公开(公告)号：US20210068720A1

公开(公告)日：2021-03-11

申请号：US16951759

申请日：2020-11-18

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20210045665A1

公开(公告)日：2021-02-18

申请号：US17088381

申请日：2020-11-03

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, JR. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10918315B2

公开(公告)日：2021-02-16

申请号：US16924117

申请日：2020-07-08

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Steve Masterson ,  John Nolting ,  James R. Petisce ,  Jack Pryor ,  Sean Saint ,  Peter C. Simpson ,  Vance Swanson ,  Matthew D. Wightlin

IPC: A61B5/1486 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/1468 ,  A61B5/145 ,  A61B5/05 ,  A61B5/00 ,  A61B5/15 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20210000394A1

公开(公告)日：2021-01-07

申请号：US17026852

申请日：2020-09-21

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US10827956B2

公开(公告)日：2020-11-10

申请号：US16790435

申请日：2020-02-13

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Peter C. Simpson ,  Matthew D. Wightlin ,  Steve Masterson ,  James R. Petisce ,  John Nolting ,  Jack Pryor ,  Sean Saint ,  Vance Swanson ,  James H. Brauker ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  Aarthi Mahalingam

IPC: A61B5/1468 ,  A61B5/1486 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20200343941A1

公开(公告)日：2020-10-29

申请号：US16925233

申请日：2020-07-09

Applicant: DexCom, Inc.

Inventor： Thomas Miller ,  Mark Dervaes ,  Phong Lieu ,  Peter C. Simpson ,  Shawn Larvenz ,  Jacob S. Leach ,  Sebastian Bohm

IPC: H04B5/00 ,  H04W76/14 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  G01N27/327 ,  H04W12/06 ,  H04W4/80 ,  H04W52/02

Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.

公开(公告)号：US20200337618A1

公开(公告)日：2020-10-29

申请号：US16924117

申请日：2020-07-08

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, JR. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10791928B2

公开(公告)日：2020-10-06

申请号：US16796830

申请日：2020-02-20

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Mark C. Brister ,  Monica A. Rixman ,  Kum Ming Woo ,  Lisa Nguyen ,  Seth R. Brunner ,  Arthur Chee ,  Melissa A. Nicholas ,  Matthew D. Wightlin ,  Jack Pryor ,  Dubravka Markovic

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1473

Abstract: Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

公开(公告)号：US20200281511A1

公开(公告)日：2020-09-10

申请号：US16882334

申请日：2020-05-22

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Sebastian Bohm ,  Robert J. Boock ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  A61B5/1473 ,  A61B5/1459 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486

Abstract: Disclosed herein are devices, systems, and methods for a continuous analyte sensor, such as a continuous glucose sensor. In certain embodiments disclosed herein, various in vivo properties of the sensor's surroundings can be measured. In some embodiments, the measured properties can be used to identify a physiological response or condition in the body. This information can then be used by a patient, doctor, or system to respond appropriately to the identified condition.

公开(公告)号：US20200245917A1

公开(公告)日：2020-08-06

申请号：US16857107

申请日：2020-04-23

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Sebastian Bohm ,  James H. Brauker ,  Paul V. Neale

IPC: A61B5/1486 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/00

Abstract: A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.