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公开(公告)号：US20080071385A1
公开(公告)日：2008-03-20
申请号：US11947384
申请日：2007-11-29
Applicant: Francois Binette , Joseph Hammer , Krish Mukhopadhyay , Joel Rosenblatt
Inventor： Francois Binette , Joseph Hammer , Krish Mukhopadhyay , Joel Rosenblatt
IPC: A61F2/08
CPC classification number: A61L27/3604 , A61L27/3683 , A61L27/38 , A61L27/3852 , A61L27/58
Abstract: A conformable tissue implant is provided for use in repairing or augmenting a tissue defect or injury site. The tissue implant contains a tissue carrier matrix comprising a plurality of biocompatible, bioresorbable granules and at least one tissue fragment in association with the granules. The tissue fragment contains one or more viable cells that can migrate from the tissue and populate the tissue carrier matrix. Also provided is a method for injectably delivering the tissue implant.
Abstract translation: 提供适合组织植入物用于修复或增加组织缺损或损伤部位。 组织植入物包含组织载体基质，其包含多个生物相容的生物可再吸收的颗粒和与颗粒结合的至少一个组织片段。 组织片段含有一种或多种活细胞，其可以从组织迁移并填充组织载体基质。 还提供了用于可注射地递送组织植入物的方法。
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Patent Agency Ranking
12.发明申请Method of intra-operative coating therapeutic agents onto sutures, composite sutures and methods of use 审中-公开术中将治疗剂涂覆在缝合线上的方法，复合缝合线和使用方法公开(公告)号：US20060287676A1
公开(公告)日：2006-12-21
申请号：US11315905
申请日：2005-12-22
Applicant: Rita Prajapati , Steven Bowman , Mark Timmer , Patrick De Dyne , Joseph Hammer , Chunlin Yang
Inventor： Rita Prajapati , Steven Bowman , Mark Timmer , Patrick De Dyne , Joseph Hammer , Chunlin Yang
IPC: A61L17/00
CPC classification number: A61L17/145
Abstract: Intra-operative coating of sutures with therapeutic proteins, particularly growth factors such as rhGDF-5. including contacting a suture to a device containing a therapeutic agent, methods of repairing soft tissue defects with coated sutures and composite sutures coated with therapeutic agents.
Abstract translation: 用治疗性蛋白质，特别是生长因子例如rhGDF-5进行术中包衣。 包括使缝合线与包含治疗剂的装置接触，用涂覆的缝合线修复软组织缺陷的方法以及用治疗剂涂覆的复合缝合线。
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13.发明申请Method of intra-operative coating therapeutic agents onto sutures composite sutures and methods of use 审中-公开术中将治疗剂涂覆在缝线复合缝合线上的方法及使用方法公开(公告)号：US20060287675A1
公开(公告)日：2006-12-21
申请号：US11315793
申请日：2005-12-22
Applicant: Rita Prajapati , Steven Bowman , Mark Timmer , Patrick De Dyne , Joseph Hammer , Chunlin Yang
Inventor： Rita Prajapati , Steven Bowman , Mark Timmer , Patrick De Dyne , Joseph Hammer , Chunlin Yang
IPC: A61L17/00
CPC classification number: A61L17/145
Abstract: Intra-operative coating of sutures with therapeutic proteins, particularly growth factors such as rhGDF-5. including contacting a suture to a device containing a therapeutic agent, methods of repairing soft tissue defects with coated sutures and composite sutures coated with therapeutic agents.
Abstract translation: 用治疗性蛋白质，特别是生长因子例如rhGDF-5进行术中包衣。 包括使缝合线与包含治疗剂的装置接触，用涂覆的缝合线修复软组织缺陷的方法以及用治疗剂涂覆的复合缝合线。
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公开(公告)号：US20060286289A1
公开(公告)日：2006-12-21
申请号：US11153285
申请日：2005-06-15
Applicant: Rita Prajapati , Steven Bowman , Mark Timmer , Patrick De Deyne , Joseph Hammer , Chunlin Yang
Inventor： Rita Prajapati , Steven Bowman , Mark Timmer , Patrick De Deyne , Joseph Hammer , Chunlin Yang
IPC: A61F13/02
CPC classification number: A61B17/06166 , A61B2017/00889 , A61B2017/00893 , A61L17/145
Abstract: Intra-operative coating of sutures with therapeutic proteins, particularly growth factors such as rhGDF-5. including contacting a suture to a device containing a therapeutic agent.
Abstract translation: 用治疗性蛋白质，特别是生长因子例如rhGDF-5进行术中包衣。 包括将缝合线接触含有治疗剂的装置。
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公开(公告)号：US20050232967A1
公开(公告)日：2005-10-20
申请号：US10828838
申请日：2004-04-20
Applicant: Stephanie Kladakis , Joseph Hammer , Dhanuraj Shetty , Sridevi Dhanaraj
Inventor： Stephanie Kladakis , Joseph Hammer , Dhanuraj Shetty , Sridevi Dhanaraj
CPC classification number: A61L27/56 , A61F2/3872 , A61L27/18 , A61L2430/06 , C08L67/04
Abstract: A biocompatible meniscal repair device is disclosed. The tissue repair device includes a scaffold adapted to be placed in contact with a defect in a meniscus, the scaffold comprising a high-density, dry laid nonwoven polymeric material and a biocompatible foam. The scaffold provides increased suture pull-out strength.
Abstract translation: 公开了一种生物相容性半月板修复装置。 所述组织修复装置包括适于与弯液面中的缺陷接触的支架，所述支架包括高密度干法铺设的非织造聚合物材料和生物相容性泡沫。 支架提供增加的缝线拉拔强度。
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公开(公告)号：US20050113937A1
公开(公告)日：2005-05-26
申请号：US10723982
申请日：2003-11-26
Applicant: Francois Binette , Joseph Hammer , Krish Mukhopadhyay , Joel Rosenblatt
Inventor： Francois Binette , Joseph Hammer , Krish Mukhopadhyay , Joel Rosenblatt
CPC classification number: A61L27/3604 , A61L27/3683 , A61L27/38 , A61L27/3852 , A61L27/58
Abstract: A conformable tissue implant is provided for use in repairing or augmenting a tissue defect or injury site. The tissue implant contains a tissue carrier matrix comprising a plurality of biocompatible, bioresorbable granules and at least one tissue fragment in association with the granules. The tissue fragment contains one or more viable cells that can migrate from the tissue and populate the tissue carrier matrix. Also provided is a method for injectably delivering the tissue implant.
Abstract translation: 提供适合组织植入物用于修复或增加组织缺损或损伤部位。 组织植入物包含组织载体基质，其包含多个生物相容的生物可再吸收的颗粒和与颗粒结合的至少一个组织片段。 组织片段含有一种或多种活细胞，其可以从组织迁移并填充组织载体基质。 还提供了用于可注射地递送组织植入物的方法。
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