MACHINE FOR DRESSING THE EDGES AND OUTER SURFACES OF FLAT WORKPIECES
    111.
    发明申请
    MACHINE FOR DRESSING THE EDGES AND OUTER SURFACES OF FLAT WORKPIECES 有权
    用于连接平面工件的边缘和外表面的机器

    公开(公告)号:US20080280545A1

    公开(公告)日:2008-11-13

    申请号:US12117135

    申请日:2008-05-08

    申请人: Georg Weber

    发明人: Georg Weber

    IPC分类号: B24B9/00

    CPC分类号: B24B41/047

    摘要: In a machine for processing the edges and outer surfaces of flat workpieces, including a machine frame with a workpiece support surface 12 and at least one dressing head 14 with a work tool carrier, which work tool carrier is rotatably supported on the machine frame for rotation about a first axis perpendicular to the workpiece support surface 12 and is driven by a drive, and which work tool carrier carries at least two work tools 32 rotatably supported eccentrically to the first axis on the work tool carrier each for rotation about a second axis perpendicular to the workpiece support surface 12, and each of which tools is connected with a planet gear 44 which stands in meshing drive engagement with a sun gear 26 coaxial to the first axis so that each circulating work tool carrier defines an effective circle 46 of its work tools 32, with at least two dressing heads 14 being so arranged next to one another that the effective circles 46 of their work tools 32 overlap, with the movement of the work tool carriers of neighboring dressing heads 14 being so controlled that the work tools 42 arranged on their work tool carriers are displaced from one another in the circulating direction.

    摘要翻译: 在用于加工平面工件的边缘和外表面的机器中,包括具有工件支撑表面12的机架和至少一个具有工作工具托架的修整头14,该工作工具托架可旋转地支撑在机架上用于旋转 围绕垂直于工件支撑表面12的第一轴线并且由驱动器驱动,并且该工作工具承载件承载至少两个工作工具32,该工作工具32可旋转地支撑在工作工具承载件上的第一轴线上,每个工作工具32围绕第二轴线垂直 到工件支撑表面12,并且每个工具与行星齿轮44连接,行星齿轮44与与第一轴线同轴的太阳轮26啮合驱动接合,使得每个循环的作业工具托架限定其工作的有效圆46 具有至少两个修整头14的工具32彼此相邻布置,使得其工作工具32的有效圆46与运动重叠 相邻修整头14的作业工具托架被控制使得布置在其工作工具托架上的作业工具42在循环方向上彼此偏离。

    Osteopontin-based cancer therapies
    113.
    发明申请
    Osteopontin-based cancer therapies 审中-公开
    基于骨桥蛋白的癌症治疗

    公开(公告)号:US20060252684A1

    公开(公告)日:2006-11-09

    申请号:US11272528

    申请日:2005-11-10

    申请人: Georg Weber

    发明人: Georg Weber

    IPC分类号: A61K48/00 A61K38/54

    CPC分类号: C07K14/52 A61K38/00

    摘要: The invention relates to therapies for treating cancer patients by targeting the osteopontin isoforms OPN-b and OPN-c. Osteopontin is a cytokine that is essential for cellular immunity, particularly through its full length form, OPN-a. OPN-b and OPN-c are splice variants that lack exons 5 and 4, respectively, of the protein's six translated exons. The invention provides methods for treating cancer patients with therapeutics that inhibit or degrade the OPN-b or OPN-c isoforms specifically, thereby leaving the innocuous OPN-a form intact and available to perform its normal functions in the cell.

    摘要翻译: 本发明涉及通过靶向骨桥蛋白亚型OPN-b和OPN-c治疗癌症患者的疗法。 骨桥蛋白是细胞免疫所必需的细胞因子,特别是通过其全长形式,OPN-α。 OPN-b和OPN-c是分别缺乏蛋白质六个翻译外显子的外显子5和4的剪接变体。 本发明提供用于治疗具有抑制或降解OPN-b或OPN-c同种型的治疗剂的癌症患者的方法,从而使无害的OPN-a形式完整且可用于在细胞中执行其正常功能。

    Sanding station for a belt sanding machine
    114.
    发明授权
    Sanding station for a belt sanding machine 有权
    砂带台砂带机砂带机

    公开(公告)号:US07052380B2

    公开(公告)日:2006-05-30

    申请号:US10914099

    申请日:2004-08-07

    申请人: Georg Weber

    发明人: Georg Weber

    IPC分类号: B24B21/06

    CPC分类号: B24B21/06

    摘要: A sanding station for a belt sanding machine includes at least an endless sanding belt guided over deflection rollers and a pressure segment belt circulating within the sanding belt for pressing the sanding belt against the workpiece. The running direction of the pressure segment belt is oriented transversely to the running direction of the sanding belt.

