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    Dispensing assembly
    12.
    发明授权
    Dispensing assembly 有权

    公开(公告)号：US10265484B2

    公开(公告)日：2019-04-23

    申请号：US14430710

    申请日：2013-09-24

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Adam J Stuart ,  Adam S. Cantor

    IPC: A61M15/00 ,  C09J7/20 ,  C09J7/38

    Abstract: A dispensing assembly for a container filled with a medicinal substance or formulation, the container being suitable for administering the medicinal substance or formulation via inhalation, buccal or sublingual delivery. The dispensing assembly includes a housing (1) defining a patient port through which, in use, the medicinal substance or formulation is dispensed. The dispensing assembly further includes a cap (3) that can be engaged with and disengaged from the patient port to close and open the patient port and an adhesive tape (10) having one portion (12) affixed to the housing and a second portion (11) affixed to the cap, such that when the cap is disengaged from the patient port, the cap is still connected to the housing.

    INTEGRATED MICRONEEDLE ARRAY DELIVERY SYSTEM
    14.
    发明申请
    INTEGRATED MICRONEEDLE ARRAY DELIVERY SYSTEM 有权
    集成式麦克风输送系统

    公开(公告)号：US20140257187A1

    公开(公告)日：2014-09-11

    申请号：US14350156

    申请日：2012-10-09

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： David J. Colburn ,  Erik J. Johnson ,  David H. Brandwein ,  Jerome E. Gysbers ,  Patrick J. Young ,  Adam S. Cantor

    IPC: A61M37/00

    CPC classification number: A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0046

    Abstract: The present disclosure provides a low-profile system and methods for delivering a microneedle array. The delivery system includes a housing that may be secured to and temporarily worn on a patient's skin. A carrier assembly coupled to a microneedle array is received in the housing proximate an applicator device. The carrier assembly is at least releasably secured to the housing and it is typically not attached or otherwise fixed to any portion of the applicator device.

    Abstract translation: 本公开提供了一种用于传送微针阵列的低调系统和方法。 输送系统包括可以固定到患者皮肤上并临时佩戴在患者皮肤上的壳体。 耦合到微针阵列的载体组件容纳在靠近施加器装置的壳体中。 载体组件至少可释放地固定到壳体上，并且其通常不附着或以其它方式固定到施用器装置的任何部分。

    TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING FENTANYL
    16.
    发明申请
    TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING FENTANYL 审中-公开

    公开(公告)号：US20180263920A1

    公开(公告)日：2018-09-20

    申请号：US15537579

    申请日：2015-12-17

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Amy Preszler Prince ,  Adam S. Cantor ,  Stephen J. Woehrle ,  John R. Hart ,  James P. DiZio ,  Sarah A. Sykora ,  Michael L. Husberg

    IPC: A61K9/70 ,  A61K31/4468

    CPC classification number: A61K9/7061 ,  A61K9/7069 ,  A61K31/4468

    Abstract: A transdermal drug delivery device includes a backing and an adhesive composition disposed on the backing. The adhesive composition includes a copolymer having at least 50 percent by weight C4 to C10 alkyl acrylate units, based on the total weight of the copolymer, and one or more second monomer units selected from the group consisting of vinyl acetate, acrylamide, ethyl acrylate, methyl acrylate, and N-vinyl-2-pyrrolidone. The C4 to C10 alkyl acrylate and the one or more second monomer units together make up at least 98 percent by weight of the copolymer. The adhesive composition further includes a skin permeation enhancer in a range from 5 percent to 25 percent by weight, based on the total weight of the adhesion composition, and fentanyl. The adhesive composition is substantially free of undissolved fentanyl. A method of treating a mammal including placing the transdermal drug delivery device on the mammal's skin is also disclosed.

    Composition for the Transdermal Delivery of Fentanyl
    17.
    发明申请
    Composition for the Transdermal Delivery of Fentanyl 审中-公开
    芬太尼透皮给药组合物

    公开(公告)号：US20170035704A1

    公开(公告)日：2017-02-09

    申请号：US15298891

    申请日：2016-10-20

    Applicant: 3M Innovative Properties Company

    Inventor： Adam S. Cantor ,  Terrance W. Ocheltree ,  Cynthia A. Robles

    IPC: A61K9/70 ,  A61K9/00 ,  A61K31/4468

    CPC classification number: A61K9/7061 ,  A61K9/0014 ,  A61K9/7084 ,  A61K31/44 ,  A61K31/4468

    Abstract: A transdermal drug delivery composition comprises an acrylate copolymer and from about 8% to about 30% by weight fentanyl. A transdermal fentanyl delivery composition comprising methyl laurate or tetraglycol as a permeation enhancer is also provided. The transdermal drug delivery compositions can be used to make a transdermal drug delivery device for the delivery of fentanyl.

