DETECTION METHOD FOR NOVEL ROS1 FUSIONS
    11.
    发明申请
    DETECTION METHOD FOR NOVEL ROS1 FUSIONS 有权
    新型ROS1融合检测方法

    公开(公告)号:US20130102006A1

    公开(公告)日:2013-04-25

    申请号:US13805513

    申请日:2011-06-22

    Abstract: Polynucleotides which are novel causative genes for cancer are elucidated, and a detection method of the polynucleotides or polypeptides encoded by the polynucleotides, and a kit and a primer set for detection are provided, based on the knowledge gained by the elucidation. In the detection method, a fusion gene comprising part of an SDC4, CD74, EZR, SLC34A2, LRIG3, or TPM3 gene and part of a ROS1 gene, or a fusion protein encoded by the fusion gene is detected. The primer set or the detection kit comprises a sense primer designed based on a portion encoding SDC4, CD74, EZR, SLC34A2, LRIG3, or TPM3 and an antisense primer designed based on a portion encoding ROS1.

    Abstract translation: 阐明了作为癌症的新型致病基因的多核苷酸,并且基于通过阐明获得的知识,提供了由多核苷酸编码的多核苷酸或多肽的检测方法以及用于检测的试剂盒和引物组。 在检测方法中,检测包含SDC4,CD74,EZR,SLC34A2,LRIG3或TPM3基因和部分ROS1基因的融合基因或融合基因编码的融合蛋白。 引物组或检测试剂盒包括基于编码SDC4,CD74,EZR,SLC34A2,LRIG3或TPM3的部分设计的有义引物和基于编码ROS1的部分设计的反义引物。

    Control device and method for camera unit and program for implementing the control method
    12.
    发明授权
    Control device and method for camera unit and program for implementing the control method 有权
    用于摄像机单元的控制装置和方法以及用于实现控制方法的程序

    公开(公告)号:US07965935B2

    公开(公告)日:2011-06-21

    申请号:US12142033

    申请日:2008-06-19

    Applicant: Kengo Takeuchi

    Inventor: Kengo Takeuchi

    CPC classification number: H04N5/232 H04N5/23216 H04N5/23296

    Abstract: A camera unit which is capable of coping with both a case where it is largely displaced from a preset position and a case where it is slightly displaced from the same, and makes it possible to enhance accuracy and reliability in displacement correction. A zoom/focus control circuit and a pan/tilt control circuit drive the camera unit. A memory stores preset information indicative of a shooting position and a focal length of the camera unit. A correction image memory stores correction images shot at different focal lengths at the shooting position. An image comparison circuit compares between an image shot by the camera unit at the shooting position and the stored correction images, and calculates a displacement amount. A CPU corrects the driving amount of the pan/tilt control circuit based on the calculated displacement amount.

    Abstract translation: 能够应对从预设位置大幅度偏离的情况的摄像机单元以及稍微从其偏移的情况,能够提高位移校正的精度和可靠性。 变焦/对焦控制电路和摇摄/倾斜控制电路驱动相机单元。 存储器存储指示摄像单元的拍摄位置和焦距的预设信息。 校正图像存储器存储在拍摄位置处以不同焦距拍摄的校正图像。 图像比较电路将拍摄位置处的摄像机单元拍摄的图像与存储的校正图像进行比较,并计算位移量。 CPU根据计算出的位移量来校正摇摄/倾斜控制电路的驱动量。

    Microscope System, Specimen Observing Method, and Computer Program Product
    13.
    发明申请
    Microscope System, Specimen Observing Method, and Computer Program Product 审中-公开
    显微镜系统,样本观察方法和计算机程序产品

    公开(公告)号:US20100141752A1

    公开(公告)日:2010-06-10

    申请号:US12629547

    申请日:2009-12-02

    Abstract: A microscope system includes an image acquiring unit that acquires a specimen image formed by capturing a specimen multi-stained by a plurality of pigments using a microscope; a pigment amount acquiring unit that acquires a pigment amount of each pigment staining a corresponding position on the specimen, for each pixel of the specimen image; and a pigment selecting unit that selects a display target pigment from the plurality of pigments. The system also includes a display image generating unit that generates a display image where a staining state of the specimen by the display target pigment is displayed, on the basis of the pigment amount of the display target pigment in each pixel of the specimen image; and a display processing unit that displays the display image on a display unit.

