Transporting device with drag reduction dimples
    15.
    发明申请
    Transporting device with drag reduction dimples 审中-公开
    带减阻凹坑的运输装置

    公开(公告)号:US20060066132A1

    公开(公告)日:2006-03-30

    申请号:US10954518

    申请日:2004-09-30

    申请人: John Page

    发明人: John Page

    IPC分类号: B62D25/02

    CPC分类号: B62D35/00

    摘要: A device that transports people or cargo or equipment that has an exterior surface that has a plurality of closely spaced apart dimple depressions on some or all its surfaces whereby they reduce the surface tension stickiness on said surfaces when said devise moves through water, air or on snow or ice.

    摘要翻译: 运输人员或货物或设备,其外表面在其一些或全部表面上具有多个紧密间隔开的凹陷凹陷,从而当所述设备移动通过水,空气或其上时,它们减小了所述表面上的表面张力粘性 雪或冰。

    Aircraft converts drag to lift
    16.
    发明申请
    Aircraft converts drag to lift 审中-公开
    飞机将拖曳转换为电梯

    公开(公告)号:US20050116087A1

    公开(公告)日:2005-06-02

    申请号:US10460275

    申请日:2003-06-11

    申请人: John Page

    发明人: John Page

    摘要: An aircraft that has a fuselage that has a majority of its frontal surface areas that strike air angled to deflect air down and cause an upward lift on said fuselage and a propulsion means attached to the fuselage on a different angle than the angle of the fuselage thereby causing the bottom of the fuselage to have an angle of attack into the wind like a conventional wing thereby contributing to the lift of the aircraft.

    摘要翻译: 具有机身的飞机具有大部分的前部表面区域,其大致角度使空气向下偏转,并使所述机身上升并且以与机身的角度不同的角度附接到机身上的推进装置 导致机身的底部像传统的机翼一样具有迎风的风险,从而有助于飞机的升降。

    Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
    17.
    发明授权
    Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors 失效
    双环杂芳族化合物作为蛋白酪氨酸激酶抑制剂

    公开(公告)号:US06169091A

    公开(公告)日:2001-01-02

    申请号:US09051324

    申请日:1998-08-26

    IPC分类号: C07D48704

    CPC分类号: C07D471/04 C07D495/04

    摘要: Substituted heteroaromatic compounds of formula (A) wherein X is N or CH; in which (a) represents a fused 5, 6 or 7-membered heterocyclic ring and R3 is a group ZR4 wherein Z is joined to R4 through a (CH2)p group in which p is 0, 1, or 2 and Z represents a group V(CH2), V(CF2), (CH2)V, (CF2)V, V(CRR′), V(CHR) or V where R and R′ are each C1-4 alkyl and in which V is a hydrocarbyl group containing 0, 1 or 2 carbon atoms, carbonyl, dicarbonyl, CH(OH), CH(CN), sulphonamide, amide, O, S(O)m or NRb where Rb is hydrogen or Rb is C1-4 alkyl; and R4 is an optionally substituted C3-6 cycloalkyl or an optionally substituted 5, 6, 7, 8, 9 or 10-membered carbocyclic or heterocyclic moiety; or R3 is a group ZR4 in which Z is NRb, and NRb and R4 together form an optionally substituted 5, 6, 7, 8, 9 or 10-membered carbocyclic or heterocyclic moiety, are protein tyrosine kinase inhibitors. The compounds are described, as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in the treatment of psoriasis, fibrosis, atherosclerosis, restenosis, auto-immune disease, allergy, asthma, transplantation rejection, inflammation, thrombosis, nervous system diseases, and cancer.

    摘要翻译: 取代的式(A)的杂芳族化合物,其中X是N或CH; 其中(a)表示稠合的5,6或7-元杂环,R3是基团ZR4,其中Z通过其中p为0,1或2的(CH 2)p基团连接到R 4,Z表示 组V(CH 2),V(CF 2),(CH 2)V,(CF 2)V,V(CRR'),V(CHR)或V其中R和R'各自是C 1-4烷基,其中V是 羰基,二羰基,CH(OH),CH(CN),磺酰胺,酰胺,O,S(O)m或NR b,其中R b是氢或R b是C 1-4烷基; 并且R 4是任选取代的C 3-6环烷基或任选取代的5,6,7,8,9或10元碳环或杂环部分; 或R3是Z Z4,其中Z是NRb,NRb和R4一起形成任选取代的5,6,7,8,9或10元碳环或杂环部分是蛋白质酪氨酸激酶抑制剂。 描述了这些化合物,以及其制备方法,包括这些化合物的药物组合物及其在医学中的用途,例如治疗牛皮癣,纤维化,动脉粥样硬化,再狭窄,自身免疫疾病,变态反应,哮喘,移植排斥,炎症 ,血栓形成,神经系统疾病和癌症。