    Abstract translation: 透皮药物递送组合物包含丙烯酸酯共聚物和约8％至约30％重量的芬太尼。 还提供了包含月桂酸甲酯或四甘醇作为渗透促进剂的透皮芬太尼递送组合物。 透皮药物递送组合物可用于制备用于递送芬太尼的透皮药物递送装置。

    Transdermal adhesive patch assembly with removable microneedle array and method of using same
    18.
    发明授权
    Transdermal adhesive patch assembly with removable microneedle array and method of using same 有权
    具有可移除微针阵列的透皮贴剂组件及其使用方法

    公开(公告)号：US09144671B2

    公开(公告)日：2015-09-29

    申请号：US14352327

    申请日：2012-12-12

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Adam S. Cantor ,  Andrew J. Stockholm

    IPC: A61M31/00 ,  A61M37/00 ,  A61K9/70

    CPC classification number: A61M37/0015 ,  A61K9/703 ,  A61K9/7084 ,  A61M2037/0023 ,  A61M2037/0061

    Abstract: A transdermal adhesive patch assembly and method of using same. The assembly can include a backing, and an adhesive and a matrix coupled to the backing. The matrix can include an active ingredient. The assembly can further include a microneedle array in at least partially overlapping relationship with the matrix; and a carrier that couples the microneedle array to the matrix opposite the backing, wherein the carrier and the microneedle array form a skin treatment assembly that, along with the matrix, can be located on a flap. The method can include adhering at least a portion of the adhesive to skin to form an anchor; applying pressure adjacent the microneedle array to treat an area of the skin; moving the flap away from the skin; removing the skin treatment assembly to expose the matrix; and replacing the flap to position the matrix over the treated area of the skin.

    Abstract translation: 透皮贴剂组件及其使用方法。 该组件可以包括背衬，和粘合剂以及耦合到背衬的矩阵。 基质可以包括活性成分。 组件还可以包括与基质至少部分重叠的关系的微针阵列; 以及将微针阵列耦合到与背衬相对的矩阵的载体，其中载体和微针阵列形成皮肤治疗组件，其与基质一起可以位于瓣上。 该方法可以包括将粘合剂的至少一部分粘附到皮肤上以形成锚固件; 在微针阵列附近施加压力以治疗皮肤的一部分; 将皮瓣从皮肤上移开; 去除皮肤处理组件以暴露基质; 并更换皮瓣以将基质定位在皮肤的治疗区域上。

    DISPENSING ASSEMBLY
    19.
    发明申请
    DISPENSING ASSEMBLY 审中-公开
    分配总成

    公开(公告)号：US20150246187A1

    公开(公告)日：2015-09-03

    申请号：US14430710

    申请日：2013-09-24

    Applicant: Adam J. STUART ,  Adam S. CANTOR ,  3M INNOVATIVE PROPERTIES COMPANY

    Inventor： Adam J Stuart ,  Adam S. Cantor

    IPC: A61M15/00 ,  C09J7/02

    CPC classification number: A61M15/0001 ,  A61M15/0026 ,  A61M15/0065 ,  A61M2207/00 ,  C09J7/20 ,  C09J7/38 ,  C09J2201/28 ,  C09J2201/622 ,  C09J2400/24 ,  C09J2433/00

    Abstract: A dispensing assembly for a container filled with a medicinal substance or formulation, the container being suitable for administering the medicinal substance or formulation via inhalation, buccal or sublingual delivery. The dispensing assembly includes a housing (1) defining a patient port through which, in use, the medicinal substance or formulation is dispensed. The dispensing assembly further includes a cap (3) that can be engaged with and disengaged from the patient port to close and open the patient port and an adhesive tape (10) having one portion (12) affixed to the housing and a second portion (11) affixed to the cap, such that when the cap is disengaged from the patient port, the cap is still connected to the housing.

    Abstract translation: 用于容纳药物或制剂的容器的分配组件，所述容器适于通过吸入，颊或舌下递送施用药物或制剂。 分配组件包括限定患者端口的壳体（1），在使用中，分配药物或制剂。 分配组件还包括能够与患者端口接合和脱离以关闭和打开患者口的帽（3），以及具有固定到壳体的一个部分（12）的粘合带（10）和第二部分 11）固定到盖上，使得当帽与患者端口脱离时，帽仍然连接到壳体。

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