-
公开(公告)号：US20140205565A1
公开(公告)日：2014-07-24
申请号：US14223909
申请日：2014-03-24
申请人： Robert G. Matheny
发明人： Robert G. Matheny
CPC分类号： A61L27/3873 , A61K9/0019 , A61K31/22 , A61K31/366 , A61K31/40 , A61K31/4418 , A61K31/505 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/18 , A61K38/1825 , A61K38/1841 , A61K38/20 , A61K38/39 , A61K45/06 , A61K48/00 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/40 , A61L27/54 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30 , A61K2300/00
摘要： A method of retarding cellular senescence comprising (i) providing an extracellular matrix (ECM) composition comprising ECM from an adolescent tissue source, the ECM comprising an exogenously added cytokine, and (ii) administering ECM composition to an organ with cells exhibiting cellular senescence, wherein, the cytokine interacts with at least one molecule in the ECM composition and modulates ROS production of the cells, whereby, the cellular senescence is abated.
摘要翻译： 一种延缓细胞衰老的方法，包括（i）从青少年组织来源提供包含ECM的细胞外基质（ECM）组合物，所述ECM包含外源加入的细胞因子，和（ii）向具有细胞衰老细胞的器官施用ECM组合物， 其中，细胞因子与ECM组合物中的至少一个分子相互作用并调节细胞的ROS产生，从而减少细胞衰老。
-
公开(公告)号：US08785198B1
公开(公告)日：2014-07-22
申请号：US14038974
申请日：2013-09-27
发明人： Robert G Matheny
IPC分类号： C12N5/00 , A61F2/00 , A61K35/37 , A61K35/38 , C12N5/071 , C12N5/02 , A61K38/18 , A61K31/7088 , A61K31/726
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US08784891B2
公开(公告)日：2014-07-22
申请号：US13732805
申请日：2013-01-02
申请人： Francis Law Group
发明人： Robert G Matheny
IPC分类号： A61K48/00 , A61L27/36 , A61L27/40 , A61K38/17 , A61K35/54 , A61L27/38 , A61K35/38 , A61K35/34 , A61K38/18 , A61K9/00
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US08753886B1
公开(公告)日：2014-06-17
申请号：US13875073
申请日：2013-05-01
申请人： Robert G Matheny
发明人： Robert G Matheny
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US08735155B1
公开(公告)日：2014-05-27
申请号：US14038992
申请日：2013-09-27
申请人： Robert G Matheny
发明人： Robert G Matheny
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US08734841B2
公开(公告)日：2014-05-27
申请号：US13732685
申请日：2013-01-02
发明人： Robert G Matheny
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US20130129690A1
公开(公告)日：2013-05-23
申请号：US13732731
申请日：2013-01-02
申请人： Francis Law Group
发明人： Robert G. Matheny
IPC分类号： A61L27/38
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US20130116198A1
公开(公告)日：2013-05-09
申请号：US13732718
申请日：2013-01-02
申请人： Robert G. Matheny
发明人： Robert G. Matheny
IPC分类号： A61L27/36
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号：US20070014873A1
公开(公告)日：2007-01-18
申请号：US11448931
申请日：2006-06-06
申请人： Robert Matheny
发明人： Robert Matheny
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition can also have an extracellular matrix scaffold component of any formulation, then including also added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. Methods for regenerating defective or absent myocardium apply a composition to a site of myocardium in need of regeneration using a delivery mode appropriate for the particular formulation.
-
公开(公告)号：US20070014872A1
公开(公告)日：2007-01-18
申请号：US11448355
申请日：2006-06-06
申请人： Robert Matheny , Beecher Lewis
发明人： Robert Matheny , Beecher Lewis
CPC分类号： A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要： Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition can also have an extracellular matrix scaffold component of any formulation, then including also added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. Methods for regenerating defective or absent myocardium apply a composition to a site of myocardium in need of regeneration using a delivery mode appropriate for the particular formulation.
-
-
-
-
-
-
-
-
-
搜索结果
172 条记录 (耗时 0.027 秒)
