公开(公告)号：US06942799B2

公开(公告)日：2005-09-13

申请号：US10380499

申请日：2001-09-14

Applicant: Diego Corcho-Sanchez ,  David Nicholas Lerner ,  Richard John Stephenson ,  Robert James Watkinson

Inventor： Diego Corcho-Sanchez ,  David Nicholas Lerner ,  Richard John Stephenson ,  Robert James Watkinson

IPC: C02F3/10 ,  C12M1/12 ,  C02F3/00

CPC classification number: C12M29/04

Abstract: A bioreactor for microbial conversion of at least one conversion substrate, which has a treatment zone to accommodate when in use a solution of at least one conversion substrate, a culture holding zone to accommodate when in use a microbial culture capable of metabolizing at least one conversion substrate, a source of primary growth substrate for the microbial culture, a first permeable membrane forming an interface between the treatment zone and the culture holding zone, and a second permeable membrane forming an interface between the source of primary growth substrate and the culture holding zone, the first permeable membrane being of a material which will allow passage of the at least one conversion substrate from the treatment zone to the culture holding zone whilst being impermeable to the microbial culture, the second permeable membrane being of a material permeable to the primary growth substrate but substantially impermeable to water; and a process of operating said bioreactor.

Abstract translation: 一种用于至少一种转化底物的微生物转化的生物反应器，其具有治疗区，以在使用时适应至少一种转化底物的溶液，培养保持区，以在使用时适应能够代谢至少一种转化的微生物培养物 底物，用于微生物培养的初级生长底物的源，形成处理区和培养保持区之间的界面的第一渗透膜，以及形成初级生长底物源和培养保持区之间的界面的第二渗透膜 所述第一渗透膜是允许所述至少一个转化底物从所述处理区通过所述培养保持区同时对所述微生物培养不可渗透的材料，所述第二渗透膜是可渗透所述初级生长的材料 基材，但基本上不可透过水; 以及操作所述生物反应器的过程。

公开(公告)号：US20050187576A1

公开(公告)日：2005-08-25

申请号：US10785672

申请日：2004-02-23

Applicant: Michael Whitman ,  David Nicholas

Inventor： Michael Whitman ,  David Nicholas

IPC: A61B17/04 ,  A61B17/115 ,  A61B17/32

CPC classification number: A61B17/068 ,  A61B17/115 ,  A61B17/1155 ,  A61B17/32053 ,  A61B2017/07285 ,  A61B2017/320052

Abstract: The present invention, in accordance with various embodiments thereof, relates to a surgical device for at least one of cutting and stapling a section of tissue. The surgical device includes a housing including at least two drivers. The surgical device also includes an anvil mechanically attachable to the housing and moveable relative to the housing between an open position and a closed position. The first driver operates to move the anvil relative to the housing to an intermediate position between the open position and the closed position. The second driver operates to move at least a portion of the housing relative to the anvil between the intermediate position and the closed position.

Abstract translation: 根据本发明的各种实施例，本发明涉及用于切割和缝合组织部分中的至少一个的外科装置。 手术装置包括包括至少两个驱动器的壳体。 手术装置还包括机械地附接到壳体并且可相对于壳体在打开位置和关闭位置之间移动的砧座。 第一驱动器操作以将砧座相对于壳体移动到打开位置和关闭位置之间的中间位置。 第二驱动器操作以相对于砧座在中间位置和关闭位置之间移动壳体的至少一部分。

公开(公告)号：US06226791B1

公开(公告)日：2001-05-01

申请号：US09049302

申请日：1998-03-27

Applicant: William Augustus Carter ,  Alan Roeder Elderon ,  Timothy David Magee ,  Mark David Nicholas ,  Henry Y. Saade ,  Grant Sutherland ,  William Nicholas John Tindall ,  Jeffrey Ramesh Urs ,  Timothy Edward Weinmann ,  Michael Thomas Wheatley

Inventor： William Augustus Carter ,  Alan Roeder Elderon ,  Timothy David Magee ,  Mark David Nicholas ,  Henry Y. Saade ,  Grant Sutherland ,  William Nicholas John Tindall ,  Jeffrey Ramesh Urs ,  Timothy Edward Weinmann ,  Michael Thomas Wheatley

