公开(公告)号：US10716705B2

公开(公告)日：2020-07-21

申请号：US14968618

申请日：2015-12-14

Applicant: AMO Development, LLC

Inventor： Hong Fu

IPC: A61B18/20 ,  A61F9/008 ,  A61F9/009

Abstract: Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for photorefractive keratectomy. In an embodiment, an ophthalmic surgical laser system comprises a laser source generating a pulsed laser beam and a laser delivery system delivering the pulsed laser beam to a cornea of an eye. A patient interface couples to and constrains the eye relative to the laser delivery system. A controller controls the laser delivery system to perform an anterior surface volume dissection on the cornea.

公开(公告)号：US10709611B2

公开(公告)日：2020-07-14

申请号：US16109654

申请日：2018-08-22

Applicant: AMO Development, LLC

Inventor： Hong Fu ,  Alireza Malek Tabrizi

IPC: A61F9/008 ,  A61B3/107 ,  A61B3/00

Abstract: Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in the subject's eye, where each of the top and bottom lenticular incision includes a center spherical portion and an edge transition portion that is not located on the same spherical surface as the spherical portion but has a steeper shape.

公开(公告)号：US10690486B2

公开(公告)日：2020-06-23

申请号：US16027137

申请日：2018-07-03

Applicant: AMO DEVELOPMENT, LLC

Inventor： Zheng Sun ,  Daniel Bray ,  Zenon Witowski ,  Timothy Slotterback ,  Hong Fu

IPC: G01B11/24

Abstract: A measurement apparatus for measuring a laser focus spot size, which includes a two-dimensional image detector and an imaging system which forms a magnified image of a focus spot located an object plane onto the image detector. The imaging system includes at least an objective lens. A sealed liquid container is secured over a part of the objective lens such as the optical surface of the objective lens is immersed in the liquid (e.g. water) within the container. The liquid container has a window through which the laser beam enters. An image processing method is also disclosed which processes the image obtained by the image detector to obtain the focus spot size while implementing an algorithm that corrects for the effect of ambient vibration.

公开(公告)号：US20200011659A1

公开(公告)日：2020-01-09

申请号：US16027137

申请日：2018-07-03

Applicant: AMO DEVELOPMENT, LLC

Inventor： Zheng Sun ,  Daniel Bray ,  Zenon Witowski ,  Timothy Slotterback ,  Hong Fu

IPC: G01B11/24

Abstract: A measurement apparatus for measuring a laser focus spot size, which includes a two-dimensional image detector and an imaging system which forms a magnified image of a focus spot located an object plane onto the image detector. The imaging system includes at least an objective lens. A sealed liquid container is secured over a part of the objective lens such as the optical surface of the objective lens is immersed in the liquid (e.g. water) within the container. The liquid container has a window through which the laser beam enters. An image processing method is also disclosed which processes the image obtained by the image detector to obtain the focus spot size while implementing an algorithm that corrects for the effect of ambient vibration.

公开(公告)号：US20180008461A1

公开(公告)日：2018-01-11

申请号：US15644564

申请日：2017-07-07

Applicant: AMO Development, LLC

Inventor： Hong Fu ,  Alireza Malek Tabrizi ,  Dimitri Chernyak ,  Guangming G. Dai ,  Daniel R. Neal ,  Thomas D. Raymond

IPC: A61F9/008 ,  A61B18/20 ,  A61B18/00

CPC classification number: A61F9/008 ,  A61B18/20 ,  A61B2018/00601 ,  A61F9/00827 ,  A61F9/00829 ,  A61F2009/00848 ,  A61F2009/00872 ,  A61F2009/0088 ,  A61F2009/00882 ,  A61F2009/00897

Abstract: Embodiments generally relate to systems and methods for lenticular laser incisions based on wavefront maps. In an embodiment, a method comprises obtaining a wavefront map of a free eye using wavefront aberrometry to measure a refractive error, obtaining an iris image for the free eye using wavefront aberrometry, determining a free eye cutting profile to cut the cornea based on the wavefront measurement, determining a first translation of the free eye cutting profile based on estimated perturbation of the eye with a docking patient interface, docking the eye to a patient interface of an ultrashort pulsed laser system, obtaining an iris image for the docked eye, determining a second translation of the cutting profile for the docked eye from the free eye, using comparisons between the two iris images, and incising a bottom surface incision in the cornea based on the two translated cutting profiles.

公开(公告)号：US20180000647A1

公开(公告)日：2018-01-04

申请号：US15638169

申请日：2017-06-29

Applicant: AMO Development, LLC

Inventor： Alireza Malek Tabrizi ,  Hong Fu ,  James E. Hill

IPC: A61F9/008 ,  A61B3/00

CPC classification number: A61F9/00827 ,  A61B3/0008 ,  A61F9/008 ,  A61F9/00825 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00897

Abstract: Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incisions to form a top lenticular incision, a bottom lenticular incision of a lens in the subject's eye, an added shape between the top and bottom incisions where the added shape has no corrective power and a transition ring bisecting both the top and bottom lenticular incisions.

