-
公开(公告)号:US20130123348A1
公开(公告)日:2013-05-16
申请号:US13732700
申请日:2013-01-02
申请人: Francis Law Group
发明人: Robert G. Matheny
IPC分类号: A61L27/36
CPC分类号: A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号:US08734842B2
公开(公告)日:2014-05-27
申请号:US13732754
申请日:2013-01-02
申请人: Francis Law Group
发明人: Robert G Matheny
CPC分类号: A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号:US08709076B1
公开(公告)日:2014-04-29
申请号:US13782289
申请日:2013-03-01
申请人: Francis Law Group
发明人: Robert Matheny , Zachary Reinhardt
IPC分类号: A61F2/24
CPC分类号: A61F2/2412 , A61F2/2475 , A61F2250/006
摘要: A two-piece prosthetic valve having first and second members, a first end of the first member being sized and configured to receive a second end of the second member therein, the second end of the second member being attached to the first member at at least one commissure connection point to form at least one leaflet therein.
摘要翻译: 一种具有第一和第二构件的两件式人工瓣膜,所述第一构件的第一端的尺寸被设计成容纳所述第二构件的第二端,所述第二构件的所述第二端至少连接到所述第一构件 一个连接点,以形成至少一个传单。
-
公开(公告)号:US20130129834A1
公开(公告)日:2013-05-23
申请号:US13732754
申请日:2013-01-02
申请人: Francis Law Group
发明人: Robert G. Matheny
IPC分类号: A61L27/36
CPC分类号: A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号:US08784891B2
公开(公告)日:2014-07-22
申请号:US13732805
申请日:2013-01-02
申请人: Francis Law Group
发明人: Robert G Matheny
IPC分类号: A61K48/00 , A61L27/36 , A61L27/40 , A61K38/17 , A61K35/54 , A61L27/38 , A61K35/38 , A61K35/34 , A61K38/18 , A61K9/00
CPC分类号: A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号:US08778012B2
公开(公告)日:2014-07-15
申请号:US13686131
申请日:2012-11-27
申请人: Francis Law Group
发明人: Robert G. Matheny
CPC分类号: A61F2/06 , A61F2/848 , A61F2210/0004 , A61F2220/0016 , A61L27/3633 , A61L27/507 , A61L27/54 , A61L27/58
摘要: An extracellular matrix (ECM) construct having a biodegradable support scaffold that includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein, and at least a first layer of first ECM material disposed on the top surface of the support scaffold.
摘要翻译: 一种细胞外基质(ECM)构建体,其具有可生物降解的支撑支架,其包括能够刺穿组织并固定在其中的多个可生物降解的微针以及设置在支撑支架顶表面上的至少第一层第一ECM材料。
-
公开(公告)号:US20130129690A1
公开(公告)日:2013-05-23
申请号:US13732731
申请日:2013-01-02
申请人: Francis Law Group
发明人: Robert G. Matheny
IPC分类号: A61L27/38
CPC分类号: A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
公开(公告)号:US20140148897A1
公开(公告)日:2014-05-29
申请号:US13686131
申请日:2012-11-27
申请人: FRANCIS LAW GROUP
发明人: Robert G. Matheny
IPC分类号: A61F2/06
CPC分类号: A61F2/06 , A61F2/848 , A61F2210/0004 , A61F2220/0016 , A61L27/3633 , A61L27/507 , A61L27/54 , A61L27/58
摘要: An extracellular matrix (ECM) construct comprising a biodegradable support scaffold that includes a plurality of biodegradable microneedles that are capable of piercing tissue and anchoring therein, and at least a first layer of ECM material disposed on the top surface of the support scaffold. In some embodiments, the microneedles are capable of administering a pharmacological composition to the engaged tissue.
摘要翻译: 包含可生物降解支撑支架的细胞外基质(ECM)构建体,其包括能够刺穿组织并固定在其中的多个可生物降解的微针以及设置在支撑支架顶表面上的至少第一层ECM材料层。 在一些实施方案中,微针能够将药理组合物施用于接合组织。
-
公开(公告)号:US20140088339A1
公开(公告)日:2014-03-27
申请号:US13782115
申请日:2013-03-01
申请人: FRANCIS LAW GROUP
发明人: Robert Matheny
CPC分类号: A61K35/35 , A61K35/12 , A61K38/18 , A61K38/1808 , A61K38/1841 , A61K38/185 , A61K38/1866 , A61K45/06 , A61K48/00 , A61L27/3604 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3826 , A61L27/3834 , A61L27/54 , A61L2300/414 , A61L2300/434 , A61L2300/64 , A61L2430/20 , A61M1/122 , A61M2205/05
摘要: Methods for treating a cardiovascular disorder comprising concomitant administration of one or more extracellular matrix (ECM) based compositions directly to damaged or diseased cardiovascular tissue associated with the cardiovascular disorder, and provision of ventricular assistance. In a preferred embodiment, the ECM based compositions include an ECM material derived from a mammalian source.
摘要翻译: 用于治疗心血管疾病的方法包括将一种或多种基于细胞外基质(ECM)的组合物直接施用于与心血管疾病相关的受损或患病的心血管组织并提供心室辅助。 在优选的实施方案中,基于ECM的组合物包括衍生自哺乳动物来源的ECM材料。
-
公开(公告)号:US20130129831A1
公开(公告)日:2013-05-23
申请号:US13732805
申请日:2013-01-02
申请人: Francis Law Group
发明人: Robert G. Matheny
IPC分类号: A61L27/36
CPC分类号: A61L27/54 , A61K9/0019 , A61K31/7088 , A61K31/726 , A61K35/22 , A61K35/34 , A61K35/37 , A61K35/38 , A61K35/407 , A61K35/50 , A61K35/545 , A61K38/1741 , A61K38/1825 , A61K38/1841 , A61K38/39 , A61K48/00 , A61L27/227 , A61L27/3629 , A61L27/3633 , A61L27/367 , A61L27/3683 , A61L27/3687 , A61L27/3834 , A61L27/3873 , A61L27/40 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/426 , A61L2300/45 , A61L2300/64 , A61L2400/06 , A61L2430/20 , A61L2430/30
摘要: Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
-
-
-
-
-
-
-
-
-