公开(公告)号：US20220015949A1

公开(公告)日：2022-01-20

申请号：US17057691

申请日：2020-04-08

Applicant: AMO Development, LLC

Inventor： Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Phillip Gooding ,  Richard Hofer ,  Georg Schuele

IPC: A61F9/008 ,  G02B26/10

Abstract: The XYZ beam position of an ophthalmic laser system is calibrated by measuring a fluorescent signal induced by the focused laser beam in a thin glass coverslip via multiphoton absorption. A video camera measures the XY position and intensity of the fluorescent signal as the focused laser beam strikes the coverslip. The Z position of the focus is determined by scanning the targeted z position and identifying the Z scanner position of peak fluorescence. An OCT system measures the real space Z location of the coverslip, which is correlated with the Z scanner position. Other laser system parameters are assessed by repeatedly scanning a lower energy laser beam in a piece of IOL material, and observing damage (scattering voids) formation in the IOL material. Based on the rate of damage formation, laser system parameters such as beam quality, numerical aperture, pulse energy, and pulse duration, etc. can be assessed.

公开(公告)号：US11154424B2

公开(公告)日：2021-10-26

申请号：US16375784

申请日：2019-04-04

Applicant: AMO Development, LLC

Inventor： Georg Schuele ,  Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Tianheng Wang ,  Michael Wiltberger ,  Mihai State ,  Phillip Gooding

IPC: A61F2/16 ,  A61F9/008 ,  B29D11/02 ,  B29C71/04 ,  G02C7/02 ,  B29D11/00 ,  B29C35/08

Abstract: A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone.

公开(公告)号：US11833031B2

公开(公告)日：2023-12-05

申请号：US17057687

申请日：2020-04-09

Applicant: AMO Development, LLC

Inventor： Georg Schuele ,  David A. Dewey ,  Jenny Wang ,  Richard Hofer ,  Alexander Vankov

IPC: A61F2/16 ,  A61F9/008 ,  B29D11/02

CPC classification number: A61F2/1656 ,  A61F9/008 ,  B29D11/023 ,  A61F2009/00897 ,  A61F2240/001

Abstract: A laser scanning method for forming a Fresnel type gradient index lens in an intraocular lens IOL. The radial profile of the desired optical pathlength (OPL) difference to be achieved in the IOL has multiple zones, each zone ramping from unchanged OPL to one wave, and stepping down to zero. To form a zone of a predefined OPL difference profile, the laser beam is scanned in multiple passes; in each pass, the laser beam is scanned in concentric circles of varying radii covering all or a part of the zone, with laser energy ramping up (along the radius) to a maximum allowed energy and staying at that energy. The ramp up region, which is dependent on the predefined OPL difference profile and the maximum allowed energy, is short, and most part of the pass is scanned at the maximum allowed energy.

公开(公告)号：US11793675B2

公开(公告)日：2023-10-24

申请号：US17451812

申请日：2021-10-21

Applicant: AMO Development, LLC

Inventor： Georg Schuele ,  Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Tianheng Wang ,  Michael Wiltberger ,  Mihai State ,  Phillip Gooding

IPC: A61F9/008 ,  A61F2/16 ,  B29D11/02 ,  B29C71/04 ,  G02C7/02 ,  B29D11/00 ,  B29C35/08

CPC classification number: A61F9/008 ,  A61F2/16 ,  A61F2/1602 ,  A61F2/164 ,  A61F2/1627 ,  B29C71/04 ,  B29D11/00461 ,  B29D11/023 ,  G02C7/022 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2002/1681 ,  A61F2009/0087 ,  A61F2009/00842 ,  A61F2009/00851 ,  A61F2250/0053 ,  A61L2430/16 ,  B29C2035/0838 ,  B29C2791/009 ,  B29K2995/0031 ,  G02C2202/12

Abstract: A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone.

公开(公告)号：US20230021864A1

公开(公告)日：2023-01-26

申请号：US17937763

申请日：2022-10-03

Applicant: AMO Development, LLC

Inventor： Jenny Wang ,  Tianheng Wang ,  David Dewey ,  Michael Wiltberger ,  Alexander Vankov ,  Phillip Gooding ,  Georg Schuele

IPC: A61F9/008

Abstract: A full depth ophthalmic surgical system includes a femtosecond laser source and an optical coherence tomographer. The system is capable of performing surgical procedures along the entire length of the eye from the cornea to the retina. The optical system of the ophthalmic surgical system is optimized to focus the laser beam and imaging light in the vitreous humor of the eye. In some embodiments, the system includes a video camera with a tunable lens before it to image the entire length of the eye. For procedures performed posterior to the lens, a method for calibrating the full depth ophthalmic surgical system is also provided. The system can be used to perform treatment in the vitreous humor, including treating floaters and liquification of the vitreous humor.

