公开(公告)号：US06541648B1

公开(公告)日：2003-04-01

申请号：US10088899

申请日：2002-06-26

Applicant: Giuseppe Paparatto ,  Anna Forlin ,  Giordano De Alberti ,  Rino D'Aloisio ,  Paolo Tegon

Inventor： Giuseppe Paparatto ,  Anna Forlin ,  Giordano De Alberti ,  Rino D'Aloisio ,  Paolo Tegon

IPC: C07D30112

CPC classification number: C07D301/12 ,  C01B15/029 ,  Y02P20/125

Abstract: The present invention relates to an integrated process for the preparation in continuous of epoxides which comprises: (a) preparing an alcoholic or hydro-alcoholic solution of hydrogen peroxide in a concentration of over 3% by weight, using a gaseous stream containing hydrogen, oxygen and an inert gas, in the presence of a bimetallic catalyst based on palladium and platinum as active components; (b) putting the alcoholic or hydro-alcoholic solution of hydrogen peroxide obtained in step (a) in contact with an olefin and a buffering agent, in the presence of an epoxidation catalyst suspended in the reaction solvent, in order to obtain a reaction mixture containing the epoxide corresponding to the olefin, water and the alcoholic solvent; (c) treating the alcoholic stream leaving step (b), after separation of the epoxide, in order to eliminate the nitrogenated compounds present; (d) feeding the alcoholic solvent obtained in (c) to step (a). A part of the solvent obtained in (c) can be used, when necessary, for diluting the hydro-alcoholic solution of hydrogen peroxide obtained in step (a) to the value required by the epoxidation plant. The process operates under high safety conditions and with a high overall efficiency, in terms of productivity and selectivity.

Abstract translation: 本发明涉及连续制备环氧化物的一体化方法，其包括：（a）使用含氢，氧气的气流制备浓度超过3重量％的过氧化氢的醇或醇 - 醇溶液 和在基于钯和铂作为活性组分的双金属催化剂存在下的惰性气体; （b）在悬浮在反应溶剂中的环氧化催化剂的存在下，将步骤（a）中得到的过氧化氢的醇或醇 - 醇溶液与烯烃和缓冲剂接触，以获得反应混合物 含有对应于烯烃，水和醇溶剂的环氧化物; （c）在分离环氧化物之后处理离开步骤（b）的醇流，以消除存在的含氮化合物; （d）将（c）中获得的醇溶剂进料到步骤（a）。 必要时可以使用（c）中得到的溶剂的一部分，将步骤（a）中得到的过氧化氢水溶液稀释至环氧化装置所要求的值。 该工艺在高安全性条件下运行，并且在生产率和选择性方面具有较高的总体效率。

公开(公告)号：US09498762B2

公开(公告)日：2016-11-22

申请号：US13983361

申请日：2012-02-03

Applicant: Philip J. Carlberg ,  Hannah L. Crampton ,  Anna Forlin ,  Esteban Pedernera ,  Cesar E. Meza

Inventor： Philip J. Carlberg ,  Hannah L. Crampton ,  Anna Forlin ,  Esteban Pedernera ,  Cesar E. Meza

IPC: B01J8/20 ,  B01J8/02 ,  C07D301/12 ,  C07D301/32 ,  B01D11/04 ,  B01J19/00

CPC classification number: B01J8/20 ,  B01D11/0488 ,  B01D11/0492 ,  B01J8/0278 ,  B01J19/00 ,  B01J2219/00247 ,  C07D301/12 ,  C07D301/32 ,  Y02P20/52

Abstract: Embodiments of the present disclosure are directed to a system and a process for producing an oxirane. For the various embodiments, the system and process of the present disclosure includes: a reaction vessel having a reaction mixture of an olefin, a peroxide compound, a solvent mixture with an alcohol and a non-reactive co-solvent, a solid phase, and reaction products of the reaction mixture, where the reaction products include an oxirane; a separation vessel coupled to the reaction vessel, where an effluent of the reaction mixture and reaction products from the reaction vessel separates in the separation vessel into a liquid aqueous phase and a liquid organic phase; and an extraction vessel coupled to an outlet of the separation vessel, where the liquid aqueous phase taken from the outlet of the separation vessel mixes with an extraction solvent to extract oxirane from the aqueous phase.