公开(公告)号：US20160374857A1

公开(公告)日：2016-12-29

申请号：US14970898

申请日：2015-12-16

Applicant: AMO Development, LLC

Inventor： Hong Fu ,  Bryant M. Moore ,  Charles Vice

IPC: A61F9/008

Abstract: A compact system for performing laser ophthalmic surgery is disclosed. An embodiment of the system includes a mode-locked fiber oscillator-based ultra-short pulsed laser capable of producing laser pulses in the range of 1 nJ to 5 μJ at a pulse repetition rate of between 5 MHz and 25 MHz, a resonant optical scanner oscillating at a frequency of 200 Hz and 21000 Hz, a scan-line rotator, a movable XY-scan device, a z-scan device, and a controller configured to coordinate with the other components of the system to produce one or more desired incision patterns. The system also includes compact visualization optics for in-process monitoring using a beam-splitter inside the cone of a patient interface used to fixate the patient's eye during surgery. The system can be configured such that eye surgery is performed while the patient is either sitting upright, or lying on his or her back.

Abstract translation: 公开了一种用于执行激光眼科手术的紧凑系统。 该系统的一个实施例包括一种基于模式锁定光纤振荡器的超短脉冲激光器，其能够以5MHz和25MHz之间的脉冲重复频率产生1nJ至5μJ范围内的激光脉冲，共振光学扫描器 以200Hz和21000Hz的频率振荡，扫描线旋转器，可移动XY扫描装置，z扫描装置和被配置为与系统的其他部件协调以产生一个或多个所需切口的控制器 模式。 该系统还包括紧凑的可视化光学元件，用于在手术中使用用于固定患者眼睛的患者接口的锥体内的分束器进行进程内监测。 该系统可以被配置为使得在患者直立或躺在他或她的背部时进行眼科手术。

公开(公告)号：US20160089270A1

公开(公告)日：2016-03-31

申请号：US14865396

申请日：2015-09-25

Applicant: AMO Development, LLC

Inventor： Hong Fu

IPC: A61F9/008

CPC classification number: A61F9/00825 ,  A61F9/00827 ,  A61F9/00829 ,  A61F9/00834 ,  A61F9/0084 ,  A61F2009/00844 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00887 ,  A61F2009/00897

Abstract: Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in the subject's eye.

Abstract translation: 本发明的实施例一般涉及眼科激光程序，更具体地，涉及用于透镜激光切割的系统和方法。 在一个实施例中，眼科外科激光系统包括用于将脉冲激光束传送到受试者眼睛中的目标的激光递送系统，用于偏转脉冲激光束的XY扫描装置，Z扫描装置，以修改 脉冲激光束的焦点，以及控制器，被配置为在受检者的眼睛中形成透镜的顶部透镜切口和底部透镜切口。

公开(公告)号：US20140276680A1

公开(公告)日：2014-09-18

申请号：US14193740

申请日：2014-02-28

Applicant: AMO Development, LLC

Inventor： Anthony Dennison ,  Michael A. Campos ,  Hong Fu

IPC: A61F9/008

CPC classification number: A61F9/0084 ,  A61F9/00825 ,  A61F2009/00851 ,  A61F2009/00863 ,  A61F2009/0087 ,  A61F2009/00887

Abstract: Some embodiments disclosed here provide for a method fragmenting a cataractous lens of a patient's eye using an ultra-short pulsed laser. The method can include determining, within a lens of a patient's eye, a high NA zone where a cone angle of a laser beam with a high numerical aperture is not shadowed by the iris, and a low NA zone radially closer to the iris where the cone angle of the laser beam with a low numerical aperture is not shadowed by the iris. Laser lens fragmentation is accomplished by delivering the laser beam with the high numerical aperture to the high NA zone, and the laser beam with the low numerical aperture to the low NA zone. This can result in a more effective fragmentation of a nucleus of the lens without exposing the retina to radiation above safety standards.

Abstract translation: 这里公开的一些实施例提供了使用超短脉冲激光来分割病人眼睛的白内障透镜的方法。 该方法可以包括在患者眼睛的镜片内确定高NA区域，其中具有高数值孔径的激光束的锥角不被虹膜遮蔽，以及径向更靠近虹膜的低NA区域，其中 具有低数值孔径的激光束的锥角不被虹膜遮蔽。 激光透镜碎片通过将具有高数值孔径的激光束传递到高NA区域，并将具有低数值孔径的激光束传递到低NA区域来实现。 这可能导致镜片细胞核的更有效的分裂，而不会将视网膜暴露于高于安全标准的辐射。

公开(公告)号：US20250073080A1

公开(公告)日：2025-03-06

申请号：US18951058

申请日：2024-11-18

Applicant: AMO Development, LLC

Inventor： Nima Khatibzadeh ,  Li Bing ,  Hong Fu

IPC: A61F9/008 ,  A61B18/20

Abstract: An ophthalmic surgical laser system and method for forming a lenticule in a subject's eye using “fast-scan-slow-sweep” scanning scheme. A high frequency scanner forms a fast scan line, which is placed tangential to a parallel of latitude of the surface of the lenticule and then then moved in a slow sweep trajectory along a meridian of longitude of the surface of the lenticule in one sweep. Multiple sweeps are performed along different meridians to form the entire lenticule surface, with the orientation of the scan line rotated between successive sweeps. To generate tissue bridge free incisions without leaving laser-induced marks in the eye, a laser pulse energy between 40 nJ to 70 nJ is used, and the sweeping speed is controlled such that the scan line step (the distance between the centers of consecutive scan lines) is between 1.7 μm and 2.3 μm.