公开(公告)号：US20090046756A1

公开(公告)日：2009-02-19

申请号：US11795653

申请日：2005-06-03

Applicant: Xianhua Wang ,  Guoliang Huang ,  Jing Cheng ,  Hong Zhang ,  Taishan Gao

Inventor： Xianhua Wang ,  Guoliang Huang ,  Jing Cheng ,  Hong Zhang ,  Taishan Gao

IPC: H01S3/08 ,  H01S3/10

CPC classification number: G02B21/002 ,  G01N21/6452

Abstract: The invention provides a novel optical system for use in a microarray scanner, comprising an aperture-containing reflecting mirror comprising an aperture and a reflecting surface. The aperture of the aperture-containing reflecting mirror allows an excitation light to pass through, and the reflecting surface of the aperture-containing reflecting mirror allows emission light from a microarray to be reflected. The optical system may also comprises various other components such as laser generators, beam splitter, reflecting mirrors, excitation and emission light filters, excitation and emission objective lens, pinhole, and detector. The optical system described herein has high efficiency, high sensitivity, low background noise, structurally simple, and high versatility.

Abstract translation: 本发明提供了一种用于微阵列扫描仪的新型光学系统，其包括一个包含孔和反射表面的孔径反射镜。 含孔反射镜的孔径允许激发光通过，并且含孔反射镜的反射表面允许来自微阵列的发射光被反射。 光学系统还可以包括诸如激光发生器，分束器，反射镜，激发和发射滤光器，激发和发射物镜，针孔和检测器的各种其它部件。 本文描述的光学系统具有高效率，高灵敏度，低背景噪声，结构简单和高通用性。

公开(公告)号：US20080252954A1

公开(公告)日：2008-10-16

申请号：US11795660

申请日：2005-06-02

Applicant: Xianhua Wang ,  Hui Xu ,  Jianxin Ye ,  Yelei Sun ,  Guoliang Huang ,  Jing Cheng

Inventor： Xianhua Wang ,  Hui Xu ,  Jianxin Ye ,  Yelei Sun ,  Guoliang Huang ,  Jing Cheng

IPC: G02B26/08

CPC classification number: G01N21/6458 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6421 ,  G01N2201/10 ,  G01N2201/103

Abstract: The invention provides a laser microarray scanner for microarray scanning, comprising an optical system, a scanning platform, and a data processing system. During scanning, the optical system remains fixed, and the microarray placed on the scanning platform moves relative to the optical system. The microarray scanner disclosed herein has high scanning speed, high sensitivity, high resolution, and high signal-to-noise ratio, thus is ideal for use in microarray scanning

Abstract translation: 本发明提供一种用于微阵列扫描的激光微阵列扫描器，包括光学系统，扫描平台和数据处理系统。 在扫描期间，光学系统保持固定，并且放置在扫描平台上的微阵列相对于光学系统移动。 本文公开的微阵列扫描器具有高扫描速度，高灵敏度，高分辨率和高信噪比，因此是理想的用于微阵列扫描