公开(公告)号：US20220326228A1

公开(公告)日：2022-10-13

申请号：US17625351

申请日：2020-07-09

Applicant: UNIVERSITÉ DE BORDEAUX ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： MARIE-CHRISTINE DURRIEU ,  SYLVAIN NLATE ,  CHRISTEL CHANSEAU ,  JIAN-QIAO JIANG

IPC: G01N33/53 ,  G01N33/533 ,  C07F3/06

Abstract: The invention relates to ligands able to bind to microvesicles, comprising a plurality of metal(II)-dipicolylamine moieties and their use in the diagnosis or prognostic of disorders in a subject.

公开(公告)号：US20220325043A1

公开(公告)日：2022-10-13

申请号：US17640020

申请日：2020-09-03

Applicant: UNIVERSITÉ DE BORDEAUX ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  Centre national de la recherche scientifique

Inventor： Sébastien LECOMMANDOUX ,  Colin BONDUELLE ,  Elisabeth GARANGER ,  Chloé GRAZON

IPC: C08G69/10

Abstract: The present invention relates to a “one-pot” method for preparing an aqueous solution of nanoparticles with amphiphilic block copolymers and comprising polypeptide units, the method comprising at least one step (E1), in an aqueous solvent, consisting of bringing together: —at least one hydrophilic polymer (P1) comprising at least one amine function, and —at least one hydrophobic α-amino acid N-carboxyanhydride monomer.

公开(公告)号：US20220289873A1

公开(公告)日：2022-09-15

申请号：US17626311

申请日：2020-07-09

Applicant: BOSTIK SA ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE DE BORDEAUX ,  INSTITUT POLYTECHNIQUE DE BORDEAUX

Inventor： Guillaume MICHAUD ,  Frédéric SIMON ,  Stéphane FOUQUAY ,  Boris COLIN ,  Virginie LIAUTARD ,  Mathieu PUCHEAULT

IPC: C08F4/12 ,  C08F120/14 ,  C09J7/10

Abstract: The invention relates to a process for polymerizing at least one radically polymerizable compound having at least one ethylenic bond in the presence of a borane complex BH3 with an amine as a radical initiator, said process comprising the steps of: providing a borane complex BH3 with an amine; and bringing the complex into contact with a composition comprising at least one radically polymerizable compound having at least one ethylenic bond; wherein the polymerization is performed in the absence of an oxidizing agent and/or an additional radical initiator other than the borane complex BH3 with an amine. The invention also relates to a composition comprising at least one radically polymerizable compound having at least one ethylenic bond and a borane complex BH3 with an amine, wherein the composition is free of an oxidizing agent and/or an additional radical initiator other than the borane complex BH3 with an amine, as well as the use of said composition as an adhesive for bonding two substrates together.

公开(公告)号：US20220098343A1

公开(公告)日：2022-03-31

申请号：US17414444

申请日：2019-12-16

Applicant: Arkema France ,  UNIVERSITE DE BORDEAUX ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Georges HADZIIOANNOU ,  Eric CLOUTET ,  Cyril BROCHON ,  Konstantinos KALLITSIS ,  Fabrice DOMINGUES DOS SANTOS ,  Thibaut SOULESTIN

IPC: C08F214/22 ,  C08F8/06 ,  C08J5/18 ,  C08L27/16

Abstract: A copolymer including units derived from fluoro monomers of formula (I): CX1X2═CX3X4  (I) in which each of the X1, X2, X3 and X4 is independently chosen from H, F and alkyl groups including from 1 to 3 carbon atoms which are optionally partially or totally fluorinated, the H and/or F atoms of the fluoro monomers being partially replaced with photoactive groups of formula —Y—Ar—R in the copolymer; Y representing an oxygen atom or an NH group or a sulfur atom, Ar representing an aryl group, preferably a phenyl group, and R being a monodentate or bidentate group including from 1 to 30 carbon atoms. The fluoro monomers of formula (I) of the copolymer include vinylidene fluoride and trifluoroethylene. Also, a process for preparing this copolymer, a composition including this copolymer, and a film obtained from the copolymer.

公开(公告)号：US20210151846A1

公开(公告)日：2021-05-20

申请号：US16768917

申请日：2018-12-05

Applicant: UNIVERSITÉ DE BORDEAUX ,  CENTRE NATIONAL D'ETUDES SPATIALES ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Anthony GHIOTTO ,  Frédéric PARMENT

IPC: H01P3/12 ,  H01P11/00

Abstract: This microwave component (10) comprises a waveguide (12) comprising an upper layer, a lower layer, and a central layer (18) intermediate between the upper layer and the lower layer, said layers defining a zone (19) of propagation of an electromagnetic wave, the propagation zone (19) extending along a propagation axis, and comprising a cavity (32) bounded by the upper layer, the lower layer, and, laterally, by two opposite lateral edges (36) of the central layer (18).
The waveguide (12) comprises at least one dielectric strip (28) placed in the propagation zone (19), the dielectric strip (28) being defined in one of the upper layer and the lower layer or being placed in the cavity (32) away from the lateral edges (36) of the cavity (32).

