公开(公告)号：US20220026323A1

公开(公告)日：2022-01-27

申请号：US17289282

申请日：2019-10-30

Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM ,  OSAKA UNIVERSITY

Inventor： Takao YASUI ,  Yoshinobu BABA ,  Hirotaka KOGA

IPC: G01N1/40 ,  C12N15/10 ,  D04H1/425

Abstract: The present invention provides a novel miRNA extraction method and a method for analyzing miRNA extracted by using said miRNA extraction method. According to the present invention, provided is, for example, a method for extracting miRNA from extracellular vesicles in a sample solution, by using a device capable of capturing extracellular vesicles, the miRNA extraction method comprising: an extracellular vesicle capturing step for capturing extracellular vesicles in a sample solution onto a device by bringing the sample solution and the device in contact with each other; and a miRNA extraction step for homogenizing the extracellular vesicles by bringing the device having captured the extracellular vesicles in contact with a homogenization liquid for extracellular vesicles to extract miRNA from the extracellular vesicle into the homogenization liquid.

公开(公告)号：US20220024842A1

公开(公告)日：2022-01-27

申请号：US17428097

申请日：2019-09-17

Applicant: OSAKA UNIVERSITY ,  DAICEL CORPORATION

Inventor： Tomoo MIZUGAKI ,  Kiyotomi KANEDA ,  Yasuteru KAJIKAWA ,  Yuuichirou HIRAI

IPC: C07C29/149 ,  B01J23/652 ,  B01J21/06

Abstract: The present invention provides a method for selectively producing an alcohol by efficiently hydrogenating a lactone. The present invention is a method for producing an alcohol, the method including hydrogenating a substrate lactone represented by Formula (1), in the presence of a catalyst described below, to produce an alcohol that is represented by Formula (2).
In the formulae, R represents a divalent hydrocarbon group which may have a hydroxyl group.
The catalyst comprises: metal species including M1 and M2; and a support supporting the metal species, and wherein M1 is rhodium, platinum, ruthenium, iridium, or palladium; M2 is tin, vanadium, molybdenum, tungsten, or rhenium; and the support is hydroxyapatite, fluorapatite, hydrotalcite, or ZrO2.

公开(公告)号：US11216578B2

公开(公告)日：2022-01-04

申请号：US16473286

申请日：2017-12-26

Applicant: OSAKA UNIVERSITY

Inventor： Atsuko Miyaji

IPC: G06F21/62 ,  G16H10/60 ,  G06F16/9535 ,  G06F16/11 ,  G06Q50/22

Abstract: According to a data analysis method by which time required for data analysis is shortened and practicality is improved, a client terminal requests institution terminals to perform analysis of a matching attribute; each of the institution terminals encrypts an element belonging to the matching attribute within a database and sends the converted data to an outsource terminal; the outsource terminal integrates the plurality of converted data sent from the institution terminals and sends the integrated converted data to the institution terminals; and each of the institution terminals compares each matching attribute of a plurality of the elements within the database of the institution terminal against the integrated converted data, thereby identifying, as a common element, an element associated with the matching attribute and held in common by the institution terminals.

公开(公告)号：US20210404945A1

公开(公告)日：2021-12-30

申请号：US17336720

申请日：2021-06-02

Applicant: The University of Tokyo ,  Osaka University

Inventor： Sadao Ota ,  Ryoichi Horisaki ,  Kazuki Hashimoto

IPC: G01N21/01 ,  G01B11/00 ,  G01N21/64 ,  H03M7/30 ,  G01N21/53 ,  G01N21/59

Abstract: Any one or both of an optical system with a structured lighting pattern and a structured detecting system having a plurality of regions with different optical characteristics are used. In addition, optical signals from an object to be observed through one or a small number of pixel detectors are detected while changing relative positions between the object to be observed and any one of the optical system and the detecting system, time series signal infoimation of the optical signals are obtained, and an image associated with an object to be observed from the time series signal information is reconstructed.

公开(公告)号：US20210399228A1

公开(公告)日：2021-12-23

申请号：US17288949

申请日：2019-10-25

Applicant: Osaka University ,  ISHIHARA SANGYO KAISHA, LTD.

Inventor： Yutaka Ie ,  Takuji Seo ,  Shreyam Chatterjee ,  Taichi Moriyama ,  Syun Kudo

IPC: H01L51/00 ,  C07D513/22 ,  C09K11/06 ,  C07D498/22 ,  C07D517/22 ,  C07D495/22

Abstract: Provided are a compound having an excellent semiconductor property and a method for producing the compound, an intermediate of the compound and a method for producing the intermediate, and an organic semiconductor material and an organic semiconductor device each obtained with use of the organic semiconductor material.
A compound represented by general formula (2): where: A1 and A2 are CM1 or N, and M1 is H or the like; J1 and J2 are each independently a skeleton giving an electron donating property or an electron accepting property; and X1 and X2 are where: M2 to M4 are H or the like, and M3 and M4 may be bonded to each other to form a ring.

公开(公告)号：US20210379877A1

公开(公告)日：2021-12-09

申请号：US17285637

申请日：2019-10-15

Applicant: OSAKA UNIVERSITY ,  TOYODA GOSEI CO., LTD.