Abstract translation: 本公开的实施方案涉及用于生产环氧乙烷的系统和方法。 对于各种实施方案，本公开的系统和方法包括：反应容器，其具有烯烃，过氧化物化合物，溶剂混合物与醇和非反应性助溶剂的反应混合物，固相和 反应混合物的反应产物，其中反应产物包括环氧乙烷; 耦合到反应容器的分离容器，其中反应混合物的流出物和来自反应容器的反应产物在分离容器中分离成液体水相和液体有机相; 以及耦合到分离容器的出口的提取容器，其中从分离容器的出口取出的液体水相与提取溶剂混合以从水相中提取环氧乙烷。

公开(公告)号：US20130302216A1

公开(公告)日：2013-11-14

申请号：US13983361

申请日：2012-02-03

Applicant: Philip J. Carlberg ,  Hannah L. Crampton ,  Anna Forlin ,  Esteban Pedernera ,  Cesar E. Meza

Inventor： Philip J. Carlberg ,  Hannah L. Crampton ,  Anna Forlin ,  Esteban Pedernera ,  Cesar E. Meza

IPC: B01J19/00

CPC classification number: B01J8/20 ,  B01D11/0488 ,  B01D11/0492 ,  B01J8/0278 ,  B01J19/00 ,  B01J2219/00247 ,  C07D301/12 ,  C07D301/32 ,  Y02P20/52

Abstract: Embodiments of the present disclosure are directed to a system and a process for producing an oxirane. For the various embodiments, the system and process of the present disclosure includes: a reaction vessel having a reaction mixture of an olefin, a peroxide compound, a solvent mixture with an alcohol and a non-reactive co-solvent, a solid phase, and reaction products of the reaction mixture, where the reaction products include an oxirane; a separation vessel coupled to the reaction vessel, where an effluent of the reaction mixture and reaction products from the reaction vessel separates in the separation vessel into a liquid aqueous phase and a liquid organic phase; and an extraction vessel coupled to an outlet of the separation vessel, where the liquid aqueous phase taken from the outlet of the separation vessel mixes with an extraction solvent to extract oxirane from the aqueous phase.

Abstract translation: 本公开的实施方案涉及用于生产环氧乙烷的系统和方法。 对于各种实施方案，本公开的系统和方法包括：反应容器，其具有烯烃，过氧化物化合物，溶剂混合物与醇和非反应性助溶剂的反应混合物，固相和 反应混合物的反应产物，其中反应产物包括环氧乙烷; 耦合到反应容器的分离容器，其中反应混合物的流出物和来自反应容器的反应产物在分离容器中分离成液体水相和液体有机相; 以及耦合到分离容器的出口的提取容器，其中从分离容器的出口取出的液体水相与提取溶剂混合以从水相中提取环氧乙烷。

公开(公告)号：US20110152580A1

公开(公告)日：2011-06-23

申请号：US12595488

申请日：2008-04-11

Applicant: Bruce D. Hook ,  Anna Forlin ,  Andrei S. Merenov ,  Danil Tirtowidjolo ,  Anil J. Mehta ,  Jan W. Verwijs ,  Aaltje Verwijs-van den Brink ,  Lena Verwijs ,  Hendrika Gerrita Verwijs ,  Wilma Hensen

Inventor： Bruce D. Hook ,  Anna Forlin ,  Andrei S. Merenov ,  Danil Tirtowidjolo ,  Anil J. Mehta ,  Jan W. Verwijs ,  Aaltje Verwijs-van den Brink ,  Lena Verwijs ,  Hendrika Gerrita Verwijs ,  Wilma Hensen

IPC: C07C31/34 ,  B01J8/00

CPC classification number: B01D3/38 ,  B01D3/14 ,  B01D3/146 ,  B01D3/36 ,  C07C29/62 ,  Y02P20/127 ,  C07C31/42

Abstract: A process for converting multihydroxylated-aliphatic hydrocarbon compound(s) and/or ester(s) thereof to chlorohydrins and/or esters thereof is disclosed in which one or more of multihydroxylated-aliphatic hydrocarbon compound(s) and/or ester(s) thereof and/or monochlorohydrin(s) and/or ester(s) thereof with at least one chlorinating feed stream comprising at least one chlorinating agent and at least one impurity having a boiling point below the boiling point of the chlorohydrin product having the lowest boiling under hydrochlorination conditions, optionally in the presence of water, one or more catalyst(s), and/or one or more heavy byproduct(s) in a reaction vessel under hydrochlorination conditions, wherein the liquid-phase reaction mixture is maintained at a temperature below the boiling point of the chlorohydrin product having the lowest boiling point under hydrochlorination conditions and greater than the boiling point(s) of the at least one impurity and a vapor phase vent stream comprising the at least one impurity is removed from the liquid phase reaction mixture. An apparatus suitable for carrying out the disclosed process is illustrated in FIG. 1 of the drawings. The process and apparatus improve conversion rates and/or provide for recovery of chlorinating agent for lower operating costs.

