公开(公告)号：US07848562B1

公开(公告)日：2010-12-07

申请号：US11235794

申请日：2005-09-26

Applicant: Steven Jacobson ,  Duc Huu Nguyen ,  William Ng ,  Zachary Joshua Gemmill ,  Usharani Bhimavarapu ,  Kevin Weaver

Inventor： Steven Jacobson ,  Duc Huu Nguyen ,  William Ng ,  Zachary Joshua Gemmill ,  Usharani Bhimavarapu ,  Kevin Weaver

IPC: G06K9/00

CPC classification number: G06T7/001 ,  G01R31/307 ,  G06T2207/10061 ,  G06T2207/30148

Abstract: The time required to perform a passive voltage contrast test of an area of interest of a layer of interest is substantially reduced by digitizing a passive voltage contrast image to form contrast data that represents the image, and comparing the contrast data to computer aided design (CAD) data that defines the semiconductor device.

Abstract translation: 通过将被动电压对比图像数字化以形成表示图像的对比度数据，并将对比度数据与计算机辅助设计（CAD）进行比较，实质上减少了感兴趣区域的感兴趣区域的被动电压对比度测试所需的时间 ）数据。

公开(公告)号：US08814880B2

公开(公告)日：2014-08-26

申请号：US11647921

申请日：2006-12-28

Applicant: Craig M. McAllister ,  Steven Jacobson

Inventor： Craig M. McAllister ,  Steven Jacobson

IPC: A61B17/58

CPC classification number: A61B17/86 ,  A61B17/8635 ,  A61B2017/8655 ,  A61B2090/031 ,  A61B2090/035 ,  A61B2090/3916 ,  A61B2090/3983

Abstract: A device for removable attachment to a bone of a living patient, useful as a mounting support for a trackable part of a computerized surgical navigation system and a method for attaching an object removably to a bone of a living patient. A shaft having a self drilling, self-tapping screw tip can be inserted transversely of the bone and securely screwed into the cortex. A screw drives a sharp-edged sleeve along the shaft to engage the near cortex. A stepping mechanism allows incremental angular movement of a portion of an adjustment mechanism and indicates when the sleeve is securely engaged by resisting further tightening.

Abstract translation: 一种用于可拆卸地附接到活的患者的骨头的装置，其可用作计算机化外科导航系统的可跟踪部分的安装支撑件，以及用于将物体可移除地附接到活体患者的骨骼的方法。 具有自钻自攻螺钉尖端的轴可以横向插入骨头并牢固地拧入皮层。 螺丝沿着轴驱动一个尖锐的袖子，以接近皮质。 步进机构允许调节机构的一部分的增量角运动，并且指示套筒何时通过抵抗进一步紧固而牢固地接合。

公开(公告)号：US07985226B2

公开(公告)日：2011-07-26

申请号：US11800137

申请日：2007-05-04

Applicant: Craig M. McAllister ,  Steven Jacobson

Inventor： Craig M. McAllister ,  Steven Jacobson

IPC: A61B17/58 ,  A61B17/60 ,  A61F2/00

CPC classification number: A61B17/155 ,  A61B17/1764

Abstract: A device and a method for establishing a position and orientation for a preliminary saw cut in a distal end of a femur to prepare the femur for installation of a prosthetic knee joint. A guide block defining a cutting plane is carried on an adjustably positioned locating arm that is supported on an alignment body that can be mounted on a femur either with or without an intramedullary rod in place in the distal end of the femur. Adjustment screws and horizontal slots in the alignment body provide for varus/valgus angular adjustment of the position of the alignment body. An adjustment guide block may have a saw guiding face defining a differently oriented cutting plane.

Abstract translation: 一种装置和方法，用于建立在股骨的远端中预备锯切的位置和方位，以准备用于安装假膝关节的股骨。 限定切割平面的引导块被承载在可调节定位的定位臂上，所述定位臂被支撑在对准主体上，该对准主体可以在有或没有髓内杆的情况下安装在股骨上，在股骨的远端中就位。 对准体内的调节螺钉和水平插槽可以对齐体的位置进行内翻/外翻角度调整。 调节引导块可以具有限定不同取向的切割平面的锯条引导面。

