公开(公告)号：US12121920B2

公开(公告)日：2024-10-22

申请号：US16343404

申请日：2017-11-06

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Shu-Pin Hsieh ,  Yi-Tong Chen ,  Yi-Ting Lin ,  Po-Chuan Chen

IPC: B05B1/02 ,  A61M11/00 ,  A61M15/00 ,  A61M31/00 ,  B05B1/10 ,  B05B1/26 ,  B05B1/34 ,  B05B11/10 ,  B05B11/00

CPC classification number: B05B11/109 ,  A61M11/003 ,  A61M15/0065 ,  A61M15/009 ,  A61M31/00 ,  B05B1/02 ,  B05B1/10 ,  B05B1/26 ,  B05B1/34 ,  B05B11/1074 ,  A61M11/007 ,  A61M2205/0216 ,  A61M2205/0222 ,  A61M2205/0238 ,  A61M2205/121 ,  A61M2207/00 ,  A61M2210/0625 ,  B05B11/0038

Abstract: A microstructured passage module for aerosolizer is disclosed. The module includes a plate overlaid by a cover, an entrance, an exit, a plurality of protrusions and a plurality of pillars. The protrusions and pillars project from and are integral parts of the plate. Further, the plate can be divided into a first zone proximate to the entrance and a second zone proximate to the exit. The protrusions are arranged into parallel rows in a direction from the entrance to the exit and form parallel passages therebetween in the first zone for the liquid to flow along. The protrusions in each column are spaced from one another by tunnels. The pillars are interposingly disposed in the second zone and define certain channels therebetween. Moreover, a plurality of pillars further disposed in the passages increase a flow resistance for the liquid flowing through the passages.

公开(公告)号：US11433225B2

公开(公告)日：2022-09-06

申请号：US16862699

申请日：2020-04-30

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Shu-Pin Hsieh ,  Ting-Kai Tsai

IPC: A61M37/00

Abstract: A microneedle structure and a biodegradable microneedle thereof are provided. The biodegradable microneedle defining a central axis includes a first step portion and a second step portion that is taperedly extending from the first step portion along the central axis. The biodegradable microneedle has a total height along the central axis and a maximum internal diameter along a direction perpendicular to the central axis. The total height is within a range of 380-430 μm, and an aspect ratio defined by the total height divided by the maximum internal diameter is within a range of 1.2-2.2. In a cross section of the biodegradable microneedle having the central axis, a part of the second step portion arranged away from the first step portion having a corner. The corner has an angle within a range of 65-100 degrees and faces toward the first step portion.

公开(公告)号：US20210322685A1

公开(公告)日：2021-10-21

申请号：US17258753

申请日：2019-11-08

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： CHIH-CHIEH LIN ,  CHIU-JU SHEN ,  YI-TING LIN ,  JO-LING WU

IPC: A61M15/00

Abstract: A locking mechanism for an aerosol drug delivery device includes a first housing, a second housing, a screw and a fastening member. The first housing has a contact portion and a fastening space formed beside the contact portion. The second housing is rotatably connected with the first housing and is capable of rotating relative to the first housing along a rotation axis. The screw is rotatably connected with the second housing and is capable of rotating relative to the second housing along a central axis parallel to the rotation axis. The fastening member is movably connected with the screw and capable of being driven by the screw to move toward the contact portion. The fastening member includes a fastening portion capable of being displaced when contacting with the contact portion and entering into the fastening space to limit the relative rotation between the first housing and the second housing.

公开(公告)号：US20210094059A1

公开(公告)日：2021-04-01

申请号：US16981755

申请日：2019-04-10

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： CHIH-WEI LU ,  CHEN-HSIANG SANG ,  LIANG-RERN KUNG ,  WEI-ZHE CAI ,  JO-LING WU ,  SHU-PIN HSIEH

