Tissue implantable sensors for measurement of blood solutes
    11.
    发明申请
    Tissue implantable sensors for measurement of blood solutes 有权
    用于测量血液溶质的组织植入式传感器

    公开(公告)号:US20050059871A1

    公开(公告)日:2005-03-17

    申请号:US10698911

    申请日:2003-10-31

    IPC分类号: A61B5/00 A61B5/05

    摘要: A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes a multiplicity of detectors, constructed and arranged to improve the probability that one or more detectors will have access to a vascular source at points in time sufficient to permit accurate measurements to be taken. Means and methods for calculating solute levels using the sensor device of the invention are also provided.

    摘要翻译: 提供了用于测量流体和气体中的溶质(例如氧气和葡萄糖)的组织可植入传感器。 传感器包括多个检测器,其被构造和布置成提高一个或多个检测器在足以允许进行精确测量的时间点处进入血管源的概率。 还提供了使用本发明的传感器装置计算溶质水平的方法和方法。

    Operator independent image cytometer
    12.
    发明授权
    Operator independent image cytometer 失效
    操作者独立的图像细胞仪

    公开(公告)号:US5548661A

    公开(公告)日:1996-08-20

    申请号:US302044

    申请日:1994-09-07

    摘要: An operator independent image cytometer having a method for image segmentation. Image segmentation comprises the steps of filtering a digital image of a cellular specimen and thresholding the resultant image. In addition, the thresholding may include the sorting of features extracted from the filtered image. The present invention also includes a method for cytometer autofocus that combines the benefits of sharpening and contrast metrics. The present invention further includes an arc lamp stabilization and intensity control system. The image cytometer has broad applications in determining DNA content and other cellular measurements on as many as 10.sup.5 individual cells, including specimens of living cells. Image segmentation applications include PAP smear analysis and particle recognition.

    摘要翻译: 具有用于图像分割的方法的操作者独立的图像细胞计数器。 图像分割包括对细胞样本的数字图像进行过滤并对所得到的图像进行阈值化的步骤。 此外,阈值处理可以包括从滤波图像提取的特征的排序。 本发明还包括一种结合了锐化和对比度量度的优点的用于细胞仪自动对焦的方法。 本发明还包括弧光灯稳定和亮度控制系统。 图像细胞仪在确定多达105个个体细胞(包括活细胞标本)的DNA含量和其他细胞测量中具有广泛的应用。 图像分割应用包括PAP涂片分析和粒子识别。

    Portable Computer Having Multiple Embedded Audio Controllers
    15.
    发明申请
    Portable Computer Having Multiple Embedded Audio Controllers 审中-公开
    具有多个嵌入式音频控制器的便携式计算机

    公开(公告)号:US20120014533A1

    公开(公告)日:2012-01-19

    申请号:US13258842

    申请日:2010-01-29

    申请人: David Gough

    发明人: David Gough

    IPC分类号: H04R1/10 H04B1/00 G06F17/00

    CPC分类号: G06F3/165 H04H60/04

    摘要: Embodiments in accordance with the present invention provide two audio controllers embedded in a portable computer. According to one embodiment, a first audio controller 220 and a second audio controller 225 are coupled to a processing engine 230 and embedded. in a portable computer 200. The first audio controller and second audio controller are configured to be used simultaneously such that a user is capable of previewing a first audio stream output from either the first audio controller or second controller while a second audio stream is being output externally from the either the first audio controller or the second audio controller.

    摘要翻译: 根据本发明的实施例提供嵌入在便携式计算机中的两个音频控制器。 根据一个实施例,第一音频控制器220和第二音频控制器225耦合到处理引擎230并被嵌入。 在便携式计算机200中。第一音频控制器和第二音频控制器被配置为同时使用,使得用户能够预览来自第一音频控制器或第二控制器的第一音频流输出,同时输出第二音频流 从第一音频控制器或第二音频控制器的外部。

    Tissue implantable sensors for measurement of blood solutes
    16.
    发明申请
    Tissue implantable sensors for measurement of blood solutes 审中-公开
    用于测量血液溶质的组织植入式传感器

    公开(公告)号:US20080033272A1

    公开(公告)日:2008-02-07

    申请号:US11823477

    申请日:2007-06-26

    IPC分类号: A61B5/05

    摘要: A tissue-implantable sensor for measurement of solutes in fluids and gases, such as oxygen and glucose, is provided. The sensor includes a multiplicity of detectors, constructed and arranged to improve the probability that one or more detectors will have access to a vascular source at points in time sufficient to permit accurate measurements to be taken. Means and methods for calculating solute levels using the sensor device of the invention are also provided.

