公开(公告)号：US09834766B2

公开(公告)日：2017-12-05

申请号：US14342048

申请日：2012-09-04

Applicant: Wayne Volkmuth ,  Yann Chong Tan

Inventor： Wayne Volkmuth ,  Yann Chong Tan

IPC: G01N33/48 ,  C12N15/10 ,  C12Q1/68 ,  G06F19/22 ,  G06F19/18 ,  G06G7/58

CPC classification number: C12N15/1089 ,  C12N15/1065 ,  C12Q1/6869 ,  C12Q1/6876 ,  C12Q2600/166 ,  G06F19/18 ,  G06F19/22 ,  C12Q2525/15 ,  C12Q2535/122 ,  C12Q2537/165

Abstract: The present disclosure provides methods for optimizing barcode design for multiplex DNA sequencing. Also disclosed are DNA barcodes optimized for use with particular sequencing technologies.

公开(公告)号：US20090265815A1

公开(公告)日：2009-10-22

申请号：US10645822

申请日：2003-08-22

Applicant: Nickolai Alexandrov ,  Nestor Apuya ,  Vyacheslav Brover ,  Xianfeng Chen ,  Jean-Baptiste Dumas ,  Yiwen Fang ,  Kenneth Feldmann ,  Peter Mascia ,  Jack Okamuro ,  Roger Pennell ,  Richard Schneegerger ,  Gopalakrishnan Subramanian ,  Maxim Troukhan ,  Liansheng Zheng ,  Edward Kiegle ,  Diane Jofuku Okamuro ,  William J. Kimmerly ,  Shing Kwok ,  Tatiana Tatarinova ,  Wayne Volkmuth

Inventor： Nickolai Alexandrov ,  Nestor Apuya ,  Vyacheslav Brover ,  Xianfeng Chen ,  Jean-Baptiste Dumas ,  Yiwen Fang ,  Kenneth Feldmann ,  Peter Mascia ,  Jack Okamuro ,  Roger Pennell ,  Richard Schneegerger ,  Gopalakrishnan Subramanian ,  Maxim Troukhan ,  Liansheng Zheng ,  Edward Kiegle ,  Diane Jofuku Okamuro ,  William J. Kimmerly ,  Shing Kwok ,  Tatiana Tatarinova ,  Wayne Volkmuth

IPC: A01H5/00 ,  C12N15/11 ,  C12N15/00 ,  C12N5/04 ,  C07K14/00 ,  C07K16/18 ,  C12N15/87 ,  C12Q1/68

CPC classification number: C12N15/8271 ,  C07K14/415 ,  C07K16/16 ,  C12N15/8273 ,  C12Q1/6876 ,  C12Q2600/158

Abstract: The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3′ termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait. One of ordinary skill in the art, having this data, can obtain cloned DNA fragments, synthetic DNA fragments or polypeptides constituting desired sequences by recombinant methodology known in the art or described herein

Abstract translation: 本发明提供构成植物基因组片段的DNA分子，以及由此编码的多肽。 DNA分子可用于指定细胞中的基因产物，作为启动子或蛋白质编码序列或作为UTR或作为3'终止序列，并且还可用于控制染色体中基因的行为， 在控制基因的表达或用于遗传作图，识别或分离相同或相关的DNA片段，或特定个体生物体的鉴定或用于具有共同性状的一组生物体的聚类的工具。 具有该数据的本领域普通技术人员可以通过本领域已知的或本文所述的重组方法获得克隆的DNA片段，合成的DNA片段或构成所需序列的多肽

公开(公告)号：US06602667B1

公开(公告)日：2003-08-05

申请号：US09855323

申请日：2001-05-14

Applicant: Michael G. Walker ,  Wayne Volkmuth ,  Tod M. Klingler

Inventor： Michael G. Walker ,  Wayne Volkmuth ,  Tod M. Klingler

IPC: C12Q168

CPC classification number: C07K14/47 ,  A61K38/00

Abstract: The invention provides compositions and novel polynucleotides and proteins that co-express with known marker genes for inflammatory disorders. The invention also provides expression vectors, host cells, proteins encoded by the polynucleotides and antibodies which specifically bind the proteins. The invention also provides methods for the diagnosis, prognosis, evaluation of therapies and treatment of inflammatory disorders.

公开(公告)号：US06277574B1

公开(公告)日：2001-08-21

申请号：US09289349

申请日：1999-04-09

Applicant: Michael G. Walker ,  Wayne Volkmuth ,  Tod M. Klingler ,  Yalda Azimzai ,  Henry Yue

Inventor： Michael G. Walker ,  Wayne Volkmuth ,  Tod M. Klingler ,  Yalda Azimzai ,  Henry Yue

IPC: C12Q168

CPC classification number: C07K14/47 ,  A61K38/00 ,  A61K48/00 ,  A61K2039/505

Abstract: The invention provides novel kidney disease-associated genes and polypeptides encoded by those genes. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for diagnosing, treating or preventing diseases of the kidney.

Abstract translation: 本发明提供了由这些基因编码的新型肾病相关基因和多肽。 本发明还提供表达载体，宿主细胞和抗体。 本发明还提供了用于诊断，治疗或预防肾脏疾病的方法。