公开(公告)号：US20220031504A1

公开(公告)日：2022-02-03

申请号：US17451812

申请日：2021-10-21

Applicant: AMO Development, LLC

Inventor： Georg Schuele ,  Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Tianheng Wang ,  Michael Wiltberger ,  Mihai State ,  Phillip Gooding

IPC: A61F9/008 ,  A61F2/16 ,  B29C71/04 ,  B29D11/00 ,  B29D11/02 ,  G02C7/02

Abstract: A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone.

公开(公告)号：US20220015948A1

公开(公告)日：2022-01-20

申请号：US17057689

申请日：2020-04-07

Applicant: AMO Development, LLC

Inventor： Richard Hofer ,  Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Phillip Gooding ,  Georg Schuele

IPC: A61F9/008 ,  A61L27/16

Abstract: Methods and related apparatus for real-time process monitoring during laser-based refractive index modification of an intraocular lens. During in situ laser treatment of the IOL to modify the refractive index of the IOL material, a signal from the IOL is measured to determine the processing effect of the refractive index modification, and based on the determination, to adjust the laser system parameters to achieve intended processing result. The signal measured from the IOL may be a fluorescent signal induced by the treatment laser, a fluorescent signal induced by an external illumination source, a temporary photodarkening effect, a color change, or a refractive index change directly measured by phase stabilized OCT.

公开(公告)号：US11020274B2

公开(公告)日：2021-06-01

申请号：US16359907

申请日：2019-03-20

Applicant: AMO Development, LLC

Inventor： Alexander Vankov

IPC: A61F9/008 ,  A61F9/007 ,  A61F9/009

Abstract: Systems and methods for fragmenting a lens by a laser cataract surgery system includes a sub-nanosecond laser source generating a treatment beam that includes a plurality of laser beam pulses. An optical delivery system is coupled to the sub-nanosecond laser source to receive and direct the treatment beam. A processor is coupled to the sub-nanosecond laser source and the optical delivery system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine a lens cut pattern for lens fragmentation and determine a plurality of energies of the treatment beam as a linear function of a depth of the lens cut pattern. The treatment beam is output according to the lens cut pattern and the determined energies.

公开(公告)号：US20200261269A1

公开(公告)日：2020-08-20

申请号：US16868481

申请日：2020-05-06

Applicant: AMO Development, LLC

Inventor： Jenny Wang ,  Tianheng Wang ,  David Dewey ,  Michael Wiltberger ,  Alexander Vankov ,  Phillip Gooding ,  Georg Schuele

IPC: A61F9/008

Abstract: A full depth ophthalmic surgical system includes a femtosecond laser source and an optical coherence tomographer. The system is capable of performing surgical procedures along the entire length of the eye from the cornea to the retina. The optical system of the ophthalmic surgical system is optimized to focus the laser beam and imaging light in the vitreous humor of the eye. In some embodiments, the illumination light source and the scanning mirrors are imaged by the system's objective lens and the patient interface lens to locations near the pupil, to increase the volume of the vitreous humor reachable by the illumination light and laser beam. For procedures performed posterior to the lens, a method for calibrating the full depth ophthalmic surgical system is also provided. The system can be used to perform treatment in the vitreous humor, including treating floaters and liquification of the vitreous humor.

公开(公告)号：US20250025344A1

公开(公告)日：2025-01-23

申请号：US18907307

申请日：2024-10-04

Applicant: AMO Development, LLC

Inventor： Richard Hofer ,  Alexander Vankov ,  Jenny Wang ,  David A. Dewey ,  Phillip Gooding ,  Georg Schuele

IPC: A61F9/008 ,  A61B17/00 ,  A61L27/16

Abstract: Methods and related apparatus for real-time process monitoring during laser-based refractive index modification of an intraocular lens. During in situ laser treatment of the IOL to modify the refractive index of the IOL material, a signal from the IOL is measured to determine the processing effect of the refractive index modification, and based on the determination, to adjust the laser system parameters to achieve intended processing result. The signal measured from the IOL may be a fluorescent signal induced by the treatment laser, a fluorescent signal induced by an external illumination source, a temporary photodarkening effect, a color change, or a refractive index change directly measured by phase stabilized OCT.