公开(公告)号：US20080161814A1

公开(公告)日：2008-07-03

申请号：US11647921

申请日：2006-12-28

Applicant: Craig M. McAllister ,  Steven Jacobson

Inventor： Craig M. McAllister ,  Steven Jacobson

IPC: A61B17/00 ,  A61B17/56 ,  A61B17/58

CPC classification number: A61B17/86 ,  A61B17/8635 ,  A61B2017/8655 ,  A61B2090/031 ,  A61B2090/035 ,  A61B2090/3916 ,  A61B2090/3983

Abstract: A device for removable attachment to a bone of a living patient, useful as a mounting support for a trackable part of a computerized surgical navigation system and a method for attaching an object removably to a bone of a living patient. A shaft having a self drilling, self-tapping screw tip can be inserted transversely of the bone and securely screwed into the cortex. A screw drives a sharp-edged sleeve along the shaft to engage the near cortex. A stepping mechanism allows incremental angular movement of a portion of an adjustment mechanism and indicates when the sleeve is securely engaged by resisting further tightening.

Abstract translation: 一种用于可拆卸地附接到活的患者的骨头的装置，其可用作计算机化外科导航系统的可跟踪部分的安装支撑件，以及用于将物体可移除地附接到活体患者的骨骼的方法。 具有自钻自攻螺钉尖端的轴可以横向插入骨头并牢固地拧入皮层。 螺丝沿着轴驱动一个尖锐的袖子，以接近皮质。 步进机构允许调节机构的一部分的增量角运动，并且指示套筒何时通过抵抗进一步紧固而牢固地接合。

公开(公告)号：US08529573B2

公开(公告)日：2013-09-10

申请号：US13134824

申请日：2011-06-16

Applicant: Craig M. McAllister ,  Steven Jacobson

Inventor： Craig M. McAllister ,  Steven Jacobson

IPC: A61B17/58 ,  A61B17/60 ,  A61F2/00

CPC classification number: A61B17/155 ,  A61B17/1764

Abstract: A device and a method for establishing a position and orientation for a preliminary saw cut in a distal end of a femur to prepare the femur for installation of a prosthetic knee joint. A guide block defining a cutting plane is carried on an adjustably positioned locating arm that is supported on an alignment body that can be mounted on a femur either with or without an intramedullary rod in place in the distal end of the femur. Adjustment screws and horizontal slots in the alignment body provide for varus/valgus angular adjustment of the position of the alignment body. An adjustment guide block may have a saw guiding face defining a differently oriented cutting plane.

Abstract translation: 一种装置和方法，用于建立在股骨的远端中预备锯切的位置和方位，以准备用于安装假膝关节的股骨。 限定切割平面的引导块被承载在可调节定位的定位臂上，所述定位臂被支撑在对准主体上，该对准主体可以在有或没有髓内杆的情况下安装在股骨上，在股骨的远端中就位。 对准体内的调节螺钉和水平插槽可以对齐体的位置进行内翻/外翻角度调整。 调节引导块可以具有限定不同取向的切割平面的锯条引导面。

公开(公告)号：US20110251618A1

公开(公告)日：2011-10-13

申请号：US13134824

申请日：2011-06-16

Applicant: Craig M. McAllister ,  Steven Jacobson

Inventor： Craig M. McAllister ,  Steven Jacobson

IPC: A61B17/56

CPC classification number: A61B17/155 ,  A61B17/1764

Abstract: A device and a method for establishing a position and orientation for a preliminary saw cut in a distal end of a femur to prepare the femur for installation of a prosthetic knee joint. A guide block defining a cutting plane is carried on an adjustably positioned locating arm that is supported on an alignment body that can be mounted on a femur either with or without an intramedullary rod in place in the distal end of the femur. Adjustment screws and horizontal slots in the alignment body provide for varus/valgus angular adjustment of the position of the alignment body. An adjustment guide block may have a saw guiding face defining a differently oriented cutting plane.

公开(公告)号：US07748984B2

公开(公告)日：2010-07-06

申请号：US11351965

申请日：2006-02-10

Applicant: Craig M. McAllister ,  Steven Jacobson

Inventor： Craig M. McAllister ,  Steven Jacobson

IPC: G09B23/28

CPC classification number: G09B23/30 ,  G09B23/32

Abstract: A tray and a clamp mounted adjustably on the tray and supporting a leg or other limb or simulated limb including an articulated animal joint or a joint from a cadaver, for use in instruction of and practice by surgeons in joint replacement or other orthopedic surgery. A bone mounting device for fastening a joint to an artificial bone includes an expandable engagement member that fits within a cavity formed within a bone to hold the bone securely so that a surgical procedure can be performed on the joint.

