公开(公告)号：US20070225217A1

公开(公告)日：2007-09-27

申请号：US11594436

申请日：2006-11-08

Applicant: Todd Chappell ,  Benjamin Auspitz ,  Edward Jost-Price

Inventor： Todd Chappell ,  Benjamin Auspitz ,  Edward Jost-Price

IPC: A61K38/13 ,  A61K31/573 ,  A61K31/553 ,  A61K31/519 ,  A61K31/557

CPC classification number: A61K38/13 ,  A61K9/0014 ,  A61K9/0048 ,  A61K9/0051 ,  A61K31/222 ,  A61K31/4015 ,  A61K31/451 ,  A61K31/4545 ,  A61K31/4745 ,  A61K31/519 ,  A61K31/553 ,  A61K31/557 ,  A61K31/5575 ,  A61K31/573 ,  A61K45/06 ,  Y02A50/401 ,  A61K2300/00

Abstract: The invention features methods, compositions, and kits for treating an immunoinflammatory disorder, an ophthalmic disorder, a musculoskeletal disorder or pain associated therewith, a periodontal disease, or a disease or condition associated with an increased serum CRP level.

Abstract translation: 本发明的特征在于用于治疗免疫炎症，眼科疾病，肌肉骨骼疾病或与之相关的疼痛，牙周疾病或与血清CRP水平升高相关的疾病或病症的方法，组合物和试剂盒。

公开(公告)号：US20070110685A1

公开(公告)日：2007-05-17

申请号：US11454202

申请日：2006-06-16

Applicant: Benjamin Auspitz ,  Bradley Brasher ,  Todd Chappell ,  Michael Frank ,  Daniel Grau ,  Edward Jost-Price ,  Seth Lederman ,  Palaniyandi Manivasakam ,  Seth Orlow ,  Noah Sachs ,  Brendan Smith

Inventor： Benjamin Auspitz ,  Bradley Brasher ,  Todd Chappell ,  Michael Frank ,  Daniel Grau ,  Edward Jost-Price ,  Seth Lederman ,  Palaniyandi Manivasakam ,  Seth Orlow ,  Noah Sachs ,  Brendan Smith

IPC: A61K8/49 ,  A61K38/13 ,  A61K31/4745 ,  A61K31/385 ,  A61K31/522 ,  A61K31/4178

CPC classification number: A61K45/06 ,  A61K31/385 ,  A61K31/4178 ,  A61K31/4523 ,  A61K31/4745 ,  A61K31/522 ,  A61K38/13 ,  A61K2300/00

Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a non-steroidal immunophilin-dependent immunosuppressant (NsIDI) and a Group A enhancer (e.g., antifungal agent, antigout agent, anti-infective agent, antiprotozoal agent, antiviral agent, humectant, sunscreen, vitamin D compound, microtubuline inhibitor, or zinc salt) or analog or metabolite thereof to the patient. The invention also features a pharmaceutical composition containing an NsIDI and Group A enhancer or analog or metabolite thereof for the treatment or prevention of an immunoinflammatory disorder.

Abstract translation: 本发明的特征在于一种通过施用非甾体免疫亲和素依赖性免疫抑制剂（NsIDI）和A组增强剂（例如抗真菌剂，抗原性药物，抗炎药物）治疗诊断患有或有发展为免疫炎性疾病风险的患者的方法， 感染剂，抗原虫剂，抗病毒剂，保湿剂，防晒剂，维生素D化合物，微管免疫抑制剂或锌盐）或其类似物或代谢物。 本发明还特征在于含有NsIDI和A组增强剂或其类似物或代谢物的药物组合物，用于治疗或预防免疫炎性疾病。

公开(公告)号：US20050192261A1

公开(公告)日：2005-09-01

申请号：US10940902

申请日：2004-09-14

Applicant: Edward Jost-Price ,  Palaniyandi Manivasakam ,  Bradley Brasher ,  Brendan Smith ,  Noah Sachs ,  Benjamin Auspitz ,  Todd Chappell ,  Micheal Slavonic

Inventor： Edward Jost-Price ,  Palaniyandi Manivasakam ,  Bradley Brasher ,  Brendan Smith ,  Noah Sachs ,  Benjamin Auspitz ,  Todd Chappell ,  Micheal Slavonic

IPC: A61K31/00 ,  A61K31/4172 ,  A61K31/473 ,  A61K31/5415 ,  A61K31/573 ,  A61K38/13 ,  A61K45/06

CPC classification number: A61K45/06 ,  A61K31/00 ,  A61K31/4172 ,  A61K31/473 ,  A61K31/5415 ,  A61K31/573 ,  A61K38/13 ,  A61K2300/00

Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient an antihistamine, either alone or in combination with one or more additional agents. The invention also features a pharmaceutical composition containing an antihistamine in combination with one or more additional agents.

Abstract translation: 本发明的特征在于一种通过向患者施用单独或与一种或多种另外的试剂组合的抗组胺药来治疗诊断患有或有发展为免疫炎性疾病风险的患者的方法。 本发明还特征在于含有抗组胺剂与一种或多种另外的药剂组合的药物组合物。

公开(公告)号：US20050187200A1

公开(公告)日：2005-08-25

申请号：US10987554

申请日：2004-11-12

Applicant: Benjamin Auspitz ,  Alexis Borisy ,  Jason Fong ,  Nicole Hurst ,  Edward Jost-Price ,  Curtis Keith ,  Palaniyandi Manivasakam ,  Robyn Sackeyfio ,  Michael Slavonic ,  Brendan Smith ,  Grant Zimmermann

Inventor： Benjamin Auspitz ,  Alexis Borisy ,  Jason Fong ,  Nicole Hurst ,  Edward Jost-Price ,  Curtis Keith ,  Palaniyandi Manivasakam ,  Robyn Sackeyfio ,  Michael Slavonic ,  Brendan Smith ,  Grant Zimmermann

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/5415 ,  A61K31/551 ,  A61K31/565 ,  A61K31/573 ,  A61K31/59 ,  A61K31/60 ,  A61K38/13 ,  A61K45/06

CPC classification number: A61K45/06 ,  A61K31/565 ,  A61K38/13 ,  A61K2300/00

Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.

Abstract translation: 本发明的特征在于一种通过向患者施用三环化合物和任选的皮质类固醇或其它化合物来治疗被诊断患有免疫炎症疾病或有风险的患者的方法。 本发明还特征在于含有三环化合物和皮质类固醇或其它化合物的药物组合物，用于治疗或预防免疫炎性疾病。