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公开(公告)号：US20170290436A1
公开(公告)日：2017-10-12
申请号：US15096217
申请日：2016-04-11
Applicant: Toby James Welsh
Inventor： Toby James Welsh
CPC classification number: H04R1/028 , A61H1/005 , A61H23/0236 , A61H2201/0157 , A61H2201/5048 , A61H2201/5097 , A61M21/02 , A61M2021/0022 , A61M2021/0027 , A61M2205/3561 , A61M2205/3584 , H04R5/02 , H04R2201/028 , H04R2400/03
Abstract: This Invention is designed to provide relaxation and sound healing properties to person while they practice seated meditation on a low profile and portable platform. The platform can play stereo sounds while transferring the sounds resonant vibrations to the user via direct contact to the platforms top surface. This is achieved by a combination of any top surface material capable of resonating such as wood or slate, which is also capable of supporting the user and the use of powered sound exciters designed for the sole purpose of producing sound via connection to such a surface. This platform is primarily designed to enhance the practice of meditation to help reduce stress and create a deep sense of relaxation peace and well being.
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公开(公告)号：US08552018B2
公开(公告)日：2013-10-08
申请号：US13051790
申请日：2011-03-18
Applicant: Laurence H. Hurley , Daruka Mahadevan , David J. Bearss , Hariprasad Vankayalapati , Sridevi Bashyam , Steven L. Warner , James Welsh
Inventor： Laurence H. Hurley , Daruka Mahadevan , David J. Bearss , Hariprasad Vankayalapati , Sridevi Bashyam , Steven L. Warner , James Welsh
IPC: A61K31/519 , A61K31/496 , A61P35/04 , C07D491/14 , C07D471/14 , C07D239/70 , A61K31/517
CPC classification number: A61K31/519 , A61K45/06 , A61N5/00 , C07D403/14 , C07D405/14 , C07D487/04 , C07D491/048 , C07D495/04 , C07D495/14
Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
Abstract translation: 公开了可用于治疗蛋白激酶介导的疾病和病症（例如癌症）的蛋白激酶抑制剂。 本发明化合物具有以下结构：包括立体异构体，前体药物和药学上可接受的盐，其中A是选自以下的环部分：其中R1，R2，R3，X，Z，L1，Cyc11，L2和Cyc22为 本文定义。 还公开了含有本发明化合物的组合物以及与其用途有关的方法。
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公开(公告)号：US640022A
公开(公告)日：1899-12-26
申请号：US1899734374
申请日：1899-10-21
Applicant: PEPPER JAMES WELSH
Inventor： PEPPER JAMES WELSH
CPC classification number: A47C17/40
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Patent Agency Ranking
公开(公告)号：US20090124635A1
公开(公告)日：2009-05-14
申请号：US11813852
申请日：2006-01-12
Applicant: Christopher Gordon Barber , David Clive Blakemore , David Cameron Pryde , James Welsh Auld Kinnaird
Inventor： Christopher Gordon Barber , David Clive Blakemore , David Cameron Pryde , James Welsh Auld Kinnaird
IPC: A61K31/4545 , C07D401/14 , A61K31/506 , A61P31/12 , A61P37/00 , A61P29/00 , A61P31/18 , C07D405/14
CPC classification number: C07D405/14 , C07D401/14
Abstract: The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, R5, m and n are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
Abstract translation: 本发明提供式（I）化合物，其中R 1，R 2，R 3，R 4，R 5，m和n如上所定义。 本发明的化合物是趋化因子CCR5受体活性的调节剂，特别是拮抗剂。 CCR5受体的调节剂可用于治疗各种炎性疾病和病症，以及用于治疗HIV和遗传相关逆转录病毒的感染。
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公开(公告)号：US20090099165A1
公开(公告)日：2009-04-16
申请号：US11735344
申请日：2007-04-13
Applicant: Laurence H. Hurley , Daruka Mahadevan , Haiyong Han , David J. Bearss , Hariprasad Vankayalapati , Sridevi Bashyam , Ruben M. Munoz , Steven L. Warner , Kimiko Della Croce , Daniel D. Von Hoff , Cory L. Grand , James Welsh
Inventor： Laurence H. Hurley , Daruka Mahadevan , Haiyong Han , David J. Bearss , Hariprasad Vankayalapati , Sridevi Bashyam , Ruben M. Munoz , Steven L. Warner , Kimiko Della Croce , Daniel D. Von Hoff , Cory L. Grand , James Welsh
IPC: A61K31/5377 , C07D487/04 , A61K31/519
CPC classification number: A61K31/519 , A61K45/06 , A61N5/00 , C07D403/14 , C07D405/14 , C07D487/04 , C07D491/048 , C07D495/04 , C07D495/14
Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
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公开(公告)号：US20080051414A1
公开(公告)日：2008-02-28
申请号：US11680921
申请日：2007-03-01
Applicant: Laurence Hurley , Daruka Mahadevan , Haiyong Han , David Bearss , Hariprasad Vankayalapati , Sridevi Bashyam , Ruben Munoz , Steven Warner , Kimiko Della Croce , Daniel Von Hoff , Cory Grand , James Welsh
Inventor： Laurence Hurley , Daruka Mahadevan , Haiyong Han , David Bearss , Hariprasad Vankayalapati , Sridevi Bashyam , Ruben Munoz , Steven Warner , Kimiko Della Croce , Daniel Von Hoff , Cory Grand , James Welsh
IPC: A61K31/496 , A61P35/00 , A61P43/00 , C07D241/04 , C07D401/14 , C07D403/02 , C07D471/04
CPC classification number: C07D487/04 , C07D403/14 , C07D405/14 , C07D491/048 , C07D495/04 , C07D495/14
Abstract: Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from: and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
Abstract translation: 公开了可用于治疗蛋白激酶介导的疾病和病症（例如癌症）的蛋白激酶抑制剂。 本发明的化合物具有以下结构：包括立体异构体，其前药和药学上可接受的盐，其中A是选自以下的环部分：其中R 1，R 2，R 3，X，Z，L 1，Cyc 11， L 2和Cyc 2如本文所定义。 还公开了含有本发明化合物的组合物以及与其用途有关的方法。
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17.发明授权Separator for impurities present in the combustion products of gas turbine plants 失效燃气轮机厂燃烧产物中存在的杂质分离器
公开(公告)号：US2659448A
公开(公告)日：1953-11-17
申请号：US17729550
申请日：1950-08-02
Applicant: JAMES WELSH ROBERT
Inventor： JAMES WELSH ROBERT
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公开(公告)号：US640021A
公开(公告)日：1899-12-26
申请号：US1899732188
申请日：1899-09-30
Applicant: PEPPER JAMES WELSH
Inventor： PEPPER JAMES WELSH
CPC classification number: A47C17/40
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