公开(公告)号：US20220395521A1

公开(公告)日：2022-12-15

申请号：US17579067

申请日：2022-01-19

Applicant: Kaleido Biosciences, Inc.

Inventor： Geoffrey A. von Maltzahn ,  John M. Geremia

IPC: A61K31/7004 ,  A61K45/06 ,  A61K31/19 ,  A61K31/197 ,  A61K31/198 ,  A61K31/192 ,  A61K31/733 ,  A61K31/702 ,  A61K31/716 ,  A61K9/00 ,  A61K31/047 ,  A61K31/7016 ,  A61K35/741 ,  C12Q1/10

Abstract: Compositions comprising microbiome regulators are provided, as well as methods of using the same for the modulation of the human microbiota and to treat or prevent related diseases, disorders, or conditions.

公开(公告)号：US20210161942A1

公开(公告)日：2021-06-03

申请号：US16630116

申请日：2018-07-13

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jacob Rosenblum Rubens

IPC: A61K31/715 ,  A61K45/06

Abstract: Compositions, e.g., pharmaceutical compositions, nutritional compositions, medical foods, and food ingredients, as well as their methods of use, are provided, for modulating exogenous substances, enzyme activities, and drug activities.

公开(公告)号：US20210113596A1

公开(公告)日：2021-04-22

申请号：US16883107

申请日：2020-05-26

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/702 ,  A61K45/06 ,  A61K31/716 ,  A61K31/733 ,  A61P1/00 ,  A61K31/09 ,  A61K31/11 ,  A61K31/12 ,  A61K31/165 ,  A61K31/34 ,  A61K31/353 ,  A61K31/365 ,  A61K31/366 ,  A61K31/7034 ,  A61K31/7048 ,  A61K31/706 ,  A61K31/715 ,  A23L33/10 ,  A23P10/00 ,  A61K31/7004 ,  A61K31/7016 ,  A61K35/741

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

公开(公告)号：US20190290675A1

公开(公告)日：2019-09-26

申请号：US16466945

申请日：2017-12-06

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Molly Krisann Gibson ,  Christopher Matthew Liu ,  Geoffrey A. von Maltzahn ,  Han Yuan

IPC: A61K31/716 ,  A61K9/00 ,  A61P3/00

Abstract: Compositions of glycan polymers and methods of making and manufacturing the same are described herein. Also provided are methods of treating a disease or disorder with a glycan polymer preparation.

公开(公告)号：US10314853B2

公开(公告)日：2019-06-11

申请号：US15624372

申请日：2017-06-15

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Jared Silverman ,  Yvonne J. Yamanaka ,  John Miles Milwid ,  John M. Geremia

IPC: A61K31/702 ,  A61K31/716 ,  A23P10/00 ,  A61K45/06 ,  A61K35/741 ,  A23L33/10 ,  A61K31/7016 ,  A61K31/7004 ,  A61K31/733 ,  A61P1/00 ,  A61K35/00

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.

公开(公告)号：US20190091249A1

公开(公告)日：2019-03-28

申请号：US16140091

申请日：2018-09-24

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Yvonne J. Yamanaka ,  Jared Silverman ,  John Miles Milwid ,  Jacob Rosenblum Rubens ,  John M. Geremia

IPC: A61K31/702 ,  A61K35/741 ,  A23L33/135 ,  A61P35/04 ,  A61P43/00 ,  A23L33/125 ,  A61P1/00 ,  A61K31/716 ,  A61K31/733 ,  A61P35/00 ,  A61K45/06 ,  A61P3/02

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said gycan therapeutics, e.g. in cancer therapy.

公开(公告)号：US20180296582A1

公开(公告)日：2018-10-18

申请号：US15568251

申请日：2016-04-23

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  John M. Geremia

IPC: A61K31/7004 ,  A61K9/00 ,  A61K35/741 ,  C12Q1/10 ,  A61K45/06 ,  A61K31/7016 ,  A61K31/047 ,  A61K31/19 ,  A61K31/198 ,  A61K31/197

Abstract: Compositions comprising microbiome regulators are provided, as well as methods of using the same for the modulation of the human microbiota and to treat or prevent related diseases, disorders, or conditions.

公开(公告)号：US20180147221A1

公开(公告)日：2018-05-31

申请号：US15568243

申请日：2016-04-23

Applicant: KALEIDO BIOSCIENCES, INC.

Inventor： Geoffrey A. von Maltzahn ,  Yvonne J. Yamanaka ,  Jared Silverman ,  Jack Milwid ,  Jacob R. Rubens ,  John M. Geremia

IPC: A61K31/702 ,  A61P43/00 ,  A61K35/741 ,  A61P35/00 ,  A61P1/00 ,  A61P3/02 ,  A61K45/06 ,  A61P35/04 ,  A23L33/125 ,  A23L33/135

CPC classification number: A61K31/702 ,  A23L33/125 ,  A23L33/135 ,  A23V2002/00 ,  A61K31/716 ,  A61K31/733 ,  A61K35/741 ,  A61K45/06 ,  A61P1/00 ,  A61P3/02 ,  A61P35/00 ,  A61P35/04 ,  A61P43/00

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said gycan therapeutics, e.g. in cancer therapy.

公开(公告)号：US20210401861A1

公开(公告)日：2021-12-30

申请号：US17363597

申请日：2021-06-30

Applicant: Kaleido Biosciences, Inc.

Inventor： Geoffrey A. von Maltzahn ,  Yvonne J. Yamanaka ,  Jared Silverman ,  John Miles Milwid ,  Jacob Rosenblum Rubens ,  John M. Geremia

IPC: A61K31/702 ,  A61K45/06 ,  A61K31/716 ,  A61K31/733 ,  A23L33/125 ,  A23L33/135 ,  A61P3/02 ,  A61P43/00 ,  A61P1/00 ,  A61P35/04 ,  A61P35/00 ,  A61K35/741

Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said glycan therapeutics, e.g. in cancer therapy.

公开(公告)号：US20210395284A1

公开(公告)日：2021-12-23

申请号：US17292119

申请日：2019-11-08

Applicant: DSM IP Assets B.V. ,  Midori USA, Inc. ,  KALEIDO BIOSCIENCES, INC.

Inventor： Manuela BAUR ,  Estel CANET-MARTINEZ ,  Ruediger HAINZ ,  Ulrich HOELLER ,  Lisa Ann LAPRADE ,  John Michael GEREMIA ,  Ghislain SCHYNS

IPC: C07H1/00 ,  C07H3/06

Abstract: The present disclosure relates oligosaccharide preparations suitable for use in nutritional compositions such as animal feed and methods of manufacturing the described oligosaccharide preparations. The present disclosure further relates to nutritional compositions that comprise the oligosaccharide preparations. The disclosed oligosaccharide preparations can be advantageous as an animal feed due to, at least in part, their prebiotic utility and the presence of anhydro-subunit containing oligosaccharides, which can be used to detect and/or determine the presence and content of the disclosed oligosaccharide preparations in the nutritional composition.