    Abstract translation: 显微镜系统包括图像获取单元,其获取通过使用显微镜捕获多个颜料多染色的样本而形成的标本图像; 颜料量获取单元,针对样本图像的每个像素获取每个颜料的颜料量染色样品上的相应位置; 以及颜料选择单元,其从多种颜料中选择显示目标颜料。 该系统还包括显示图像生成单元,其基于样本图像的每个像素中的显示目标颜料的颜料量,生成显示目标颜料的样品的染色状态的显示图像; 以及显示处理单元,其将显示图像显示在显示单元上。

    RECORDING APPARATUS AND RECORDING METHOD
    14.
    发明申请
    RECORDING APPARATUS AND RECORDING METHOD 审中-公开
    记录装置和记录方法

    公开(公告)号:US20070266408A1

    公开(公告)日:2007-11-15

    申请号:US11744363

    申请日:2007-05-04

    Applicant: Kengo Takeuchi

    Inventor: Kengo Takeuchi

    Abstract: A recording apparatus includes a recording unit, a determination unit, a generation unit, an identification unit, and a control unit. The recording unit records image data on a recording medium. The determination unit determines plural recording media to be allocated to a same group. The generation unit generates order information indicating an order of each recording medium in the group. The order information includes identification information identifying each recording medium. The identification unit identifies a recording medium in the group based on the identification information. The control unit controls the recording unit to record, on each of the plural recording media belonging to the same group, information representing an order of the identified recording medium in the group and information representing a total number of the recording media belonging to the same group, based on an identification result obtained by the identification unit and the order information.

    Abstract translation: 记录装置包括记录单元,确定单元,生成单元,识别单元和控制单元。 记录单元将图像数据记录在记录介质上。 确定单元确定要分配给同一组的多个记录介质。 生成单元生成表示组中的每个记录介质的顺序的顺序信息。 订单信息包括识别每个记录介质的识别信息。 识别单元基于识别信息识别组中的记录介质。 控制单元控制记录单元在属于同一组的多个记录介质中的每一个上记录表示组中所识别的记录介质的顺序的信息和表示属于同一组的记录介质的总数的信息 基于由识别单元获得的识别结果和订单信息。

    RECORDING APPARATUS AND RECORDING METHOD
    15.
    发明申请
    RECORDING APPARATUS AND RECORDING METHOD 审中-公开
    记录装置和记录方法

    公开(公告)号:US20070263988A1

    公开(公告)日:2007-11-15

    申请号:US11744371

    申请日:2007-05-04

    Applicant: Kengo Takeuchi

    Inventor: Kengo Takeuchi

    Abstract: A recording apparatus includes a recording format selection unit configured to select one of a plurality of recording formats, an initialization unit configured to initialize a loaded recording medium, a recording unit configured to record image data on the loaded recording medium, and a mode switching unit configured to switch between an ordinary recording mode that enables the initialization unit to initialize a newly loaded recording medium based on a recording format selected by the selection unit independent of a recording format selected for a preceding recording medium and a relay recording mode that enables the initialization unit to initialize a newly loaded recording medium, if loaded after a preceding recording medium, based on a recording format selected for the preceding recording medium.