IPC: G06F945

CPC classification number: G06F8/78

Abstract: A method, apparatus, and article for solving the year 2000 problem involves limited modifications in the data definition portions of the source code and compiler support for processing the modified source code. Fields in the source code that contain a year or date values are identified and, for each such field, the user selects an appropriate technique (for example, expansion, compression or windowing). The user modifies the data definition for each identified field, by adding new attributes to request the selected technique. The user then compiles the program and resolves any ambiguous references to the variables whose definitions were modified. This procedure is applied, module by module, and each processed module is merged into production, after testing, by using a compiler option to disable the use of the new attributes. A compiler option provides for the generation of debugger hooks for each statement that has been affected by modified declarations, which may be used with a suitably equipped debugger or other run-time analysis tool.

Abstract translation: 解决2000年问题的方法，装置和文章涉及对源代码的数据定义部分进行有限的修改和用于处理修改的源代码的编译器支持。 识别源代码中包含年或日期值的字段，并且对于每个这样的字段，用户选择适当的技术（例如，扩展，压缩或窗口化）。 用户通过添加新属性来请求所选择的技术来修改每个标识字段的数据定义。 用户然后编译程序并解析对定义被修改的变量的任何模糊引用。 该过程逐个应用，并且每个处理后的模块被合并到生产中，经过测试，通过使用编译器选项来禁用新属性的使用。 一个编译器选项为每个已经被修改的声明影响的语句生成调试器钩子，这可以与适当装配的调试器或其他运行时分析工具一起使用。

公开(公告)号：US4084351A

公开(公告)日：1978-04-18

申请号：US778843

申请日：1977-03-18

Applicant: David Nicholas Lam ,  Stephen Joseph Lam

Inventor： David Nicholas Lam ,  Stephen Joseph Lam

IPC: B24B41/00 ,  B24B41/06 ,  B24B7/22 ,  B28D5/00

CPC classification number: B24B41/00

Abstract: A diamond polishing workbench having a top working surface substantially free of vibration comprises an open rectangular steel frame having a peripheral shoulder on its interior. A first support table is rested within the shoulder and is mechanically insulated from the frame by a vibration damping material and a polishing wheel mount is connected to the first table. A second table is seated on the upper surface of the frame and is also mechanically insulated from the frame by a suitable vibration damping material.

Abstract translation: 具有基本上没有振动的顶部工作表面的金刚石抛光工作台包括在其内部具有周边肩部的开放的矩形钢框架。 第一支撑台搁置在肩部内，并通过减振材料与框架机械绝缘，并且抛光轮安装件连接到第一台。 第二个工作台位于框架的上表面上，并通过合适的减震材料与框架机械绝缘。

公开(公告)号：US11460200B2

公开(公告)日：2022-10-04

申请号：US16106428

申请日：2018-08-21

Applicant: Kenneth Horvath ,  David Nicholas Hodge

Inventor： Kenneth Horvath ,  David Nicholas Hodge

IPC: F24F7/007 ,  F24F11/00 ,  F24F13/28

Abstract: An air circulation and/or purification device for recirculating air and/or removing contaminants from the air which includes a housing having a top with an opening for air intake and a bottom, a fan contained within the housing, and a plurality of air output vents contained within multiple sides of the housing near the bottom of the housing. The bottom of the housing may include a conical shaped portion extending inward from the bottom of the housing or other structures to assist in expelling air from the housing in at least two different directions. The device may also include one or more filters designed to capture and filter out different types of contaminants.

