公开(公告)号：US20210000394A1

公开(公告)日：2021-01-07

申请号：US17026852

申请日：2020-09-21

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US10827958B2

公开(公告)日：2020-11-10

申请号：US15362955

申请日：2016-11-29

Applicant: DexCom, Inc.

Inventor： William Biederman ,  Timothy Stowe

IPC: A61B5/00 ,  A61B5/1473 ,  A61B5/145

Abstract: In some examples, a sensor holder device is described. The sensor holder device may include a rigid body, a set legs attached to the rigid body, a sensor guiding structure, a sensor retaining structure, and an electrical trace. The sensor retaining structure may be sized to accommodate a sensor wire. The electrical trace may extend proximate the sensor retaining structure and along one of the legs.

公开(公告)号：US10827956B2

公开(公告)日：2020-11-10

申请号：US16790435

申请日：2020-02-13

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Peter C. Simpson ,  Matthew D. Wightlin ,  Steve Masterson ,  James R. Petisce ,  John Nolting ,  Jack Pryor ,  Sean Saint ,  Vance Swanson ,  James H. Brauker ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  Aarthi Mahalingam

IPC: A61B5/1468 ,  A61B5/1486 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10791928B2

公开(公告)日：2020-10-06

申请号：US16796830

申请日：2020-02-20

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Mark C. Brister ,  Monica A. Rixman ,  Kum Ming Woo ,  Lisa Nguyen ,  Seth R. Brunner ,  Arthur Chee ,  Melissa A. Nicholas ,  Matthew D. Wightlin ,  Jack Pryor ,  Dubravka Markovic

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1473

Abstract: Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

公开(公告)号：US10725652B2

公开(公告)日：2020-07-28

申请号：US15391366

申请日：2016-12-27

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Eric Cohen ,  Arturo Garcia ,  Katherine Yerre Koehler ,  Michael Robert Mensinger ,  Eli Reihman ,  Brian Christopher Smith ,  Peter Hedlund ,  Esteban Cabrera, Jr.

IPC: A61B5/00 ,  G06F3/0488 ,  G08B21/04 ,  A61B5/145 ,  G06F1/16 ,  H04W4/80

Abstract: A system, a method, and a computer program product for providing wearable continuous blood glucose monitoring. In some embodiments, there is provided a method that includes receiving, at a smartwatch, an alert representative of a glucose state of a host-patient coupled to a glucose sensor; detecting, at the smartwatch, a predetermined action indicative of a request to generate a glance view providing an indication of the glucose state of the host-patient; and presenting, at the smartwatch and in response to the detecting, the glance view providing the indication of the glucose state of the host-patient.

公开(公告)号：US10709332B2

公开(公告)日：2020-07-14

申请号：US16543404

申请日：2019-08-16

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Jack Pryor ,  John Nolting ,  Jacob S. Leach ,  Luis Pestana ,  Nelson Quintana ,  Vance Swanson ,  Paul V. Goode, Jr. ,  James Patrick Thrower

IPC: A61B5/00 ,  A61B5/15 ,  A61B5/145 ,  A61B5/1486 ,  G16Z99/00 ,  A61B5/1473 ,  G06F19/00

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10702193B2

公开(公告)日：2020-07-07

申请号：US16742848

申请日：2020-01-14

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker

IPC: A61B5/05 ,  A61B5/145 ,  A61B5/1486 ,  C12Q1/00 ,  B33Y80/00 ,  A61B5/00

Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

公开(公告)号：US10595900B2

公开(公告)日：2020-03-24

申请号：US15298721

申请日：2016-10-20

Applicant: DexCom, Inc.

Inventor： Ryan Everett Schoonmaker ,  Jennifer Blackwell ,  Christopher M. Davis ,  David DeRenzy ,  Eric Gobrecht ,  Jason Halac ,  Jonathan Hughes ,  Kathleen Suzanne Hurst ,  Randall Scott Koplin ,  Phong Lieu ,  Kyle Neuser ,  Todd Andrew Newhouse ,  Jack Pryor ,  Peter C. Simpson ,  Maria Noel Brown Wells ,  Justen Deering England ,  Stefanie Lynn Mah ,  Leonard Darius Barbod ,  Jillian K. Allen ,  Michael J. Estes ,  Philip Thomas Pupa ,  Timothy Joseph Goldsmith ,  Kyle Tinnell Keller

IPC: A61B5/05 ,  A61B17/34 ,  A61B5/00 ,  A61B5/145 ,  A61B17/00

Abstract: The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing. Systems and methods according to present principles allow for such steps to occur without significant loss of spring force, and without deleterious effects such as seal slingshotting.

公开(公告)号：US20200085355A1

公开(公告)日：2020-03-19

申请号：US16691252

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1495 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1473

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20200085354A1

公开(公告)日：2020-03-19

申请号：US16690977

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, JR. ,  James H. Brauker

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1495

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.