IPC: B05B17/06 ,  A61M11/00

Abstract: A detachable atomizing device and a container thereof are provided. The container is detachably assembled to an atomizing assembly. The container includes a cup and a flexible film. The cup has an opening arranged at an end thereof, the flexible film covers the opening of the cup, and the flexible film has a tension region and an outer ring-shaped region that surrounds the tension region. The tension region has a plurality of atomizing holes having an average diameter within a range of 1 μm to 20 μm, and the outer ring-shaped region is attached to the cup. When the cup is assembled to the atomizing assembly, a tension value of the tension region of the flexible film is increased from an initial tension value to an atomizing tension value by being pressed from the atomizing assembly, and the atomizing holes of the tension region are configured to allow liquid to pass there-through and to be formed as aerosol mist having an average atomized particle diameter less than a predetermined value. Accordingly, the cup and the flexible film that often need to be replaced are isolated from the atomizing assembly, and an expensive vibrator is disposed in the atomizing assembly, so that the service life of the detachable atomizing device can be extended.

公开(公告)号：US20190247594A1

公开(公告)日：2019-08-15

申请号：US16343399

申请日：2017-11-06

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Shu-Pin HSIEH ,  Yi-Tong CHEN ,  Yi-Ting LIN ,  Po-Chuan CHEN ,  Chiu-Ju SHEN

IPC: A61M11/00 ,  A61M15/00 ,  B05B11/00

CPC classification number: A61M11/003 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/009 ,  A61M31/00 ,  A61M2205/0222 ,  A61M2205/0238 ,  A61M2207/00 ,  A61M2210/0625 ,  B05B1/02 ,  B05B1/34 ,  B05B11/0038 ,  B05B11/3074 ,  B05B11/309

Abstract: An apparatus suitable for pressurized liquid transfusion is disclosed. The apparatus includes a nozzle assembly enclosed by the combination of a casing and a check nut. The nozzle assembly includes an elastomeric ring and a nozzle received by the combination of a cap and a receptacle. The elastomeric ring surrounds the nozzle and a proper seal is created therebetween. The dimension of the internal contour of the elastomeric ring is a bit smaller than the nozzle. The elastomeric ring is stretched so as to receive the nozzle. Additional processing may be applied to the elastomeric ring to achieve a different type of proper seal. Pressurized liquid passes through the apparatus so as to be transfused. The aforementioned seal serves to avoid leakage or pressure loss at the apparatus so as to avoid undesired aerosolization effects of an aerosolizer the apparatus is installed in.

公开(公告)号：US20190240427A1

公开(公告)日：2019-08-08

申请号：US16343404

申请日：2017-11-06

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Shu-Pin HSIEH ,  Yi-Tong CHEN ,  Yi-Ting LIN ,  Po-Chuan CHEN

IPC: A61M11/00 ,  A61M15/00 ,  B05B1/02 ,  B05B1/34

CPC classification number: A61M11/003 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/009 ,  A61M31/00 ,  A61M2205/0222 ,  A61M2205/0238 ,  A61M2207/00 ,  A61M2210/0625 ,  B05B1/02 ,  B05B1/34 ,  B05B11/0038 ,  B05B11/3074 ,  B05B11/309

Abstract: A microstructured passage module for aerosolizer is disclosed. The module includes a plate overlaid by a cover, an entrance, an exit, a plurality of protrusions and a plurality of pillars. The protrusions and pillars project from and are integral parts of the plate. Further, the plate can be divided into a first zone proximate to the entrance and a second zone proximate to the exit. The protrusions are arranged into parallel rows in a direction from the entrance to the exit and form parallel passages therebetween in the first zone for the liquid to flow along. The protrusions in each column are spaced from one another by tunnels. The pillars are interposingly disposed in the second zone and define certain channels therebetween. Moreover, a plurality of pillars further disposed in the passages increase a flow resistance for the liquid flowing through the passages.

公开(公告)号：US20190117908A1

公开(公告)日：2019-04-25

申请号：US16097272

申请日：2017-07-19

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Shu-Pin HSIEH ,  Yi-Tong CHEN ,  Po-Chuan CHEN ,  Ting-Kai TSAI ,  Chih-Wei LU ,  Laurence Kao

IPC: A61M11/00

Abstract: An aerosol generating apparatus is disclosed. The apparatus includes a liquid container, an adaptor and a driving element. The liquid container includes a perforated membrane through which a liquid can permeate. The liquid container further includes a first mating element. The adaptor includes a second mating element. The driving element includes a piezoelectric element coupled to a substrate. The driving element is accommodated by the adaptor and the substrate includes an aperture and a projection. The first and second mating elements are adapted to detachably and slidably mate with each other such that the aperture of the substrate aligns proximately to the center of the perforated membrane. The first and second mating elements are further adapted for relative movement along a sliding axis. The projection is adapted to press against the perforated membrane.