Abstract translation: 公开了一种将多羟基化脂族烃化合物和/或其酯转化为氯醇和/或其酯的方法，其中一种或多种多羟基化脂族烃化合物和/或酯（一种或多种） 和/或一氯代醇和/或其酯与至少一种氯化进料流一起包含至少一种氯化剂和至少一种沸点低于具有最低沸点的氯代醇产物的沸点的杂质 在氢氯化条件下，任选地在氢氯化条件下在反应容器中存在水，一种或多种催化剂和/或一种或多种重质副产物，其中将液相反应混合物保持在温度 低于氢氯化条件下具有最低沸点的氯代醇产物的沸点并且大于至少一种杂质的沸点和气相排出流c 从液相反应混合物中除去至少一种杂质。 图1中示出了适用于执行所公开的处理的装置。 1图。 该方法和设备提高转化率和/或提供氯化剂的回收以降低运行成本。

公开(公告)号：US20100029848A1

公开(公告)日：2010-02-04

申请号：US12304924

申请日：2007-06-19

Applicant: Anna Forlin ,  Massimo Bergamo ,  Wells Carter ,  David Jean

Inventor： Anna Forlin ,  Massimo Bergamo ,  Wells Carter ,  David Jean

IPC: C08G65/22 ,  C07D301/03 ,  C08L63/00

CPC classification number: C07D301/12 ,  C07D303/38

Abstract: A process for producing an epoxide such as a cycloaliphatic diepoxide by the reaction of an olefin such as a cycloaliphatic diene with hydrogen peroxide (H2O2) as an oxidant in the presence of a catalytic system under pH control for example at a pH of less than about 5. The present invention is advantageously used for the epoxidation of olefinic compounds such as olefins and aliphatic or aromatic dienes.

Abstract translation: 在pH控制下，例如在小于约pH的pH控制下，在催化体系存在下，通过烯烃如脂环族二烯与过氧化氢（H 2 O 2）作为氧化剂的反应来制备环氧化物如环脂族二环氧化物的方法， 本发明有利地用于烯烃化合物如烯烃和脂族或芳族二烯烃的环氧化。

公开(公告)号：US20080306290A1

公开(公告)日：2008-12-11

申请号：US12159404

申请日：2006-12-18

Applicant: Hans-Georg Gobbel ,  Peter Bassler ,  Joaquim Henrique Teles ,  Peter Rudolf ,  Ulrich Muller ,  Anna Forlin ,  Malte Schulz ,  Meinolf Weidenbach

Inventor： Hans-Georg Gobbel ,  Peter Bassler ,  Joaquim Henrique Teles ,  Peter Rudolf ,  Ulrich Muller ,  Anna Forlin ,  Malte Schulz ,  Meinolf Weidenbach

IPC: C07D301/12

CPC classification number: C07D301/12

Abstract: The present invention provides a process for the epoxidation of propene which comprises reacting propene with hydrogen peroxide in the presence of methanol as solvent and a titanium zeolite catalyst, the process further comprising separating propylene oxide from the reaction mixture to obtain a mixture comprising methanol, water, at least one carboxylic acid and at least one carbonyl compound, wherein the at least one carboxylic acid is at least partially neutralized, said process optionally comprising a hydrogenation stage.

Abstract translation: 本发明提供丙烯环氧化方法，其包括在甲醇作为溶剂和钛沸石催化剂的存在下使丙烯与过氧化氢反应，该方法还包括从反应混合物中分离环氧丙烷以获得包含甲醇，水 ，至少一种羧酸和至少一种羰基化合物，其中所述至少一种羧酸被至少部分中和，所述方法任选地包含氢化阶段。

公开(公告)号：US08197645B2

公开(公告)日：2012-06-12

申请号：US12159321

申请日：2006-12-13

Applicant: Armin Diefenbacher ,  Hans-Georg Goebbel ,  Stefan Bitterlich ,  Hartwig Voss ,  Henning Schultz ,  Anna Forlin ,  Renate Patrascu

Inventor： Armin Diefenbacher ,  Hans-Georg Goebbel ,  Stefan Bitterlich ,  Hartwig Voss ,  Henning Schultz ,  Anna Forlin ,  Renate Patrascu

IPC: B01D1/26 ,  B01D3/14 ,  C07C29/80 ,  C07C31/18

CPC classification number: B01D1/26 ,  B01D1/02 ,  B01D3/148 ,  B01D3/322 ,  C07C29/80 ,  Y10S159/08 ,  Y10S203/17 ,  C07C31/205

Abstract: The present invention relates to a process for separating at least one propylene glycol from a mixture (M) comprising water and said propylene glycol, said process comprising (I) evaporating the mixture in at least two evaporation and/or distillation stages at decreasing operating pressures of the evaporators and/or distillation columns obtaining mixture (M′) and mixture (M″); (II) separating the mixture (M′) obtained in (I) in at least one further distillation step, obtaining a mixture (M-I) comprising at least 70 wt.-% of water and a mixture (M-II) comprising less than 30 wt.-% of water.

