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公开(公告)号：US12186536B2
公开(公告)日：2025-01-07
申请号：US17323830
申请日：2021-05-18
Applicant: AMGEN INC.
Inventor： Hans Stenberg Knudsen , Christian Plambech , Rasmus Øhlenschlæger , Jørgen Jørgensen
Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.
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公开(公告)号：US11904143B2
公开(公告)日：2024-02-20
申请号：US16609466
申请日：2018-06-04
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhlenschlaeger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
CPC classification number: A61M5/3145 , A61M5/20 , A61M5/31583 , A61M2005/3143
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：US20240238529A1
公开(公告)日：2024-07-18
申请号：US18409480
申请日：2024-01-10
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhlenschlæger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
CPC classification number: A61M5/3145 , A61M5/20 , A61M5/31583 , A61M2005/3143
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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Patent Agency Ranking
公开(公告)号：USD1010107S1
公开(公告)日：2024-01-02
申请号：US29848003
申请日：2022-07-29
Applicant: AMGEN INC.
Designer： Matias Melander , Bjarke Lykke Ludvig Svendsen , Christian Plambech , Dylan Bourelle , Jakob Halkjaer Pedersen , Joshua J. Dudman , Emil Gram Spork
Abstract: FIG. 1 is a perspective view showing a new design for a handheld drug delivery device;
FIG. 2 is a front view of the handheld drug delivery device of FIG. 1;
FIG. 3 is a rear view of the handheld drug delivery device of FIG. 1;
FIG. 4 is a right-side view of the handheld drug delivery device of FIG. 1;
FIG. 5 is a left-side view of the handheld drug delivery device of FIG. 1;
FIG. 6 is a top view of the handheld drug delivery device of FIG. 1;
FIG. 7 is a bottom view of the handheld drug delivery device of FIG. 1; and,
FIG. 8 is a perspective view of the handheld drug delivery device of FIG. 1 with its cap removed.
The broken lines show portions of the handheld drug delivery device that form no part of the claimed design.-
公开(公告)号：US20230138654A1
公开(公告)日：2023-05-04
申请号：US16609466
申请日：2018-06-04
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhelschlaeger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：US20210268192A1
公开(公告)日：2021-09-02
申请号：US17323830
申请日：2021-05-18
Applicant: AMGEN INC.
Inventor： Hans Stenberg Knudsen , Christian Plambech , Rasmus Øhlenschlæger , Jørgen Jørgensen
Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.
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公开(公告)号：US20180304014A1
公开(公告)日：2018-10-25
申请号：US15762939
申请日：2016-10-28
Applicant: AMGEN INC.
Inventor： Hans Stenberg Knudsen , Christian Plambech , Rasmus Øhlenschlæger , Jørgen Jørgensen
CPC classification number: A61M5/2033 , A61M5/1454 , A61M5/3204 , A61M5/326 , A61M2005/14256 , A61M2005/14506 , A61M2005/206 , A61M2005/31518 , A61M2005/3267
Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.
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公开(公告)号：US20240390599A1
公开(公告)日：2024-11-28
申请号：US18789085
申请日：2024-07-30
Applicant: AMGEN INC.
Inventor： Christian Plambech , Matias Melander , Bjarke Lykke Ludvig Svendsen , Joshua Jay Dudman , Michael Sorensen , Margaux Frances Boyaval , Avon Kuo
Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.
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