公开(公告)号：US12059527B2

公开(公告)日：2024-08-13

申请号：US17147552

申请日：2021-01-13

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Hsin-Hua Tseng ,  Chih-Wei Lu ,  Chen-Hsiang Sang ,  Liang-Rern Kung ,  Jo-Ling Wu ,  Shu-Pin Hsieh

IPC: A61M16/00 ,  A61M15/00 ,  A61M16/14 ,  G08C23/02 ,  G10L25/51 ,  G16H20/13

CPC classification number: A61M16/024 ,  A61M15/0085 ,  A61M16/14 ,  G08C23/02 ,  G10L25/51 ,  G16H20/13 ,  A61M2016/0021 ,  A61M2205/3375

Abstract: A method and a circuit system for driving a nebulizer are provided. When the nebulizer receives acoustic waves, a control circuit extracts audio signals from the acoustic waves. Afterwards, the control circuit determines if the audio signals are within a predetermined frequency range, and can determine whether or not to drive a circuit to produce an aerosol based on the audio signals. Further, a volume of the acoustic waves can also be used to determine whether or not to produce the aerosol, and also determine an output rate of the aerosol. The circuit system of the nebulizer includes an audio receiver for receiving the acoustic waves, an aerosol generator for producing the aerosol, and the control circuit used to control a driving circuit of the aerosol generator to drive a vibrational element to produce the aerosol through vibration in response to the audio signals and the volume.

公开(公告)号：US11944746B2

公开(公告)日：2024-04-02

申请号：US16759739

申请日：2018-11-05

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： Chiu-Ju Shen ,  Po Chuan Chen ,  Jo Ling Wu

IPC: A61M15/00 ,  A61M11/00

CPC classification number: A61M15/0065 ,  A61M11/007 ,  A61M2202/0468

Abstract: A fluid delivery apparatus comprises a first piston body, a second piston body, a fluid delivery pipe, and a sealing element. The first piston body has a first through hole, a first connecting portion, an accommodation space and a buffer space. The second piston body has a second through hole and a second connecting portion disposed inside the accommodation space. The fluid delivery pipe is accommodated in the first through hole and the second through hole, and movable between a first position and a second position. The sealing element encircles the fluid delivery pipe. When the fluid delivery pipe is at the first position, the sealing element is accommodated in the accommodation space. When the fluid delivery pipe is at the second position, a first part of the sealing element is accommodated in the accommodation space, and a second part of the sealing element is accommodated in the buffer space.

公开(公告)号：US20230321365A1

公开(公告)日：2023-10-12

申请号：US18013903

申请日：2021-06-28

Applicant: MICROBASE TECHNOLOGY CORP.

Inventor： CHI-JUI TANG ,  JO-LING WU

IPC: A61M11/00 ,  B05B11/10 ,  A61M15/00

CPC classification number: A61M11/007 ,  B05B11/1091 ,  B05B11/108 ,  A61M15/0073

Abstract: A nebulizer and a storage device are provided. The nebulizer includes a casing, an atomization module fixed to the casing, a rotating module rotatably assembled to the casing, a linking module assembled to the rotating module, and a locking module. The linking module is configured to be connected to a bottom of the container bottle, and the starting module is configured to drive the nebulizer by being pushed, thereby enabling liquid in the container bottle to be atomized toward an outside of the nebulizer through the atomization module in an atomization process. The locking module is configured to be connected to a bottom of the container bottle. When the nebulizer completes a predetermined number of times of the atomization process, the locking mechanism is moved toward the casing and is then limited to restrict an operation of the nebulizer. Accordingly, after the nebulizer completes the predetermined number of times of the atomization process, the locking module can restrict rotation of the rotating module for preventing the nebulizer from using the container bottle arranged therein.