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    APPARATUS AND METHOD FOR PROVIDING SEARCH PATTERN OF USER IN MOBILE TERMINAL
    11.
    发明申请
    APPARATUS AND METHOD FOR PROVIDING SEARCH PATTERN OF USER IN MOBILE TERMINAL 有权
    提供移动终端用户搜索模式的装置和方法

    公开(公告)号：US20120310981A1

    公开(公告)日：2012-12-06

    申请号：US13298674

    申请日：2011-11-17

    Applicant: Sung-Chan LEE ,  Jong-Min LEE

    Inventor： Sung-Chan LEE ,  Jong-Min LEE

    IPC: G06F17/30

    CPC classification number: G06F17/30964 ,  G06Q30/0256 ,  G06Q30/0261

    Abstract: In a mobile terminal, user search information used in a Location Based Service (LBS) application is stored. A user search pattern is determined from the user search information. User search pattern information corresponding to search condition data is extracted and displayed when the search condition data are input in a search pattern mode of the LBS application.

    Abstract translation: 在移动终端中，存储在基于位置的服务（LBS）应用中使用的用户搜索信息。 从用户搜索信息确定用户搜索模式。 当搜索条件数据以LBS应用的搜索模式模式输入时，提取并显示与搜索条件数据相对应的用户搜索模式信息。

    Reverse-turn mimetics and method relating thereto
    12.
    发明授权
    Reverse-turn mimetics and method relating thereto 有权
    反转模拟物及其相关方法

    公开(公告)号：US08106049B2

    公开(公告)日：2012-01-31

    申请号：US12553858

    申请日：2009-09-03

    Applicant: Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen

    Inventor： Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen

    IPC: C07D487/04 ,  A61K31/53

    CPC classification number: C07D487/04

    Abstract: Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility as diagnostic and therapeutic agents for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis. In one embodiment, these reverse-term mimetics have a general structure of formula (VI): wherein Ra, Rb, Rc, X1, X2 and X3 are defined as provided herein.

    Abstract translation: 公开了模拟生物活性肽和蛋白质的反转转区的二级结构的构象约束化合物。 这种反转模拟结构具有用作抑制或治疗由Wnt信号传导途径调节的疾病，如癌症，特别是结肠直肠癌，与血管成形术，多囊肾病，异常血管生成疾病，类风湿性关节炎疾病相关的再狭窄的诊断和治疗剂的效用， 结节性硬化综合征，阿尔茨海默氏病，过度毛发生长或丧失或溃疡性结肠炎。 在一个实施方案中，这些反相模拟物具有式（VI）的通式结构：其中R a，R b，R c，X 1，X 2和X 3如本文所提供。

    REVERSE-TURN MIMETICS AND METHOD RELATING THERETO
    13.
    发明申请
    REVERSE-TURN MIMETICS AND METHOD RELATING THERETO 有权
    反向转换和相关的方法

    公开(公告)号：US20110294797A1

    公开(公告)日：2011-12-01

    申请号：US13194428

    申请日：2011-07-29

    Applicant: Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen

    Inventor： Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen

    IPC: A61K31/538 ,  A61K31/53 ,  A61P17/14 ,  A61P35/00 ,  A61P19/02 ,  A61P25/28 ,  C07D487/04 ,  A61K31/5377

    CPC classification number: C07D487/04

    Abstract: Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members. The invention also relates to the use of such compounds for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis.

    Abstract translation: 公开了模拟生物活性肽和蛋白质的反转转区的二级结构的构象约束化合物。 这种反转模拟结构在广泛的领域中具有实用性，包括用作诊断和治疗剂。 还公开了含有本发明的反转模拟结构的文库以及筛选该文库以鉴定生物活性成员的方法。 本发明还涉及这种化合物用于抑制或治疗由Wnt信号传导途径调节的疾病，例如癌症，特别是结肠直肠癌，与血管成形术，多囊肾病，异常血管生成疾病，类风湿性关节炎疾病，结节性硬化综合征相关的再狭窄 ，阿尔茨海默氏病，过度毛发生长或损失，或溃疡性结肠炎。

    Reverse-turn mimetics and method relating thereto
    14.
    发明授权
    Reverse-turn mimetics and method relating thereto 有权
    反转模拟物及其相关方法

    公开(公告)号：US07671054B1

    公开(公告)日：2010-03-02

    申请号：US11974941

    申请日：2007-10-15

    Applicant: Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen ,  Soo Jin Lee

    Inventor： Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen ,  Soo Jin Lee

    IPC: C07D487/04 ,  A61K31/53 ,  A61P19/02 ,  A61P35/00

    CPC classification number: C07D487/04 ,  A61K31/53

    Abstract: Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins as well as their prodrugs are disclosed. Such reverse-turn mimetic structures and prodrugs have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members. The invention also relates to the use of such compounds and prodrugs for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis.