公开(公告)号：US20210128041A1

公开(公告)日：2021-05-06

申请号：US16472029

申请日：2017-12-20

Applicant: UNIVERSITE DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  ECOLE NATIONALE SUPERIEURE DES ARTS ET METIERS

Inventor： Jocelyn SABATIER ,  Frédéric BOS ,  Adrien CAPORALE ,  Ludovic DELHOMME ,  Anne THÉVENOUX ,  Fanny MUNSCH

IPC: A61B5/22 ,  A61B5/055 ,  A63B21/008 ,  A63B21/00 ,  A63B22/06 ,  A63B24/00

Abstract: The present invention concerns an ergometer (10) comprising at least one training assembly, each assembly comprising: a training element (11), -at least one hydraulic cylinder (12) comprising a pressure chamber (32), said training element (11) being linked to said at least one hydraulic cylinder (12) such that a hydraulic pressure value applied in the pressure chamber (32) of said or at least one of said corresponding cylinders determines a force opposing the movement of said training element (11) by a user, and at least one control unit (13, 14) for supplying the pressure chamber (32) of said or one corresponding hydraulic cylinder (12) with pressurised hydraulic fluid such that said pressure chamber (32) has a chosen pressure value during at least a part of the muscle exercises carried out by the user, said control unit (13, 14) being linked to said pressure chamber (32) of the corresponding hydraulic cylinder (12) by a hydraulic fluid supply circuit.

公开(公告)号：US10978037B2

公开(公告)日：2021-04-13

申请号：US15567066

申请日：2016-04-29

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  UNIVERSITE DE BORDEAUX

Inventor： Olivier Mondain-Monval ,  Thomas Brunet ,  Aurore Merlin ,  Kévin Zimmy ,  Artem Kovalenko ,  Benoît Mascaro

IPC: G10K11/172 ,  G10K11/162 ,  G10K11/165 ,  B01J2/06

Abstract: A porous acoustic bead resonator is provided, wherein the Young's modulus of the material of the resonator is lower than 1 GPa and the porosity of the resonator is comprised between 20% and 50%, most of the pores of the resonator being filled with a gas and most of the pores being interconnected, via at least one pore, with the exterior of the resonator.

公开(公告)号：US20200377116A1

公开(公告)日：2020-12-03

申请号：US16492550

申请日：2018-03-12

Applicant: PSA AUTOMOBILES SA ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  UNIVERSITE DE BORDEAUX

Inventor： Sergey ABRASHOV ,  Francois AIOUN ,  Franck GUILLEMARD ,  Rachid MALTI ,  Xavier MOREAU

IPC: B60W60/00 ,  B60W30/10 ,  B60W40/08 ,  B62D1/06 ,  B60W50/14 ,  B60J1/02 ,  B62D1/16 ,  B62D5/04

Abstract: A method is intended to assist the driver of a vehicle (VA) capable of being driven in an automated manner and in a manual manner, by means of a steering wheel (VV), in a traffic lane (VC1). This method comprises a step that involves determining an optimum trajectory of the vehicle (VA) in the event of automated driving, an actual current trajectory of the vehicle (VA) in the traffic lane (VC1), and a value of a parameter representative of a manual intervention being carried out by the driver on the steering wheel (VV), and representing these determined optimum and actual current trajectories on a medium (EA) with an aspect that depends on this determined value of the parameter.

公开(公告)号：US20200333536A1

公开(公告)日：2020-10-22

申请号：US16769532

申请日：2018-12-10

Applicant: Université de Bordeaux ,  Institut Polytechnique de Bordeaux ,  Centre National de la Recherche Scientifique ,  Université de technologie de Compiègne

Inventor： Karsten HAUPT ,  Cédric AYELA ,  Frank BOKELOH

IPC: G02B6/36 ,  G01D5/353

Abstract: The present invention relates to a sensor device comprising an optical fiber to be coupled with a laser beam, a through-fiber fabricated cantilever onto one end of said optical fiber, and a light collector. According to the invention, the through-fiber fabricated cantilever is made of a polymer obtained by photo-structuring at least one photo-sensitive monomer species. The present invention also relates to methods for the measurement of parameters such as temperature, mass, viscosity, analyte concentrations, and the degree of a polymerization process, using the device of the invention.

公开(公告)号：US20200165665A1

公开(公告)日：2020-05-28

申请号：US16630521

申请日：2018-07-12

Applicant: UNIVERSITE DE BORDEAUX ,  CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX ,  INSTITUT POLYTECHNIQUE DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： THIERRY SCHAEVERBEKE ,  THOMAS BAZIN ,  KATARZYNA HOOKS ,  MACHA NIKOLSKI

IPC: C12Q1/689 ,  C12Q1/686

Abstract: The present invention relates to an ex vivo method for predicting anti-TNF alpha response in a patient with an inflammatory disease in which this treatment is generally indicated, comprising the steps of: a) Measuring, before any anti-TNF alpha treatment, the level LM of Burkholderiales in a patient stool sample, and b) Calculating the score S1=LM/Lref, Wherein: ⋅If S1>1, the patient is considered likely to have a clinical response to an anti-TNF alpha treatment, or; ⋅If S1≤1, the patient is considered unlikely to have a clinical response to an anti-TNF alpha treatment, ⋅Lref being established on patients samples comprising a group (1) of patients with clinical improvement after treatment with TNF-alpha on the one hand, and a group (2) of patients who did not show any clinical improvement after treatment with TNF-alpha on the other hand, each of the groups (1) and (2) comprising at least 60 patients, by measuring the level of Burkholderiales at M0 in each of these groups, and determining the Lref value as the mean value separating patients from group (1) of patients in group (2). It also relates to an ex vivo method for predicting anti-TNF alpha response in a patient with an inflammatory disease in which this treatment is generally indicated, and to the use of at least one bacteria selected from the group comprising Burkholderiales, Serratia marcescens , Klebsiella oxytoca, Enterococcus gallinarum, Weissella cibaria and Coprococcus eutactus, as a predictive biomarker of the clinical outcome of an anti-TNF alpha treatment in an inflammatory disease.