Abstract translation: 托盘和夹具可调节地安装在托盘上并且支撑腿或其他肢体或模拟肢体，其包括铰接的动物关节或来自尸体的关节，用于外科医生在关节置换术或其他整形外科手术中的指导和练习。 用于将接头紧固到人造骨的骨安装装置包括可扩张接合构件，该可扩张接合构件装配在形成在骨内的空腔内，以牢固地保持骨骼，使得可以在关节上执行外科手术。

公开(公告)号：US20070178532A1

公开(公告)日：2007-08-02

申请号：US10551126

申请日：2004-03-24

Applicant: Steven Jacobson ,  Utano Takeuchi ,  Yoshihisa Yamano

Inventor： Steven Jacobson ,  Utano Takeuchi ,  Yoshihisa Yamano

IPC: G01N33/567 ,  C07H21/04 ,  C12P21/06 ,  C12N5/08 ,  C07K14/435

CPC classification number: G01N33/56977 ,  G01N33/505 ,  G01N2800/52

Abstract: Methods of quantifying and/or characterizing antigen-specific T cell populations, identifying T cell antigens and epitopes, and preparing targeted pharmaceutical compositions by (i) introducing a peptide into an antigen-presenting cell (APC) expressing a fusion protein comprising a major histocompatibility complex portion and a reporter peptide portion such that a complex forms between the fusion protein and the peptide and the peptide is displayed by the APC and (ii) contacting the APC with a population of cells, such that T cells in the population of cells that react with the peptide detectably internalize the complex; novel APCs useful in such methods; and related therapeutic and diagnostic methods.

Abstract translation: 定量和/或表征抗原特异性T细胞群体，鉴定T细胞抗原和表位的方法，以及通过（i）将肽引入表达融合蛋白的抗原呈递细胞（APC）并制备靶向药物组合物，所述抗原呈递细胞（APC）包含主要组织相容性 复合部分和报道肽部分，使得融合蛋白和肽之间形成复合物，肽显示APC，和（ii）使APC与细胞群接触，使得细胞群体中的T细胞 与肽反应可检测内在化复合物; 这种方法有用的新型APC; 以及相关的治疗和诊断方法。

公开(公告)号：US06392213B1

公开(公告)日：2002-05-21

申请号：US09690000

申请日：2000-10-12

Applicant: Richard T. Martorana ,  Jamie Anderson ,  Simon Mark Spearing ,  Seth Kessler ,  Brent Appleby ,  Edward Bergmann ,  Sean George ,  Steven Jacobson ,  Donald Fyler ,  Mark Drela ,  Gregory Kirkos ,  William McFarland, Jr.

Inventor： Richard T. Martorana ,  Jamie Anderson ,  Simon Mark Spearing ,  Seth Kessler ,  Brent Appleby ,  Edward Bergmann ,  Sean George ,  Steven Jacobson ,  Donald Fyler ,  Mark Drela ,  Gregory Kirkos ,  William McFarland, Jr.

IPC: B64C351

CPC classification number: F42B15/105 ,  B64C39/024 ,  B64C2201/042 ,  B64C2201/084 ,  B64C2201/102 ,  B64C2201/127 ,  B64C2201/146 ,  B64C2201/165 ,  B64C2201/185 ,  B64C2201/201

Abstract: A flyer assembly is adapted for launching with, transit in, and deployment from an artillery shell having a central void region extending along a ballistic shell axis. The flyer assembly includes a jettisonable shroud and a flyer. The shroud extends along a shroud axis, and is positionable within the central void region with the shroud axis substantially parallel to the shell axis. The flyer is adapted to withstand a launch acceleration force along a flyer axis when in a first state, and to effect aerodynamic flight when in a second state. When in the first state, the flyer is positionable within the shroud with the flyer axis parallel to the shroud axis and the shell axis. The flyer includes a body member disposed about the flyer axis, and a foldable wing assembly mounted to the body member. The wing assembly is configurable in a folded state characterized by a plurality of nested wing segments when the flyer is in the first state. The wing assembly is configurable in an unfolded state characterized by a substantially uninterrupted aerodynamic surface when the flyer is in the second state. The flyer assembly is adapted to be launched from a ballistic delivery system such as an artillery cannon, and can thus reach a target quickly, without expending system energy stored within the flyer. During launch, the flyer is coupled to the shroud so as to maintain a portion of the flyer in tension during an acceleration of the flyer along the flyer axis resulting from the launch. The flyer assembly is adapted to withstand the high g-load and high temperature environments of a cannon launch, and can tolerate a set-back g load of about 16,000 g.