    Abstract translation: 公开了模拟生物活性肽和蛋白质的逆转转区域的二级结构及其前药的构象约束化合物。 这种反转模拟结构和前药在广泛的领域中具有实用性，包括用作诊断和治疗剂。 还公开了包含本发明的反转模拟结构的文库以及用于筛选其的方法以鉴定生物活性成员。 本发明还涉及这些化合物和前药用于抑制或治疗由Wnt信号传导途径调节的疾病如癌症，特别是结肠直肠癌，与血管成形术相关的再狭窄，多囊肾病，异常血管生成疾病，类风湿性关节炎疾病，结节性 硬化综合征，阿尔茨海默氏病，过度头发生长或损失，或溃疡性结肠炎。

    Attachment coupling device for heavy machinery
    17.
    发明授权
    Attachment coupling device for heavy machinery 失效
    重型机械附件联轴器

    公开(公告)号：US07014385B2

    公开(公告)日：2006-03-21

    申请号：US10490446

    申请日：2002-09-25

    Applicant: Jong Hyuk Lim ,  Sung Chan Lee

    Inventor： Jong Hyuk Lim ,  Sung Chan Lee

    IPC: F16D1/00

    CPC classification number: E02F3/3618 ,  E02F3/3663 ,  Y10S37/903 ,  Y10T403/59 ,  Y10T403/591 ,  Y10T403/593 ,  Y10T403/595 ,  Y10T403/598

    Abstract: An attachment coupling device is designed to releasably connect a variety of attachments to an arm and a push link of heavy machinery such as hydraulic excavators. The attachment coupling device comprises a pair of mounting brackets fixedly secured to the attachment, each bracket having first and second hooks spaced apart with each other. Another major element of the coupling device is a coupler which includes, a fixed plate affixed to the arm and the push link, a pair of fixed coupling pins each protruding outwardly from the fixed plate for engagement with the first hook of each of the mounting brackets, a pair of movable coupling pins for movement between a retracted release position and an extended coupling position wherein the respective one of the movable pins comes into engagement with the second hook of each of the mounting brackets, and an actuator for causing movement of the movable coupling pins.

    Abstract translation: 连接联接装置被设计成将各种附件可释放地连接到诸如液压挖掘机的重型机械的臂和推连杆上。 附接联接装置包括固定在附件上的一对安装支架，每个支架具有彼此间隔开的第一和第二钩。 联接装置的另一个主要元件是联接器，其包括固定到臂和推动连杆的固定板，一对固定联接销，每个固定联接销从固定板向外突出，用于与每个安装支架的第一钩接合 ，一对可移动联接销，用于在缩回释放位置和延伸联接位置之间移动，其中相应的一个可动销与每个安装支架的第二钩接合;以及致动器，用于使可动 连接销。

    Reverse-turn mimetics and method relating thereto
    20.
    发明授权
    Reverse-turn mimetics and method relating thereto 有权
    反转模拟物及其相关方法

    公开(公告)号：US08318738B2

    公开(公告)日：2012-11-27

    申请号：US13194428

    申请日：2011-07-29

    Applicant: Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen

    Inventor： Sung Hwan Moon ,  Jae Uk Chung ,  Sung Chan Lee ,  Masakatsu Eguchi ,  Michael Kahn ,  Kwang Won Jeong ,  Cu Nguyen

    IPC: C07D487/04 ,  A61K31/53

    CPC classification number: C07D487/04

    Abstract: Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members. The invention also relates to the use of such compounds for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis.

    Abstract translation: 公开了模拟生物活性肽和蛋白质的反转转区的二级结构的构象约束化合物。 这种反转模拟结构在广泛的领域中具有实用性，包括用作诊断和治疗剂。 还公开了包含本发明的反转模拟结构的文库以及用于筛选其的方法以鉴定生物活性成员。 本发明还涉及这种化合物用于抑制或治疗由Wnt信号传导途径调节的疾病，例如癌症，特别是结肠直肠癌，与血管成形术，多囊肾病，异常血管生成疾病，类风湿性关节炎疾病，结节性硬化综合征相关的再狭窄 ，阿尔茨海默氏病，过度毛发生长或损失，或溃疡性结肠炎。

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