Prostaglandins E and anti ulcers containing same
    112.
    发明授权
    Prostaglandins E and anti ulcers containing same 失效
    前列腺素E和含有相同的抗溃疡

    公开(公告)号:US5428062A

    公开(公告)日:1995-06-27

    申请号:US53487

    申请日:1993-04-28

    IPC分类号: C07C405/00 A61K31/557

    CPC分类号: C07C405/00

    摘要: The novel 13,14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro-15-keto-prostaglandins E of the invention have an advatage that they have none of side effects which prostaglandin E intrinsically has, or can remarakably reduce such effects of the prostaglandin E.Therefore, the novel 13,14-dihydro-15-keto prostaglandins E of the invention are effective for animal and human use for treatment and prevention of ulcers, such as duodenal ulcer and gastric ulcer.

    摘要翻译: 本发明的新型13,14-二氢-15-酮前列腺素E对溃疡具有显着的预防作用。 此外,本发明的新型13,14-二氢-15-酮前列腺素E具有前列腺素E本身具有的副作用,或者可以再度降低前列腺素E的作用的优点。因此,该小说 本发明的13,14-二氢-15-酮前列腺素E对于动物和人类用于治疗和预防溃疡如十二指肠溃疡和胃溃疡是有效的。

    Prostaglandins E and anti ulcers containing same
    113.
    发明授权
    Prostaglandins E and anti ulcers containing same 失效
    前列腺素E和含有相同的抗溃疡

    公开(公告)号:US5284858A

    公开(公告)日:1994-02-08

    申请号:US925220

    申请日:1992-08-06

    CPC分类号: C07C405/00

    摘要: The novel 13, 14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro-15-ketoprostaglandins E of the invention have an advatage that they have none of side effects which prostaglandin E intrinsically has, or can remarakably reduce such effects of the prostaglandin E.Therefore, the novel 13, 14-dihydro-15-keto prostaglandins E of the invention are effective for animal and human use for treatment and prevention of ulcers, such as duodenal ulcer and gastric ulcer.

    摘要翻译: 本发明的新型13,14-二氢-15-酮前列腺素E对溃疡具有显着的预防作用。 此外,本发明的新型13,14-二氢-15-酮基前列腺素E具有前列腺素E本身具有的副作用,或者可以再度降低前列腺素E的效果的优点。因此, 本发明的14-二氢-15-酮前列腺素E对于动物和人类用于治疗和预防溃疡如十二指肠溃疡和胃溃疡是有效的。

    Hypersphyxia-causing methods
    114.
    发明授权
    Hypersphyxia-causing methods 失效
    造成高血糖的方法

    公开(公告)号:US5169863A

    公开(公告)日:1992-12-08

    申请号:US672758

    申请日:1991-03-22

    IPC分类号: A61K31/557

    CPC分类号: A61K31/557

    摘要: This invention provides a hypersphyxia-causing composition containing 15-keto-PGEs esters separated from any substantial activity such as decrease of blood pressure.The present invention provides a hypersphyxia-causing composition effective to recovery of blood pressure, and heart rate in e.g. hemmorrhage shock, or hyperventilation, which comprises 15-keto PGEs esters.

    摘要翻译: 本发明提供含有与任何基本活性(如降低血压)分离的15-酮-PGE酯的含有高钠血症的组合物。 本发明提供了有效恢复血压的高窒息组合物, 出血性休克或过度通气,其包含15-酮PGE酯。

    Process for producing aromatic hydroxycarboxylic acids
    118.
    发明授权
    Process for producing aromatic hydroxycarboxylic acids 失效
    制备芳族羟基羧酸的方法

    公开(公告)号:US4780567A

    公开(公告)日:1988-10-25

    申请号:US887037

    申请日:1986-07-01

    CPC分类号: C07C51/15

    摘要: This invention provides a process for selectively producing aromatic hydroxycarboxylic acids, which comprises subjecting a liquid mixture consisting of a polycyclic aromatic hydrocarbon, an alkali metal salt of an aromatic hydroxy compound and a free aromatic hydroxy compound to a reaction with carbon dioxide. The process permits the production of the intended product with enhanced selectivity.

    摘要翻译: PCT No.PCT / JP85 / 00626 Sec。 371日期:1986年7月1日 102(e)日期1986年7月1日PCT提交1985年11月9日PCT公布。 出版物WO86 / 02924 日本特愿1986年5月22日。本发明提供选择性地制备芳族羟基羧酸的方法,其包括将由多环芳烃,芳族羟基化合物的碱金属盐和游离芳族羟基化合物组成的液体混合物与 二氧化碳。 该方法允许以增强的选择性生产预期的产品。

    Liquid bactericide for foods and food processing machines or utensils,
employing a synergistic mixture of ethyl alcohol, an organic acid and
phosphoric acid
    119.
    发明授权
    Liquid bactericide for foods and food processing machines or utensils, employing a synergistic mixture of ethyl alcohol, an organic acid and phosphoric acid 失效
    用于食品和食品加工机器或器具的液体杀菌剂,采用乙醇,有机酸和磷酸的协同混合物

    公开(公告)号:US4647458A

    公开(公告)日:1987-03-03

    申请号:US581366

    申请日:1984-02-14

    摘要: A liquid bactericide for foods and food processing machines or utensils, said bactericide comprising as active ingredients 98.0 to 2.3% (W/V) of ethyl alcohol, 1.0 to 96.7% (W/V) of an organic acid selected from the group consisting of lactic acid, acetic acid, citric acid, tartaric acid, gluconic acid, malic acid, ascorbic acid and phytic acid and 1.0 to 96.7% (W/V) of phosphoric acid; said bactericide being capable of sterilizing within 30 seconds when used in an aqueous solution, such that the concentration of active ingredients in solution consists of 14 to 1% (W/V) of ethyl alcohol, 13.0 to 0.3% (W/V) of said organic acid and 0.7 to 0.03% (W/V) of phosphoric acid.

    摘要翻译: 一种用于食品和食品加工机器或器具的液体杀菌剂,所述杀菌剂包含98.0至2.3%(W / V)乙醇的活性成分,1.0至96.7%(W / V)的选自以下的有机酸: 乳酸,乙酸,柠檬酸,酒石酸,葡萄糖酸,苹果酸,抗坏血酸和植酸和1.0〜96.7%(W / V)的磷酸; 所述杀菌剂在水溶液中使用时可在30秒内灭菌,使得溶液中活性成分的浓度由14至1%(W / V)的乙醇组成,13.0至0.3%(W / V)的 所述有机酸和0.7〜0.03%(W / V)的磷酸。