Abstract translation: 飞行器组件适用于从具有沿弹道壳轴线延伸的中心空隙区域的炮弹发射，转移和展开。 传单组件包括可喷射的护罩和传单​​。 护罩沿护罩轴线延伸，并且可定位在中心空隙区域内，护罩轴线基本上平行于外壳轴线。 飞行器适于在处于第一状态时承受沿飞行器轴的发射加速力，并且在处于第二状态时实现空气动力学飞行。 当处于第一状态时，传单可定位在护罩内，飞翼轴线平行于护罩轴线和外壳轴线。 传单包括围绕飞翼轴设置的主体部件和安装到主体部件的可折叠翼组件。 翼组件可配置成折叠状态，其特征在于当传单处于第一状态时由多个嵌套翼片段组成。 机翼组件可配置为展开状态，其特征在于当传单处于第二状态时基本上不间断的空气动力学表面。 飞行器组件适于从诸如炮兵炮的弹道传送系统发射，并且因此可以快速到达目标，而不会消耗存储在飞行物内的系统能量。 在发射期间，传单联接到护罩上，以便在飞行物沿着由发射引起的飞翼轴的加速期间，使传单的一部分保持张紧。 飞行器组件适于承受大炮发射的高负载和高温环境，并且可以容忍约16,000g的安装载荷。

公开(公告)号：US5644486A

公开(公告)日：1997-07-01

申请号：US327246

申请日：1994-10-24

Applicant: Sung S. Chang ,  James L. Harman ,  Gary Steven Jacobson ,  Wesley A. Kirschner ,  Micheal J. Ramadei ,  Eric L. Zuidema

Inventor： Sung S. Chang ,  James L. Harman ,  Gary Steven Jacobson ,  Wesley A. Kirschner ,  Micheal J. Ramadei ,  Eric L. Zuidema

IPC: G05B19/416 ,  G06F19/00

CPC classification number: G05B19/416 ,  G05B2219/34216 ,  G05B2219/34418 ,  G05B2219/36056 ,  G05B2219/36395

Abstract: An apparatus for controlling a mechanical system in response to messages from a host computer system. The apparatus includes a conventional communications link for communicating messages from the host computer system to a motion control processor and interface and driver circuits for converting digital signals generated by the motion control processor in response to messages from the host computer system into control signals having appropriate waveforms and timing for controlling a particular mechanical system. The motion control processor is programmed to perform a number of tasks in accordance with a schedule downloaded from the host computer system. The host computer system downloads profiles which consist of series of segments consisting of data structures which define elements in the mechanical system to be controlled, identify functions to be performed and include necessary data. Tasks performed by the motion control processor include a communications interface task for handling messages from the host data system, a profile handler task for executing profiles, a motion control task for controlling motors in the mechanical system, and a read sensors task for reading sensor in the mechanical system. Other conventional, non-critical tasks may be performed by the motion control processor on a less frequently scheduled basis or in a background mode of operation. New profiles, schedules, and tick period duration may be down loaded from the host computer system dynamically, during operation of the mechanical system to provide highly flexible, adaptive control of the mechanical system.

Abstract translation: 一种用于响应于来自主计算机系统的消息来控制机械系统的装置。 该装置包括用于将来自主计算机系统的消息传送到运动控制处理器的传统通信链路，以及用于将由运动控制处理器生成的数字信号响应于来自主计算机系统的消息转换成具有适当波形的控制信号的接口和驱动器电路 以及用于控制特定机械系统的时序。 运动控制处理器被编程为根据从主计算机系统下载的调度来执行多个任务。 主计算机系统下载由包括在要控制的机械系统中定义要素的数据结构组成的一系列段的轮廓，识别待执行的功能并且包括必要的数据。 由运动控制处理器执行的任务包括用于处理来自主机数据系统的消息的通信接口任务，用于执行简档的简档处理程序任务，用于控制机械系统中的电动机的运动控制任务以及用于读取传感器的读取传感器任务 机械系统。 运动控制处理器可以在较不频繁调度的基础上或在背景操作模式中执行其他常规的非关键任务。 在机械系统的运行期间，可以从主机系统动态地下载新的配置文件，日程表和打勾周期持续时间，以提供对机械系统的高度灵活的自适应控制。