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公开(公告)号：US08318059B2
公开(公告)日：2012-11-27
申请号：US12456409
申请日：2009-06-16
申请人： Brian Gerrard Devlin , Arturo Norberto Medina , Karen Belinda Sentell , Stephen Raymond Perreault , Mireille Tena
发明人： Brian Gerrard Devlin , Arturo Norberto Medina , Karen Belinda Sentell , Stephen Raymond Perreault , Mireille Tena
IPC分类号： B29C71/00
CPC分类号： C08L75/14 , A61L27/18 , C08G18/5024 , C08G18/6685 , C08G18/71 , C08G2120/00 , C08K3/32 , C08K5/092 , C08K5/098 , C08K5/175 , C08L71/02 , C08L2203/02 , C08L2666/04
摘要： The present invention provides a method for producing a medical device, preferably an ophthalmic device, more preferably a contact lens, made of a stabilized poly(oxyalkylene)-containing polymeric material. The method of the invention comprises the steps of: curing, in a mold, a composition comprising (a) a prepolymer having at least one poly(oxyalkylene) unit, (b) a biocompatible organic multi-acid or biocompatible salt thereof in an amount sufficient to improve the stability of the poly(oxyalkylene)-containing polymer made from the composition, (c) optionally a photoinitiator or a thermal initiator, and (d) optionally one or more vinylic monomers, to form the medical device being less susceptible to oxidative degradation; and removing the medical device from the mold.
摘要翻译： 本发明提供了一种用于制造医疗装置的方法，优选为由具有稳定的聚（氧化烯））聚合物材料制成的眼科装置，更优选隐形眼镜。 本发明的方法包括以下步骤：在模具中固化组合物，其包含（a）具有至少一个聚（氧化烯）单元的预聚物，（b）生物相容性有机多酸或其生物相容性盐的量 足以提高由组合物制备的聚（氧化烯）聚合物的稳定性，（c）任选的光引发剂或热引发剂，和（d）任选的一种或多种乙烯型单体，以形成不易受 氧化降解; 并从模具中取出医疗装置。
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公开(公告)号：US20120038880A1
公开(公告)日：2012-02-16
申请号：US13206205
申请日：2011-08-09
摘要： The present invention relates to a process for effectively curing a lens forming material to form a lens, preferably a contact lens. In particular the present invention relates to a modulated UV/VIS irradiation curing process, preferably using UV light, wherein the lens forming material is first cured with a very high intensity for a first short time period and then with a significantly lower intensity for a significantly longer time period.
摘要翻译： 本发明涉及一种有效固化透镜形成材料以形成透镜，优选隐形眼镜的方法。 特别地，本发明涉及优选使用UV光的调制的UV / VIS照射固化方法，其中首先在非常高的强度下首先固化透镜形成材料，然后以显着较低的强度固化， 更长的时间段
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13.发明申请PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION 有权基于光诱导步骤生长聚合的眼科装置的生产公开(公告)号：US20110269869A1
公开(公告)日：2011-11-03
申请号：US13182969
申请日：2011-07-14
CPC分类号： B29D11/00038 , C08F275/00 , G02B1/041 , G02B1/043 , C08L33/08 , C08L33/10 , C08L23/20
摘要： The invention provide a new lens curing method for making hydrogel contact lenses. The new lens curing method is based on actinically-induced step-growth polymerization. The invention also provides hydrogel contact lenses prepared from the method of the invention and fluid compositions for making hydrogel contact lenses based on the new lens curing method. In addition, the invention provide prepolymers capable of undergoing actinically-induced step-growth polymerization to form hydrogel contact lenses.
摘要翻译： 本发明提供一种制备水凝胶隐形眼镜的新型镜片固化方法。 新的透镜固化方法是基于光化诱导的步进增长聚合。 本发明还提供了根据本发明的方法制备的水凝胶隐形眼镜和基于新的镜片固化方法制备水凝胶隐形眼镜的流体组合物。 此外，本发明提供能够进行光化诱导的步进生长聚合以形成水凝胶隐形眼镜的预聚物。
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公开(公告)号：US20090263278A1
公开(公告)日：2009-10-22
申请号：US12456409
申请日：2009-06-16
申请人： Brian Gerrard Devlin , Arturo Norberto Medina , Karen Belinda Sentell , Stephen Raymond Perreault , Mireille Tena
发明人： Brian Gerrard Devlin , Arturo Norberto Medina , Karen Belinda Sentell , Stephen Raymond Perreault , Mireille Tena
IPC分类号： A61L2/18
CPC分类号： C08L75/14 , A61L27/18 , C08G18/5024 , C08G18/6685 , C08G18/71 , C08G2120/00 , C08K3/32 , C08K5/092 , C08K5/098 , C08K5/175 , C08L71/02 , C08L2203/02 , C08L2666/04
摘要： The present invention provides a method for producing a medical device, preferably an ophthalmic device, more preferably a contact lens, made of a stabilized poly(oxyalkylene)-containing polymeric material. The method of the invention comprises the steps of: curing, in a mold, a composition comprising (a) a prepolymer having at least one poly(oxyalkylene) unit, (b) a biocompatible organic multi-acid or biocompatible salt thereof in an amount sufficient to improve the stability of the poly(oxyalkylene)-containing polymer made from the composition, (c) optionally a photoinitiator or a thermal initiator, and (d) optionally one or more vinylic monomers, to form the medical device being less susceptible to oxidative degradation; and removing the medical device from the mold.
摘要翻译： 本发明提供了一种用于制造医疗装置的方法，优选为由具有稳定的聚（氧化烯））聚合物材料制成的眼科装置，更优选隐形眼镜。 本发明的方法包括以下步骤：在模具中固化组合物，其包含（a）具有至少一个聚（氧化烯）单元的预聚物，（b）生物相容性有机多酸或其生物相容性盐的量 足以提高由组合物制备的聚（氧化烯）聚合物的稳定性，（c）任选的光引发剂或热引发剂，和（d）任选的一种或多种乙烯型单体，以形成不易受 氧化降解; 并从模具中取出医疗装置。
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15.发明申请Production of ophthalmic devices based on photo-induced step growth polymerization 有权基于光诱导步骤生长聚合的眼科装置的生产公开(公告)号：US20080143958A1
公开(公告)日：2008-06-19
申请号：US12001562
申请日：2007-12-12
CPC分类号： B29D11/00038 , C08F275/00 , G02B1/041 , G02B1/043 , C08L33/08 , C08L33/10 , C08L23/20
摘要： The invention provide a new lens curing method for making hydrogel contact lenses. The new lens curing method is based on actinically-induced step-growth polymerization. The invention also provides hydrogel contact lenses prepared from the method of the invention and fluid compositions for making hydrogel contact lenses based on the new lens curing method. In addition, the invention provide prepolymers capable of undergoing actinically-induced step-growth polymerization to form hydrogel contact lenses.
摘要翻译： 本发明提供一种制备水凝胶隐形眼镜的新型镜片固化方法。 新的透镜固化方法是基于光化诱导的步进增长聚合。 本发明还提供了根据本发明的方法制备的水凝胶隐形眼镜和基于新的镜片固化方法制备水凝胶隐形眼镜的流体组合物。 此外，本发明提供能够进行光化诱导的步进生长聚合以形成水凝胶隐形眼镜的预聚物。
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