    摘要翻译: 提供了用于测量流体和气体中的溶质(例如氧气和葡萄糖)的组织可植入传感器。 传感器包括多个检测器,其被构造和布置成提高一个或多个检测器在足以允许进行精确测量的时间点处进入血管源的概率。 还提供了使用本发明的传感器装置计算溶质水平的方法和方法。

    Sensor probe for determining hydrogen peroxide concentration and method of use thereof
    17.
    发明授权
    Sensor probe for determining hydrogen peroxide concentration and method of use thereof 有权
    用于测定过氧化氢浓度的传感器探针及其使用方法

    公开(公告)号:US06592746B1

    公开(公告)日:2003-07-15

    申请号:US09673223

    申请日:2000-10-13

    IPC分类号: G01N27327

    CPC分类号: C12Q1/28 C12Q1/005

    摘要: A sensor probe is disclosed which can measure the hydrogen peroxide content of a single sample using two oxygen sensors whose electrodes are encased in defined membranes. The oxygen reference sensor is encased in a hydrophobic membrane which prevents the transport of hydrogen peroxide or electrochemical poisons or interferents and isolates the electrodes and an electrolyte fluid surrounding the electrodes from the sample fluid. The hydrogen-peroxide-generated oxygen (HPGO) sensor is also is encased in such a hydrophobic membrane, but has in series with and distally of the hydrophobic membrane a hydrophilic membrane which contains an immobilized enzyme such as catalase, peroxidase or other enzymes of a family which catalyzes the reaction of hydrogen peroxide to oxygen and water. At the HPGO sensor, the hydrogen peroxide is catalyzed to oxygen by the enzyme so that the HPGO sensor measures an enhanced concentration of oxygen relative to the oxygen reference sensor. The signals of each of the oxygen sensors are sent to a summer, which subtracts the equal background oxygen concentration of both, yielding a resultant difference signal representative of the concentration of hydrogen peroxide content of the sample itself. A suitable display or data collection device is used to capture the information in visible or digital form. Methods of use of the device for determining hydrogen peroxide content of human or animal tissues or fluids, or environmental or industrial fluids or fluid-containing materials, are also disclosed.

    摘要翻译: 公开了一种传感器探针,其可以使用两个氧传感器测量单个样品的过氧化氢含量,其中电极被封装在限定的膜中。 氧气参考传感器被封装在疏水膜中,其防止过氧化氢或电化学毒物或干扰物的输送并且将电极和电极周围的电解质流体与样品流体隔离。 过氧化氢生成的氧(HPGO)传感器也被包裹在这样的疏水膜中,但与疏水膜串联并且远离疏水膜的亲水膜,其含有固定化酶如过氧化氢酶,过氧化物酶或其它酶 催化过氧化氢与氧和水的反应的家庭。 在HPGO传感器中,过氧化氢通过酶催化为氧,使得HPGO传感器相对于氧参考传感器测量提高的氧浓度。 每个氧传感器的信号被送到夏天,其减去两者的相等的背景氧浓度,产生代表样品本身的过氧化氢含量浓度的得到的差异信号。 使用合适的显示或数据采集设备以可见或数字形式捕获信息。 还公开了用于测定人或动物组织或液体或环境或工业流体或含流体材料的过氧化氢含量的装置的使用方法。

    Arc lamp stabilization and intensity control for imaging microscopy
    18.
    发明授权
    Arc lamp stabilization and intensity control for imaging microscopy 失效
    电弧灯稳定和影像显微镜强度控制

    公开(公告)号:US5856665A

    公开(公告)日:1999-01-05

    申请号:US858293

    申请日:1997-05-19

    摘要: An operator independent image cytometer having a method for image segmentation. Image segmentation comprises the steps of filtering a digital image of a cellular specimen and thresholding the resultant image. In addition, the thresholding may include the sorting of features extracted from the filtered image. The present invention also includes a method for cytometer autofocus that combines the benefits of sharpening and contrast metrics. The present invention further includes an arc lamp stabilization and intensity control system. The image cytometer has broad applications in determining DNA content and other cellular measurements on as many as 10.sup.5 individual cells, including specimens of living cells. Image segmentation applications include PAP smear analysis and particle recognition.

    摘要翻译: 具有用于图像分割的方法的操作者独立的图像细胞计数器。 图像分割包括对细胞样本的数字图像进行过滤并对所得到的图像进行阈值化的步骤。 此外,阈值处理可以包括从滤波图像提取的特征的排序。 本发明还包括一种结合了锐化和对比度量度的优点的用于细胞仪自动对焦的方法。 本发明还包括弧光灯稳定和亮度控制系统。 图像细胞仪在确定多达105个个体细胞(包括活细胞标本)的DNA含量和其他细胞测量中具有广泛的应用。 图像分割应用包括PAP涂片分析和粒子识别。