Remote node for wavelength-division-multiplexed passive optical network
    13.
    发明授权
    Remote node for wavelength-division-multiplexed passive optical network 失效
    波分复用无源光网络的远程节点

    公开(公告)号:US08639119B2

    公开(公告)日:2014-01-28

    申请号:US12935805

    申请日:2009-03-31

    IPC分类号: H04J14/00 H04J14/02

    摘要: A remote node for a wavelength-division-multiplexed passive optical network (WDM PON). The remote node comprises means for receiving uplink optical signals from one or more optical network units of the WDM PON; a broadband reflector for reflecting a self-seeding portion of the respective uplink optical signals to the respective uplink light sources; and wherein the reflector comprises a gain medium and is configured for receiving a pump optical signal from a central office of the WDM PON for amplifying the self seeding portion of the respective uplink optical signal.

    摘要翻译: 用于波分复用无源光网络(WDM PON)的远程节点。 远程节点包括用于从WDM PON的一个或多个光网络单元接收上行光信号的装置; 宽带反射器,用于将各个上行链路光信号的自播种部分反射到相应的上行链路光源; 并且其中所述反射器包括增益介质,并且被配置为从所述WDM PON的中心局接收泵浦光信号,用于放大所述相应上行链路光信号的自播种部分。

    COPY NUMBER ALTERATIONS THAT PREDICT METASTATIC CAPABILITY OF HUMAN BREAST CANCER
    14.
    发明申请
    COPY NUMBER ALTERATIONS THAT PREDICT METASTATIC CAPABILITY OF HUMAN BREAST CANCER 审中-公开
    预测人乳腺癌的分类能力的复制编号

    公开(公告)号:US20090155805A1

    公开(公告)日:2009-06-18

    申请号:US12335162

    申请日:2008-12-15

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/6827

    摘要: Disclosed in this specification is a method of defining chromosome regions of prognostic value by summarizing the significance of all SNPs (single nucleotide polymorphism) in a predetermined section of a chromosome to define chromosome regions of prognostic value. Based on the SNPs in specified genes, a more accurate prognosis for breast cancer may be provided.

    摘要翻译: 在本说明书中公开的是通过总结染色体预定部分中所有SNP(单核苷酸多态性)的意义来定义预后价值的染色体区域来定义预后价值的染色体区域的方法。 基于特定基因的SNP,可以提供更准确的乳腺癌预后。

    Breast cancer prognostic portfolio
    15.
    发明授权
    Breast cancer prognostic portfolio 失效
    乳腺癌预后组合

    公开(公告)号:US07473526B2

    公开(公告)日:2009-01-06

    申请号:US10393590

    申请日:2003-03-21

    申请人: Yixin Wang

    发明人: Yixin Wang

    IPC分类号: C12Q1/68 C07H21/04

    摘要: A method of prognosticating metastasis in a breast cancer patient involves identifying differential modulation of each gene (relative to the expression of the same genes in a normal population) in a combination of genes as well as kits for employing the method.

    摘要翻译: 在乳腺癌患者中预测转移的方法包括鉴定基因组合中每个基因的差异调节(相对于正常群体中相同基因的表达)以及用于该方法的试剂盒。

    Cancer diagnostic panel
    16.
    发明授权
    Cancer diagnostic panel 失效
    癌症诊断面板

    公开(公告)号:US07348142B2

    公开(公告)日:2008-03-25

    申请号:US10393567

    申请日:2003-03-21

    申请人: Yixin Wang

    发明人: Yixin Wang

    IPC分类号: C12Q1/68 C07H21/02 C07H21/04

    摘要: A method of diagnosing cancer by identifying differential modulation of each gene (relative to the expression of the same genes in a normal population) in a combination of genes selected from two groups of genes.Gene expression portfolios and kits for employing the method are further aspects of the invention.

    摘要翻译: 通过鉴定选自两组基因的基因的组合,通过鉴定每个基因的差异调节(相对于正常群体中相同基因的表达)来诊断癌症的方法。 用于采用该方法的基因表达组合和试剂盒是本发明的另外的方面。

    Methods and reagents for the detection of melanoma
    17.
    发明申请
    Methods and reagents for the detection of melanoma 审中-公开
    用于检测黑色素瘤的方法和试剂

    公开(公告)号:US20070154889A1

    公开(公告)日:2007-07-05

    申请号:US10567025

    申请日:2005-06-24

    申请人: Yixin Wang

    发明人: Yixin Wang

    IPC分类号: C12Q1/68 C12P19/34

    摘要: An assay for identifying a malignant melanocyte is conducted by determining whether differential expression of particular genes is indicative of melanoma exceed a cut-off value. The assay can be performed intra-operatively on lymph node tissue.

    摘要翻译: 通过确定特定基因的差异表达是否指示黑素瘤超过临界值来进行鉴定恶性黑素细胞的测定。 该测定可以在手术中在淋巴结组织上进行。

    Methods and materials for identifying the origin of a carcinoma of unknown primary origin
    18.
    发明申请
    Methods and materials for identifying the origin of a carcinoma of unknown primary origin 审中-公开
    用于鉴定原发性原发癌的起源的方法和材料

    公开(公告)号:US20070065859A1

    公开(公告)日:2007-03-22

    申请号:US11523495

    申请日:2006-09-19

    摘要: The present invention provides a method of identifying origin of a metastasis of unknown origin by obtaining a sample containing metastatic cells; measuring Biomarkers associated with at least two different carcinomas; combining the data from the Biomarkers into an algorithm where the algorithm normalizes the Biomarkers against a reference; and imposes a cut-off which optimizes sensitivity and specificity of each Biomarker, weights the prevalence of the carcinomas and selects a tissue of origin determining origin based on highest probability determined by the algorithm or determining that the carcinoma is not derived from a particular set of carcinomas; and optionally measuring Biomarkers specific for one or more additional different carcinoma, and repeating the steps for additional Biomarkers.

    摘要翻译: 本发明提供了通过获得含有转移细胞的样品来鉴定未知来源的转移起点的方法; 测量与至少两种不同癌相关的生物标志物; 将来自生物标志物的数据组合成算法,其中算法使生物标志物反对参考标准化; 并强加了一个优化每个生物标志物的灵敏度和特异性的临界值,对癌症的患病率进行加权,并根据算法确定的最高概率选择确定起源的组织,或者确定癌不是从特定的一组 癌; 并且任选地测量对一种或多种另外的不同癌特异性的生物标志物,并重复其它生物标志物的步骤。

    Colorectal cancer prognostics
    19.
    发明申请
    Colorectal cancer prognostics 审中-公开
    结直肠癌预后

    公开(公告)号:US20060063157A9

    公开(公告)日:2006-03-23

    申请号:US10782413

    申请日:2004-02-19

    申请人: Yixin Wang

    发明人: Yixin Wang

    IPC分类号: C12Q1/68

    摘要: A method of providing a prognosis of colorectal cancer is conducted by analyzing the expression of a group of genes. Gene expresson profiles in a variety of medium such as microarrays are included as are kits that contain them.

    摘要翻译: 通过分析一组基因的表达来进行提供结肠直肠癌预后的方法。 包括微阵列在内的各种培养基中的基因表达谱也包含在其中。