公开(公告)号：US08517241B2

公开(公告)日：2013-08-27

申请号：US13039677

申请日：2011-03-03

Applicant: David Nicholas ,  Donald Malinouskas ,  David Zeichner

Inventor： David Nicholas ,  Donald Malinouskas ,  David Zeichner

IPC: A61B17/068

CPC classification number: A61B17/00234 ,  A61B17/068 ,  A61B17/07207 ,  A61B34/70 ,  A61B2017/00398 ,  A61B2017/00473 ,  A61B2090/0814

Abstract: A surgical system is provided and includes an intelligent surgical device having a drive motor supported in the housing and being in electrical communication with the power source; and control circuitry. The control circuitry includes a feedback system for monitoring a condition of the surgical device during a use thereof and for changing an operative parameter of the surgical device when a change in the monitored condition occurs. The surgical system includes a non-intelligent loading unit for selective connection to the housing of the surgical device and which is actuatable by the drive motor, the loading unit having a first and a second condition. During operation, the drive motor actuates the loading unit from the first condition to the second condition; and when the loading unit achieves the second condition, a change in the at least one monitored condition occurs and an operative parameter of the surgical device is changed.

Abstract translation: 提供了一种手术系统，并且包括具有支撑在壳体中并与电源电连通的驱动马达的智能手术装置; 和控制电路。 控制电路包括用于在使用期间监测外科手术装置的状况的反馈系统，以及当所监视的状况发生变化时改变手术装置的操作参数。 手术系统包括非智能加载单元，用于选择性地连接到手术装置的壳体并且可由驱动马达驱动，装载单元具有第一和第二状态。 在运行过程中，驱动电机使加载单元从第一状态起动至第二状态; 并且当加载单元达到第二条件时，发生至少一个监视条件的变化，并且改变外科装置的手术参数。

公开(公告)号：US20110198385A1

公开(公告)日：2011-08-18

申请号：US13089672

申请日：2011-04-19

Applicant: Michael P. Whitman ,  Donald Malinouskas ,  Peter Datcuk ,  David Nicholas

Inventor： Michael P. Whitman ,  Donald Malinouskas ,  Peter Datcuk ,  David Nicholas

IPC: A61B17/068

CPC classification number: A61B17/068 ,  A61B17/072 ,  A61B17/07207 ,  A61B90/98 ,  A61B2017/00398 ,  A61B2017/00464 ,  A61B2017/00734 ,  A61B2017/07214 ,  A61B2017/2923 ,  A61B2017/2926 ,  A61B2017/2943 ,  G06F19/00

Abstract: A surgical device is provided, the surgical device including a first driver for performing a first movement function; a second driver for performing a second movement function; a first rotatable drive shaft configured, upon actuation, to cause selective engagement of one of the first and second drivers with a second rotatable drive shaft, wherein the second rotatable drive shaft is configured to drive the selectively engaged one of the first and second drivers. Third and fourth drivers may also be included. The drivers may function to rotate a shaft portion of the surgical device relative to, and about the longitudinal axis of, a handle; move a jaw portion relative to the shaft portion; move a first jaw relative to a second jaw; and/or move a surgical member within the second jaw.

公开(公告)号：US20110192883A1

公开(公告)日：2011-08-11

申请号：US13089473

申请日：2011-04-19

Applicant: Michael P. Whitman ,  Donald Malinouskas ,  Peter Datcuk ,  David Nicholas

Inventor： Michael P. Whitman ,  Donald Malinouskas ,  Peter Datcuk ,  David Nicholas

IPC: A61B17/068

CPC classification number: A61B17/068 ,  A61B17/072 ,  A61B17/07207 ,  A61B90/98 ,  A61B2017/00398 ,  A61B2017/00464 ,  A61B2017/00734 ,  A61B2017/07214 ,  A61B2017/2923 ,  A61B2017/2926 ,  A61B2017/2943 ,  G06F19/00

Abstract: A surgical device is provided, the surgical device including a first driver for performing a first movement function; a second driver for performing a second movement function; a first rotatable drive shaft configured, upon actuation, to cause selective engagement of one of the first and second drivers with a second rotatable drive shaft, wherein the second rotatable drive shaft is configured to drive the selectively engaged one of the first and second drivers. Third and fourth drivers may also be included. The drivers may function to rotate a shaft portion of the surgical device relative to, and about the longitudinal axis of, a handle; move a jaw portion relative to the shaft portion; move a first jaw relative to a second jaw; and/or move a surgical member within the second jaw.