    摘要翻译: 用于带式砂光机的打磨站至少包括在偏转辊上引导的环形砂带和在砂带内循环的压力分段带,用于将砂带压靠在工件上。 压力段带的运行方向横向于砂带的运行方向。

    Pressure relief valve with a spring-loaded membrane closing body
    116.
    发明授权
    Pressure relief valve with a spring-loaded membrane closing body 失效
    减压阀带有弹簧加载膜封闭体

    公开(公告)号:US06789569B2

    公开(公告)日:2004-09-14

    申请号:US10181645

    申请日:2002-07-18

    IPC分类号: F16K1704

    摘要: The pressure relief valve has a spring pressure-loaded diaphragm closing body (13), which in the closed position sealingly engages on a centrally positioned valve seating surface (10) surrounding a first valve opening (8). Its spring pressure loading takes place by means of a counterpressure body (13) positioned centrally over it. The valve seating surface (10) is surrounded by a channel-like valve chamber (11) in the valve housing body (2) and on which is provided on the overpressure side at least one second valve opening (9). To be able to dissipate high overpressures, the counterpressure body (30) is surrounded by a diaphragm support ring (17) held on the valve housing (6) and which has a circumferential recess (19), whose depth measured perpendicular to the diaphragm closing body (13) determines the maximum deflection of said body (13), so that when the valve is completely opened the diaphragm closing body (13) is supported in an area between the valve seating surface (10) and its outer edge.

    摘要翻译: 减压阀具有弹簧压力加载的膜片关闭体(13),其在关闭位置密封地接合在围绕第一阀开口(8)的位于中心的阀座表面(10)上。 其弹簧压力负载通过位于其上方的反压体(13)进行。 阀座表面(10)被阀壳体(2)中的通道状阀室(11)包围,并且在超压侧上设置有至少一个第二阀开口(9)。 为了能够消散高的超压,反压体(30)由保持在阀壳体(6)上的隔膜支撑环(17)包围,并且具有周向凹部(19),其垂直于隔膜的深度测量 主体(13)确定所述主体(13)的最大偏转,使得当阀完全打开时,隔膜关闭体(13)被支撑在阀座表面(10)和其外边缘之间的区域中。

    Mixture delivery device for internal combustion engines
    118.
    发明授权
    Mixture delivery device for internal combustion engines 失效
    内燃机混合输送装置

    公开(公告)号:US6041594A

    公开(公告)日:2000-03-28

    申请号:US100322

    申请日:1998-06-19

    摘要: A mixture delivery device for introducing a reducing agent into an exhaust gas system of an internal combustion engine in which, a urea-water solution is introduced into a region of the exhaust gas system, upstream of a catalytic converter, through the introduction of compressed air, in order to bring about the reduction of nitrogen oxides in the exhaust gas of the internal combustion engine. The mixture delivery device includes a mixture carrying line, with a first section that extends laterally to the exhaust gas flow and a second section that extends concentrically to a longitudinal axis of the exhaust gas system. The mixture carrying line is inserted into the exhaust gas system, wherein the urea-water solution is injected in the form of a cone into the exhaust gas upstream of the catalytic converter via blow-out openings embodied radially in the second section. The mixture delivery device is particularly suited for delivering a urea-water solution upstream of the catalytic converter in the exhaust gas system of a mixture compressing, spontaneously igniting internal combustion engine.

    摘要翻译: 一种用于将还原剂引入到内燃机的排气系统中的混合物输送装置,其中尿素 - 水溶液通过引入压缩空气引入到排气系统的区域中,在催化转化器的上游 ,以便实现内燃机的排气中的氮氧化物的还原。 混合物输送装置包括混合物输送管线,第一部分横向延伸到废气流,第二部分同心地延伸到废气系统的纵向轴线。 将混合物输送管线插入废气系统中,其中尿素 - 水溶液以锥形的形式通过在第二部分中径向放出的吹出开口注入到催化转化器上游的废气中。 混合物输送装置特别适用于在压缩自发点燃内燃机的混合气体的排气系统中将催化转化器上游的尿素 - 水溶液输送。