公开(公告)号：US20050147841A1

公开(公告)日：2005-07-07

申请号：US10508914

申请日：2003-03-24

Applicant: Avto Tavkhelidze ,  Stuart Harbron

Inventor： Avto Tavkhelidze ,  Stuart Harbron

IPC: B32B3/30 ,  C23F3/00 ,  C30B29/02 ,  C30B33/00

CPC classification number: C30B29/02 ,  C30B33/00 ,  Y10T29/49117 ,  Y10T428/12389 ,  Y10T428/12993

Abstract: The influence of surface geometry on metal properties is studied within the limit of the quantum theory of free electrons. It is shown that a metal surface can be modified with patterned indents to increase the Fermi energy level inside the metal, leading to decrease in electron work function. This effect would exist in any quantum system comprising fermions inside a potential energy box. Also disclosed is a method for making nanostructured surfaces having perpendicular features with sharp edges.

Abstract translation: 在自由电子量子理论的极限范围内研究了表面几何对金属性能的影响。 显示出金属表面可以用图案化的凹痕改性以增加金属内的费米能级，导致电子功函数的降低。 这种效应将存在于潜在能量盒内的包含费米子的任何量子系统中。 还公开了一种制造具有锋利边缘的垂直特征的纳米结构表面的方法。

公开(公告)号：US06423492B1

公开(公告)日：2002-07-23

申请号：US09403105

申请日：1999-10-14

Applicant: Stuart Harbron

Inventor： Stuart Harbron

IPC: C12Q168

CPC classification number: C12Q1/6846 ,  C12Q2537/143 ,  C12Q2525/191

Abstract: A method is disclosed for detecting single-stranded target nucleic acid (2) which comprises the steps of forming a hybrid between said target nucleic acid and a nucleic acid probe (4), said nucleic acid probe labelled with an enzyme reagent (6) which hydrolyses single-stranded nucleic acid but is substantially without effect on double-stranded nucleic acid, said hybrid formed under conditions of pH which are outside the activity range of said enzyme reagent, adjusting said pH to a value within the activity range of said enzyme reagent allowing said enzyme reagent substantially to hydrolyse any single-stranded nucleic acid present, and detecting said hybrid.

Abstract translation: 公开了用于检测单链靶核酸（2）的方法，其包括在所述靶核酸和核酸探针（4）之间形成杂交体的步骤，所述核酸探针用酶试剂（6）标记，所述酶试剂 水解单链核酸，但对双链核酸基本上没有影响，所述杂化物在pH值在所述酶试剂的活性范围之外的条件下形成，将所述pH调节至所述酶试剂活性范围内的值 允许所述酶试剂基本上水解存在的任何单链核酸，并检测所述杂交体。

公开(公告)号：US07935954B2

公开(公告)日：2011-05-03

申请号：US11598918

申请日：2006-11-13

Applicant: Avto Tavkhelidze ,  Jonathan Sidney Edelson ,  Isaiah Watas Cox ,  Stuart Harbron

Inventor： Avto Tavkhelidze ,  Jonathan Sidney Edelson ,  Isaiah Watas Cox ,  Stuart Harbron

IPC: H01L29/06

CPC classification number: B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  G03F7/0002 ,  H01J1/30 ,  H01L21/4867 ,  H01L29/127 ,  H01L31/0352 ,  Y10S977/755 ,  Y10S977/781 ,  Y10S977/782 ,  Y10S977/81

Abstract: A method is disclosed for the induction of a suitable band gap and electron emissive properties into a substance, in which the substrate is provided with a surface structure corresponding to the interference of electron waves. Lithographic or similar techniques are used, either directly onto a metal mounted on the substrate, or onto a mold which then is used to impress the metal. In a preferred embodiment, a trench or series of nano-sized trenches are formed in the metal.

