公开(公告)号：US11738146B2

公开(公告)日：2023-08-29

申请号：US15931364

申请日：2020-05-13

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler ,  Jimmie L. Ward ,  Christopher R. Folk ,  Steven William Badelt

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/142 ,  A61M5/50 ,  G16H20/17 ,  G16H40/63 ,  G16H40/00 ,  G16H40/67 ,  G06Q50/22 ,  G06Q50/00 ,  A61M5/158 ,  A61M5/24

CPC classification number: A61M5/20 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/24 ,  A61M5/31501 ,  A61M5/31568 ,  A61M5/3202 ,  A61M5/326 ,  A61M5/3243 ,  A61M5/3257 ,  A61M5/5086 ,  G06Q50/01 ,  G06Q50/22 ,  G16H20/17 ,  G16H40/00 ,  G16H40/63 ,  G16H40/67 ,  A61M2005/3267 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/6009

Abstract: A drug delivery system is disclosed that includes a drug delivery device having a reservoir and a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient. The drug delivery system may further include one or more sensors coupled to the drug delivery device, a wireless transmitter, and a controller coupled to the one or more sensors and the wireless transmitter. The controller may be configured to use the one or more sensors to determine a condition or an operational state of the drug delivery device, and control the wireless transmitter to wirelessly transmit one or more reports representative of the condition or the operational state of the drug delivery device. A method for use with a drug delivery device is also disclosed.

公开(公告)号：US20230201461A1

公开(公告)日：2023-06-29

申请号：US18111064

申请日：2023-02-17

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Basel Hasan Taha ,  Jimmie L. Ward ,  Christopher R. Folk ,  Steven William Badelt ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/142 ,  A61M5/50 ,  G16H20/17 ,  G16H40/63 ,  G16H40/00 ,  G16H40/67 ,  G06Q50/22 ,  G06Q50/00 ,  A61M5/158 ,  A61M5/24

CPC classification number: A61M5/20 ,  A61M5/31501 ,  A61M5/3243 ,  A61M5/326 ,  A61M5/14248 ,  A61M5/5086 ,  G16H20/17 ,  G16H40/63 ,  G16H40/00 ,  G16H40/67 ,  G06Q50/22 ,  A61M5/31568 ,  G06Q50/01 ,  A61M5/14244 ,  A61M5/158 ,  A61M5/24 ,  A61M5/3202 ,  A61M5/3257 ,  A61M2005/3267 ,  A61M2205/3368 ,  A61M2205/6009 ,  A61M2205/3331 ,  A61M2205/3553 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/3576

Abstract: Systems and methods are disclosed for processing sensor data collected by a drug delivery device with an external computing device. The drug delivery device may include a reservoir and a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient. The drug delivery device may further include one or more sensors configured to generate sensor data representative of a condition and/or operational state of the drug delivery device, and a communication module configured to transmit information to the external computing device. The external computing device may process the information received from the drug delivery device according to information stored in a memory of the external computing device to determine the condition or the operational state of the drug delivery device and/or generate instructional or informational prompts to be displayed to a user or patient.

公开(公告)号：US10646652B2

公开(公告)日：2020-05-12

申请号：US15315829

申请日：2015-06-03

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler ,  Basel Hasan Taha ,  Jimmie L. Ward ,  Christopher R. Folk ,  Steven William Badelt

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/142 ,  G06Q50/22 ,  A61M5/50 ,  G06F19/00 ,  G06Q50/00 ,  A61M5/158 ,  A61M5/24

Abstract: A drug delivery system is disclosed that includes a drug delivery device having a reservoir, a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient, and one or more controllable elements. The drug delivery system may further include one or more sensors coupled to the drug delivery device, and a controller coupled to the one or more sensors and the one or more controllable elements. The controller may be configured to use the one or more sensors to determine a condition or an operational state of the drug delivery device. Furthermore, the controller may be configured to control the controllable element based on the condition or the operational state of the drug delivery device and/or identity information stored in a memory onboard the device. A method for use with a drug delivery device is also disclosed.

