Abstract:
A method of data loading for large information warehouses includes performing checkpointing concurrently with data loading into an information warehouse, the checkpointing ensuring consistency among multiple tables; and recovering from a failure in the data loading using the checkpointing. A method is also disclosed for performing versioning concurrently with data loading into an information warehouse. The versioning method enables processing undo and redo operations of the data loading between a later version and a previous version. Data load failure recovery is performed without starting a data load from the beginning but rather from a latest checkpoint for data loading at an information warehouse level using a checkpoint process characterized by a state transition diagram having a multiplicity of states; and tracking state transitions among the states using a system state table.
Abstract:
In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular grafts, for example. In one embodiment, an ultraviolet (UV) resin made from a diacrylated biodegradable oligomer is molded into a flexible scaffold having cavities and/or channels. Channel/cavity size may be on the order of micrometers and/or nanometers, and thus the walls may have high aspect ratios. Smooth muscle cells may be deposited in the channels and because of the high aspect ratios, the cells may align along the channels/cavities as confluence is reached.
Abstract:
A system is provided for estimating an operational parameter of a first engine, the first engine including a rotatable crankshaft. The system includes a model for estimating the operational parameter of the first engine as a function of instantaneous crankshaft speed at a plurality of angular positions of the crankshaft of the first engine. The model is developed, at least partially, based upon operational data from a second engine having a rotatable crankshaft. A sensor is operable to determine values representative of the instantaneous crankshaft speed of the first engine, at a plurality of angular positions of the crankshaft of the first engine. A modifier is operable to modify at least some of the representative values to, at least partially, calibrate out differences between the first and second engines that may cause variations in instantaneous crankshaft speed. The modified values are input to the model.
Abstract:
Methods for identifying inducers and inhibitors of programmed cell death in a cell-free system are described. The methods exploit the finding that programmed cell death is accompanied by shutdown of cellular protein synthesis and by phosphorylation of eIF-2.alpha. and that the dephosphorylation of eIF-2.alpha. prevents the shutdown of protein synthesis.