Abstract translation: 本发明涉及从包含水和所述丙二醇的混合物（M）中分离至少一种丙二醇的方法，所述方法包括（I）在降低的操作压力下在至少两个蒸发和/或蒸馏阶段蒸发混合物 的蒸发器和/或蒸馏塔获得混合物（M'）和混合物（M“）; （II）将在（I）中获得的混合物（M'）在至少一个另外的蒸馏步骤中分离，得到包含至少70重量％的水的混合物（MI）和包含少于 30重量％的水。

公开(公告)号：US07786317B2

公开(公告)日：2010-08-31

申请号：US12159404

申请日：2006-12-18

Applicant: Hans-Georg Goebbel ,  Peter Bassler ,  Joaquim Henrique Teles ,  Peter Rudolf ,  Ulrich Mueller ,  Anna Forlin ,  Malte Schulz ,  Meinolf Weidenbach

Inventor： Hans-Georg Goebbel ,  Peter Bassler ,  Joaquim Henrique Teles ,  Peter Rudolf ,  Ulrich Mueller ,  Anna Forlin ,  Malte Schulz ,  Meinolf Weidenbach

IPC: C07D301/12

CPC classification number: C07D301/12

Abstract: The present invention provides a process for the epoxidation of propene which comprises reacting propene with hydrogen peroxide in the presence of methanol as solvent and a titanium zeolite catalyst, the process further comprising separating propylene oxide from the reaction mixture to obtain a mixture comprising methanol, water, at least one carboxylic acid and at least one carbonyl compound, wherein the at least one carboxylic acid is at least partially neutralized, said process optionally comprising a hydrogenation stage.

Abstract translation: 本发明提供丙烯环氧化方法，其包括在甲醇作为溶剂和钛沸石催化剂的存在下使丙烯与过氧化氢反应，该方法还包括从反应混合物中分离环氧丙烷以获得包含甲醇，水 ，至少一种羧酸和至少一种羰基化合物，其中所述至少一种羧酸被至少部分中和，所述方法任选地包含氢化阶段。

公开(公告)号：US07138534B2

公开(公告)日：2006-11-21

申请号：US10344441

申请日：2001-08-13

Applicant: Anna Forlin ,  Paolo Tegon ,  Giuseppe Paparatto

Inventor： Anna Forlin ,  Paolo Tegon ,  Giuseppe Paparatto

IPC: C07D301/12

CPC classification number: C07D303/04 ,  C07D301/12

Abstract: A process for the continuous production of an olefinic oxide such as propylene oxide by direct catalytic oxidation of an olefin with hydrogen peroxide. The process involves successive reaction, distillation, decomposition, phase, separation, condensation and distillation with recycle of various streams to provide improved catalyst life and reaction selectivity.

Abstract translation: 通过用过氧化氢直接催化氧化烯烃来连续生产环氧丙烷等氧化烯的方法。 该方法包括连续反应，蒸馏，分解，相分离，缩合和蒸馏，各种流的再循环以提供改善的催化剂寿命和反应选择性。

公开(公告)号：US06300506B1

公开(公告)日：2001-10-09

申请号：US09626456

申请日：2000-07-26

Applicant: Giuseppe Paparatto ,  Anna Forlin ,  Paolo Tegon

Inventor： Giuseppe Paparatto ,  Anna Forlin ,  Paolo Tegon

IPC: C07D30112

CPC classification number: C07D301/12 ,  Y02P20/584

Abstract: A continuous process is described for the preparation of olefin oxides by direct epoxidation of an olefin with hydrogen peroxide, or compounds capable of producing hydrogen peroxide under the reaction conditions, in a solvent medium, in the presence of a catalytic system consisting of a zeolite containing titanium and a buffer system with a pH controlled within the values of 5.5 to 8.0, consisting of a nitrogenated base and a salt thereof with an organic or inorganic acid. The process allows high conversions and selectivities of the olefin into the corresponding oxide with a catalytic activity stable over a period of time.

Abstract translation: 描述了一种连续方法，用于通过在溶剂介质中，在由含有沸石的沸石组成的催化剂体系的存在下，用过氧化氢或能够在反应条件下能够产生过氧化氢的化合物直接环氧化烯烃氧化物 钛和缓冲体系，其pH值控制在5.5至8.0的范围内，由含氮碱和其与有机或无机酸的盐组成。 该方法允许烯烃的高转化率和选择性进入相应的氧化物，催化活性在一段时间内稳定。