Abstract translation: 提供外科装置，所述手术装置包括用于执行第一移动功能的第一驱动器; 用于执行第二移动功能的第二驱动器; 第一可旋转驱动轴构造成在致动时使第一和第二驱动器之一与第二可旋转驱动轴选择性地接合，其中第二可旋转驱动轴构造成驱动第一和第二驱动器中选择性接合的一个。 也可以包括第三和第四驱动程序。 驱动器可以用于相对于手柄的纵轴线并且围绕手柄的纵向轴线旋转手术装置的轴部分; 相对于轴部分移动钳口部分; 相对于第二颚移动第一颚; 和/或在第二钳口内移动手术构件。

公开(公告)号：US20090101692A1

公开(公告)日：2009-04-23

申请号：US12235362

申请日：2008-09-22

Applicant: Michael P. Whitman ,  Donald Malinouskas ,  Peter Datcuk ,  David Nicholas

Inventor： Michael P. Whitman ,  Donald Malinouskas ,  Peter Datcuk ,  David Nicholas

IPC: A61B17/068

CPC classification number: A61B17/068 ,  A61B17/072 ,  A61B17/07207 ,  A61B90/98 ,  A61B2017/00398 ,  A61B2017/00464 ,  A61B2017/00734 ,  A61B2017/07214 ,  A61B2017/2923 ,  A61B2017/2926 ,  A61B2017/2943 ,  G06F19/00

Abstract: A surgical device is provided, the surgical device including a first driver for performing a first movement function; a second driver for performing a second movement function; a first rotatable drive shaft configured, upon actuation, to cause selective engagement of one of the first and second drivers with a second rotatable drive shaft, wherein the second rotatable drive shaft is configured to drive the selectively engaged one of the first and second drivers. Third and fourth drivers may also be included. The drivers may function to rotate a shaft portion of the surgical device relative to, and about the longitudinal axis of, a handle; move a jaw portion relative to the shaft portion; move a first jaw relative to a second jaw; and/or move a surgical member within the second jaw.

Abstract translation: 提供外科装置，所述手术装置包括用于执行第一移动功能的第一驱动器; 用于执行第二移动功能的第二驱动器; 第一可旋转驱动轴构造成在致动时使第一和第二驱动器之一与第二可旋转驱动轴选择性地接合，其中第二可旋转驱动轴构造成驱动第一和第二驱动器中选择性接合的一个。 也可以包括第三和第四驱动程序。 驱动器可以用于相对于手柄的纵轴线并且围绕手柄的纵向轴线旋转手术装置的轴部分; 相对于轴部分移动钳口部分; 相对于第二颚移动第一颚; 和/或在第二钳口内移动手术构件。

公开(公告)号：US20090039088A1

公开(公告)日：2009-02-12

申请号：US12115530

申请日：2008-05-05

Applicant: Preston Noel Williams ,  Henry Adolph Cousineau, III ,  Arnold Charles Hillman ,  Christian Peter Kramer ,  David Nicholas Legas

Inventor： Preston Noel Williams ,  Henry Adolph Cousineau, III ,  Arnold Charles Hillman ,  Christian Peter Kramer ,  David Nicholas Legas

IPC: B65D81/38

CPC classification number: F25D3/08 ,  F25D2303/082 ,  F25D2303/0844 ,  F25D2303/0845 ,  F25D2331/804

Abstract: The present invention is directed to a transport package which efficiently maintains payload temperature within a predetermined temperature range during delivery through regions having ambient temperatures outside the desired range. The transport package is used for transporting temperature sensitive materials and thermally protecting the materials from cold and hot ambient temperatures in a manner that does not require a power source or other mechanical devices. Aspects of the invention relate to a temperature maintaining packaging system having an outer container, thermal insulation materials and two or more different phase change materials.

Abstract translation: 本发明涉及一种运输包装，其在通过具有超出所需范围的环境温度的区域的输送期间将有效载荷温度有效地维持在预定温度范围内。 运输包装用于运输温度敏感材料，并以不需要电源或其他机械装置的方式将材料热保护于冷和热环境温度。 本发明的方面涉及具有外部容器，绝热材料和两种或更多种不同相变材料的温度保持包装系统。