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131.发明申请公开(公告)号：US20200000902A1
公开(公告)日：2020-01-02
申请号：US16554139
申请日：2019-08-28
Applicant: Immatics Biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC: A61K39/00 , C07K7/08 , C12N15/115 , C12N5/0783 , C07K14/71 , C07K14/725 , C07K16/28 , C12Q1/6886 , C07K16/18 , G01N33/574 , C07K14/47 , C07K16/30 , C07K7/06 , C07K14/72 , C12N9/12 , C07K16/38 , C07K14/81 , C07K16/40 , C12N9/02 , C07K14/705 , G16B25/00
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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132.发明申请公开(公告)号：US20190315832A1
公开(公告)日：2019-10-17
申请号：US16413192
申请日：2019-05-15
Applicant: Immatics Biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC: C07K14/74 , G01N33/574 , C07K14/635 , C07K14/47 , C07K16/28 , C07K14/725 , C12N5/0783 , A61K39/00 , C12Q1/6886
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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133.发明申请公开(公告)号：US20190241630A1
公开(公告)日：2019-08-08
申请号：US16388915
申请日：2019-04-19
Applicant: Immatics Biotechnologies GmbH
Inventor： Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH
IPC: C07K14/47 , C07K14/725 , A61P35/00 , C12N5/0783 , C07K16/30 , C12N15/10 , G01N33/574 , A61K39/00 , C12N15/115 , C07K14/74
CPC classification number: C07K14/4748 , A61K39/0011 , A61K39/001102 , A61K2039/5158 , A61K2039/572 , A61P35/00 , C07K14/7051 , C07K14/70539 , C07K16/2818 , C07K16/30 , C07K2319/00 , C12N5/0638 , C12N15/1062 , C12N15/115 , C12N2501/50 , G01N33/57492
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20190169233A1
公开(公告)日：2019-06-06
申请号：US16274491
申请日：2019-02-13
Applicant: IMMATICS BIOTECHNOLOGIES GMBH
Inventor： Toni WEINSCHENK , Steffen WALTER , Jens FRITSCHE , Colette SONG , Harpreet SINGH
Abstract: A method of treating a patient who has glioblastoma and/or gastric cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize cells in the patient that aberrantly express a peptide. A pharmaceutical composition contains activated T cells that selectively recognize cells in a patient that aberrantly express a peptide, and a pharmaceutically acceptable carrier, in which the T cells bind to the peptide in a complex with an MHC class I molecule, and the composition is for treating the patient who has glioblastoma and/or gastric cancer. A method of treating a patient who has glioblastoma and/or gastric cancer includes administering to said patient a composition comprising a peptide in the form of a pharmaceutically acceptable salt, thereby inducing a T-cell response to the glioblastoma and/or gastric cancer.
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135.发明申请公开(公告)号：US20180251516A1
公开(公告)日：2018-09-06
申请号：US15965305
申请日：2018-04-27
Applicant: immatics biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC: C07K14/74 , C12Q1/6886 , A61K39/00 , C07K14/47 , C07K14/635 , C07K14/725 , C12N5/0783 , G01N33/574 , C07K16/28 , A61K38/00
CPC classification number: C07K14/70539 , A61K38/00 , A61K39/00 , A61K39/0011 , C07K14/4748 , C07K14/635 , C07K14/7051 , C07K16/2833 , C07K2319/70 , C12N5/0638 , C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , G01N33/57484
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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Patent Agency Ranking
136.发明申请公开(公告)号：US20180064796A1
公开(公告)日：2018-03-08
申请号：US15799495
申请日：2017-10-31
Applicant: immatics biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH , Colette SONG
IPC: A61K39/00 , C07K16/30 , C12N5/0783 , C12N15/115 , C07K16/28 , G06F19/20 , C07K14/74 , C07K16/18 , C07K14/47 , A61K35/12 , C07K14/705
CPC classification number: A61K39/0011 , A61K35/17 , A61K2035/124 , A61K2039/505 , A61K2039/5158 , A61K2039/572 , C07K14/4748 , C07K14/705 , C07K14/70539 , C07K16/18 , C07K16/2833 , C07K16/3038 , C07K2317/73 , C07K2317/76 , C07K2319/33 , C07K2319/55 , C12N5/0636 , C12N15/115 , C12N2310/16 , G06F19/20
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20170320913A1
公开(公告)日：2017-11-09
申请号：US15639165
申请日：2017-06-30
Applicant: IMMATICS BIOTECHNOLOGIES GMBH
Inventor： Toni WEINSCHENK , Steffen WALTER , Jens FRITSCHE , Colette SONG , Harpreet SINGH
CPC classification number: C07K7/08 , A61K38/1709 , A61K39/0011 , C07K7/06 , C12N5/0638 , C12N9/6491 , C12Y304/24065
Abstract: A method of treating a patient who has glioblastoma and/or gastric cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize cells in the patient that aberrantly express a peptide. A pharmaceutical composition contains activated T cells that selectively recognize cells in a patient that aberrantly express a peptide, and a pharmaceutically acceptable carrier, in which the T cells bind to the peptide in a complex with an MHC class I molecule, and the composition is for treating the patient who has glioblastoma and/or gastric cancer. A method of treating a patient who has glioblastoma and/or gastric cancer includes administering to said patient a composition comprising a peptide in the form of a pharmaceutically acceptable salt, thereby inducing a T-cell response to the glioblastoma and/or gastric cancer.