Inventor： Shinji TAKANO ,  Koya MATSUNO ,  Yoshinori NAGAMORI ,  Akira HARADA ,  Yoshinori TAKASHIMA ,  Motofumi OSAKI ,  Katsunari INOUE

IPC: B32B27/28 ,  C08J7/12 ,  B32B27/08 ,  B32B37/10 ,  B32B37/06

Abstract: To provide a polyrotaxane composite formed body produced by strong bonding between a crosslinked polyrotaxane formed body and an elastomer formed body without intervention of an adhesive.
Provided is a method for producing a polyrotaxane composite formed body, the method including subjecting a surface of a crosslinked polyrotaxane formed body and a surface of an elastomer formed body to plasma treatment, and pressure joining the treated surfaces together, to thereby bond the formed bodies. Also provided is a polyrotaxane composite formed body including a crosslinked polyrotaxane formed body and an elastomer formed body, wherein these formed bodies are directly bonded together without being intermingled with each other in the absence of an adhesive layer between the formed bodies, an oxygen-rich layer is present between the bonding surfaces of the formed bodies, and the formed bodies exhibit a peel strength of 1 N/m or more.

公开(公告)号：US20210361549A1

公开(公告)日：2021-11-25

申请号：US16641775

申请日：2019-03-18

Applicant: MANDOM CORPORATION ,  OSAKA UNIVERSITY

Inventor： Kie Nakashima ,  Ryuichiro Kurata ,  Fumitaka Fujita ,  Fumihiro Okada

IPC: A61K8/365 ,  A61K8/37 ,  A61K8/60 ,  A61Q15/00

Abstract: Provided is an antiperspirant which serves to control secretion of sweat secreted from sweat glands and is capable of doing so by acting on sweat glands without closing sweat pores, the antiperspirant containing, as an active ingredient to control secretion of sweat secreted from sweat glands, at least one type of pentacyclic compound selected from the group consisting of compounds represented by formula (I): and derivatives thereof, and compounds represented by formula (VII): and derivatives thereof.

公开(公告)号：US20210338798A1

公开(公告)日：2021-11-04

申请号：US16316186

申请日：2017-07-11

Applicant: The Research Foundation for Microbial Diseases of Osaka University

Inventor： Takao Fujimoto ,  Junji Fujita

IPC: A61K39/145 ,  C12N7/00

Abstract: Provided is a method of producing reassortant influenza virus containing an antigenic protein of the first influenza virus strain, the method including the following steps: 1) a step of irradiating the first influenza virus strain with ultraviolet light in such an irradiation dose that the first influenza virus strain has initial infection ability and loses or is reduced in virus growth potential; 2) a step of infecting a host with the first influenza virus strain and the second influenza virus strain; 3) a step of culturing the host infected with the first influenza virus strain and the second influenza virus strain, to obtain culture product; 4) a step of inactivating influenza virus strain having an antigenic protein of the second influenza virus strain in the culture product obtained in the step 3); and 5) a step of collecting reassortant influenza virus after the step 4).

公开(公告)号：US11151997B2

公开(公告)日：2021-10-19

申请号：US16491280

申请日：2018-01-26

Applicant: NIPPON TELEGRAPH AND TELEPHONE CORPORATION ,  OSAKA UNIVERSITY

Inventor： Hiroaki Sugiyama ,  Hiromi Narimatsu ,  Yuichiro Yoshikawa ,  Takamasa Iio ,  Tsunehiro Arimoto ,  Hiroshi Ishiguro

IPC: G10L15/22 ,  G10L15/18 ,  G10L15/30

Abstract: It is an object of the present invention to provide a dialog technique that can reduce a user's uncomfortable feeling. A dialog system 100 is a dialog system that conducts a dialog with the user, the dialog system including a presentation part 50 that presents an action to fill a gap between a user utterance and a response utterance of the dialog system, after it is estimated or determined that the user utterance has ended or after a predicted time at which the user utterance ends, and before the dialog system makes a response utterance to the user utterance.

公开(公告)号：US11150392B2

公开(公告)日：2021-10-19

申请号：US16463676

申请日：2017-11-15

Applicant: OSAKA UNIVERSITY

Inventor： Hiroyuki Yoshida

IPC: G02B5/30 ,  G02B5/18 ,  G02F1/1335 ,  G02F1/1337 ,  G02F1/29

Abstract: An optical element 1 includes a first layer (A1) and a second layer (A2) that faces the first layer (A1). The first layer (A1) includes a plurality of first structural bodies (B1) that each have optical anisotropy. In reflection of light entering from the first layer (A1), the second layer (A2) reflects the light while maintaining a polarization state of the light at incidence and at the reflection. The first layer (A1) changes, according to directions of orientation of the first structural bodies (B1), a phase of the light from a phase at incidence to the first layer (A1) from outside of the first layer (A1) to a phase at output from the first layer (A1) toward the second layer (A2). The first layer (A1) changes the phase of the light from a phase at incidence to the first layer (A1) from the second layer (A2) to a phase at output from the first layer (A1) toward the outside of the first layer (A1) according to the directions of orientation of the first structural bodies (B1).