公开(公告)号：US20170098058A1

公开(公告)日：2017-04-06

申请号：US15315896

申请日：2015-06-03

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler ,  Basel Hasan Taha ,  Jimmie L. Ward ,  Christopher R. Folk ,  Steven William Badelt

IPC: G06F19/00 ,  A61M5/315 ,  A61M5/32 ,  A61M5/20

CPC classification number: A61M5/20 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/24 ,  A61M5/31501 ,  A61M5/31568 ,  A61M5/3202 ,  A61M5/3243 ,  A61M5/3257 ,  A61M5/326 ,  A61M5/5086 ,  A61M2005/3267 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/6009 ,  G06F19/325 ,  G06F19/3418 ,  G06F19/3468 ,  G06Q50/01 ,  G06Q50/22

Abstract: Systems and methods are disclosed for processing sensor data collected by a drug delivery device with an external computing device. The drug delivery device may include a reservoir and a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient. The drug delivery device may further include one or more sensors configured to generate sensor data representative of a condition and/or operational state of the drug delivery device, and a communication module configured to transmit information to the external computing device. The external computing device may process the information received from the drug delivery device according to information stored in a memory of the external computing device to determine the condition or the operational state of the drug delivery device and/or generate instructional or informational prompts to be displayed to a user or patient.

公开(公告)号：US20220184318A1

公开(公告)日：2022-06-16

申请号：US17437615

申请日：2020-04-10

Applicant: AMGEN INC.

Inventor： Azita Rahbari ,  Sunitha Dasoju ,  Angelo Tosarini ,  Antonio Antonini ,  Julian Jazayeri ,  Harpreet Sachar ,  Andrew Coles ,  Desheng Yin ,  Alireza Ashani

IPC: A61M5/315 ,  A61M5/32 ,  A61M5/24

Abstract: A cassette for a drug delivery device is described that includes a sleeve, a syringe having a barrel disposed in the sleeve, and a plunger-stopper slidably disposed within the barrel. An end cap is adapted to couple to the sleeve to secure the syringe in the sleeve. The cassette further includes a spacer that is sized to be slidably moved within the barrel and the spacer is disposed distal to the plunger-stopper to be engaged by a plunger rod to slide within the barrel and engage the plunger-stopper. In some forms, the spacer can be coupled to the end cap.

公开(公告)号：US10695492B2

公开(公告)日：2020-06-30

申请号：US15315817

申请日：2015-06-03

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler ,  Jimmie L. Ward ,  Christopher R. Folk ,  Steven William Badelt

IPC: A61M5/50 ,  A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/142 ,  G06Q50/22 ,  G06F19/00 ,  G06Q50/00 ,  A61M5/158 ,  A61M5/24

Abstract: A drug delivery system is disclosed that includes a drug delivery device having a reservoir and a delivery cannula having a proximal end in fluid communication with the reservoir and a distal end to be received within a patient. The drug delivery system may further include one or more sensors coupled to the drug delivery device, a wireless transmitter, and a controller coupled to the one or more sensors and the wireless transmitter. The controller may be configured to use the one or more sensors to determine a condition or an operational state of the drug delivery device, and control the wireless transmitter to wirelessly transmit one or more reports representative of the condition or the operational state of the drug delivery device. A method for use with a drug delivery device is also disclosed.

公开(公告)号：US20180318526A1

公开(公告)日：2018-11-08

申请号：US15775630

申请日：2016-12-09

Applicant: AMGEN INC.

Inventor： Huaying Yang ,  Desheng Yin ,  Ferry Tamtoro ,  Scott Robert Gibson ,  Keith P. Kogler ,  Michael Friedman ,  Neal Johnston ,  Adam B. McCullough

IPC: A61M5/50 ,  A61M5/24 ,  A61M5/32 ,  A61M5/20 ,  A61K38/19 ,  C07K16/40 ,  C07K14/705 ,  A61K38/17 ,  C07K16/28

CPC classification number: A61M5/5086 ,  A61K38/1793 ,  A61K38/193 ,  A61M5/2033 ,  A61M5/2466 ,  A61M5/3204 ,  A61M5/326 ,  A61M5/3286 ,  A61M2005/2086 ,  A61M2005/3104 ,  A61M2205/13 ,  A61M2205/14 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/36 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/609 ,  A61M2205/8206 ,  A61M2205/8212 ,  C07K14/70578 ,  C07K16/2803 ,  C07K16/40 ,  C07K2317/31 ,  C07K2319/30 ,  G06F19/00 ,  G06F19/3468

Abstract: A drug delivery device includes a housing defining a shell, a drug delivery assembly at least partially disposed within the housing, a cap defining an opening and being adapted to at least partially cover an end of the housing, at least one electronic component, a power source which powers the electronic component, and a switch assembly. The drug delivery assembly comprises a guard which engages an inner surface of the housing and is movable between a first, a second, and a third position relative to the housing and are adapted to restrict external contact with a cannula. The switch assembly causes the power source to provide power to the electronic component when the cap is removed from the housing, restrict the power source from providing power when the cap is coupled to the housing and the guard is in the first position, and cause the power source to provide power when the cap is coupled to the housing and the guard is in the third position.

