公开(公告)号：US20190211378A1

公开(公告)日：2019-07-11

申请号：US16084965

申请日：2016-09-09

Applicant: UBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid ,  Siavosh Rezvan Behbahani

IPC: C12Q1/689

CPC classification number: C12Q1/689 ,  C12Q2600/158 ,  C12Q2600/16 ,  G16B20/00 ,  G16B30/00 ,  G16B40/00 ,  G16H50/20 ,  G16H50/50

Abstract: Methods, compositions, and systems are provided for detecting one or more a cognition health issues by characterizing the microbiome of an individual, monitoring such effects, and/or determining, displaying, or promoting a therapy for the cognition health issue. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and/or functional diversity datasets. Methods, compositions, and systems are also provided for generating a characterization model and/or therapy model for insomnia issues, light sleep issues, headache issues, sinusitis issues, and poor concentration issues.

公开(公告)号：US10347368B2

公开(公告)日：2019-07-09

申请号：US15848824

申请日：2017-12-20

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G01N33/48 ,  G16H10/40 ,  C12Q1/6883 ,  G06F19/00 ,  G16B40/00 ,  G16B50/00 ,  G16H50/20 ,  H01L27/32 ,  H01L51/00 ,  H01L51/52 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating a cardiovascular disease condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cardiovascular disease condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cardiovascular disease condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10347366B2

公开(公告)日：2019-07-09

申请号：US15816041

申请日：2017-11-17

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G01N33/48 ,  G16H10/40 ,  C12Q1/6883 ,  G06F19/00 ,  G16B40/00 ,  G16B50/00 ,  G16H50/20 ,  H01L27/32 ,  H01L51/00 ,  H01L51/52 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating a cardiovascular disease condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cardiovascular disease condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cardiovascular disease condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10347362B2

公开(公告)日：2019-07-09

申请号：US15655640

申请日：2017-07-20

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G01N33/48 ,  G16B30/00 ,  C12Q1/689 ,  G06F19/00 ,  G16B5/00 ,  G16B40/00 ,  G16B50/00 ,  G16H50/20 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the endocrine system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the endocrine system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10346588B2

公开(公告)日：2019-07-09

申请号：US15606909

申请日：2017-05-26

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

IPC: G01N33/48 ,  G06F19/00 ,  G16B50/00 ,  C12Q1/68 ,  C12Q1/6883 ,  C12Q1/689 ,  G16H50/20 ,  G16H20/10 ,  G16B99/00 ,  G16B5/00 ,  G06G7/58

Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10340045B2

公开(公告)日：2019-07-02

申请号：US15644628

申请日：2017-07-07

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

IPC: G01N33/48 ,  G16H50/20 ,  G06F19/00 ,  G16B35/00 ,  G16B40/00 ,  G16B50/00 ,  G16C20/60 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10332635B2

公开(公告)日：2019-06-25

申请号：US15645049

申请日：2017-07-10

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

IPC: G01N33/48 ,  G16H50/20 ,  G06F19/00 ,  G16B35/00 ,  G16B40/00 ,  G16B50/00 ,  G16C20/60 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10331857B2

公开(公告)日：2019-06-25

申请号：US15621152

申请日：2017-06-13

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

IPC: G01N33/48 ,  G06F19/00 ,  G16B50/00 ,  C12Q1/68 ,  C12Q1/6883 ,  C12Q1/689 ,  G16H50/20 ,  G16H20/10 ,  G16B99/00 ,  G16B5/00 ,  G06G7/58

Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10327642B2

公开(公告)日：2019-06-25

申请号：US15815636

申请日：2017-11-16

Applicant: uBiome, Inc

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G01N33/48 ,  A61B5/00 ,  C12Q1/689 ,  G06F19/00 ,  G16B40/00 ,  G16B50/00 ,  G16H50/20 ,  G16H50/80 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

公开(公告)号：US10327641B2

公开(公告)日：2019-06-25

申请号：US15815365

申请日：2017-11-16

Applicant: uBiome, Inc

Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman

IPC: G01N33/48 ,  A61B5/00 ,  C12Q1/689 ,  G06F19/00 ,  G16B40/00 ,  G16B50/00 ,  G16H50/20 ,  G16H50/80 ,  G06G7/58

Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.