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138.发明申请公开(公告)号：US20170189513A1
公开(公告)日：2017-07-06
申请号：US15375058
申请日：2016-12-09
Applicant: immatics biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC: A61K39/00 , C07K14/72 , C12N15/115 , C07K16/40 , C07K16/28 , C07K14/725 , C12N9/12 , C12N5/0783
CPC classification number: A61K39/0011 , A61K35/17 , A61K38/00 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K14/7051 , C07K14/71 , C07K14/721 , C07K14/8135 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K16/2869 , C07K16/30 , C07K16/38 , C07K16/40 , C07K2317/34 , C07K2317/76 , C07K2319/40 , C12N5/0636 , C12N5/0638 , C12N9/0091 , C12N9/1264 , C12N15/115 , C12N2310/16 , C12N2502/11 , C12Q1/6886 , C12Q2600/156 , C12Y116/01 , C12Y207/07031 , G01N33/57484 , G01N2333/47 , G06F19/20
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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139.发明申请公开(公告)号：US20170189512A1
公开(公告)日：2017-07-06
申请号：US15375051
申请日：2016-12-09
Applicant: immatics biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC: A61K39/00 , C12N15/115 , C07K16/40 , C07K14/725 , C12N9/12 , C12N5/0783
CPC classification number: A61K39/0011 , A61K35/17 , A61K38/00 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K14/7051 , C07K14/71 , C07K14/721 , C07K14/8135 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K16/2869 , C07K16/30 , C07K16/38 , C07K16/40 , C07K2317/34 , C07K2317/76 , C07K2319/40 , C12N5/0636 , C12N5/0638 , C12N9/0091 , C12N9/1264 , C12N15/115 , C12N2310/16 , C12N2502/11 , C12Q1/6886 , C12Q2600/156 , C12Y116/01 , C12Y207/07031 , G01N33/57484 , G01N2333/47 , G06F19/20
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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140.发明申请公开(公告)号：US20170189506A1
公开(公告)日：2017-07-06
申请号：US15374882
申请日：2016-12-09
Applicant: immatics biotechnologies GmbH
Inventor： Andrea MAHR , Toni WEINSCHENK , Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC: A61K39/00 , C12N15/115 , C07K16/30 , C07K14/725 , C07K14/47 , C12N5/0783
CPC classification number: A61K39/0011 , A61K35/17 , A61K38/00 , A61K2039/5158 , A61K2039/572 , C07K7/06 , C07K7/08 , C07K14/47 , C07K14/4748 , C07K14/705 , C07K14/7051 , C07K14/71 , C07K14/721 , C07K14/8135 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K16/2869 , C07K16/30 , C07K16/38 , C07K16/40 , C07K2317/34 , C07K2317/76 , C07K2319/40 , C12N5/0636 , C12N5/0638 , C12N9/0091 , C12N9/1264 , C12N15/115 , C12N2310/16 , C12N2502/11 , C12Q1/6886 , C12Q2600/156 , C12Y116/01 , C12Y207/07031 , G01N33/57484 , G01N2333/47 , G06F19/20
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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