公开(公告)号：US20170103186A1

公开(公告)日：2017-04-13

申请号：US15315954

申请日：2015-06-03

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler ,  Basel Hasan Taha ,  Jimmie L. Ward ,  Steven William Badelt

IPC: G06F19/00 ,  A61M5/32 ,  A61M5/20 ,  A61M5/315 ,  G06Q50/00 ,  A61M5/142

CPC classification number: A61M5/20 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/158 ,  A61M5/24 ,  A61M5/31501 ,  A61M5/31568 ,  A61M5/3202 ,  A61M5/3243 ,  A61M5/3257 ,  A61M5/326 ,  A61M5/5086 ,  A61M2005/3267 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/3553 ,  A61M2205/3576 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/6009 ,  G06F19/325 ,  G06F19/3418 ,  G06F19/3468 ,  G06Q50/01 ,  G06Q50/22

Abstract: Systems and methods are disclosed herein for supporting a patient's use of a drug delivery device. The patient may be associated with a support group via, for example, a social networking service for the purpose of increasing the likelihood that the patient will comply with a treatment regimen. Based on data representative of a condition and/or operational state of the drug delivery device, it may be determined whether the patient is compliant with the treatment regimen. If the patient is not compliant, the systems and method disclosed herein may transmit a communication to the support group requesting the support group to counsel the patient about the treatment regimen. The counseling may take the form of words of encouragement, coaching, suggestions, reminders, and/or any other communication likely to urge the patient to comply with the treatment regimen.

公开(公告)号：US20230098606A1

公开(公告)日：2023-03-30

申请号：US17940422

申请日：2022-09-08

Applicant: AMGEN INC.

Inventor： Adam B. McCullough ,  Basel Hasan Taha ,  Jimmie L. Ward ,  Steven William Badelt ,  Ferry Tamtoro ,  Huaying Yang ,  Mark Ka Lai Lee ,  Desheng Yin ,  Scott R. Gibson ,  Donald Busby ,  Peter V. Shultz ,  Keith P. Kogler

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/142 ,  A61M5/50 ,  G16H20/17 ,  G16H40/63 ,  G16H40/00 ,  G16H40/67 ,  G06Q50/22 ,  G06Q50/00 ,  A61M5/158 ,  A61M5/24

Abstract: Devices and methods are disclosed for assisting a user of a drug delivery device with an application executing on a mobile computing device. The mobile computing device may receive information from the drug delivery device related to its condition and/or operation and subsequently select an informational and/or instructional prompt to be displayed to the user based on the received information. The mobile computing device may also generate a display in the application including the selected informational prompt and/or the instructional prompt. Accordingly, the user of the drug delivery device can be guided through the drug delivery process in real time, thereby reducing the likelihood of improper or incomplete use of the drug delivery device.

公开(公告)号：US20220362484A1

公开(公告)日：2022-11-17

申请号：US17767111

申请日：2020-10-05

Applicant: AMGEN INC.

Inventor： Desheng Yin ,  Huixing Jin ,  Huaying Yang ,  Zhuo M. Cai ,  Alireza Ashani

IPC: A61M5/32 ,  A61M5/20 ,  A61M5/315

Abstract: The present disclosure relates to a drug delivery device. The drug delivery device includes a housing having a proximal end and a distal end. Additionally, a needle guard disposed at the proximal end of the housing and movable in an axial direction relative the housing between a first position and a second position. A storage container, disposed within the housing for storing a drug, includes a needle for administering the drug. The drug delivery device also includes an injection activation button disposed on the distal end of the housing and including a fingerprint detector. Additionally, the present disclosure includes a lock configured to switch between a locked configuration inhibiting actuation of the drug delivery device and an unlocked configuration enabling actuation of the delivery device. The lock is in the unlocked configuration when the needle guard is in the second position and the fingerprint detector detects a fingerprint.