    Abstract translation: 记录装置包括被配置为选择多种记录格式之一的记录格式选择单元,被配置为初始化加载的记录介质的初始化单元,被配置为在加载的记录介质上记录图像数据的记录单元和模式切换单元 被配置为在能够使初始化单元基于由选择单元选择的记录格式来初始化新加载的记录介质的普通记录模式之间切换,独立于为先前记录介质选择的记录格式,以及启用初始化的中继记录模式 单元,用于根据为先前的记录介质选择的记录格式,在前一记录介质之后加载新加载的记录介质。

    Detection method for novel ROS1 fusions
    16.
    发明授权
    Detection method for novel ROS1 fusions 有权
    新型ROS1融合检测方法

    公开(公告)号:US09109259B2

    公开(公告)日:2015-08-18

    申请号:US13805513

    申请日:2011-06-22

    Abstract: Polynucleotides which are novel causative genes for cancer are elucidated, and a detection method of the polynucleotides or polypeptides encoded by the polynucleotides, and a kit and a primer set for detection are provided, based on the knowledge gained by the elucidation. In the detection method, a fusion gene comprising part of an SDC4, CD74, EZR, SLC34A2, LRIG3, or TPM3 gene and part of a ROS1 gene, or a fusion protein encoded by the fusion gene is detected. The primer set or the detection kit comprises a sense primer designed based on a portion encoding SDC4, CD74, EZR, SLC34A2, LRIG3, or TPM3 and an antisense primer designed based on a portion encoding ROS1.

    Abstract translation: 阐明了作为癌症的新型致病基因的多核苷酸,并且基于通过阐明获得的知识,提供了由多核苷酸编码的多核苷酸或多肽的检测方法以及用于检测的试剂盒和引物组。 在检测方法中,检测包含SDC4,CD74,EZR,SLC34A2,LRIG3或TPM3基因和部分ROS1基因的融合基因或融合基因编码的融合蛋白。 引物组或检测试剂盒包括基于编码SDC4,CD74,EZR,SLC34A2,LRIG3或TPM3的部分设计的有义引物和基于编码ROS1的部分设计的反义引物。

    Focus detecting apparatus and control method thereof
    17.
    发明授权
    Focus detecting apparatus and control method thereof 有权
    焦点检测装置及其控制方法

    公开(公告)号:US08704941B2

    公开(公告)日:2014-04-22

    申请号:US13307227

    申请日:2011-11-30

    Applicant: Kengo Takeuchi

    Inventor: Kengo Takeuchi

    Abstract: An external AF focus detecting apparatus capable of achieving both good focus detection accuracy for a subject in a short distance and an appropriate amount of processing for a subject in a long distance is provided. In the case where the distance to the subject is less than a predetermined threshold value, with respect to accumulation pixels SA5 to SA25 selected in one of a pair of line sensors, pixels are selected in the other line sensor so as to include more pixels in the direction of shift of an optical image of a field of view, namely, pixels SB5 to SB29 are selected as accumulation pixels. Alternatively, pixels included in a range obtained by shifting by a predetermined number of pixels from the range of the accumulation pixels that have been selected in the one line sensor are selected as the accumulation pixels in the other line sensor.

    Abstract translation: 提供一种外部AF焦点检测装置,其能够实现短距离的被摄体的良好的聚焦检测精度和对于长距离的被摄体的适当的处理量。 在与被摄体的距离小于预定阈值的情况下,对于在一对线传感器之一中选择的累积像素SA5〜SA25,在另一行传感器中选择像素,以包含更多的像素 选择视场的光学图像的移动方向,即像素SB5至SB29,作为累加像素。 或者,选择包含在通过从在一行传感器中选择的累积像素的范围内移动预定数量的像素而获得的范围中的像素作为另一行传感器中的累加像素。

    FOCUS DETECTION APPARATUS
    18.
    发明申请
    FOCUS DETECTION APPARATUS 有权
    聚焦检测装置

    公开(公告)号:US20120327291A1

    公开(公告)日:2012-12-27

    申请号:US13526827

    申请日:2012-06-19

    Applicant: Kengo Takeuchi

    Inventor: Kengo Takeuchi

    CPC classification number: H04N5/23212

    Abstract: A pixel selection unit sets an area based on a detection result of a contrast detection unit, in a case where it is determined that reliability of a focusing state detected by a phase difference detection unit is low.