Abstract translation: 公开了一种用于将合适的带隙和电子发射性质诱导到物质中的方法，其中衬底具有对应于电子波干涉的表面结构。 使用平版印刷或类似技术，直接用于安装在基板上的金属上，或者用于模具，然后用于印刷金属。 在优选实施例中，在金属中形成沟槽或一系列纳米尺寸的沟槽。

公开(公告)号：US07074498B2

公开(公告)日：2006-07-11

申请号：US10508914

申请日：2003-03-24

Applicant: Avto Tavkhelidze ,  Stuart Harbron

Inventor： Avto Tavkhelidze ,  Stuart Harbron

IPC: C23F4/00 ,  H01R3/00 ,  H01L21/00

CPC classification number: C30B29/02 ,  C30B33/00 ,  Y10T29/49117 ,  Y10T428/12389 ,  Y10T428/12993

Abstract: The influence of surface geometry on metal properties is studied within the limit of the quantum theory of free electrons. It is shown that a metal surface can be modified with patterned indents to increase the Fermi energy level inside the metal, leading to decrease in electron work function. This effect would exist in any quantum system comprising fermions inside a potential energy box. Also disclosed is a method for making nanostructured surfaces having perpendicular features with sharp edges.

Abstract translation: 在自由电子量子理论的极限范围内研究了表面几何对金属性能的影响。 显示出金属表面可以用图案化的凹痕改性以增加金属内的费米能级，导致电子功函数的降低。 这种效应将存在于潜在能量盒内的包含费米子的任何量子系统中。 还公开了一种制造具有锋利边缘的垂直特征的纳米结构表面的方法。

公开(公告)号：US06680214B1

公开(公告)日：2004-01-20

申请号：US09634615

申请日：2000-08-05

Applicant: Avto Tavkhelidze ,  Jonathan Sidney Edelson ,  Isaiah Watas Cox ,  Stuart Harbron

Inventor： Avto Tavkhelidze ,  Jonathan Sidney Edelson ,  Isaiah Watas Cox ,  Stuart Harbron

IPC: G25F302

CPC classification number: B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  G03F7/0002 ,  H01J1/30 ,  H01L21/4867 ,  H01L29/127 ,  H01L31/0352 ,  Y10S977/755 ,  Y10S977/781 ,  Y10S977/782 ,  Y10S977/81

Abstract: A method is disclosed for the induction of a suitable band gap and electron emissive properties into a substance, in which the substrate is provided with a surface structure corresponding to the interference of electron waves. Lithographic or similar techniques are used, either directly onto a metal mounted on the substrate, or onto a mold which then is used to impress the metal. In a preferred embodiment, a trench or series of nano-sized trenches are formed in the metal.

Abstract translation: 公开了一种用于将合适的带隙和电子发射性质诱导到物质中的方法，其中衬底具有对应于电子波干涉的表面结构。 使用平版印刷或类似技术，直接用于安装在基板上的金属上，或者用于模具，然后用于印刷金属。 在优选实施例中，在金属中形成沟槽或一系列纳米尺寸的沟槽。

公开(公告)号：US06362328B1

公开(公告)日：2002-03-26

申请号：US09297257

申请日：1999-09-20

Applicant: Mark Fisher ,  Christopher John Taylorson ,  Stuart Harbron

Inventor： Mark Fisher ,  Christopher John Taylorson ,  Stuart Harbron

IPC: C07H2104

CPC classification number: G01N33/581 ,  G01N33/535

Abstract: Probes comprise S1 and P1 nuclease (as an enzyme label) linked to a specific binding member such as a nucleotide sequence or an antibody. Such probes are useful for sandwich assays. As compared with known probes using alkaline phosphatase as a label, advantages include relative insensitivity to phosphate and elevated temperature and reduced risk of nonspecific binding.

Abstract translation: 探针包含与特异性结合成员如核苷酸序列或抗体连接的S1和P1核酸酶（作为酶标记）。 这种探针可用于夹心测定。 与使用碱性磷酸酶作为标记的已知探针相比，优点包括对磷酸盐的相对不敏感和升高的温度以及降低非特异性结合的风险。