor can be at least one of a flow sensor, an ion selective electrode, a pH sensor, a pressure sensor, a refractive index sensor, and a temperature sensor. The method can include infusing peritoneal dialysate through an infusion line; removing peritoneal dialysate through an effluent line; and determining at least one fluid characteristic of the peritoneal dialysate in the effluent line.

公开(公告)号：US10980930B2

公开(公告)日：2021-04-20

申请号：US15219242

申请日：2016-07-25

Applicant: Medtronic, Inc.

Inventor： David B. Lura ,  Christopher M. Hobot ,  Martin T. Gerber ,  Thomas E. Meyer

IPC: A61M1/16 ,  A61M1/26 ,  A61M39/22 ,  A61M39/12

Abstract: The invention relates to fluid flow paths and fluid connectors for use with detachable containers that can be seated in an infusate caddy for use in a dialysis machine. The detachable containers can contain infusates or other solutes or materials such as disinfectants or cleaners, and can be conveniently seated in the infusate caddy. The detachable containers can be removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed. The fluid path and fluid connectors of the present invention provide the required fluid fittings, valve arrangements, pumps, and paddle assemblies for using the infusate caddy.

公开(公告)号：US20200179583A1

公开(公告)日：2020-06-11

申请号：US16691686

申请日：2019-11-22

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/28

Abstract: The invention relates to devices, systems, and methods for performing a precision or personalized Peritoneal Dialysis (PD) therapy session or cycle based on dialysis adequacy measurements in patients undergoing peritoneal dialysis treatment. The settings for the precision peritoneal dialysis therapy session can be obtained using one or more flow sensors and one or more uremic solute sensors that measure the uremic solute concentration and volume of the peritoneal dialysate removed from the patient. The desired dialysis adequacy for a specific patient, group of patients, or class of patients, can then be calculated based on the measured peritoneal dialysate concentration and volume. Using the calculated dialysis adequacy, the system and methods can then set one or more peritoneal dialysis parameters for subsequent cycles or sessions.

公开(公告)号：US20200061269A1

公开(公告)日：2020-02-27

申请号：US16458336

申请日：2019-07-01

Applicant: Medtronic, Inc.

Inventor： Sukalyan Dutta ,  Bryant J. Pudil ,  Krishnaraja Nellikunje ,  Christopher M. Hobot ,  Kanjimpuredathil Muralikrishna Menon

IPC: A61M1/16 ,  B01J20/02

Abstract: The invention relates to devices, systems, and methods for mixing one or more solutions to generate a recharge solution having specified concentrations of a sodium salt and acid for recharging and disinfecting zirconium phosphate in reusable sorbent modules. The devices, systems, and methods can generate a recharge solution by a sorbent recharger that is introduced through the sorbent module to recharge and to disinfect the zirconium phosphate.

公开(公告)号：US20200054807A1

公开(公告)日：2020-02-20

申请号：US16435976

申请日：2019-06-10

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/16

Abstract: The invention relates to devices, systems, and methods for preforming a precision dialysis therapy session based on an analysis of an effluent from a zirconium phosphate sorbent module during an ammonium removal process. The settings for the precision dialysis therapy session can be obtained by estimating a patient's physiological state, such as BUN level, based on the analysis of the effluent for a particular sorbent module linked to a particular patient.

公开(公告)号：US20190291079A1

公开(公告)日：2019-09-26

申请号：US16435772

申请日：2019-06-10

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/28 ,  A61M1/16

Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.