    Abstract translation: 在确定由相位差检测单元检测到的聚焦状态的可靠性低的情况下,像素选择单元基于对比度检测单元的检测结果设置区域。

    MEDICAL DIAGNOSIS SUPPORT DEVICE, IMAGE PROCESSING METHOD, IMAGE PROCESSING PROGRAM, AND VIRTUAL MICROSCOPE SYSTEM
    19.
    发明申请
    MEDICAL DIAGNOSIS SUPPORT DEVICE, IMAGE PROCESSING METHOD, IMAGE PROCESSING PROGRAM, AND VIRTUAL MICROSCOPE SYSTEM 审中-公开
    医学诊断支持设备,图像处理方法,图像处理程序和虚拟显微镜系统

    公开(公告)号:US20100322502A1

    公开(公告)日:2010-12-23

    申请号:US12816472

    申请日:2010-06-16

    Abstract: The present invention provides a medical diagnosis support device, which is capable of acquiring information to support medical diagnosis for easily and precisely determining chromosome abnormality and/or gene amplification related to cancer or genetic disorder.The medical diagnosis support device for acquiring information to support medical diagnosis from an image of a specimen stained by multiple staining, the image is obtained by photographing the stained specimen with transmitted light, the device comprises: staining characteristics quantity acquisition means for acquiring characteristics quantity of each staining, based on a pixel value of the image of the stained specimen; marker intensifying means for intensifying a marker, based on the characteristics quantity of each staining thus acquired; marker extracting means for extracting the marker of each staining, based on the characteristics quantity in which the marker has been thus intensified; marker state judging means for judging a state of the marker, based on the marker of each staining thus extracted; and marker state identifying and displaying means for identifying and displaying the marker state, based on the judgment result.

    Abstract translation: 本发明提供一种能够获取信息以支持医学诊断以容易且精确地确定与癌症或遗传疾病相关的染色体异常和/或基因扩增的医学诊断支持装置。 用于从通过多次染色染色的样本的图像获取用于支持医学诊断的信息的医疗诊断支持装置,通过用透射光拍摄染色的样本获得图像,该装置包括:用于获取特征量的染色特征量获取装置 每次染色,基于染色标本的图像的像素值; 基于如此获得的每个染色的特征量来增强标记物的标记增强装置; 标记提取装置,用于基于标记已被强化的特征量提取每个染色的标记物; 标记状态判断装置,用于基于如此提取的每个染色的标记来判断标记的状态; 以及标记状态识别和显​​示装置,用于基于判断结果来识别和显示标记状态。

    Recording apparatus
    20.
    发明授权
    Recording apparatus 有权
    记录装置

    公开(公告)号:US07463815B2

    公开(公告)日:2008-12-09

    申请号:US10546755

    申请日:2004-02-19

    Applicant: Kengo Takeuchi

    Inventor: Kengo Takeuchi

    Abstract: In a recording apparatus that is capable of recording information on a plurality of recording media, i.e., first and second memory cards, the information is recorded on the first and second memory cards simultaneously, the information that has been recorded only on one of the memory cards is left and the information recorded on the other is deleted in dependence upon the available capacities of the memory cards at the end of recording. Performing recording in this manner makes it possible to store continuous data collectively on a single recording medium to the greatest extent possible.

    Abstract translation: 在能够在多个记录介质(即,第一和第二存储卡)上记录信息的记录装置中,信息被同时记录在第一和第二存储卡上,仅在存储器之一上记录的信息 剩下的是卡,并且根据记录结束时的存储卡的可用容量,删除另一个记录的信息。 以这种方式执行记录使得可以将连续数据集中地存储在单个记录介质上最大可能。

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